Size: px
Start display at page:

Download ""

Transcription

1

2

3

4

5

6

7

8

9

10

11 1) Ellis, R. W., PeFeo, D., Shih, T. Y., Gonda, M. A., Young, H. A., Tsuchida, N., Lowry, D. R., Scolnick, E. M.: Nature, 292, (1981) 2) Barbacid, M.: Annu. Rev. Biochem., 56, (1987) 3) Beckner, S. K., Hattori, S., Shih, T. Y.: Na ture,317, (1985) 4) Birchmeier, C., Broek, P., Wigler, M.: Cell, 43, (1985) 5) Trahey, M., McCormick, F.: Science, 238, (1987) 6) Der, C. J., Weissman, B., MacDonal, M. J.: Oncogene, 3, (1988) 7) Feig, L., Cooper, G. M.: Mol. Cell. Biol., 8, (1988) 8) Noda, M., Ko, M., Ogura, A., Liu, D. G., Ama no,t., Idawa, Y.: Nature, 318, (1985) 9) Satoh, T., Endo, M., Nakamura, S., Kaziro, Y.: FEBS Lett., 236, (1988) 10) Kamata, T., Kung, H-F.: Mol. Cell. Biol.., 10, (1990) 11) Gibbs, J. B., Schaber, M. D., Marshall, M. S., Scolnick, E. M., Sigal, I-S.: J. Biol. Chem., 262, (1987) 12) Hughes, D. A., Fukui, Y., Yamamoto, M.: Na ture,344, (1990) 13) Gibbs, J. B., Schaber, M. D., Allard, J., Sigal, I. S., Scolnick, E. M.: Proc. Natl. Acad. Sci. USA, 8, (1988) 14) Trahey, M., Wong, G., Halenback, R., Rubin feld,b., Martin, G. A., Lanrer, M., Long, C. M., Crosier, W. J., Watt, K., Koths, K., Mc- Cormick, F.: Science, 242, (1988) 15) McCormick, F.: Cell, 56, 5-8 (1989) 16) Tanaka, K., Nakafuku, M., Satoh, T., Mar shall,m., Gibbs, J., Matsumoto, K., Kaziro, Y., Toh-e, A.: Cell, 60, (1990) 17) Ballester, R., Michaeli, T., Ferguson, K., Xu, H, -P., McCornick, F., Wisler, M.: Cell, 59, (1989) 18) McCormick, F., Adari, H., Trahey, M., Halen beck, R., Koths, K., Martin, G. A., Crosier, W. J., Watt, K., Rubinfeld, B., Wong, G.: Cold Spring Harbor Symp. Quant. Biol., 53, (1988) 19) Hall, A.: Cell, 61, (1990) 20) Hall, A., Self, A. J.: J. Biol. Chem., 261, (1986) 21) Hoshino, M., Clanton, D. J., Shih, T. Y., Ka wakita,y., Hattori, S.: J. Biochem., 102, (1987) 22) Satoh, T., Nakamura, S., Nakafuku, M., Ka ziro,y.: Biochim. Biophys. Acta, 949, 97- (1988) 23) Satoh, T., Endo, M., Nakafuku, M., Nakamu ra,s., Kaziro, Y.: Proc. Natl. Acad. Sci. USA, 87, (1990) 24) Berridge, M. J., Irvine, R. F.: Nature, 341, (1989) 25) West, M., Kung, H. -F., Kamata, T.: FEBS Lett., 259, (1990) 26) Huang, Y. K., Kung, H-F., Kamata, T.: Proc. Natl. Acad. Sci. USA, 87, (1990) 27) Poe, M., Scolnick, E. M., Stein, R. B.: J. Biol. Chem., 260, (1985) 28) Maeno, M., Huang, Y. K., Kung, H-F., Kama ta,t.: Š e õ 29) Adari, H., Lowy, D. R., Willumser, B. M., Der, C. J., McCormick, F.: Science, 240, (1988) 30) Srivastava, S. K., Donato, A. D., Lacal, J. C.: Mol. Cell. Biol., 9, (1989) 31) Mulcathy, L. S., Smith, M. R., Stacey, D. W.: Nature, 313, (1985) 32) Smith, M. R., DeGudicibus, S. J., Stacey, D. W.: Nature, 320, (1986) 33) Sigal, I. S., Gibbs, J. B., D'Alonzo, J. S., Scol nick,e. M.: Proc. Natl. Acad. Sci. USA, 83, (1986) 34) Milburn, M. V., Tong, L., DeVos, A. M., Briin ger,a., Yamaizumi, Z., Nishimura, S., Kim, S-H.: Nature, 247, (1990) 35) Pai, E. F., Kabsch, W., Krengel, V., Holmes, K. C., John, J., Wittinghofer, A.: Nature, 341, (1989) 36) Jurnak, F., Heffron, S., Bergmann, E.: Cell, 60, (1990) 37) Cales, C., Hancock, J. F., Marshall, C. J., Hall, A.: Nature, 232, (1988) 38) Broek, D., Toda, T., Michael, L., Levin, C., Brichmeier, C., Zoller, M., Powers, S., Wisher, M.: Cell, 98, (1987) 39) Boy-Marcottee, Damak, F., Camonis, J., Gar vau,h., Jacquet, M.: Gene, 77, (1989) 40) Wigler, M., Field, J., Powers, S., Broek, D., Toda, T., Cameron, S., Nikawa, J., Michaell, J., Colicelli, J., Ferguson, K.: Cold Spring Harbor Symp. Quant. _ Biol., 53, (1988) 41) Sadhu, K., Reed, S. I., Richardson, H., Russell, P.: Proc. Natl. Acad. Sci. USA, 87, (1990) 42) Crechet, J-B., Poluliet, P., Mistou, M-Y., Par meggiani,a., Camonis, J., Boy-Marcotte, E., Damak, F., Jacquet, M.: Science, 248, (1990) 43) Wolf mar, A., Macara, I.: Science, 248, (1990) 44) Downward, J., Riehl, R., Wu, L., Weinberg, R. A.: Proc. Natl. Acad. Sci. USA, 87, 5998-

