fiúàÕ53-3†E4_fiÁ‘W02_‚S.indd

Size: px
Start display at page:

Download "fiúàÕ53-3†E4_fiÁ‘W02_‚S.indd"

Transcription

1 Pathological Features of IgG4-related Disease 1) Division of Pathology, Kanazawa University Hospital 2) Department of Human Pathology, Kanazawa University Graduate School of Medicine NICHIDOKU-IHO Vol. 53 No (2008) Yoh Zen, M.D., Ph.D., 1) and Yasuni Nakanuma, M.D., Ph.D. 2) Summary IgG4-related diseases have been identified in a variety of organ systems. Irrespective of the organ of origin, IgG4-related disease is pathologically characterized by diffuse lymphoplasmacytic infiltration, irregular fibrosis, occasional eosinophil infiltration, and obliterative phlebitis. Immunostaining of IgG4 reveals diffuse infiltration of IgG4-positive plasma cells in each lesion. IgG4-related diseases can manifest diffuse infiltrative or localized nodular lesions in each organ. Idendified IgG4-related diseases can be summarized as follows: autoimmune pancreatitis, sclerosing cholangitis, hepatic inflammatory pseudotumor, chronic sclerosing sialadenitis, chronic sclerosing dacryoadenitis, interstitial pneumonia, pulmonary inflammatory pseudotumor, retroperitoneal fibrosis, and inflammatory abdominal aneurysm. In addition, they could occur at different sites or asynchronously in a patient. Clinico-radiologically, IgG4- related diseases sometimes pose difficulty in differentiating from true neoplasms. However, it is important to pathologically differentiate IgG4-related diseases from other autoimmune and/or lymphoproliferative disorders. This is because IgG4-related diseases may respond appropriately to steroid therapy with accurate diagnosis. IgG4 IgG4 IgG4 IgG4 IgG4 IgG4 IgG4 IgG4

2 EVG IgG4IgG IgG4 1 IgG4 2 IgG4 IgG4 3 IgG4 2 1 IgG4 2 IgG4 IgG4 2 2 IgG4 4 IgG4 IgG4 4 IgG4 IgG4 IgG4 1A B 1C 5 HE

3 EVG 1DIgG4 IgG4 1EF 6 7 IgG4 IgG4 IgG4 IgG4 IgG4 IgG4 IgG4 IgG4 IgG A 8 IgG4 IgG4 primary sclerosing cholangitispsc 9 PSC IgG4 PSC IgG4 PSC IgG4 PSC IgG4 3BD 3C IgG4 IgG4 PSC 7 IgG4 410 Kuttner 4AB IgG4 4C 4 Sjögren Sjögren Sjögren Sjögren IgG4 IgG4

4 Mikulicz Mikulicz MikuliczIgG4 11 Mikulicz

5 IgG4PSC

6 IgG4IgG4 IgG IgG IgG4 IgG4 14 IgG4 5A non-specific interstitial pneumonia NSIPpattern 5BC IgG4 5D IgG4 IgG IgG4 15 IgG4

7 IgG4IgG4

8 CT EVG IgG4 6ACIgG4 6D 6E IgG IgG4 IgG4

9 IgG4 IgG4 19 IgG4 heterogeneous fibrohistiocytic type plasma cell granulomalymphoplasmacytic type inflammatory myofibroblastic tumor IgG4 lymphoplasmacytic typeplasma cell granuloma IgG4 20 lymphoplasmacytic type plasma cell granuloma IgG4 2 IgG4 IgG4 IgG4 IgG4 21 IgG4 IgG4 IgG4 IgG4 retrospective IgG4 IgG4 22 IgG4 2 prospective study IgG4 22 7AC IgG4 IgG4 7DE IgG4 IgG4 periaortitis + 3 IgG4 3 IgG4 -related periaortitis 22 IgG4 23 IgG4 IgG4 IgG4 IgG4

10 IgGIgG4 IgG4 IgG4 17 IgG4 IgG4 IgG4

11 IgG4 7 IgG4 IgG4 Th2 T 24 IgG4 IgG Hamano H, Kawa S, Horiuchi A, et al: High serum IgG4 concentrations in patients with sclerosing pancreatitis. N Engl J Med : , Hamano H, Kawa S, Ochi Y, et al: Hydronephrosis associated with retroperitoneal fibrosis and sclerosing pancreatitis. Lancet : , Deshpande V, Chicano S, Finkelberg D, et al: Autoimmune pancreatitis: a systemic immune complex mediated disease. Am J Surg Pathol : , Kitagawa S, Zen Y, Harada K, et al: Abundant IgG4- positive plasma cell infiltration characterizes chronic sclerosing sialadenitis (Küttners tumor). Am J Surg Pathol : , Kawaguchi K, Koike M, Tsuruta K, et al: Lymphoplasmacytic sclerosing pancreatitis with cholangitis: a variant of primary sclerosing cholangitis extensively involving pancreas. Hum Pathol : , Kamisawa T, Funata N, Hayashi Y, et al: Close relationship between autoimmune pancreatitis and multifocal fibrosclerosis. Gut : , Zen Y, Harada K, Sasaki M, et al: IgG4-related sclerosing cholangitis with and without hepatic inflammatory pseudotumor, and sclerosing pancreatitis-associated sclerosing cholangitis: do they belong to a spectrum of sclerosing pancreatitis? Am J Surg Pathol : , Hamano H, Kawa S, Uehara T, et al: Immunoglobulin G4- related lymphoplasmacytic sclerosing cholangitis that mimics infiltrating hilar cholangiocarcinoma: part of a spectrum of autoimmune pancreatitis? Gastrointest Endosc : , Björnsson E, Chari ST, Smyrk TC, et al: Immunoglobulin G4 associated cholangitis: description of an emerging clinical entity based on review of the literature. Hepatology : , Takahira M, Kawano M, Zen Y, et al: IgG4-Related chronic sclerosing dacryoadenitis. Arch Ophthalmol : , Yamamoto M, Harada S, Ohara M, et al: Clinical and pathological differences between Mikuliczs disease and Sjögrens syndrome. Rheumatology (Oxford) : , Taniguchi T, Ko M, Seko S, et al: Interstitial pneumonia associated with autoimmune pancreatitis. Gut : 770, Takato H, Yasui M, Ichikawa Y, et al: Nonspecific interstitial pneumonia with abundant IgG4-positive cells infiltration, which was thought as pulmonary involvement of IgG4-related autoimmune disease. Intern Med : , Nieminen U, Koivisto T, Kahri A, et al: Sjögrens syndrome with chronic pancreatitis, sclerosing cholangitis, and pulmonary infiltrations. Am J Gastroenterol : , Zen Y, Kitagawa S, Minato H, et al: IgG4-positive plasma cells in inflammatory pseudotumor (plasma cell granuloma) of the lung. Hum Pathol : , Hamed G, Tsushima K, Yasuo M, et al: Inflammatory lesions of the lung, submandibular gland, bile duct and prostate in a patient with IgG4-associated multifocal systemic fibrosclerosis. Respirology : , Taniguchi T, Hamasaki A, Okamoto M: A case of suspected lymphocytic hypophysitis and organizing pneumonia during maintenance therapy for autoimmune pancreatitis associated with autoimmune thrombocytopenia. Endocr J : , Kobayashi H, Shimokawaji T, Kanoh S, et al: IgG4-positive pulmonary disease. J Thorac Imaging : , 2007

