A A SCU B 10 2 SCU 2.5 3 A 18 A B SCU 2003 12 2 12 3 12 10 12 2 15 1 HMGCoA - 28 -
14 1 Spreading Depression (SD) Cyclooxygenase-2 (COX-2) 10 12 2 12 10 15 1 HMGCoA 14 1 COX-2-29 -
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1) Arakawa S, Minematsu K, Hirano T, Tanaka Y, Hasegawa Y, Hayashida K, Yamaguchi T: Topographic distribution of misery perfusion in relation to internal and superficial borderzones. AJNR Am J Neuroradiol 24: 427-435, 2) Chambers B, Stork J, Kimura K, Abbott A, Levi C, Donnan G: Symptomatic carotid artery stenosis: Heterogeneity of destabilizing mechanisms? Stroke 34: e41, 3) Excutive Steering Committee on behalf of the SPORTIF Investegators. (Minematsu K): Stroke prevention with the oral direct thrombin inhibitor ximelagatra compared with warfarin in patients with non-valvular atrial fibrillation(sportif ): ranbomised controlled trial. Lancet 362, 1691-1698, 4) Hasegawa Y, Tagaya M, Fujimoto S, Hayashida K, Yamaguchi T, Minematsu K: Extracorporeal double filtrationn plasmapheresis in acute atherothrombotic brain infarction caused by major artery occlusive lesion. J Clin Apheresis 18, 167-174, 5) Kimura K, Minematsu K, Wada K, Yonemura K, Nakajima M: Clinical characteristics in transient ischemic attack patients with atrial fibrillation. Internal Medicine 42: 255-258, 6) Matsumoto N, Kimura K, Yokota C, Yonemura K, Wada K, Uchino M, Minematsu K: Early neurological deterioration represents recurrent attack in acute small non-lacunar stroke. J Neurogical Sci 217 151-155, 7) Saito K, Kimura K, Minematsu K, Shiraishi A, Nakajima M:Transient global amnesia associated with an acute infarction in the retrosplenium of the corpus callosum. Journal of the Neurological Sciences 210: 95-97, 8) Okamoto A, Sakata T, Mannami T, Baba S, Katayama Y, Matsuo H, Yasaka M, Minematsu K, Tomoike H, Miyata T. Population-based distribution of plasminogen activity and estimated prevalence and relevance to thrombotic diseases of plasminogen deficiency in the Japanese : the Suita Study. Journal of Thrombosis and Haemostasis, 1: 2397-2403, 9) Otani R, Kazui S, Tomimoto H, Minematsu K, Naritomi H: Clinical and radiographic features of lobar cerebral hemorrhage: Hypertensive versus non-hypertensive cases. Intern Med 42; 576-580, 10) Sawada K, Naiki M, Yago H, Matsushita K, Ohtsuki T, Kitagawa K, Matsumoto M, - 31 -
Hori M: Hypertension associated with reduced plasm thrombomodulin levels and a hypercoagulable state in rats. Clin. Exper. Hypertension. 25: 73-84, 11) The Edaravne Acute Brain Infarction Study Group: Effect of a Novel Free Radical Scavenger,Edaravone(MCI-186),onAcut Brain Infarction Randomized,Placebo-Controlled, Double-Blind Study at Multicenters. Cerebrovas Dis. 15; 222-229, 12) Yasaka M, Sakata T, Minematsu K, Naritomi H: Correction of INR by prothrombin complex concentrate and vitamin K in patients with warfarin related hemorrhagic complication. Thrombosis Research 108: 25-30, 13) Yasaka M, Minematsu K, Naritomi H, Sakata