12 6002 (1990) 45) Yamamoto, T., Kaibuchi, K., Mizuno, T., Hi royoshi,m., Shirataki, H., Takai, Y.: J. Biol. Chem., 265, (1990) 46) Kamata, T., Feramisco, J.: Nature, 310, (1984) 47) Satoh, F., Endo, M., Nakafuku, M., Akiyama, T., Yamamoto, T., Kaziro, Y.: Proc. Natl. Acad. Sci. USA, 87, (1990) 48) Downward, J., Graves, J. D., Warne, P. H., Ray ter,s., Cantrell, D. A.: Nature, 346, ) Molly, C. J., Bottaro, D. P., Fleming, J. P., Mar shall,m. S., Gibbs, J. B., Aaronson, S. A.: Nature, 342, (1989) 50) Ellis, C., Moran, M., McCormick, F., Pawson, T.: Nature, 343, (1990) 51) Kaplan, D. R., Morrison, D. K., Wong, G., Mc Cormick,F., Williams, L. T.: Cell, 61, (1990) 52) Burgoyne, R. D.: TIBS, 14, (1989) 53) Chardin, P., Boquet, P., Madaule, P., Popoff, M. R., Rubin, E. J., Gill, D. M.: EMBO J., 8, (1989) 54) Paterson, H. F., Self, A. J., Garrett, M. D., Just, I., Aktories, K., Hall, A.: J. Cell. Biol., 111, (1990) 55) Hall, A.: Nature, 349, (1990) 56) Kitayama, H., Sugimoto, Y., Matsuzaki, T., Ikawa, Y., Noda, M.: Cell, 56, (1989) 57) Kikuchi, A., Sasaki, T., Araki, S., Hata, Y., Takai, Y.: J. Biol. Chem., 264, (1989) 58) Quinn, M. T., Parkos, C. A., Walker, L., Or kin,s. H., Dinauer, M. C., Jesaitis, A. J.: Na ture,342, (1989) 59) Hall, A.: Science, 249, (1990) 60) Lowe, D. G., Capon, D. J., Dehart, E., Sakagu chi,a. Y., Naylor, S. L.,. Goeddel, D. V.: Cell, 48, (1987) 61) Pizon, V., Chardin, P., Lerosey, I., Olofsson, B., Tavitian, A.: Oncogene, 3, (1988) 62) Madaule, P., Axel, R.: Cell, 41, (1985) 63) Touchot, N., Chardin, P., Tavitian, A.: Proc. Natl. Acad. Sci. USA, 84, (1987) 64) McCormick, F.: in Oncogenes and the Mo lecularorigins of Cancer, pp , Cold Spring Harbor Laboratory Press, New York (1990) 65) Lowe, D. G., Capon, D. J., Dehvart, E., Sakagu chi,a. Y., Naylor, S. L., Goeddel, D. V.: Cell, 48, (1987) 66) Chardin, P., Tavitian, A.: EMBO J., 5, (1986) 67) Touchot, N., Chardin, P., Tavitian, A.: Proc. Natl. Acad. Sci. USA, 84, (1987)

Database Center for Life Science Online Service School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferati

Database Center for Life Science Online Service School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferati School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferation and Activation Mechanism of GTP Binding Proteins by the Enzyme 3) Nishizuka, Y.: Nature,

More information

Spatio-temporal regulation of ERK1/2 MAP kinase 20) Murphy, L. 0., MacKeigan, J. P., Blenis, J.: Mol. Cell. Biol., 24, 144-153 (2004) 21) Harada, T., Morooka, T., Ogawa, S., Nishida, E.: Nature Cell

More information

Various function and toxicity of iron Key words 1) Hentze, M. W. et al: Cell, 117, 285-297 (2004) 2) Ganz, T.: Blood, 102, 783-788 (2003) 3) Nemeth, E. et al.: Science, 306, 2090-2093 (2004) 4) Hentze,

More information

1) van Meer, G., Op den Kamp, J. A.: J. Cell. Biochem., 19, 193-2040982) 2) Gaffet, P., Bettache, N., Bienvenue, A.: Biochemistry, 34, 6762-6769(1995) 3) Sims, P. J., Wiedmer, T.: Thromb. Haemost., 86,

More information

The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Database Center for Life Science Online Service Key words Shigey

The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Database Center for Life Science Online Service Key words Shigey The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Key words Shigeyuki Kawai, Chikako Fukuda, Kousaku Murata E-mail : kawais@kais.kyoto-u.ac.jp, chikakko@kais.kyotou.ac.jp,