12 Zen Y, Kasahara Y, Horita K, et al: Inflammatory pseudotumor of the breast in a patient with a high serum IgG4 level: histologic similarity to sclerosing pancreatitis. Am J Surg Pathol : , Zen Y, Fujii T, Sato Y, et al: Pathological classification of hepatic inflammatory pseudotumor with respect to IgG4- related disease. Mod Pathol : , Zen Y, Sawazaki A, Miyayama S, et al: A case of retroperitoneal and mediastinal fibrosis exhibiting elevated levels of IgG4 in the absence of sclerosing pancreatitis (autoimmune pancreatitis). Hum Pathol : , Kasashima S, Zen Y, Kawashima A, et al: Inflammatory abdominal aortic aneurysm: close relationship to IgG4- related periaortitis. Am J Surg Pathol : , Matsumoto Y, Kasashima S, Kawashima A, et al: A case of multiple immunoglobulin G4-related periarteritis: a tumorous lesion of the coronary artery and abdominal aortic aneurysm. Hum Pathol : , Zen Y, Fujii T, Harada K, et al: Th2 and regulatory immune reactions are increased in immunoglobin G4-related sclerosing pancreatitis and cholangitis. Hepatology. : , 2007

fiúàÕ53-3†E4_fiÁ‘W04_−Šfic.indd

fiúàÕ53-3†E4_fiÁ‘W04_−Šfic.indd Imaging Diagnosis of Sclerosing Cholangitis Toshifumi Gabata, M.D., 1) Dai Inoue, M.D., 1) Osamu Matsui, M.D., 1) Hiroki Tatsu, M.D., 2) and Yasunari Fujinaga, M.D. 3) 1) Department of Radiology, Kanazawa

More information

1) Delbet P: Retrocissement du choledoque. Cholecysto-duodenostomie. Bull Mem Soc Nat Chir 50: 1144-1146, 1924 2) Wiesner RH, LaRusso NF: Clinicopathologic Features of the Syndrome of Primary Sclerosing

More information

49-4 ™ñ„¾ Œ]„”†i4†j

49-4 ™ñ„¾ Œ]„”†i4†j Current Topics in Diagnostic Imaging of the Pediatric Neck Eiji Oguma, M.D. Department of Radiology, Saitama Children s Medical Center NICHIDOKU-IHO Vol. 49 No. 4 61 83 (2004) Summary This article focuses

More information

Medical Journal of Aizawa Hospital Medical Journal of Aizawa Hospital Vol. 10 (2012) Key words ö γ µ Graves disease and Hashimoto s thyroiditis are autoimmune thyroid diseases. Graves disease causes

More information

40: 127-130, 1994 11) Damjanov I, Moriber K, Catalano E, et al: Myelolipoma in a heterotopic adrenal gland. Light and electron microscopic findings. Can cer 44: 1350-1356, 1979 12) DeNavasquez S: Case

More information

83

83 Candida sppmssa Haemophilus influenzae consolidation consolidation consolidation consolidation consolidation consolidation knuckle sign Westermark sign Hampton s hump Borchardt enteropathy-associated

More information

The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursi

The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursi The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursing Professionals for Diabetic Outpatients Not Using

More information

CA CA19-9 CA19-9 CA CA CA19-9 ARCHITECT i 2000SR CLIA U/mL CA % CA CA

CA CA19-9 CA19-9 CA CA CA19-9 ARCHITECT i 2000SR CLIA U/mL CA % CA CA 原 著 30 22-29, 2015 CA19-9 CA19-9 CA19-9 2006 12013 6 CA19-9 32,508 37.0U/mL 790 2 CA19-9 320 CA19-9 ARCHITECT i 2000SRCLIA 0.0 37.0U/mL 8 4 1 2 18CA19-9 198.2 46.4 2,968 U/mL 5 3 2.5% CA19-9 2.5% CA19-9

More information

Fig. 1 Clinical Appearance on the Left Leg before Therapy Fig. 2 Clinical Appearance after Therapy Fig. 3 Histopathological Features of the Skin Lesio

