387 ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( )

386 B B () () ( ) ( ) ( )

387 ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( )

388 ( ) ( ) ( )

389 ( ) 2 ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( )

390 ( ) ( ) ( ) () () ( ) Hot flush

391 ( ) ( ) ( )

392 ( ( ) ( ) ( ) ( ) ( )

393 ( ) () ( ) ( ) ( ) ( )

痤 痤 痤 痤 痤 ( ) ( ) ( ) ( ) ( ) ( ) 394

395 ( ) ( ) ( ) ( ) ( ) ( ) () ( ) ( )

396 ( ) ( ) ( ) 2 1 2345 ( )

397

398 ( )

399 ( ) γ-gtp γ- γ-gtp γ-gtp γ-gtp γ-gtp γ-gtp

400 AST GOT GOT ALT GPT GPT GPT GPT GPT / TAT PT PT PT PT Ht Ht Hb Hb Hb

APTT APTT APTT APTT APT (APTT) ALP Al-P AL-P ALP ALP ACTH ACTH T-cho 401

402 P LDH LDH LDH BUN BUN BUN HDLC HDL-C classa classa RBC β- LDL- LDL LDL 125 CA125 CA125 CA125 CA125 CA125 CA125

403 N-NTx NTX NTx NTx NTx NTx NTx NTx ( ) (3+) WBC ()

( ) ( ) 404

405 0.5 mg1 mg2 mg 1 mg 1 mg 18 20 10 48 5 18 10 33 % 27.8 90.0 100.0 68.8 9 51 35 95 % % % % 0 0 0 2 10.0 2 0 0 0 2 4.2 2 0 0 0 2 10.0 2 0 0 0 2 4.2 2 0 0 0 2 10.0 2 0 0 0 2 4.2 2 0 0 0 2 10.0 2 0 0 0 2 4.2 2 4 22.2 5 8 40.0 11 3 30.0 5 15 31.3 21 3 16.7 4 5 25.0 6 3 30.0 4 11 22.9 14 0 0 0 4 20.0 4 1 10.0 1 5 10.4 5 1 5.6 1 0 0 0 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 1 10.0 1 2 4.2 2 0 0 0 1 5.0 1 1 10.0 1 2 4.2 2 1 5.6 1 6 30.0 6 7 70.0 14 14 29.2 21 0 0 0 1 5.0 1 4 40.0 5 5 10.4 6 0 0 0 0 0 0 3 30.0 3 3 6.3 3 0 0 0 0 0 0 3 30.0 3 3 6.3 3 1 5.6 1 0 0 0 1 10.0 1 2 4.2 2 0 0 0 2 10.0 2 0 0 0 2 4.2 2 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1

406 0.5 mg1 mg2 mg 1 mg 1 mg % % % % 0 0 0 9 45.0 9 3 30.0 3 12 25.0 12 0 0 0 8 40.0 8 3 30.0 3 11 22.9 11 0 0 0 1 5.0 1 0 0 0 1 2.1 1 1 5.6 1 1 5.0 1 1 10.0 1 3 6.3 3 0 0 0 1 5.0 1 1 10.0 1 2 4.2 2 1 5.6 1 0 0 0 0 0 0 1 2.1 1 0 0 0 4 20.0 5 7 70.0 7 11 22.9 12 0 0 0 4 20.0 5 7 70.0 7 11 22.9 12 2 11.1 2 6 30.0 6 1 10.0 1 9 18.8 9 1 5.6 1 2 10.0 2 0 0 0 3 6.3 3 0 0 0 2 10.0 2 0 0 0 2 4.2 2 1 5.6 1 0 0 0 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 5 25.0 7 2 20.0 2 7 14.6 9 0 0 0 3 15.0 3 0 0 0 3 6.3 3 0 0 0 0 0 0 2 20.0 2 2 4.2 2 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 2 0 0 0 1 2.1 2

407 0.5 mg1 mg2 mg 1 mg 1 mg 18 20 10 48 1 14 9 24 % 5.6 70.0 90.0 50.0 1 35 24 60 % % % % 0 0 0 2 10.0 2 0 0 0 2 4.2 2 0 0 0 2 10.0 2 0 0 0 2 4.2 2 1 5.6 1 6 30.0 8 3 30.0 4 10 20.8 13 1 5.6 1 4 20.0 5 3 30.0 3 8 16.7 9 0 0 0 3 15.0 3 1 10.0 1 4 8.3 4 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 1 5.0 1 5 50.0 6 6 12.5 7 0 0 0 0 0 0 4 40.0 4 4 8.3 4 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 8 40.0 8 3 30.0 3 11 22.9 11 0 0 0 8 40.0 8 3 30.0 3 11 22.9 11 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 4 20.0 5 7 70.0 7 11 22.9 12 0 0 0 4 20.0 5 7 70.0 7 11 22.9 12

0.5 mg1 mg2 mg 1 mg 1 mg % % % % 0 0 0 6 30.0 6 1 10.0 1 7 14.6 7 0 0 0 2 10.0 2 0 0 0 2 4.2 2 0 0 0 2 10.0 2 0 0 0 2 4.2 2 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 0 0 0 1 10.0 1 1 2.1 1 0 0 0 2 10.0 3 2 20.0 2 4 8.3 5 0 0 0 0 0 0 2 20.0 2 2 4.2 2 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 0 0 0 1 5.0 1 0 0 0 1 2.1 1 408