More information

Correlation between molecular evolution of P450s and evolution of plant secondary metabolism Masaharu Mizutani E-mail : mizutani@scl.kyoto-u.ac.jp URL : http://biofun.kuicr.kyoto-u.ac.jp/index-j.html 13)

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 1) Bittner, J. J.: Science, 84, 162 (1936) 13) Michalides, R., van Ooyen, A., Nusse, R.: Curr. Top. Microbiol. Immunol., 106, 57-74 (1983) 2 z Yamamoto, K. R.: Ann. Rev. Genn., 19, 209-252 (1985) 3) Evans,

More information

Review Fumio Imamoto1, Takefumi Sone1, Kazuhide Yahata1, Yukari Sasaki1, Masatoshi Takagi2, Kazuhiro Maeshima2, Naoko 25) Dong, W. K. et al.: Gene, 91, 217-223 (1990) 26) Masatsugu, T. et al.:

More information

Minamiooya, Machida, Tokyo 194, Japan] RNA World, A Key Step in the Origin of Life : Inspection from the View Point of Biological Evolution 1) Crick, F. H. C.: Sym. Soc. Exp. Biol., 12, 548-555

More information

Database Center for Life Science Online Service archlaboratories, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki-shi, Kanagawa 213, Japan] Developmental Genetics of Caenorhabditis elegans Database Center for

More information

Kazumitsu Ueda, [Department of Applied Life Science, Kyoto University Graduate School of Agriculture, Kitashirakawa, Sakyo-ku, Kyoto 606-01, Japan] Molecular Mechanisms for Drug Transport by MDR1/P-glycoprotein

More information

64) M.L. Gefter, R.L. Russell: J. Mol. Biol., 39, 145 (1969) 65) F. Harada, F. Kimura and S. Nishimura: Biochim. Biophys. Acta., 182, 590 (1969) 65a) F.H.C. Crick: J. Mol, Biol., 19, 548 (1966); M. Nirenberg

More information

Database Center for Life Science Online Service Discovery, analysis and chemical mechanism of protein splicing

Database Center for Life Science Online Service Discovery, analysis and chemical mechanism of protein splicing Discovery, analysis and chemical mechanism of protein splicing VMA1 VMA1 2) Anraku, Y.: Genes to Cells, 2, 359-367 (1997) 3) Perler, F. B.: Cell, 92,1-4 (1998) 4) Perler, F. B.: Trends Biochem.

More information

表1.eps

表1.eps Vol.1 C ontents 1 2 cell-free EMBO J Proc. Natl. Acad. Sci. USA NatureEMBO J 3 RNA NatureEMBO J Nature EMBO J 4 5 HCV HCV HCV HCV RNA HCV in situ 6 7 8 Nat Struct Mol Biol J Biol Chem Nat Commun J Virol

More information

Database Center for Life Science Online Service Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara,

Database Center for Life Science Online Service Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara, Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara, E-mail : horikosh@iam.u-tokyo.ac.jp http://www.iam.u-tokyo.ac.jp/homasami/ 1) Jacob, F., Monod, J. : J. Mol. Biol., 3, 318-356 (1961) 2) Ptashne,

More information

Florigen in rice Key words Shojiro Tamaki, Ko Shimamoto E-mail : s-tamaki@bs.naist.jp, simamoto@bs.naist.jp URL : http://bsw3.naist.jp/simamoto/simaoto.html 1) Thomas, B., Vince-prue, D.: Photoperiodism

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 1) Epps, H. M., Gale, E. F.: Biochem. J., 36, 619-623 (1942) 2) Monod, J.: Recherches sur la croissance des cultures bacteriennes, Ph. D. thesis. Her mann,paris (1942) 3) Magasanik, B.: Cold Spring Harbor

More information

drug development Toshimi Michigami, E-mail : michigami@mch.pref.osaka.jp Keiichi Ozono, E-mail : keioz@ped.med.osaka-u.ac.jp The progress in the research on vitamin D 1) McCollum, E. V. et al.:

More information

10中西_他.indd

10中西_他.indd Streptomyces mobaraensis N N N Sm b Sm N N Sm Sm Sm ' ' Sm Sm ak K k K bk k K Sm Sm a b S. mobaraensis a b a b Sm b b bb b b Sm Sm S. lividans ab Sm ab Sm ab ab ab ab SmSm S. lividansab S. lividans ab

More information

D., Nicola, N. A., Hilton, D. J.: Nature, 387, 917-921 (1997) 12) Alexander, W. S. : Nat. Rev. Immunol., 2,410-416 (2002) 13) Chung, C. D., Liao, J., Liu, B., Rao, X., Jay, P., Berta, P., Shuai, K. : Science,

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 2) Shin, S. I., Fredman, V. H., Risser, P., Pol lack,r.: Proc. Natl. Acad. Sci. USA, 72, 4435-4439 (1975) 3) Marquardt, H., Todaro, G. J.: J. Biol. Chem., 256, 6859-6865 (1981) 4) Dicker, P., Pohjanpelto,

More information

Database Center for Life Science Online Service Structure and function of nitric oxide synthases

Database Center for Life Science Online Service Structure and function of nitric oxide synthases Structure and function of nitric oxide synthases 3) Furchgott, R. F., Zawadzki, J. V. : Nature, 288,373-376 (1980) 4) Palmer, R. M., Ferrige, A. G., Moncada, S.: Nature, 327,524-5260987) 5) Alderton,

More information

酵母 にお ける性 フ ェ ロモ ンの シ グナ ル 伝達 多 細 胞 生 物 に お け る 細胞 の機 能 は,ホ 土 屋 英 子 1 福 井 作 蔵 1,2 ル モ ンな ど 様 々な 情 報 分 子 に よ る 調 節 を 受 け て い る.細 胞 表 面 の レセ プ タ ー で 受 容 され た 外 来 情 報 は 細胞 膜 を介 し,ご え られ,細 宮 川 都 吉 1 く限 られ

More information

Short Review E-mail : kuwata@cc.gifu-u.ac.jp Structural medicine and structure-based drug design for prion diseases 2) Anfinsen, C. B.: Harvey Lect., 61, 95-116 (1967) 3) Carrel, R. W., Lomas, D. A.