Fig. 1 Clinical Appearance on the Left Leg before Therapy Fig. 2 Clinical Appearance after Therapy Fig. 3 Histopathological Features of the Skin Lesio Ryoji KANDA, M.D. and Seiichiro HATA, M.D. Fig. 1 Clinical Appearance on the Left Leg before Therapy Fig. 2 Clinical Appearance after Therapy Fig. 3 Histopathological Features of the Skin Lesion, Showing

More information

; cm 4. ; 2. ; 3. ; 5. 2 ; 120 ng/ml Mφ 6 7, 8 9

; cm 4. ; 2. ; 3. ; 5. 2 ; 120 ng/ml Mφ 6 7, 8 9 32, 21-25, 2012 CASLE 1 1 80 26 6 5 4 cm 1 2 CEA 3 4 CEA 2 44 22 2 3 1.5 cm 22 1. 1 ; 6 5 4 cm 4. ; 2. ; 3. ; 5. 2 ; 120 ng/ml 0-40 5 Mφ 6 7, 8 9 23 6. ; 9. ; 7. ; 10. ; 8. 7 10 CK3 CK3 24 1,2 3 2 8% 4,5

More information

1 Department of Legal Medicine, Toyama University School of Medicine 2 3 4 5 6 7 8 Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama VEGF Key words

More information

IgG4-related kidney disease

IgG4-related kidney disease 第 15 回 JSWN 総会特別講演 2017.5.26 @ TKP ガーデンシティ仙台 こんな時でもなければ話せない IgG4 関連疾患ウラ話 ( 抜粋 ) 佐伯敬子 (Takako Saeki) 長岡赤十字病院内科 ( 腎 リウマチ 膠原病 ) Nagaoka Red Cross Hospital Umehara H, Okazaki K, et al. Mod Rheumatol 2012:22:21-30

More information

1272 CHEMOTHERAPY MAR. 1975

1272 CHEMOTHERAPY MAR. 1975 1272 CHEMOTHERAPY MAR. 1975 VOL. 23 NO. 3 CHEMOTHERAPY 1273 Fig. 2 Minimal inhibitory concentration of aminoglycosides against 50 strains of Klebsiella Fig. 1 Minimal inhibitory concentration of aminoglycosides

More information

48-3 ‰{”R†i74-84†j

48-3 ‰{”R†i74-84†j Metallic Stents in the Gastrointestinal Tract Shiro Miyayama, M.D., Tetsuya Komatsu, M.D., Keiichi Taki, M.D., Tetsuya Minami, M.D., Chiharu Ito, M.D., Rieko Shinmura, M.D., Shigeyuki Takamatsu, M.D.,

More information

Fig. 1 Chest X-ray on admission, with infiltrative shadow in the right upper lung field. Fig. 2 Chest CT scan shows an infiltrative shadow, multiple b

Fig. 1 Chest X-ray on admission, with infiltrative shadow in the right upper lung field. Fig. 2 Chest CT scan shows an infiltrative shadow, multiple b congenital bronchial atresia, obstructive pneumonia Fig. 1 Chest X-ray on admission, with infiltrative shadow in the right upper lung field. Fig. 2 Chest CT scan shows an infiltrative shadow, multiple

More information

Unknown

Unknown Journal of Breast and Thyroid Sonology Journal of Breast and Thyroid Sonology Vol.3, No.3 July 2014 Original Article Clinical significance of classification of mixed-pattern tumor by breast ultrasound...

More information

スライド 1

スライド 1 1 2006 msv 2 2011 3 CT 2011 10mSv 10 40mSv 4 2012 217mSv 5 (CT) 2012 50 60mSv 6 2012 510mSv BRCA25 310 10mSv3% BRCA60-280% 3 5m Sv 1m Sv 12% . http://www.rea.or.jp/ire/pdf/report4.pdf 1.10 20 SMR 1.00

More information

Table 1. Numbers of Cancerous Pleurisy Cases According to Primary Site Table 2. Histological Type of Lung Carcinoma with Cancerous Pleurisy at Autopsy

Table 1. Numbers of Cancerous Pleurisy Cases According to Primary Site Table 2. Histological Type of Lung Carcinoma with Cancerous Pleurisy at Autopsy Clinicopathological Studies on Cancerous Pleurisy, with Emphasis on Extra-Pulmonary Malignancy Table 1. Numbers of Cancerous Pleurisy Cases According to Primary Site Table 2. Histological Type of Lung

More information

A Nutritional Study of Anemia in Pregnancy Hematologic Characteristics in Pregnancy (Part 1) Keizo Shiraki, Fumiko Hisaoka Department of Nutrition, Sc

A Nutritional Study of Anemia in Pregnancy Hematologic Characteristics in Pregnancy (Part 1) Keizo Shiraki, Fumiko Hisaoka Department of Nutrition, Sc A Nutritional Study of Anemia in Pregnancy Hematologic Characteristics in Pregnancy (Part 1) Keizo Shiraki, Fumiko Hisaoka Department of Nutrition, School of Medicine, Tokushima University, Tokushima Fetal

More information

A Study on Life-Table based on the Death Rate from a Specific Disease by Fumio Nakamura, M. D. Department of Hygiene Okayama University Medical School (Director: Professor Masahiko O. D., M. P. H.) In

More information

名称未設定-1

名称未設定-1 Study on Clinical Factors Affecting the Fungal Culture Test - Relevance of Dry Mouth - Yoshiko YAMAMURA, Yukihiro MOMOTA, Hideyuki TAKANO, Koichi KANI, Katsumi MOTEGI, Fumihiro MATSUMOTO, Masayuki AZUMA

More information

第61巻5・6号(12月号)/特集1頁目(本刷)

