A study on the inductive mechanism of ovulation with Clomiphene citrate. (especially, at movement in urinary excretion of luteinizing hormone.)

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1 A study on the inductive mechanism of ovulation with Clomiphene citrate. (especially, at movement in urinary excretion of luteinizing hormone.)

2 CHEMICAL STRACTURE OF CLOMIPHENE CITRATE AND RELATED COMPAUND

3

4 OF DOSE RESPONSE CURVE NIH-LH-S16

5

6 COMPLETE MENSTRUATION CYCLE

7 A PATIENT WITH AMENORRHEA 1st GRADE

8

9 Result of clomiphene citrate therapy for induction of ovulation. OVULATION DAY AFTER ADOMINSTRATION OF CLOMIPHENE CITRATE IN AMENORRHEA 1st GRADE

10 EFFECT OF CLOMIPHENE CITRETE ON A PATIENT EARLY OVULATION GROUP WITH AMENORRHEA Is. GRADE

11 EFFECT OF CLOMIPHENE CITRATE ON A PATIENT WITH AMENORRHEA 1st GRADE

12 LATE OVULATION GROUP

13 EFFECT OF CLOMIPHENE CITRATE ON A PATIENT WITH AMENORRHEA 1st GRADE

14

15 1) Albert, A.:J. Clin. Endocr., 21:1, ) Albert, A.:J. Clin. Endocr., 21:856, ) Alexandridis, D., Apostolakis, M., and Voigt, K. D.:Acta. Endocr., 29:537, ) Ashheim, B., Zondek, S.:Dtsch. med. Wshr., 52:343, ) Beck, P. and Kupperman, H. S.:Obstet and Gynec., 27:54, ) Bell, E. T. Mukerji, S. and Loraine, J. A.: J. Endocr., 28:321, ) Bradbury, J. T. Brown, E. S. and Brown, W. E.:Proc. Soc. exp. Biol., 71:228, ) Brown, J. B. and Loraine, J. A.:J. Endocr., 17:401, ) Brown, J. B.:Acta Endocr., 32:272, ) Charles, D. and Loraine, J. A.:Amer. J. Obstet. Gynec., 86:913, ) Charles, D. and Harkness, R. A.:Fertil. and Steril, 17:351, ) Coppola, J. A. and Perrine, J. W.:Endocrinology, 76:865, ) D'Amour, F. E.:Amer. J. Obstet. Gynec., 40:958, ) Frank, R. T. and Goldberger, M. A.:Proc. Soc. Exper. Biol., 32:1663, ) Fukushima, M. and Voryo, N.:J. Clin. Endocr., 24:205, ) Greenblatt, R. B. and Mahesh, V. B. et al.: Fertil and Steril, 16:310, ) Heller, E. J.:J. clin. Endocr., 1:813, ) Holtkamp, D. E. Greslin, J. G., et al.: Proc. Soc. exp. Biol., 105:197, ) Igarashi, M. and Matsumoto, S.:Amer. J. Obstet. Gynec., 96:120, ) Jones, G. E. S. and Dells, E.:J. Clin. Endocr., 9:743, ) Kase, N. and Olson, L. E.:Amer. J. Obstet. Gynec. 98:1037, ) Kato, J. Kobayashi, T. and Villee. C. A.: Endocrinology, 82:1049, ) Kistner, R. W. and Smith, O. W.:Surg. Forum., 10:725, ) Levin, L.:Endocrinology., 28:378, ) Loraine, J. A. and Brown, J. B.:J. Endocr., 18:71, ) Mayfield, J. D. and Ward, D. N.:Acta endocr., 51:557, ) McArthur, J. W. Worcester, J. et al.:j. Clin. Endocr., 18:1186, ) Mellinger, R. C. and Thompson, R. J.: Fertil and Steril, 17:94, ) Minden, R. L. and Butler, A. M.:J. biol. chem., 122:673, ) Parlow, A. F.:Fed. Proc., 17:402, ) Paulsen, C. A. and Herman, W.:Clin. Res., 11:85, ) Riley, G. M. and Evans, T. M.:Amer. J. Obstet. Gynec., 89:97, ) Rosemberg, E. and Keller, P. J. et al.: J. Clin. Endocr., 25:1262, ) Roy, S. and Mahesh, V. B. et al.:acta endocr., 47:645, ) Roy, S. and Greenblatt, R. B.:Fertil. and Steril., 16:310, ) Roy, S. and Greenblatt, R. B.:Acta. endocr., 47:669, ) Smith, O. W.:Amer. J. Obstet. Gynec., 94:440, ) Smith, O. W. and Schiller, S.:Amer. J. Obstet. Gynec., 45:15, 1943.

16 53) Tsuyuguchi, M.:Jap. Obstet. Gynec. Soc., 14:75, ) Tyler, E. T.:Int. J. Fertil., 5:429, ) Venning, E. H. and Brown, J. S. L.:Endocrinol., 21:711, 1937.

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