281 SCIENTIFIC MEETINGS & SEMINARS

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1 281 SCIENTIFIC MEETINGS & SEMINARS

2 282 CADM TSLC

3 283 Dok CADM TSLC VacA D CA Functional genomics mutagenesis Professor Brigitte Autran University Pierre et Marie Curie, Pitie Salpetriere Hospital, Paris, france Quest for immune correlates of protection and therapeutic vaccines against HIV. RCAI Imaging and new technologies at RIKEN. Application in Immunology Translin deficiency develops an imbalance of symmetric versus asymmetric divisions of hematopoietic stem cells

4 284 RCAI Role of Ras Erk pathway in B lymphocyte development and activation Associate Investigator, Baylor Institute for Immunology Research, Baylor Research Institute, Adjunct Associate Professor. Institute of Biomedical Studies, Baylor University Professor. Diane Mathis Joslin Diabetes Center, The Harvard Stem Cell Institute, Harvard University Novel determinants of the joint specificity of autoimmune inflammatory attack. Professor. Cristophe Benoist Joslin Diabetes Center, The Harvard Stem Cell Institute, Harvard University Commitment and differentiation to the FoxP Treg lineage. Kensuke Hirasawa, Assistant Professor Faculty of Medicine, Memorial University Ras Raf MEK and IFN induced antiviral response Secondary mutations as a mechanism of cisplatin resistance in BRCA mutated cancers Lessons learned from studies on a rare genetic disease, Fanconi anemia. Dr. Michael A.E. Ramsay, MD, FRCA President, Baylor Research Institute at Baylor University Medical Center Dallas, Texas Building Translational Research Platform of Cell Therapy and Personalized Health Center in Dallas RB p Prof.PaulJ.Coffer Molecular Immunology Lab, Department of Immunology, University Medical Center Utrecht, The Netherlands Divide, differentiate or die Novel molecular mechanisms underlying PKB mediated regulation of cell fate decisions Th Th Shozo IZUI Department of Pathology and Immunology, Faculty of Medicine, University of Geneva Molecular Pathogenesis of Systemic Lupus Erythematosus Tao Xu Director Professor Institute of Biophysics, Chinese Academy of Sciences Molecular Mechanisms Underlying Blood Glucose Control Dr. Marie Henriksson, Ph.D. Head of MTC Department Department for Microbiology, Tumor and Cell Biology MTC, Karolinska Institutet, Stockholm, Sweden

5 285 The Myc oncoprotein as a therapeutic target for cancer IKK SNAP Prof. Tsvee Lapidot The Weizmann Institute of Science Dynamic Interactions Between the Nervous and Immune Systems with the Microenvironment, Regulate Hematopoietic Stem Cells Tsukushi is a Frizzled ligand that, in competition with Wnt b, regulates the proliferation of retinal stem progenitor cells Klaus Strebel, Ph.D. Chief, Viral Biochemistry Section, Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health How HIV escapes intrinsic antiretroviral host defense mechanisms M.D., Ph.D. Staff Scientist, Laboratory of Molecular Biology NCI NIH How to reduce the immunogenicity of immunotoxins Scott P Henry, Ph.D., DABT, Vice President ISIS Pharmaceuticals, Toxicology Antisense Overview Department of Molecular Medicine, Mayo Clinic Rochester MN USA TRIMHIV Alexander Boldyrev M.V. Lomonosov Moscow State University and Research Center of Neurology, Russian Academy of Medical Sciences, Moscow Russia Possible role of NMDA receptors in non neuronal cells Ya Ming Hou Thomas Jefferson University Fast kinetics of CCA addition: Implication for quality control of trna maturation CARD

6 286 Susan M. Rosenberg Baylor College of Medicine, Houston, Texas, USA Mutation as a Stress Response and the Regulation of Evolvability Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll like receptor WPI IFReC Tolerogenic antigen presenting cells in the gut: dogmas and enigmas. Sec FACS HLA Flow ES ips Jak STAT PI K PDK Akt X

7 287 Dinshaw J. Patel Memorial Sloan Kettering Cancer Center GCOE Structural Biology of Riboswitch mediated Gene Regulation and Argonaute mediated Gene Silencing Dr. Ranjeny Thomas Professor, Diamantina Institute for Cancer, Immunology and Metabolic Medicine, Brisbane, Australia GCOE Of mice and men how research in dendritic cells exposes immunopathogenesis of autoimmune disease GCOE Professor, Christopher Baum, M.D. Dept. Experimental Hematology, Hannover Medical School GCOE Genetic modification of hematopoietic stem cells Bruce D. Walker, M.D. Partners AIDS Research Center Massachusetts General Hospital GCOE AIDS GCOE EML ALK Charles O. Elson University of Alabama at Birmingham GCOE Preventing disaster: regulation of CD T cell responses to microbiota flagellins GCOE Correlates of vaccine induced T cell immunity in HIV infection Prof. Jean Marc Reichhart Institut Universitaire de France GCOE The importance of ILin the regulation of neutrophil homeostasis

8 288 Dr. Marc Diederich Chief, Laboratoire de Biologie Moleculaire et Cellulaire de Cancer GCOE Glutathione based drug resistance mechanism of cancer Dr. Michel Gilliet M.D. Associate Professor Department of Immunology, M.D. Anderson Cancer Center, University of Texas GCOE Antimicrobial Peptides Break Innate Tolerance to Self nucleic Acids in Autoimmunity Dr. Masashi Narita M.D., Ph.D. Cancer Research UK, Cambridge Research Institute GCOE Cellular senescence in tumour suppression Prof.GlenN.Barber University of Miami, School of Medicine, Miami, FL GCOE STING is an endoplasmic reticulum adaptor that facilitates innate immune signaling. Yasunori Hayashi RIKEN MIT Neuroscience Research Center GCOE Composition of postsynaptic proteins during synaptic plasticity GCOE University of Utah, Department of Biochemistry GCOE HIV Dr. Manolis Pasparakis Department of Mouse Genetics and Inflammation, Institute for Genetics, University of Cologne GCOE IKK NF kb signalling in inflammation and cancer

9 289 EDUCATION

10 290 EMT Rab A Ras MAPK DNA non canonical Wnt NF B

11 291 DOK X ES ESiPS

12 ANNUAL REPORT 2008 March 25, 2009 Publishied by Tadashi Yamamoto, Ph.D. Dean, The Institute of Medical Science The University of Tokyo 4-6-1, Shirokanedai, Minato-ku, Tokyo TEL: Printed by Shobi Printing Co., Ltd. Tokyo, Japan

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