第61巻5・6号(12月号)/特集1頁目(本刷) Special Issue 1Sudden cardiac death symposium in Tokushima Special Issue 2How to do for your health? Reviews Original Epidemiologic problems of sudden death of school children in Tokushima Prefecture

More information

STUDIES ON THE RELATION BETWEEN LATE DUMPING SYNDROME AND GLUCAGON RESPONCES TO GLUCOSE Taisuke MATSUI The First Department of Surgery, Nara Medical U

STUDIES ON THE RELATION BETWEEN LATE DUMPING SYNDROME AND GLUCAGON RESPONCES TO GLUCOSE Taisuke MATSUI The First Department of Surgery, Nara Medical U STUDIES ON THE RELATION BETWEEN LATE DUMPING SYNDROME AND GLUCAGON RESPONCES TO GLUCOSE Taisuke MATSUI The First Department of Surgery, Nara Medical University, Kashihara (Director: Prof. H. Nakano) This

More information

16_.....E...._.I.v2006

16_.....E...._.I.v2006 55 1 18 Bull. Nara Univ. Educ., Vol. 55, No.1 (Cult. & Soc.), 2006 165 2002 * 18 Collaboration Between a School Athletic Club and a Community Sports Club A Case Study of SOLESTRELLA NARA 2002 Rie TAKAMURA

More information

Journal of Breast and Thyroid Sonology Journal of Breast and Thyroid Sonology Vol.2, No.1 January 2013 Overview History of JABTSJapan Association of Breast and Thyroid Sonology : Dawn of a JABTS Age; The

More information

semen quality or those without WBC in semen. In the patients with azoospermia and normal FSH levels (normogonadotropic azzospermia), the antibody (IgG

semen quality or those without WBC in semen. In the patients with azoospermia and normal FSH levels (normogonadotropic azzospermia), the antibody (IgG CLINICAL STUDIES OF UROGENITAL INFECTIONS WITH CHLAMYDIA TRACHOMA TIS Report 2. The Epidemiology of Chlamydial Infections in Okayama District in Japan and Detection of Antibodies to Chlamydiae in the Sera

More information

1) Perissat J, Collet DR, Belliard R : Gallstones ; laparoscopic treatment, intracorporeal lithotripsy followed by cholecystotomy on cholecystectomy. Endoscopy 21 : 373-374, 1989 2) Kato K, Matsuda M,

More information

Perspective-Taking Perspective-Taking.... Vol. No.

Perspective-Taking Perspective-Taking.... Vol. No. Nurses Thinking Process in Understanding Patients Unconscious Denial Tomoko Hayashi Key Words putting oneself in the patient s place, perspective-taking, misunderstand patient s perspective, modifying

More information

1) University Group Diabetes Program: A study of hypoglycemic agents on vascular complica- in patients with adult-onset tions diabetes. I. Design, methods and baseline results. Diabetes 19 (suppl. 2):

More information

EVALUATION OF MAGNETIC RESONANCE IMAGING (MRI) IN DIAGNOSIS OF ACOUSTIC NEUROMA-COMPARATIVE STUDY WITH PLAIN X-RAY AND CTS- KIMIHISA NOMURA, M.D., MAK

EVALUATION OF MAGNETIC RESONANCE IMAGING (MRI) IN DIAGNOSIS OF ACOUSTIC NEUROMA-COMPARATIVE STUDY WITH PLAIN X-RAY AND CTS- KIMIHISA NOMURA, M.D., MAK EVALUATION OF MAGNETIC RESONANCE IMAGING (MRI) IN DIAGNOSIS OF ACOUSTIC NEUROMA-COMPARATIVE STUDY WITH PLAIN X-RAY AND CTS- KIMIHISA NOMURA, M.D., MAKOTO SAKAI, M.D., ATSUSHI SHINKAWA, M.D. and HIROSATO

More information

Unknown

Unknown Journal of Breast and Thyroid Sonology Journal of Breast and Thyroid Sonology Vol.2, No.3 July 2013 Report The 30 th Meeting of Japan Association of Breast and Thyroid Sonology... 1 Department of Organ

More information

68 22 Proceeding Clinical features and diagnosis of lymphocytic infundibulo-hypophysitis IgG4 12 / 7/ IgG4 3/7 IgG

68 22 Proceeding Clinical features and diagnosis of lymphocytic infundibulo-hypophysitis IgG4 12 / 7/ IgG4 3/7 IgG 68 22 Proceeding Clinical features and diagnosis of lymphocytic infundibulo-hypophysitis IgG4 12 /7/5 26 78 2 4 6 11 11 IgG4 3/7 IgG4 2 21 1 1 1 4 4 2 5 3 IgG4 IgG4 IgG4 IgG4 MR 1 Tolosa-Hunt IgG4 2 IgG4

More information

1) i) Barber, M. et al.: Brit. Med J, 2, 565, 19'49. ii) Barber, M.F.G. J. Hayhoe and J. E. M. Whithead: Lancet, 1120 `1125, 1949.-2) Bergey: Bergey's Manual of Determinative Bacteriology 7 th Ed: (1958).-3)

More information

膵癌超音波診(案)

膵癌超音波診(案) 1 2 3 4 5 6 7 8 9 10 2009 7 6 2 a. invasive ductal carcinoma * 1 b. endocrine neoplasm c. Solid pseudopapillary neoplasm d. tumor producing pancreatitis * 2 * 1 invasive ductal carcinomas papillary adenocarcinoma

More information

29 28 39 1936 Acquiring technique and forming character in physical education after 1936 Analysis of articles of Kenji Shinozaki FUJIKAWA Kazutoshi The United Graduate School of Education Tokyo Gakugei