More information

Bio-No.57/3....

Bio-No.57/3.... 2004. MAR. 3No.57 http://www.wako-chem.co.jp C O N T E N T S 2 Wako Bio Window No.57 MAR.2004 l l l l wako wako l l mmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmm Wako Bio Window No.57 MAR.2004 3 4 Wako Bio Window

More information

Database Center for Life Science Online Service Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sap

Database Center for Life Science Online Service Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sap Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060, Japan] Molecular Basis of Triplet Repeat Diseases : Genetic Instabillity and Unusual DNA

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service SMN (Survival

More information

Database Center for Life Science Online Service Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal

Database Center for Life Science Online Service Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal transduction Needleman, R., Lanyi, J. K. : Science, 269,73-75 (1995) 3) Bogomolni, R. A., Stoeckenius,

More information

Stress-responsive MAP kinases 15) Lu, H. T., Yang, D. D., Wysk, M., Gatti, E., Mellman, I., Davis, R. J., Flavell, R. A. : EMBO J., 18,1845-1857 (1999) 16) Lu, B., Yu, H., Chow, C., Li, B., Zheng,

More information

Teru Ogura, Tomoko Yamada-Inagawa, E-mail : ogura@gpo.kumamotou.ac.jp AAA family ATPases : ring-shaped chaperones which catalyze energy-dependent conformational changes of proteins 29) Braun, S.,

More information

Database Center for Life Science Online Service Chiharu Ueguchi, Molecular mechanism and biological function of t

Database Center for Life Science Online Service Chiharu Ueguchi,   Molecular mechanism and biological function of t Chiharu Ueguchi, E-mail : cueguchi@agr.nagoya-u.ac.jp Molecular mechanism and biological function of the cytokinin signal tansduction pathway 1) Miller, C. 0., Skoog, F., von Saltza, M. H., Strong,

More information

1) Y. Hatefi: Annu. Rev. Biochem., 54, 1015 (1985). 2) H. Weiss, T. Friedrich, G. Hofhaus & D. Preis: Eur. 4) M. Yamaguchi & Y. Hatefi: Biochemistry, 32, 1935 (1993). 5) K. Leonard, H. Haiker & H. Weiss:

More information

.i...j...[.X8-2

.i...j...[.X8-2 Vol. 8 No.2 Nov. 2007 1 2 4 12 20 37 45 54 56 62 1 2 3 4 5 7 6 8 9 10 11 13 12 15 14 17 16 19 18 21 20 Hatena 23 22 Oidiodendron Oidiodendron 25 24 Monosiga ovata Monosiga 27 26 Toxoplasma gondii 29 28

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 図8SINEの SINEと3'末 親 と な って い るLINEの 系 統 関係 端 を共 有 して い るLINEは 赤 色 で 示 す, 報 告 さ れ て い るす べ て のLINEは11の ら れ る.そ れ ぞ れ のLINEの グル ー プ に分 け あ い だ にお い て 水 平 的 な交 流 が な い と仮 定 す る と,こ の11に 分 け られ る こ のLINE え

More information

Makoto Onoda, Department of Anatomy and Cell Biology, Georgetown University School of Medicine, 3900 Reservoir Road, N. W., Washington, D. C. 20007, USA Regulation Mechanism of Spermatogenesis : Cell-to-cell

More information

1) Murphy, T.H., Miyamoto, M., Sastre, A., Schnaar, R.L., Coyle, J.T.: Neuron, 2, 1547-1558 (1989) 2) Pellegrini-Giampietro, D.E., Cherici, G., Ale siani,m., Carla, V., Moroni, F.: J. Neuro science,10,

More information

Kazumitsu Ueda, E-mail : uedak@kais.kyoto-u.ac.jp http : //cseika-1, kais.kyoto-u.ac.j p Molecular mechanism of multidrug transporter MDR I : ABC in host-defense machinery 32P-ATP 1) Chen, C., Chin,

More information

Database Center for Life Science Online Service 35) [Laboratory of Hepatitis Viruses II, Department of Enteroviruses, National Institute of Health, Ka

Database Center for Life Science Online Service 35) [Laboratory of Hepatitis Viruses II, Department of Enteroviruses, National Institute of Health, Ka 35) [Laboratory of Hepatitis Viruses II, Department of Enteroviruses, National Institute of Health, Kamiosaki, Shinagawa-ku, Tokyo 141, Japan] Hepatitis C Virus 1) Choo, Q.-L., Kuo, G., Weiner,

More information

Review Database Center for Life Science Online Service Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge

Review Database Center for Life Science Online Service Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge Review Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge E-mail : m.mishima @gurdon.cam.ac.uk http://www.gurdon.cam.ac.uk/groups/mishima.html Cytokinesis :

