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症例報告 JNET 7:111-118, 2013 ステント単独で治療した非出血性椎骨動脈解離性動脈瘤の 2 例 - ステント単独治療の長期成績 - 1 2 Long-term results of non-hemorrhagic vertebral artery dissecting aneurysms treated by stent monotherapy Fumiaki ISAKA 1) Kazushi HIGUCHI 2) 1) 2) Abstract Objective - - ( ) Methods 2001 2002 2 5 3- (3 - ) Results 10- - Discussion - - Conclusion - Key Words ( ) ( ) 1 18 2013 17 2013 2 678-0232 1090 - 緒言 - 8 13 20 4 13 14 16 21 10 2 症例呈示 1. 対象および方法 2001 1 2002 12 2 JNET Vol.7 No.2 May 2013 111

5 2 1 2 3-7 2 1 3 2. 症例 1 患者 53 主訴 現病歴 14 27 Fig. 1A 20 1 81 200 治療 1 回目 7 2 270 150 2 14 14-300 7 25 4 8 4 9 4 4 4 6 33 10 4 5 6 4 1 Fig. 1B Fig. 1C 1 回目治療後の経過 Fig. 2 3 6 1 治療 2 回目 4 6 100 14 300 2 23 10 4 1 13 4 20 3 Fig. 2E 2 2 回目治療後の経過 1 3 - Fig. 3A 3 3 - Fig. 3B 7 3-3 Fig. 3C - Fig. 3E Fig. 3F 10 3 - Fig. 3D 10 3. 症例 2 患者 43 主訴 現病歴 7 0 15 Fig. 4A 112 JNET Vol.7 No.2 May 2013

A B C Fig. 1 Case 1 A Initial diagnostic angiogram of the right vertebral artery (anteroposterior view) shows a dissecting aneurysm. B Left vertebral angiogram during vessel reconstruction using a coronary stent. C Angiogram obtained immediately after stent deployment (dotted frame). A B C D E Fig. 2 Case 1 Serial vertebral angiography findings (A) 1 day, (B) 3 months, and (C) 6 months after reconstruction show progressive thrombosis; however, at 1 year (D) the aneurysmal sac is recanalized. Arrows indicate in-flow into the aneurysmal sac. E Angiogram immediately after deployment of a stent in the originally placed stent. Straightening of the parent artery with the stent facilitates flow stagnation in the aneurysm. The normalization of flow direction is shown by estimates of flow direction at each stage (indicated by arrows). 域は同側の AICA が灌流していた BTO にて 20 分間の 留置した 全身ヘパリン化を行った後 ACT=270 秒以 虚血耐性を確認した すでに Aspirin 81 mg の投与を受 上 RapidTransit 150 cm 2 marker および Agility14 soft けていたので さらに Ticlopidine 200 mg を治療 1 週間 にて解離腔を慎重に越えて microcatheter を basilar top 前に追加した に置いた 次いで guidewire を STABILIZER14-300 cm 治療 全身麻酔後 7Fr パトリーブを右 V2 segment に に交換し microcatheter を抜去した 血管内エコー上 JNET Vol.7 No.2 May 2013 113

A B E C Fig. 3 Case 1 Serial MIP (maximum intensity projection) images of 3D-CT (A) 1 day, (B) 3 years, (C) 7 years, and (D) 10 years after stent deployment in the originally placed stent demonstrate progressive thrombosis (arrows). E Saw-like image (arrows) on a right vertebral angiogram 7 years after reconstruction indicates slight protrusion of contrast medium through the stent struts. F Intravascular ultrasound shows neointima formation around the stent struts (arrows). F A D B C Fig. 4 Case 2 A Anteroposterior view of a right vertebral angiogram shows a dissecting aneurysm presenting as Wallenberg's syndrome. B Fluoroscopic image during reconstruction with a coronary stent (between the arrows) shows stasis of contrast medium within the aneurysm. C Angiogram a few minutes after stent deployment shows the straightened parent vessel (white arrow) and persistent stasis of the contrast medium at the venous phase. 114 JNET Vol.7 No.2 May 2013

enhanced plain A B C Fig. 5 Case 2 A 6 - ( ) B 7 (A) ( ) ( ) ( ) C 3-10 ( ) 10 10 4 2 4 3 3 9 3 7 18 10 4 0 6 3 7 10 Fig. 4B, C Fig. 4C 治療後の経過 3 6 - Fig. 5A 7 - Fig. 5B Fig. 5B 10 3 - Fig. 5C 10 考察 1990 18 1 2 3 3 18 2 11 1997 5 13 20 13 16 21 27 29 4 7 16 JNET Vol.7 No.2 May 2013 115

- 1 1 - - 2 1 10 2 1 15 21 1 4 14 4 7-4 14 12 3 9 2 10 19 2 21 3 3 16 81 200 2 21 1 1 2 116 JNET Vol.7 No.2 May 2013

1 6 16 21 17 9 2 21 10 2 結語 文 1 62 636-646 2008 2 14 1846-1853 1994 3-32 27-33 2011 4 64 212-217 献 2009 5 87 944-949 2007 6-45 22-26 2003 7-38 2346-2352 2007 8 33 193-199 2005 9 - -32 20-25 2011 10 25 460-469 1997 11 24 33-42 2002 12-29 34 41 2247-2253 2010 13 97 1306-1313 2002 14 64 632-643 2009 15 27 1861-1865 2006 16 - - 30 1351-1356 2009 17 53 243-249 2010 18 14 77-80 2008 19 20 1262-1275 2000 20 11 484-491 2002 21 - - JNET Vol.7 No.2 May 2013 117

20 108 1104-1118 2008 要旨 JNET 7:111-118, 2013 目的 - 10 2 症例 2001 2002 2 5 2 1 2 3 3 - 結果 10 考察 - 結論 118 JNET Vol.7 No.2 May 2013