More information

Special IssueDiagnoses and therapeutic agents for age-related diseases Reviews Original Case reports β Medicinal drugs affecting on clinical laboratory blood test results and adverse effects of them

More information

TEM

TEM 29 28 55 A historical study of Hassaku Sumo Wrestling Focusing on the Origin of Hassaku Sumo Wrestling Festival of the Ookunitama Shrine MATSUMOTO Akiyuki Graduate School of Health and Sport Seience, Nippon

More information

CHEMOTHERAPY JUN Citrobacter freundii 27, Enterobacter aerogenes 26, Enterobacter cloacae 27, Proteus rettgeri 7, Proteus inconstans 20, Proteus

CHEMOTHERAPY JUN Citrobacter freundii 27, Enterobacter aerogenes 26, Enterobacter cloacae 27, Proteus rettgeri 7, Proteus inconstans 20, Proteus VOL. 32 S-4 CHEMOTHERAPY Fig. 1 Chemical structure of sodium cefoperazone Fig. 2 Chemical structure of sodium cefoperazone CHEMOTHERAPY JUN. 1984 Citrobacter freundii 27, Enterobacter aerogenes 26, Enterobacter

More information

3 1) Ormond, J.K.: Bilateral ureteral obstruction due to envelopment and compression by an inflamm atory retroperitoneal process. J. Urol.59: 1072-1079, 1948. (40) Cleveland Clin. Quart. 32 : 19-27, 1965.

More information

日本職業・災害医学会会誌第51巻第5号

日本職業・災害医学会会誌第51巻第5号 太田ら 同時多発性高血圧性脳葉出血の 1 手術例 図 1 搬入時 CT 上段 単純 CT 下段 造影 CT 図 2 術後の脳血管撮影検査では明らかな出血源は認めない 379 Reprint request: MULTIPLE SIMULTANEOUS HYPERTENSIVE LOBAR HEMORRHAGE Hirotsugu OHTA M.D. 1) and Akira YOKOTA M.D.

More information

3) Stedmann, E. et al.: Biochem. J., 29; 2107, 1935. 4) Reiss, M.. Hemphill, R. E. E ENature, 161 ; 18, 1948. 5) Tower, D. B. & D. MeEachern: Canada J. Reserch., 27; 105, 120, 132, 1949. 6) Wolleman, M.

More information

The clinical characteristics of Mycoplasma pneumoniae pneumonia in children younger than 6 years old Nobue Takeda1,2),Tomomichi Kurosaki1),Naruhiko Ishiwada2),Yoichi Kohno2) 1)Department of Pediatrics,Chiba

More information

CHEMOTHERAPY JUNE 1993 Table 1. Background of patients in pharmacokinetic study

CHEMOTHERAPY JUNE 1993 Table 1. Background of patients in pharmacokinetic study CHEMOTHERAPY JUNE 1993 Table 1. Background of patients in pharmacokinetic study VOL. 41 S 1 Table 2. Levels (Đg/ml or Đg/g) of S-1006 in serum, bile, and tissue (gallbladder) after oral administration

More information

p _08森.qxd

p _08森.qxd Foster care is a system to provide a new home and family to an abused child or to a child with no parents. Most foster children are youngsters who could not deepen the sense of attachment and relationship

More information

2012 Vol. 23 No pseudothrombophlebitis pseudothrombophlebitis

2012 Vol. 23 No pseudothrombophlebitis pseudothrombophlebitis pseudothrombophlebitis 5 424 163 38.1 26 6.1 5 1.2 230 2 3 66.4 51 80 2 3 2 2 1 2012 23 3 261-265 pseudothrombophlebitis 1 2011 7 11 30 2010 2 5 47 Fig. 1 Ultrasonography showed a low echoic cyst in the

More information

東洋医学雑誌

東洋医学雑誌 Vol.61 No.7 924-929, 2010 a b c d Naoki OKADA ad Masaru NATSUAKI b Takashi NISHIMOTO ac Nishimoto Clinic, 2-8-31 Koshienguchi, Nishinomiya, Hyogo 663-8113, Japan Department of Dermatology, Hyogo College

More information

indd

indd 12 61 1 2011 原著 1)2)5) 1) 1)2) 1)2)5) 1)3)5) 1)2) 1)2)5) 1)2) 1)2) 2) 2) 4) 1) 1) 2) 3) 4) 5) 2010 10 6 2010 12 6 A Comparative Study of the Effect and Discomfort Produced by Pharyngeal Anesthesia with

More information

日本消化器外科学会雑誌第23巻第2号

日本消化器外科学会雑誌第23巻第2号 Key words: carcinoma of the pancreatic head, carcinoma of the periampullary region, operative results of the pancreatic duodenal carcinoma, mode of tumor spread of the pancreatic duodenal carcinoma, factors

More information

Key words : Adverse reactions, Egg allergy, IgG antibody, Mills allergy, FAST

Key words : Adverse reactions, Egg allergy, IgG antibody, Mills allergy, FAST Key words : Adverse reactions, Egg allergy, IgG antibody, Mills allergy, FAST 13) Danaeus, A., Johansson, S. G. O., Foucard, T. & Ohman, S.: Clinical and immunogical aspects of food allergy in childhood.