More information

tary adenylate cyclase activating polypeptide ; PA-

tary adenylate cyclase activating polypeptide ; PA- Conformation of a peptide ligand bound to its G-protein coupled receptor and its implication for ligand transportation tary adenylate cyclase activating polypeptide ; PA- molecular biology (ed. Rich,

More information

Novel chemical mediators in the resolution of inflammation Charles N. Serhan Key words E-mail : marita@nih.go.jp Charles N. Serhan Brigham & Women's Hospital/Harvard Medical School 1) Serhan, C. N.,

More information

4) H. Takayama et al.: J. Med. Chem., 45, 1949 (2002). 5) H. Takayama et al.: J. Am. Chem. Soc., 112, 8635 (2000). 6) H. Takayama et al.: Tetrahedron Lett., 42, 2995 (2001). 9) M. Kitajima et al: Chem.

More information

2007050781......_.L.O...z.W

2007050781......_.L.O...z.W a s d f g a s d f g h j k l 0 in vitro in vivo in vitro in vivo in vivo in vivo in vitro Metabolism Metabolism Endocr Endocr Endocrinol Ann NYA cad Sci J clin Endocr Metab

More information

Database Center for Life Science Online Service Signal transduction of growth factor mediated by heparin heparan sulfate

Database Center for Life Science Online Service Signal transduction of growth factor mediated by heparin heparan sulfate Signal transduction of growth factor mediated by heparin heparan sulfate 1) Zhu. X.. Komiya, H., Chirino, A.. Faham. S.. Fox, G. M., Arakawa, T., Hsu, B.T., Rees, D. C.: Science. 251, 90-93 (1991)

More information

2

2 1999 No. 5 CHAPERONE NEWSLETTER CONTENTS 2 3 4 JEM JEM JEM, SEC, SCJ JEM JEM SCJ jem, scj 5 in vitro S. cerevisiae 6 K 7 in vitro Cell Mol. Cell in vitro 8 9 E. coli E. coli 10 in vitro ssc - b 11 in vivo

More information

ü β 93

ü β 93 Amyloid Fibril Formation and Protein Science Yuji GOTO Institute for Protein Research, Osaka University E-mail: ygoto@protein.osaka-u.ac.jp Abstract: Amyloid fibrils have been a critical subject in recent

More information

untitled

untitled Fig.1 t O O N,N p n J J J J J t J J J J J J J J J J J t t J J J J J J J J J p Fig.2 p t Fig.3 Fig.4 synanti p Table1 Table2t Table2 synanti antisyn synanti synanti Fig.5 syn anti anti Fig.6 Table3 Table4

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 20) Unwin, N.: Nature, 373, 37-43 (1995) 22) Berridge, M.: Nature, 361, 315-325 (1993) 1) Johnson, L. N., Cell, 85, 149-158 2) Hanks, S. K., (1995) Noble, M. E. M Owen, (1996) Hunter, T. : FASEB J., D.

More information

[Nippon Nogeikagaku Kaishi

[Nippon Nogeikagaku Kaishi [ Nippon Nageikagaku Kaishi Vol. 72, No. 11, pp. 1333 `1344, 1998 l Key words: methylotrophic yeast; gene expres sion; C1-metabolism; peroxisome Cellular Functions of the Methylotrophic Yeast: Their Molecular

More information

Vol.53 No. 11 (2008) 1327

Vol.53 No. 11 (2008) 1327 Molecules that regulate morphology of the plasma membrane Shiro Suetsugu, Kazunori Takano E-mail : suetsugu@iam.u-tokyo.ac.jp 1326 Vol.53 No. 11 (2008) Vol.53 No. 11 (2008) 1327 1328 Vol.53 No. 11 (2008)

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service アデノウイルスベクターの改良と応用 7 ン トネ ガ テ ィ ブ を用 い てRel NF-κBの シグナル の不 活 化 を 試 み た そ の 結 果 IκBの ド ミナ ン トネ ガ テ ィ ブ を ニ ワ ト リ胚 肢 芽 に 接 種 した 群 で は 発 現 率 は低 い もの の 四 肢 の 形 成 阻 害 が 認 め られ この 結 果 は頂 堤 AER)を 除 去 した も の の表

More information

E-mail : tmatsumo@house.rbc.kyoto-u.ac.jp htm Spindle checkpoint : Cell cycle regulation by a signal emitted from kinetochores http://www.rbc.kyoto-u.ac.jp/radiation_system/m-index. 19) Yao, X., Abrieu,

More information

Database Center for Life Science Online Service (http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*,

Database Center for Life Science Online Service (http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*, (http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*, E mail : takaabe@mail.cc.tohoku.ac.jp Taro Tokui, Molecular identification of organic anion transporter

More information

1...z04/08/.e2

1...z04/08/.e2 August 2004 29 α α 30 Functional Glycomics News Letter No.4 α α August, 2004 31 β ü β α β α 32 Functional Glycomics News Letter No.4 α β August, 2004 33 34 Functional Glycomics News Letter No.4 α β ü August,

More information

Review Column 1) Extavour, C. G., Akam, M. : Development, 130, 5869-5884 (2003) 2) Saitou, M. et al.: Philos. Trans. R. Soc. Lond. B. Biol. Sci., 358,1363-1370(2003) 3) Eddy, E. M. : Int. Rev.

