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2 David J.LimSten O.HellstromCuneyt M.AlperAli And AlibiLauren O.BakaletzCraig A.BuchmanPer Caye-ThomasenRichard A.CholePhilippe HermanAnn HermanssonBurkhard HusslYukiko IinoTimothy T.K.Jung Hideyuki KawauchiJoseph KerschnerJizhen LinSaumil N.MerchantMichael M.PaparellaAnimal models;anatomy and pathology;pathogenesis;cell biology and geneticsrecent advances in otitis media report of the eighth research conferencesupplement194114(1) Part2: Stephen J.BarenkampPfaray L.OgraLauren O.BakaletzTasnee Chonmaitree Terho HeikkinenDavid S.HurstHideyuki KawauchiYuichi KuronoAlberto Leiberman Timothy F.MurphyJanak A.PatelTania Maria SihJoseph W.St Geme IiiLars-Eric StenforsMicrobiology and immunologyrecent advances in otitis media report of the eighth research conferencesupplement194114(1part2: Takaya Yamada, Shingo Kataoka, Keiko Ogasawara, Ryotaro Ishimitsu, Kazuhiro Hashiguchi, Tatsuo Suzuki, Hideyuki Kawauchi: Mucosal immunity of nasopharynx: an experimental study in TCR-transgenic (OVA23-3)mice. 2

3 Rhinology, 43, , 2005 Hidenori Takagi, Takachika Hiroi, Lijun Yang, Yoshifumi Tada, Yoshikazu Yuki, Kaoru Takamura, Ryotaro Ishimitsu, Hideyuki Kawauchi, Hiroshi Kiyono and Fumio TakaiwaA rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses. Proceedings of the National Academy of Sciences of the United States of America. 102(48) , 2005 Hideyuki Kawauchi, Takafumi Fuchiwaki, Tsuyoshi Umehara, Kaoru Takamura, Yasuhiko Shimizu, Noriaki Aoi, Shingo Kataoka Updated Diagnosis and Teratment Strategy of Invasive Aspergillosis in Paranasal Sinus our experience of 6 cases-. 24(1) Noriaki AoiTokuko MasudaDaisuke MurakamiToshiki YajimaHiroyuki MizubuchiHisakata YamadaHideyuki KawauchiYasunobu YoshikaiIL-15 prevents allergic rhinitis through reactivation of antigen-specific CD8+ cells. Journal of Allergy and Clinical Immunology 117(6): ,

4 Hideyuki kawauchi, Shingo Kataoka, Hisashi Ohga, Akemichi Murata, Mitsuhiro Kimura, Noriaki Aoi, Ichiro Morikura, Kaoru Takamura, Yasuhiko Shimizu : Clinical Efficacy of Cetirizine Hydrochrolide Administration in the Treatment of Cedar Pollinosis Patients Clinical Trial Over Four Seasons 24(2) Hideyuki Kawauchi, Maria Luisa Fiorella, Giuseppe Magliulo: The influence of tonsillar diseases and tonsillectomy on immune system. Proceedings paper of 6 TH international symposium on tonsils and mucosal barriers of the upper airways, edited by D. Passali et al, Monddini Co., Italy, in press. 4

5 Hideyuki KawauchiTsuyoshi UmeharaRyotaro IshimitsuAkemichi Murata Kaoru TakamuraNoriaki AoiRole of Toll-like receptors in the defense mechanism and maintenance of stagnant inflammation at upper respiratory tract mucosa.5 th Extraordinary International Symposium on Recent Advances in Otitis Media, AmsterdamThe Netherlands. April,

6 Takaya Yamada, Hideyuki KawauchiMucosal immunity of nasopharynx and tubotympanum an experimental study in TCR-trangenic(OVA23-3) mice- 12th International Congress of Mucosal Immunology, Boston USA, June, 2005 Tsuyoshi UmeharaRyotaro IshimitsuHisashi OgaAkemichi Murata, Ichiro MorikuraNoriaki AoiKaoru TakamuraHideyuki Kawauchi, Shingo Kataoka Role of Toll-Like Receptors in The Pathogenesis Of Persistent Inframmation In Nasal And Paranasal Sinus MucosaXVIII World Congress of International Federation of Oto-rhino-laryngological Societies, Rome Italy, Jun Mituhiro KimuraHideyuki KawauchiTsuyoshi UmeharaHiroshi Otani Development of the Olfactory Epithelium in Human Fetuses in Relation to Functional Maturation: Scanning Electron Microscopic ObservationsXVIII World Congress of International Federation of Oto-rhino-laryngological Societies, Rome Italy, Jun Hideyuki Kawauchi Pathogenesis of Allergic Rhinitis and Forthcoming Treatment Strategy from Immunnological StandpointXVIII World Congress of 6