More information

日本消化器外科学会雑誌第31巻第7号

日本消化器外科学会雑誌第31巻第7号 Key words: obstructive jaundice, biliary drainage, bile refeeding, hepatectomy Fig. 1 Animal models a: experiment I b: experiment 2 silicon tube Fig. 2 Experimantal design Sham Ope J - l r bile duct Zweeks

More information

4.1 % 7.5 %

4.1 % 7.5 % 2018 (412837) 4.1 % 7.5 % Abstract Recently, various methods for improving computial performance have been proposed. One of these various methods is Multi-core. Multi-core can execute processes in parallel

More information

Table 1. Antibacterial activitiy of grepafloxacin and other antibiotics against clinical isolates

Table 1. Antibacterial activitiy of grepafloxacin and other antibiotics against clinical isolates Table 1. Antibacterial activitiy of grepafloxacin and other antibiotics against clinical isolates Table 2-1. Summary of patients treated with grepafloxacin for respiratory infection 1) Out: outpatient,

More information

J No J. J

J No J. J 教育科学と教育実践 2 Science of Education and Educational Practice - A Perspective on the Controversy on the Science of Education in Post-War Japan Part Takeo TANAKA 1950 E. J. E. J. E. J. Abstract In the latter

More information

Mechanism of painful breast induced by cold stimulus Yoshinori ITOH (Nagoya) Dept. of Physiol., Nagoya Univ, Sch, of Med., Nagoya, Japan Abstract Cold colic pain response was first mentioned in Kinkiyoryaku,

More information

Endocrinological and statistical analysis of ovarian function in hysterectomized patients Masaya HAYAFUJI, Kazuaki KATAYAMA and Matsuto MOCHIZUKI Depa

Endocrinological and statistical analysis of ovarian function in hysterectomized patients Masaya HAYAFUJI, Kazuaki KATAYAMA and Matsuto MOCHIZUKI Depa Endocrinological and statistical analysis of ovarian function in hysterectomized patients Masaya HAYAFUJI, Kazuaki KATAYAMA and Matsuto MOCHIZUKI Department of Obstetrics and Gynecology, Kobe University

More information

Fig. 1. Chest X-ray film on admission showed a mass in the left middle lung field and multiple nodular densities in the bilateral lung fields. Fig. 3.

Fig. 1. Chest X-ray film on admission showed a mass in the left middle lung field and multiple nodular densities in the bilateral lung fields. Fig. 3. A Case of Slow-growing Mucous-producing Adenocarcioma of the Lung Key words: Mucous-producing lung adenocarcinoma, Slow-growing, Bronchial gland cell type adenocarcinoma, Adenoid cystic carcinoma Table

More information

Squamous metaplasia in the uterine cervix Kiichiro NODA Department obstetrics and gynecology, School of Medicine, Tohoku University The process of squamous metaplasia in the uterine cervix might be discussed

More information

ABSTRACT The Social Function of Boys' Secondary Schools in Modern Japan: From the Perspectives of Repeating and Withdrawal TERASAKI, Satomi (Graduate School, Ochanomizu University) 1-4-29-13-212, Miyamaedaira,

More information

48 * *2

48 * *2 374-1- 17 2 1 1 B A C A C 48 *2 49-2- 2 176 176 *2 -3- B A A B B C A B A C 1 B C B C 2 B C 94 2 B C 3 1 6 2 8 1 177 C B C C C A D A A B A 7 B C C A 3 C A 187 187 C B 10 AC 187-4- 10 C C B B B B A B 2 BC

More information

口腔癌の早期発見のために For the early detection of oral cancer Kazumasa Sugihara Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and M

口腔癌の早期発見のために For the early detection of oral cancer Kazumasa Sugihara Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and M Title 口腔癌の早期発見のために Author(s) 杉原, 一正 Citation 鹿児島大学歯学部紀要, 34: 3-11 Issue Date 2014 URL http://hdl.handle.net/10232/20682 http://ir.kagoshima-u.ac.jp 口腔癌の早期発見のために For the early detection of oral cancer Kazumasa

More information

1) Roth, J., Glick, S. M., Yalow, R. S. and Berson, S. A.: Hypoglycemia: A potent stimulus to secretion of growth hormone. Science, 140, 987-988, 1963. 2) Ogawa, N.: Routine Ultramicro-Measurement of Human

More information

2) Goetz, A., Tsuneishi, N.: Application of molecular filter membranes to the bacteriological analysis of water, J. Am. Water Works Assn., 43 (12): 943-969,1951. 3) Clark, H.F. et al.: The membrane filter

More information

DOUSHISYA-sports_R12339(高解像度).pdf

DOUSHISYA-sports_R12339(高解像度).pdf Doshisha Journal of Health & Sports Science, 4, 41-50 2012 41 A Case Study of the Comprehensive community sports clubs that People with Disability Participate in. Motoaki Fujita In this study, the interview

More information

THE JAPANESE JOURNAL OF PERSONALITY 2007, Vol. 15 No. 2, 217–227

THE JAPANESE JOURNAL OF PERSONALITY 2007, Vol. 15 No. 2, 217–227 2007 15 2 217 227 2007 1 2 445 238 207 1 7 7 (2005) (2005) (2006a) 2006a (2004) (assumed-competence) 218 15 2 1 2005 2004 (2004) (2004) (2004) 16PF (2006) 4 Hayamizu, 2002 2006a (2006a) 1 Hayamizu, Kino,

More information

Mix*: 2 bilateral Syme's amputation, 3 Syme's-B/K, 1 Syme's-A/K 1 bilateral through knee, 1 A/K through hip 2. Kegel, B., Carpenter, M. L. and Burgess, E. M.: Functional Capabilities of Lower Extremity

More information

6 1Bulletin of Tokyo University and Graduate School of Social Welfarepp73-86 2015, 10 372-0831 2020-1 2015 5 29 2015 7 9 : : : 1 A B C D E 4 A B A B A B A ] AB C D E 4 8 73 17 2 22 750 1 2 26 2 16 17 32

More information

Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution of female patients with blad

Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution of female patients with blad Key words: Female with bladder irritability, Subjective symptoms, Pyuria, Bacteriuria Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution