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 10) Shinagawa, H., Kato, T., Ise, T., Makino, K., Acad. Sci. USA, 82, 4336-4340 (1985) Sci. USA, 85, 1811-1815 (1988) 19 zwoodgate, R., Rajagopalan, M., Lu, C., Echols, H.: Proc. Natl. Acad. Sci. USA,

More information

Generation of neural cells from embryonic stem cells Database Center for Life Science Online Service Takuya Yohei Okada Takahito Hideyuki Shimazaki Yo

Generation of neural cells from embryonic stem cells Database Center for Life Science Online Service Takuya Yohei Okada Takahito Hideyuki Shimazaki Yo Generation of neural cells from embryonic stem cells Takuya Yohei Okada Takahito Hideyuki Shimazaki Yoshizaki* Okano McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence

More information

(Sinorhizobium melitoti )

(Sinorhizobium melitoti ) ID ID INDE- TERMINATE (ID) /JST CREST E-mail : masayosicbiol. s.u-tokyo.ac.j p Systemic regulatory system sustaining symbiosis and organ development in legume (Sinorhizobium melitoti ) astray sunn nts

More information

11) Zarnegar, R., Michalopoulos, G.: Cancer Res.,49, 3314-3320 (1989) 1) Moolten, C. D. G., Bucher, N. L. R.: Science, 158, 272-274 (1967) 2) Berry, M. N., Friend, D. S.: J. Cell Biol., 43, 506-520 (1969)

More information

Biology of spermatogenesis and spermatozoa in mammals. Biophys. Biochem. Cytol. Arch. Biochem. Biophys. Anat. Rec. Biol. Reprod. Mol. Hum. Reprod. Biol. Reprod. Reprod. Biol. Endocrinol. Aust. J. Zool.

More information

本文/YA7261E

本文/YA7261E J. Cell Biol.,,. Segev, N.Curr. Opin. Cell Biol.,,. Lafont, F., Lecat, S., Verkade, P., & Simons, K.J. Cell Biol.,,. Mostov, K.E., Verges, M., & Altschuler, Y.Curr. Opin. Cell Biol.,,. Sato, T., Mushiake,

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 56 蛋 白質 核酸 酵素 Vol.42 No.11(1997) して い る ことが明 らか にな っ た 先 に も述 べ た と お り, OSH1とKN1は1次 構造お よび胚発 生後 の発現様 式 の特 徴が よ く似 ていることか ら,オ ル ソロガス遺 伝 子で あ る と考 え られ るが,胚 発 生初 期 にお い て は,こ の よ うに両 者 の発 現 に違 いが み られた

More information

Short Review Database Center for Life Science Online Service Shou Takashima, Masafumi Tsujimoto, Shuichi Tsuji, Fun

Short Review Database Center for Life Science Online Service Shou Takashima, Masafumi Tsujimoto,   Shuichi Tsuji, Fun Short Review Shou Takashima, Masafumi Tsujimoto, E-mail : staka@postman.riken.go.jp Shuichi Tsuji, Functional analysis of sialylglycoconjugates by sialyltransferase deficient mice GINAcT : N-acetylglucosaminyltransferase,

More information

本文/YA9255F

本文/YA9255F pp. ATP ε ATP ATP ATP ε Bacillus PS ATP ATP H H µ H ATP ATP ADP µ H ATP FoF -ATP FoF -ATP µ H H ADP ATP H Na On the regulatory role of the epsilon subunit in ATP synthase Yasuyuki Kato-Yamada Department

More information

Review Yoshihiro Yoneda, Soo Jae Lee, E-mail : yyoneda@anat3.med.osaka-u. ac.jp http: //www.anat3.med.osaka-u.ac.jp/ Molecular basis of importin g revealed by crystal structures 2) Yoneda, Y. : Genes

More information

Database Center for Life Science Online Service Vol.48 No.16 (2003)

Database Center for Life Science Online Service Vol.48 No.16 (2003) Database Center for Life Science Online Service Key words Kikuya Kato, E-mail : kkato@bs.aist-nara. ac.jp http://love2.aist-nara.ac.jp Shin Ishii, E-mail : ishii@is.aist-nara.ac.jp http://hawaii.aist-nara.

More information

(1) C A. Coulson: Valence, Oxford-Clarendon Press, 1952. (2) L Pauling: The Nature of the Chemical Bond, Cornell Univ Press, 1940, 1960 (3) G. C Pimentel, A L McClellan: The Hydrogen Bond, W. H. Freeman

More information

Mechanism of Action of Electrogenic (Na, K)-ATPase Plasma membrane (Na, K)-ATPase transports 3 Na + out of and 2 K+ into the cell, and thus the pump i

Mechanism of Action of Electrogenic (Na, K)-ATPase Plasma membrane (Na, K)-ATPase transports 3 Na + out of and 2 K+ into the cell, and thus the pump i Mechanism of Action of Electrogenic (Na, K)-ATPase Plasma membrane (Na, K)-ATPase transports 3 Na + out of and 2 K+ into the cell, and thus the pump is electrogenic. This review describes experiments on

More information

Database Center for Life Science Online Service Enzyme Research, The University of Tokushima, Kuramoto-cho, Tokushima 770, Japan] Clathrin : Its Struc

