J. Jpn. Stomatol. Soc. 39(1) : , January, 1990 Clinical and histopathological studies of combination therapy with Cisplatin and Peplomycin (PP t
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1 J. Jpn. Stomatol. Soc. 39(1) : , January, 1990 Clinical and histopathological studies of combination therapy with Cisplatin and Peplomycin (PP therapy) for the carcinoma of the tongue Iwai TOHNAI, Hideki MIZUTANI, Minoru UEDA, Yusuke TAKEUCHI, Yasuyuki GOTOH, Tetsuo SHINODA, Yasushi HAYASHI, Makoto YAMBE and Toshio KANEDA Abstract : In the present study we investigated the clinical and histopathological effects of PP therapy by combined use of Cisplatin (CDDP) and Peplomycin (PEP) for 22 cases of the carcinoma of the tongue. The results were as follows ; 1. The clinical response rate was 81.8 % (including 2 CR, 16PR, 3MR and one NC). 2. The histopathological response rate was 50.0 % (including 2 Gradeo EI, 9 Grade II a, 4 Grade II b, 6 Grade III and one Grade IV). 3. The clinical effects did not always agree with the histopathological effects. There were discrepancies between clinical and histopathological effects, especially in PR determined by clinical findings. 4. From the view points of the WHO Grade, the histopathological effects by Obosi Shimosato classification results that there was effectiveness among 11 cases of 18 of Grade I (64.7 %), and none of Grade II and III. 5. From the view points of the mode of invasion, the histopathological effects results that there was effectiveness among 7 cases of 8 of 1, 2 type (87.5 %), 3 cases of 8 of 3 type (37.5 %), one case of 4 of 4C type (25.0 %) and none of 4D type. Department of Oral Surgery, Nagoya University School of Medicine (Chief : Prof. Toshio KANEDA) 65, Tsurumai-cho, Showa-ku, Nagoya, 466. Japan
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4 178 藤 内 水 谷,他 表7 Histological of response by 口科誌 っ た WHO mode invaslon Grade I症 例18例 組 織 効 果 のGrade II b以 1990年 の 中 で,病 理 上 の 有 効 例 は11例 で あ り,有 効 率 は,64.7%で あ っ た 逆 にWHO Grade 星 下 里 で の 病 理 組 II,III症 例 で は,大 織 効 果 のGrade II b以 上 の 有 効 例 は1例 も認 め な か った 表7は 病 理 組 織 効 果 を 浸 潤 様 式(山 分 類14))別 に み た もの で あ る 本 症 例 の中 で浸 潤 様 式 の1,2型 例,4D型2例 の 病 理 組 織 効 果 は,Grade 3例(有 IIb以 効 率37.5%),4C型 上 の 有 効 例 は7例(有 で の 有 効 例 は1例(有 本 小 浜 は8例,3型8例,4C型4 で あ っ た 浸 潤 様 式 の1,2型 効 率87.5%)と 効 率25.0%)で 高 か っ た 3型 あ っ た し か し4D型 での 有 効 例 で は有 効 例 は み られ な か った 次 に 代 表 的 な 症 例 を 供 覧 す る が,ま 写 真1は57歳,男 性,T2NOMO症 例 の 初 診 生 検 時 の 病 理 組 織 像 で あ る cancer れ 比 較 的 よ く分 化 して い るWHO分 2型 で あ る 写 真2は,PP療 下 に はfibrosisが pearlも 潤様式 ー ス施 行 後 の同 症 例 の病 理 組 織 像 で あ る 上 皮 生 検 時 の 病 理 組 織 像 で あ る が,高 IVで あ る 写 真3は,異 分 化 型 のWHO分 潤 様 式 は 境 界 線 が 不 明 瞭 で 大 小 の 腫 瘍 胞 巣 が 散 在 し て お り,3型 類1型 で で あ る 写 真4はPP療 ー ス施 行 後 の 同 症例 の 病 理 組 織 像 で ある 変 性 壊 死 に 陥 った 腫 瘍 細 胞 塊 の 周 囲 を 異 物 巨 細 胞 が 取 囲 ん で お り(写 真 の 矢 印),viableな 腫 瘍 細 胞 は み られ ず 大 星 下 里 分 類 の IIIで あ る 写 真1 多 くみ ら で あ る 浸 潤 様 式 は 境 界 線 が や や 乱 れ を 認 め,浸 法 を動 注 法 に よ り2コ 性,T1NOMO)の 法 を 動 注 法 に よ り2コ Grade 類1型 存 在 し筋 肉 内 ま で 及 ん で お り,大 星 下 里 分 類 のGrade な る 症 例(67歳,男 あ り,浸 ず 有効 例 に つ い て示 す 写 真2