T, Yamaguchi T: Predisposing factors for enlargement of intracerebral hemorrhage in patients treated with warfarin. Thromb Haemost 89: 278-283, 14) Yasaka M, Oomura M, Ikeno K, Naritomi H, Minematsu K: Effect of prothrombin complex concentrate on INR and blood coagulation system in emergency patients treated with warfarin overdose. Ann Hematol 82: 121-123, 15) Yokota C, Kuge Y, Inoue H, Tagaya M, Kito G, Susumu T, Tamaki N, Minematsu K: Post-ischemic cyclooxygenase-2 expression is regulated by the extent of CBF reduction in non-human primates. Neurosci Lett. 341: 37-40, 16) Yokota C, Inoue H, Kuge Y, Abumiya T, Tagaya M, Hasegawa Y, Ejima N, Tamaki N, Minematsu K: Cyclooxygenase-2 expression associated with spreading depression in a primate model. J Cereb Blood Flow Metab 23: 395-398, 17) Yonemura K, Kimura K, Yasaka M, Minematsu K: Disappearrance of an 0scillating intraluminal thrombus in the carotid artery demonstrated by ultrasonography. Internal Medicine 42: 746-749, 1) Minematsu K: Evacuation of intracerebral hematoma is likely to be beneficial. Stroke. 34; 1567-1568, 1) : NIHSS ; 25, 312-321, - 32 -
2) 2003 25 215-229 3) Stroke Scale 25, 205-214, 4)?. 43, 10-18, 1) Stroke unit stroke care unit. 58 533-540 2). 58 841-847 3)?. 35 I 35 473-478 4). 29 19-22 5). Heart View 7 813-818 6) :. Medicina 40, 2003-2007, 7). BRAIN MEDICAL 15 13-19 8) 15: 837-845 9). 35 85-90 10). 58 494-499 11) Ca. Hypertension Focus 6 13-33 -
12) : Stroke Unit:. vol. XXIV No1, 28-33, 13) MRA. 80, 33-39, 14).. medicina 40, 1090-1091, 15) J-MUSIC -. vol5, 111-114, 16) 58 848-853 17). Heart View 7 772-773 18) : 37: 923-926, 19) : CT? 8:313-316, 20)., 35, 101-107, 21). CLINICAL NEUROSCIENCE 21 216-217 2003 22) (PFO) (ASA) Heart View 7 825-831 23) :. 07, 941-942, 24) 8: 25-30, 25) 53: 525-529, 26) 40: 223-227, 27). 11, 51-51, 2003-34 -
28) :. Heart View 7, 86-92, 2003 1) MRA. ( ) ( ). 113-118. 2). ( ) ( ). 207-208. 3). ( ) ( ). 211-213. 4). ( ). 146-150, 2003.. 5)?. ( ) 38-39 2003 6).. 2. 280-282, 2003 7).. 2. 280-282, 2003 8).. 2. 280-282, 2003 9) ( ) 329-343, 10) ). 285-289, 11). ( ) ( ). 163-170. 12). ( ) ( ).. 104-112,. 13). - 35 -
( ) 80-81 2003 14). ( ) ( ). 138-142. 15). ( ) ( ). 143-152. 16) :. ( ) 236-241 2003. 17). ABC pp77-85,. 18) CT MRI. ( ) ( ). 92-103. 19) Stroke Care Unit. ( ) 190-191 2003 20) ( ) 251-253 2003 21) PROGRESS..,, 65, 2003 22)? 2. ( ).? 2. 327. 23). ( ) ( ). 4-6. 24). ( ). 158-159. 25) Stroke Unit, Stroke Care Unit ( ). 210-211. 26) ( ) pp32-33 2003-36 -
27). ( ) ( ). 12-13. 28)??. ( ) ( ). 78-80. 29). ( ) ( ). 159-162. 30). ( ) ( ). 80-81. 31). ( ) ( ). 200-201. 32) 295 2003 33) 229 2003 34) 439 2003 35) 2003 pp.582-584 36) pp.1035-1036 2003 37) New Trends 2003 pp.53-60 38) CT (in press) 39). ( ) ( ) 177-185. - 37 -
40). ( ) ( ). 185-189. 41) ). 182-185 2003 42). ). 186-188 2003 43) ). 189-190 2003 44) ). 191-194 2003 45). 195-198 46) ). 199-201 2003 47). ( ). pp3-8,. 48) :. 151-158, 2003 49) - -. ( ) ( ). 190-197,.. 50).. - 2-60-71 2003.. - 38 -