More information

00.\...ec5

00.\...ec5 Yamagata Journal of Health Science, Vol. 6, 23 Kyoko SUGAWARA, Junko GOTO, Mutuko WATARAI Asako HIRATUKA, Reiko ICHIKAWA Recently in Japan, there has been a gradual decrease in the practice of community

More information

;~ (Summary) The Study on the Effects of Foot Bathing on Urination Kumiko Toyoda School of Human Nursing, University of Shiga Prefecture Background Foot bathing is one of the important nursing care for

More information

東洋医学雑誌

東洋医学雑誌 Vol.65 No.4 321-333, 2014 a b c d e f g h Ikuro WAKAYAMA a Shuichi KATAI b Satoru YAMAGUCHI c Shoji SHINOHARA de Hitoshi YAMASHITA f Hideto KOMATSU gh Faculty of Health Sciences, Kansai University of Health

More information

Arthroscopic Treatment for Painful Bennett Lesions of the Shoulder in Baseball Players by M. Yoneda and K. Hayashida Department of Orthopaedic Surgery

Arthroscopic Treatment for Painful Bennett Lesions of the Shoulder in Baseball Players by M. Yoneda and K. Hayashida Department of Orthopaedic Surgery Arthroscopic Treatment for Painful Bennett Lesions of the Shoulder in Baseball Players by M. Yoneda and K. Hayashida Department of Orthopaedic Surgery, Osaka Kosei-Nenkin Hospital K. Izawa and S. Wakitani

More information

DISTRIBUTION OF NEUROPEPTIDES IN THE INFERIOR NASAL TURBINATE MUCOSA OF PATIENTS WITH ALLERGIC RHINITIS KAZUHIRO YAMAMOTO. M.D. Department of Otolaryngology, School of Medicine, Kitasato University, Sagamihara

More information

1 ) Birnberg et al; Am. J. Obst. Gyn., 54 :88E 1947. 2) Bromberg, Y.M. & Bercovici, B. : Acta Endocrin., 7; 71, 1956. 23 : 33, 1956; Fertil. and Steril. 3) Fluhmann, C. F. : The management of menstrual

More information

06_学術_関節単純X線画像における_1c_梅木様.indd

06_学術_関節単純X線画像における_1c_梅木様.indd Arts and Sciences X The formulation of femoral heard measurement corrected enlargement ratio using hip joints X-ray Imaging 1 2 1 1 1 2 Key words: Bipolar Hip Arthroplasty (BHA) Preoperative planning Enlargement

More information

Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic c

Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic c Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic clinic, Department of Ophthalmology, (Director: Prof

More information

1) Barat, I. u. Wagner, R.: Brauer, Beitrage Zur Klinik der Tub., Bd. 71 (1929) 2) Warnecke, F.: Zeitschr. f. Tbk. Bd. 54 (1929) 3) Leoni, Alfonso: Zbl. f. g. Tbk. Forsch. Bd. 33 (1930) 4) Jalavisto, Eva

More information

理学療法検査技術習得に向けた客観的臨床能力試験(OSCE)の試行

理学療法検査技術習得に向けた客観的臨床能力試験(OSCE)の試行 An Application of an Objective Structured Clinical Examination for Learning Skills in Assessment of Physical Therapy A Task Involving Measurements on the Range of Motion Test Chikako Fujita1) Hiroyasu

More information

FA

FA 29 28 15 1985 1993 The process of the labor negotiations of the Japan Professional Baseball Players Association, 1985 1993 ABE Takeru Graduate School of Social Science, Hitotsubashi University Abstract

More information

Title 泌尿器科領域に於ける17-Ketosteroidの研究 17-Ketosteroidの臨床的研究 第 III 篇 : 尿 Author(s) 卜部, 敏入 Citation 泌尿器科紀要 (1958), 4(1): 3-31 Issue Date URL

Title 泌尿器科領域に於ける17-Ketosteroidの研究 17-Ketosteroidの臨床的研究 第 III 篇 : 尿 Author(s) 卜部, 敏入 Citation 泌尿器科紀要 (1958), 4(1): 3-31 Issue Date URL Title 泌尿器科領域に於ける17-Ketosteroidの研究 17-Ketosteroidの臨床的研究 第 III 篇 : 尿 Author(s) 卜部, 敏入 Citation 泌尿器科紀要 (1958), 4(1): 3-31 Issue Date 1958-01 URL http://hdl.handle.net/2433/111559 Right Type Departmental Bulletin

More information

Title 社 会 化 教 育 における 公 民 的 資 質 : 法 教 育 における 憲 法 的 価 値 原 理 ( fulltext ) Author(s) 中 平, 一 義 Citation 学 校 教 育 学 研 究 論 集 (21): 113-126 Issue Date 2010-03 URL http://hdl.handle.net/2309/107543 Publisher 東 京

More information

Hairy cell leukemia Hepatosplenic T-cell lymphoma Mycosis fungoides Sézary syndrome Lymphomatoid papulosis Primary cutaneous gd T-cell lymphoma Peripheral T-cell lymphoma, NOS Angioimmunoblastic T-cell

More information

VOL. 37 NO. 3 Key words: Drug allergy, LMIT, Penams, Cephems, Cross-reactivity

VOL. 37 NO. 3 Key words: Drug allergy, LMIT, Penams, Cephems, Cross-reactivity VOL. 37 NO. 3 Key words: Drug allergy, LMIT, Penams, Cephems, Cross-reactivity CHEMOTHERAPY MAR. 1989 Mble 1. Allcrgy in parients nduced by penams VOL. 37 NO. 3 Table 2. Allergy in patients induced by

More information

CHEMOTHERAPY Table 1 Clinical effect of Sultamicillin

CHEMOTHERAPY Table 1 Clinical effect of Sultamicillin CHEMOTHERAPY CHEMOTHERAPY Table 1 Clinical effect of Sultamicillin CHEMOTHERAPY Fig. 1 MICs of sultamicillin against respiratory pathogenic Branhamella catarrhalis 62 strains, inoculum size 106CFU/m1 Fig.