Database Center for Life Science Online Service Enzyme Research, The University of Tokushima, Kuramoto-cho, Tokushima 770, Japan] Clathrin : Its Struc Enzyme Research, The University of Tokushima, Kuramoto-cho, Tokushima 770, Japan] Clathrin : Its Structure and Role in Intracellular Transport 3) c ã T : Œ» 㻚w, J Š 10, 100-123 (1987) 4 zpfeffer,

More information

Database Center for Life Science Online Service Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie

Database Center for Life Science Online Service Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie Universitat Freiburg Zentrum fur Molekulare Biologie (ZMBH) Universitat Heidelberg E-mail : bukau@zmbh.uni-heidelberg.de

More information

寄稿論文 高い発ガン活性を示す鉄キレートお構造特性 | 東京化成工業

寄稿論文 高い発ガン活性を示す鉄キレートお構造特性 | 東京化成工業 NTBI = nontransferrin-bound iron NTBI DNA H DNA 2 NTBI NTBI NTBI NTBI NTBI NTBI (nta) (nta) (nta) NTBI (nta) (nta) NTBI (nta)ntbi Fe-(nta) (nta) N(CH 2 CH) 3 HCCH 2 NHCH 2 CH 2 NHCH 2 CH (HCCH 2 ) 2 NH

More information

2) Pytela, R., Pierschbacher, M. D., Ruoslahti, E.: Cell, 40, 191-198 (1985) 3 z Thunberg, L., Backstrom, G., Lindahl, U.: Carbohydr. Res., 100, 393-410 (1982) 4) Petitou, M.: Nelle. Rev. Fr. Hematol.,

More information

[Department of Pediatrics, Gifu University School Clinical. Pathological and Biochemical Abnormality in peroxisomal Disorders 1) Goldfischer, S., Moore, C. L., Johnson, A. B., Spiro, A. J., Valsamis,

More information

肺癌第50巻第4号

肺癌第50巻第4号 1 Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan; 2 Department of Thoracic Surgery, Aichi Cancer Center, Japan;

More information

たんぱく3000web.indd

たんぱく3000web.indd 1 2 4 5 3000 6 8 3000 10 10 11 11 12 12 13 13 14 18 19 20 21 Atg 22 23 24 21 X 143000 3000 19 3000 20 25 X 26 27 28 1 20 DNA mrna DNA RNA mrna 3000 DNAmRNARNA SPring-8X Artsimovitch, I. et al., Cell 117,

More information

本文/YA9121A

本文/YA9121A pp. CD CDHA HA CD HABD NMR HABD C HA ordered O -state HA partially disordered PD -state PD-state CD HA HA CD CD A Two-state equilibrium of hyaluronan-binding domain is crucial for CD -mediated cell rolling

More information

Tomohiro Terada, Ken-ichi Inui, Peptide transporter family situ 1) Matthews, D.M. : Physiol. Rev., 55, 537-608(1975) 2) Ganapathy, V.. Leibach, F.H.: Am. J. Physiol. Gastro intest. Liver Physiol.,

More information

本文/YA4278I

本文/YA4278I pp. D- D-DAO DAO D- D- D- D- o- DAO-D- D-DAO DAO Hans Krebs FAD X DAO DAO DAO D- Structure and reaction mechanism of D-amino acid oxidase Yasuzo Nishina School of Health Sciences, Kumamoto University,

More information

Differentiation and search for palatability-factors of world-wide rice grains by PCR method Sumiko NAKAMURA, Hiroshi OKADOME, Koh-ichi YOZA, Kazutomo

Differentiation and search for palatability-factors of world-wide rice grains by PCR method Sumiko NAKAMURA, Hiroshi OKADOME, Koh-ichi YOZA, Kazutomo Differentiation and search for palatability-factors of world-wide rice grains by PCR method Sumiko NAKAMURA, Hiroshi OKADOME, Koh-ichi YOZA, Kazutomo HARAGUCHI, Tomoya OKUNISHI, Keitaro SUZUKI, Hikaru

More information

Short Review Hidenori Takagi, Fumio Takaiwa, E-mail : takaiwa@nias.affrc.go.jp 13) Hirahara, K. et al. : J. Allergy Clin. Immunol., 102, 961-967 (1998) 14) Takagi, H. et al.: Proc. Natl. Acad. Sci.

More information

Molecular bases for plant circadian clock and flowering : How does the quintet tell the time? Cell, 101, 319-329(2000) 8) Schultz, T. F., Kiyosue, T., Yanovsky, M., Wada, M., Kay, S. 9) A. : Plant

More information

VOL33NO.3/2010 A B A B p-erk1/2 Time (min) 0 1 2 5 10 15 30 60 90 120 Erk1/2 Time (min) 0 1 2 5 10 15 30 60 90 120 p-vasp VASP C D enos/gapdh x-fold vs sham 2.0 1.5 1.0 0.5 * 0 ANP (-) (+) (-)

More information

Undulator.dvi

Undulator.dvi X X 1 1 2 Free Electron Laser: FEL 2.1 2 2 3 SACLA 4 SACLA [1]-[6] [7] 1: S N λ [9] XFEL OHO 13 X [8] 2 2.1 2(a) (c) z y y (a) S N 90 λ u 4 [10, 11] Halbach (b) 2: (a) (b) (c) (c) 1 2 [11] B y = n=1 B

More information

色覚(初組4).pm

色覚(初組4).pm 733 3 1 520 1 8 4 0.2500 1 30012 1 AB 3 22 3 1 2 http://www.nig.ac.jp/labs/devgen/mou.html 734 1.1 360nm 830nm 380nm 780nm 540nm 580nm 660nm 540nm 660nm Log relative corneal sensitivity 0 1 2 400 500 600

More information

.J.[.v/01..