7 International Federation of Oto-rhino-laryngological Societies, Rome Italy, Jun Hideyuki Kawauchi: Role of Toll-like receptors in the pathogenesis of paersistent inflammation in nasal and paranasal sinus mucosa. The 11th Congress of the International Rhinologic Society, Sydney, Oct Hideyuki Kawauchi: Clinical Efficacy of Cetirizine Hydrochrolide Administration in the Treatment of Cedar Pollinosis Patients - Clinical Trial over Four Seasons. The 11th Congress of the International Rhinologic Society, Sydney, Oct

8 Noriaki Aoi, Ryotaro Ishimitsu, Yasunobu Yoshikai and Hideyuki Kawauchi Interleukin-15 prevents allergic rhinitis through inhibition of degranulation from mast cells and activation of CD8 + T cells. Surface Barrier Immunology Study Group (SBARIS) 2 nd Meeting, Nago, Okinawa, Nov

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10 Kawauchi HideyukiPossible role of Toll-like-receptors in pathogenesis of rhinosinusitis and polyp formation. Organizing Committee of the 4 th International Consensus Conference on Nasal Polyposis, Moscow, Russia, May, 2006 Kawauchi HideyukiCytokine-modulators (Suplatast Tosilate/ macrolide) : How to downregulate the mucosal inflamation? Organizing Committee of the 4 th International Consensus Conference on Nasal Polyposis, Moscow, Russia, May, 2006 Hideyuki KawauchiMy favorite protocol of medical/surgical treatment of nasal polyposis: Pre-operative treatment, surgical technique, timing of surgery, and 10

11 prevention of recurrence. Organizing Committee of the 4 th Consensus Conference on Nasal Polyposis, Moscow, Russia, May, 2006 International Hideyuki Kawauchi, Kaoru Takamura, Hiroshi Kiyono, Fumio Takaiwa : A rice-based edible vaccine expressing multiple T cell epitopes of Cryj1 induces oral tolerance for an inhibition of nasal symptom of murine model of cedar pollinosis. The 21th Congress of the European Rhinologic Society & The 25 th International Symposium on infection and Allergy of the Nose, Tampere, Finland, June, 2006 Hideyuki Kawauchi: Pathogenesis of allergic rhinitis and forthcoming treatment strategy from immunological standpoint at the symposium on mucosal immunology and its clinical application. The 21th Congress of the European Rhinologic Society & The 25 th International Symposium on infection and Allergy of the Nose, Tampere, Finland, June,

12 Hideyuki KawauchiThe influence of tonsillar diseases and tonsillectomy on immune system. 6 TH INTERNATIONL SYMPOSIUM ON TONSILS AND MUCOSAL BARRIERS OF THE UPPER AIRWAYS I.S.T.M.B., Siena, Italy, September,

13 Yohei Katoh, Akemichi Murata, Shingo Kataoka, Hisashi Ohga, Mitsuhiro Kimura, Hideyuki Kawauchi Clinical outcome of patients with inverted papilloma in nasal cavity and paranasal sinuses Joint Meeting of Eight Department of Otolaryngology, Taipei, Taiwan, Nov., 2006 Akemichi Murata, Kaoru Takamura, Noriaki Aoi, Shingo Kataoka, Hiroshi Kiyono, Fumio Takaiwa, Hideyuki KawauchiThe suppression of nasal symptoms 13

14 in a murine model of allergic rhinitis with cedar pollen by oral tolerance with a rice-based edible vaccine expressing Cryj I and II-Tcell epitopes Joint Meeting of Eight Department of Otolaryngology, Taipei, Taiwan, Nov.,

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