More information

Fig. 1 A: Effects of intramuscular injection of glucagon on the blood glucose levels (changes from basal, ƒ BG) as compared with effects of scopolamin

Fig. 1 A: Effects of intramuscular injection of glucagon on the blood glucose levels (changes from basal, ƒ BG) as compared with effects of scopolamin Fig. 1 A: Effects of intramuscular injection of glucagon on the blood glucose levels (changes from basal, ƒ BG) as compared with effects of scopolamine butylbromide during upper gastrointestinal endoscopy.

More information

スライド 1

スライド 1 第 7 回埼玉県内科医会 埼玉県総合内科専門医会合同カンファレンス 自己免疫性膵炎 AIP autoimmune pancreatitis 2010.7.24 1 AIP の歴史 1961 年 Sarles H AIPの病態を最初に報告 1978 年中野ら本邦初 ステロイド著効例として世界初の報告 1991 年川口ら病理組織像はリンパ球 形質細胞の浸潤を伴う著明な線維化 : lymphoplasmacytic

More information

Key words: atypical pulmonary mycobacteriosis, Mycobacterium avium complex, bronchial washing, transbronchial lung biopsy Table 1 Background data of 14 patients Old pul. tbc: sclerosing pulmonary tuberculosis

More information

Web Stamps 96 KJ Stamps Web Vol 8, No 1, 2004

Web Stamps 96 KJ Stamps Web Vol 8, No 1, 2004 The Journal of the Japan Academy of Nursing Administration and Policies Vol 8, No 1, pp 43 _ 57, 2004 The Literature Review of the Japanese Nurses Job Satisfaction Research Which the Stamps-Ozaki Scale

More information

840 Geographical Review of Japan 73A-12 835-854 2000 The Mechanism of Household Reproduction in the Fishing Community on Oro Island Masakazu YAMAUCHI (Graduate Student, Tokyo University) This

More information

1) Asa, S. L., et al.: Immunohistochemical localization of neuron-specific enolase in the human hypophysis and pituitary adenoma, Arch. Pathol. Lab. Med., 108: 40 `43, 1984. 2) Chi, B. H. and Kim, R. C.:

More information

The Indirect Support to Faculty Advisers of die Individual Learning Support System for Underachieving Student The Indirect Support to Faculty Advisers of the Individual Learning Support System for Underachieving

More information

日本消化器外科学会雑誌第29巻第9号

日本消化器外科学会雑誌第29巻第9号 Table 1 Oligonucleotide primers used for RT-PCR and internal probes used for Southern blot hybridization Cytokine Primer Sequence (5'-3') 5' 3' Internal probe s' 3' Internal probe 5' 3' Internal probe

More information

Character of BUDO (Judo and Kendo) with reference to change of its judging rule Terushi MURAYAMA (Kyoto University of Education) Change of judging rule of Judo and Kendo as BUDO is summarized in an introduction,

More information

Author Workshop 20111124 Henry Cavendish 1731-1810 Biot-Savart 26 (1) (2) (3) (4) (5) (6) Priority Proceeding Impact factor Full paper impact factor Peter Drucker 1890-1971 1903-1989 Title) Abstract

More information

EVALUATION OF NOCTURNAL PENILE TUMESCENCE (NPT) IN THE DIFFERENTIAL DIAGNOSIS OF IMPOTENCE Masaharu Aoki, Yoshiaki Kumamoto, Kazutomi Mohri and Kazunori Ohno Department of Urology, Sapporo Medical College

More information

2 10 The Bulletin of Meiji University of Integrative Medicine 1,2 II 1 Web PubMed elbow pain baseball elbow little leaguer s elbow acupun

2 10 The Bulletin of Meiji University of Integrative Medicine 1,2 II 1 Web PubMed elbow pain baseball elbow little leaguer s elbow acupun 10 1-14 2014 1 2 3 4 2 1 2 3 4 Web PubMed elbow pain baseball elbow little leaguer s elbow acupuncture electric acupuncture 2003 2012 10 39 32 Web PubMed Key words growth stage elbow pain baseball elbow

More information

54-4.ren

54-4.ren 200454 4 604-619 1,3) 1,3) 1,3) 1) 1) 1) 2) 1) 2) 3) 2004.8.1 1) 2) 1) 3) 1 50 4) 2 BC 581 3 4) 4 54 4 2004.8.1 1 1 2 3 3 7 3 1 4 5 5 7 2 3 1 54 4 10 15 4 4) 5 1 6 ) 7) 7) 2004.8.1 8) 8) 8) 8 ) 2 9) c

More information

スポーツ選手における日常的トレーニングが味覚に及ぼす影響について

スポーツ選手における日常的トレーニングが味覚に及ぼす影響について Study on the Type Partition of Hospital Meals in Japan. -Relationship between Foods and Cooking Techniques- Tomoko WATANABE *1, Kunio ISHII *1, Sachiko SUGIZAKI *1, Kanako MURAMATSU *1, Megumi HIGUCHI

More information

_’£”R‡Ù‡©

_’£”R‡Ù‡© 29 31 38 2008 31 1) 2) 2) 3) 2) 1) 2008 302008 12 Activities of Daily Living ADL ADL 42 ADL ADL 1990 QOL Quality of Life QOL 1 QOL // 2 Activity of Daily Living ADL Performance Status PS ADL 3 1) 2) 3)

More information

™…

™… Review The Secret to Healthy Long Life Decrease in Oxidative and Mental Stress My motto is Health is not all. But nothing can be done without health. Health is the most important requisite for all human

More information