.J.[.v/01.. 1 J.L. Tan, et al., Proc. Nat l. Acad. Sci. U.S.A. 100, 42003Christopher S. Chen, The Johns Hopkins University 11 12 13 2 14 Box 11 Box 12 11 4 1 14 15 7 6 50 Å 2 0.2 µm 5 25 nm 3 1 4 35Å 10 µm 0.5 µm

More information

1) Ogawa, H., Lazarus, G. S., Hopsu-Havu, K.: The Biological Role of Proteinases and their Inhibitors in Skin, Univ. Tokyo Press (1985) 2) Sottrup-Jensen, L., Stepanik, T. M., Kristen sen,t., Wierzbicki,

More information

植 物 葉 にお け る 光 呼 吸 窒 素 循 環 系 山谷知行 光 合 成 で 同 化 した 炭 素 の-割 以 上 も炭 酸 ガ ス と して 失 う,大 変 不 思 議 で複 雑 な 光 呼 吸 系 が 植 物 葉 には あ る.炭 酸 ガ ス と同 じ速 度 で ア ンモ ニ ウ ム イオ ン も放 出 され て い る こ とが1978年 に 発 見 され た が,ア ン モ ニ ウ ム

More information

図1 A:融 試 験 管 内 受 精 と胚 様 体 発 育 お よび 植 物 体 再 生(ト ウ モ ロ コ シ) 合 前 の卵 細 胞(E)と 精 細 胞(S).バ ー=50μm, B:第1回 の 分 裂(融 合42時 間 後).バ ー=50μm, C:多 細 胞体(5日 後).バ ー=100μm, D:分 極 した 多 細 胞 体.一 方 の 極 に 細 胞 層 が,も う一 方 に液 胞 の

More information

本文/YA9056H

本文/YA9056H Davis, R.J., D Cruz, C.M., Lovell, M.A., Biegel, J.A., & Barr, F.G. Cancer Res.,,. Nakae,J.,Oki,M.,&Cao,Y. FEBS Lett.,,. Kodama, S., Koike, C., Negishi, M., & Yamamoto, Y. Mol. Cell Biol.,,. Matsuzaki,

More information

/‚“1/ŒxŒ{‚×›î’æ’¶

/‚“1/ŒxŒ{‚×›î’æ’¶ 60 1 pp.3-8 2010 1. H1N1 1) 2) 3) 4) ERATO 2009 H1N1 21 H1N1 HA PB2 2009 3 Pandemic H1N1 2009 WHO 6 11 21 2009 11 2010 4 21 H1N1 H1N1 2009 4 15 CDC 108-8639 4-6-1 TEL: 03-5449-5281 FAX: 03-5449-5408 E-mail:

More information

会誌71

会誌71 ATP * ATP γ γ 2 ATPC1 ATPC2ATPC2 ATPC2 ATPC1 ATP ATP 1. ATP ATP ATP ATP ATP F o F1 2 1) 1 ATP Trx γ ATP CFoCF1 ATP γ 2 Cys 2) 2 γ γ 3,4) ATP -γ 2 ATPC1 ATPC2 At4G04640, At1G15700 73 20 5) ATPC2 6) ATPC2

More information

10.02EWE51号本文

10.02EWE51号本文 51 2010 Mar. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

More information

607_h1h4_0215.indd

607_h1h4_0215.indd 3 2016 Mar. No.607 http://www.saitama-ctv-kyosai.net 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17

More information

研究室ガイダンス(H29)福山研v2.pdf

研究室ガイダンス(H29)福山研v2.pdf J.M. Kosterlitz and D.J. Thouless, Phys. 5, L124 (1972); ibid. 6, 1181 (1973) David J. Thouless J. Michael Kosterlitz + ρ T s KT D.J. Bishop and J.D. Reppy, PRL 40, 1727 (1978) ( ) = 2k B m2 T KT π 2 T

More information

宿 主 特 異 性 を決 定 す る た め に非 常 に大 き な 役 割 を も った 割 を 演 じ る こ と に な る.ま 物 質 で あ る こ とは 間 違 い な い.ま た,Nod る菌 体 外 多 糖 の生 成 が菌 の 感 染 に 関与 して い る こ と も知 factorは マ メ科 植 物 根 細 胞 の 根 粒 形成 に 関 す る 遺 伝 子(nodulin gene)を

More information

本文/AY380J

本文/AY380J MHC-II II MHC-II MHC- II CD T T TCR T T MHC-II MHC-II T MHC-II MHC-II MHC-II MHC-II Ii Ii-MHC-II MHC-II antigen processing compartment MIIC Regulation of cell surface expression of MHC-II in dendritic

More information

量子情報科学−情報科学の物理限界への挑戦- 2018

量子情報科学−情報科学の物理限界への挑戦- 2018 1 http://qi.mp.es.osaka-u.ac.jp/main 2 0 5000 10000 15000 20000 25000 30000 35000 40000 1945 1947 1949 1951 1953 1955 1957 1959 1961 1963 1965 1967 1969 1971 1973 1975 1977 1979 1981 1983 1985 1987 1989

More information