5 39巻 舌 癌 のPP療 1号 写 真3 写 真5 規 則 な 索 状,胞 写 真6 男 性,T4NIMO症 在 性 に腫 瘍 細 胞 が 浸 潤 し て お り,や 例 の生 検 時 の病 理 組 織 像 で あ る 小 や 分 化 の 乏 し い 像 を示 し,WHO分 類 II型 で あ る 浸 潤 様 式 に つ い て は 境 界 線 が 不 明 瞭 で 腫 瘍 細 胞 は び 慢 性 に 浸 潤 して お り,4D型 で あ る 写 真6はPP療 巣 状,散 写 真4 次 に 無 効 例 に つ い て示 す 写 真5は69歳 179 法 の臨 床 効 果 と病 理 組 織 効果 法 を 動 注 法 に よ り2コ ー ス施 行 後 の 病 理 組 織 像 で あ る が,上 で 浸 潤 性 に シ ー ト状 充 実 性 胞 巣 を 形 成 しつ つ 増 殖 す る腫 瘍 細 胞 を 認 め,大 星.下 皮 側 か ら筋 層 に ま 里 分 類Grade I型 を示 して い る 考 頭 頸 部 領 域 癌 で のCDDPの 使 用 はLippmanら15)が 察 初 め て 報 告 し,Wittesら16)に よ っ て そ の有
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7 1) Rosenberg, B., Van Camp, L. et al : Inhibition of cell division in E. coli by electrolysis products from a platinum electrode. Nature 205 : , ) Nerrin, C. E.: Treatment of genitourinary tumors with cis-dichlorodiammineplatinum (II): Experience in 250 patient. Cancer Treat Rep 63 : , ) Wiltshaw, E., Kroner, T. et al : Phase I study of cis-dichlorodiammineplatinum (II) (NSC ) in advanced adenocarcinoma of the ovary. Cancer Treat Rep 60 : 55-62, ) Hall, D. J., Diasio, R. et al : Cis-platinum in gynecologic cancer : Amer J Obstet Gyn 141 : , ) Rossof, A. H., Bearden, J. D. et al : Phase I evaluation of cis-dimminedichloroplatinum (II) in lung cancer. Cancer Treat Rep 60 : , ) Wittes, R. E., Brescia, F. et al : Combination chemotherapy with cis-diamminedichloroplatinum (II) and bleomycin in tumors of the head and neck. Oncology 32 : , 1975.
8 7) Creagan, E. T., Fleming, T. R. et al : Cyclophosphamide, adriamycin, and cis-diamminedichloroplatinum ( II) in the treatment of patients with advanced head and neck cancer. Cancer 47 : , ) Evin, T. J. et al : Treatment of advanced souamous cell carcinoma of the head and neck with cisplatin, bleomycin, and methotrexate. Cancer Treat Rep 65 : , ) Shimosato, Y., Obosi, S. et al : Histological evaluation of effects of radiotherapy and chemotherapy for carcinoma-jap J Clin Oncol 1 : 19-35, ) Yamamoto, E., Kohama, G. et al : Mode of invasion, Bleomycin sensivity, and clinical course in squanous cell carcinoma of the oral cavity. Cancer 51 : , ) Lippman, A. J., Helson, C. et al : Clinical trials of cis-diamminedichloroplatinum (NSC ). Cancer Chemother Rep 57 : , ) Wittes, R. E., Cvitkovic E. et al : cis-dimminedichloroplatinum (II) (DDP) in the treatment of epidermoid carcinoma of the head and neck. Cancer Treat Rep 61 : , ) Horm, J., Abam, Y. et al : Long-term remisson of an advanced head and neck tumor following intra-arterial infusion with cis-dichlorodiammineplatinum. J Surgical Oncology 18 : , ) Hill, J. M., Loeb, E. et al : Clinical studies of platinum coordination compounds in the treat - ment of variaous malignant disease. Cancer Chemother Rep 59 : , ) Panettiere, F. J., Lehane, D. et al : Cis-platinum therapy of previously treated head and neck cancer. Medical and Pediatric Oncology 8 : , ) Baker, S. R., Makuch, R. W. et al : Preoperative cisplatin and bleomycin therapy in head and neck squamous carcinoma. Arch Otolaryngol 107 : , ) Pitman, S. W., Minor, D. R. et al : Sequential methotrexate leucovorin (MTX -LCV) and cis-platinum in head and neck cancer. Proc Am Assoc Cancer Res & Am. Soc Clin Oncol 20 : , ) Shapshay, S. M., Hong, W. K. et al : Histopathologic findings after Cis -platinum bleomycin therapy in advanced previously untreated head and neck carcinoma. Am J Surg 136: , 1978.
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