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2 C.propinquumに Fig. 1A X ray film on admission. filtration of rt. lower Fig. 1C in- lung field. discharge. shadows Fig.1B CT trative shadows film on admission. of rt. middle 457 よる市 中 肺 炎 の1例 infil- lobe. Fig. 2 positive film on of rt. middle Gram trophils CT It exhibited 族 歴:特 記 事 項 な し.現 病 歴:洞 不全症 候 群 の た め 田 上 病 院 内 科 外 来 に 通 院 し て い た が, 平 成13(2001)年5月29日 よ り湿 性 咳 嗽 が 出 現 し,徐 年6月1日 々 に 増 強 し た た め,同 診 し た.胸 部X線 お よ び 胸 部CTに 浸 潤 影 を 認 め た た め,肺 当科 を 受 て右下肺 野 に 炎 の 診 断 の も と 当科 へ 入 院 と な っ た. 入 院 時 身 体 所 見:身 36.3,脈 長170cm,体 拍66/分,整,血 に 貧 血,黄 疸 な し.心 音 な し.腹 部:平 下 腿 浮 腫 な し.神 平 成15年6月20日 重60kg,体 圧172/86mmHg,結 音:清,雑 坦,軟,圧 温 膜 音 な し.肺:ラ 痛 な し.肝 経 学 的 異 常 所 見 な し. 脾 腫 な し. 2001, after of infiltrative lobe. stain of sputum. with phagocytosis of many palisading bacilli. Fig. 3 往 歴,家 15th September improvement Clinical course neugram-
3 Table 2A Comparison of biochemical feature between this case strain and strains previously described Table 2B MICs of a strain of C. propinquum
4 teriology Section, Centers for Disease Control, At- lanta. 4) Dominique de Briel, Francois Couderc, Philippe Riegel, Francois Jehl, Raymond Minck: High- Performance Liquid Chromatographyof Corynomycolic Acid as a Tool in Identification of Coryne- bacterium Species and Related Organism. J Clin Microbiol 1992; 30: ) C. Barreau, F. Bimet, M. Kiredjian, N. Rouillon, C. Bizet: Comparative Chemotaxonomic Studies of Mycolic Acid-Free Coryneform Bacteria of Hu- man Origin. J Clin Microbiol 1993; 31; ) P. Riegel, D. de Briel, G. Prevost, F. Jehl, H. Monteil: Proposal of Corynebacterium propinquum sp. nov. for Corynebacterium group ANF-3 strains. FEMS Microbiology Letters 1993; ) David L. Sewell, Marie B. Coyle, Guido Funke: P- rosthetic Valve Endocarditis Caused by Corynebacterium afermentans subsp. lipophilum (CDC Co- ryneform Group ANF-1). J Clin Micobiol 1995; 33: ) Michel Simonet, Dominique de Briel, Isabelle Boucot, Raymond Minck, Michel Veron: Coryneform Bacteria Isolated from Middle Ear Fluid. J Clin Microbiol 1993; 31: ) Francois N. R. Renaud, Alain Gregory, Claude Barreau, Dominique Aubel, Jean Freney: Identification of Turicella otitidis Isolated from a Patient with Otorrhea Associated with Surgery: Differentiation from Corynebacterium afermentans and Corynebacterium auris. J Clin Microbiol 1996; 34: ) S. Dealler, H. Malnick, D. Cammish: Intravenous 1) Rikitomi N, Nagatake T, Matsumoto K, Watanabe line infection caused by Corynebacterium CDC K, Mbaki N: Lower respiratory tract infections due to non-diphtheria in 8 patients with underlying lung diseases. Tohoku J Exp Med 1987; 153: ) Kamruddin Ahmed, Kenji Kawakami, Kiwao Wa tanabe, Hiroaki Mitsushima, Tsuyoshi Nagatake, Keizo Matsumoto: Corynebacterium pseudodiphtheriticum; A Respiratory Tract Pathogen. Clin Infect Dis 1995; 20: ) Hollis D. G. and R. E. Weaver Gram-positive organism: a guide to identification. Special Bac- group ANF-1. J Hosp Infect 1993; 23: ) Petit PL, Bok JW, Thompson J, Buiting AG, Coyie MB: Native-valve endocarditis due to CDC coryneform group ANF-3: Report of a case and review of corynebacterial endocarditis. Clin Infect Dis 1994; 19: ) Riegel P, Ruimy R, Christen R, Monteil H: Species identities and antimicrobial susceptibilities of corynebacteria isolated from various clinical sources. Eur J Clin Microbiol Infect Dis 1996; 15 (8) :
5 A Case of Community-acquired Pneumonia Caused by Corynebacterium Propinquum Internal Medicine, Institute of Tropical Medicine, Nagasaki University Corynebacterium propinquum, which is classified as Corynebacterium ANF-3, has not yet been described as a cause of the respiratory infections. In this paper, we reported a case of 67-year-old immunocompetent male with community-acquired pneumonia caused by C. propinquum. Our study suggested that Gram staining of the pulurent sputum was the most important diagnostic tool to determine the pathogenecity of this organism.
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