409 1 mg 2 4 mg 2 mg 12 6 15 33 5 5 14 24 % 41.7 83.3 93.3 72.7 8 19 56 83 % % % % 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 3 2 6.1 3 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 1 8.3 1 4 66.7 4 10 66.7 13 15 45.5 18 1 8.3 1 4 66.7 4 6 40.0 7 11 33.3 12 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 1 8.3 1 3 50.0 4 1 6.7 1 5 15.2 6 1 8.3 1 3 50.0 3 1 6.7 1 5 15.2 5 0 0 0 1 16.7 1 0 0 0 1 3.0 1

410 1 mg 2 4 mg 2 mg % % % % 2 16.7 3 1 16.7 3 8 53.3 12 11 33.3 18 0 0 0 0 0 0 4 26.7 4 4 12.1 4 2 16.7 2 1 16.7 1 0 0 0 3 9.1 3 0 0 0 1 16.7 1 2 13.3 2 3 9.1 3 1 8.3 1 1 16.7 1 0 0 0 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 5 33.3 7 5 15.2 7 0 0 0 0 0 0 5 33.3 6 5 15.2 6 0 0 0 0 0 0 1 6.7 1 1 3.0 1 1 8.3 1 2 33.3 2 2 13.3 2 5 15.2 5 1 8.3 1 2 33.3 2 2 13.3 2 5 15.2 5 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 2 16.7 2 1 16.7 1 1 6.7 1 4 12.1 4 1 8.3 1 0 0 0 1 6.7 1 2 6.1 2 1 8.3 1 0 0 0 0 0 0 1 3.0 1 0 0 0 1 16.7 1 0 0 0 1 3.0 1 0 0 0 2 33.3 2 5 33.3 6 7 21.2 8 0 0 0 2 33.3 2 2 13.3 2 4 12.1 4 0 0 0 0 0 0 3 20.0 3 3 9.1 3 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 3 50.0 3 3 20.0 4 6 18.2 7 0 0 0 0 0 0 3 20.0 3 3 9.1 3 0 0 0 2 33.3 2 0 0 0 2 6.1 2 0 0 0 1 16.7 1 0 0 0 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1

411 1 mg 2 4 mg 2 mg 12 6 15 33 3 3 13 19 % 25.0 50.0 86.7 57.6 4 3 47 54 % % % % 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 3 2 6.1 3 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 1 8.3 1 0 0 0 9 60.0 12 10 30.3 13 1 8.3 1 0 0 0 5 33.3 6 6 18.2 7 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 6 40.0 10 6 18.2 10 0 0 0 0 0 0 3 20.0 3 3 9.1 3 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 2 13.3 2 2 6.1 2 0 0 0 0 0 0 1 6.7 1 1 3.0 1

412 1 mg 2 4 mg 2 mg % % % % 0 0 0 0 0 0 5 33.3 5 5 15.2 5 0 0 0 0 0 0 5 33.3 5 5 15.2 5 1 8.3 1 0 0 0 2 13.3 2 3 9.1 3 1 8.3 1 0 0 0 2 13.3 2 3 9.1 3 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 2 16.7 2 1 16.7 1 1 6.7 1 4 12.1 4 1 8.3 1 0 0 0 1 6.7 1 2 6.1 2 1 8.3 1 0 0 0 0 0 0 1 3.0 1 0 0 0 1 16.7 1 0 0 0 1 3.0 1 0 0 0 0 0 0 4 26.7 5 4 12.1 5 0 0 0 0 0 0 3 20.0 3 3 9.1 3 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 0 0 0 1 6.7 1 1 3.0 1 0 0 0 2 33.3 2 3 20.0 4 5 15.2 6 0 0 0 0 0 0 3 20.0 3 3 9.1 3 0 0 0 2 33.3 2 0 0 0 2 6.1 2 0 0 0 0 0 0 1 6.7 1 1 3.0 1

393 316 80.4 1115 20 % 101 25.7 125 82 20.9 87 4 1.0 4 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 2 0.5 2 2 0.5 2 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 3 0.8 3 1 0.3 1 1 0.3 1 1 0.3 1 5 1.3 5 4 1.0 4 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 5 1.3 5 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 19 4.8 22 5 1.3 5 5 1.3 5 4 1.0 4 2 0.5 2 1 0.3 1 413

% 19 4.8 22 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 90 22.9 100 66 16.8 69 14 3.6 14 8 2.0 8 3 0.8 3 3 0.8 3 2 0.5 2 1 0.3 1 5 1.3 5 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 3 0.8 3 2 0.5 2 1 0.3 1 7 1.8 7 5 1.3 5 1 0.3 1 1 0.3 1 75 19.1 75 75 19.1 75 17 4.3 18 6 1.5 6 4 1.0 4 3 0.8 3 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 107 27.2 138 25 6.4 26 25 6.4 26 17 4.3 18 17 4.3 17 12 3.1 12 12 3.1 12 5 1.3 5 3 0.8 3 3 0.8 3 2 0.5 2 2 0.5 2 2 0.5 2 414

% 107 27.2 138 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 52 13.2 55 11 2.8 11 7 1.8 7 6 1.5 6 5 1.3 5 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 38 9.7 41 18 4.6 18 7 1.8 7 5 1.3 5 3 0.8 3 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 2 0.5 2 1 0.3 1 1 0.3 1 238 60.6 295 224 57.0 238 19 4.8 19 5 1.3 5 4 1.0 4 3 0.8 3 3 0.8 3 415

% 238 60.6 295 2 0.5 2 2 0.5 2 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 33 8.4 42 14 3.6 14 7 1.8 7 5 1.3 5 4 1.0 4 2 0.5 2 2 0.5 2 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 2 1 0.3 1 88 22.4 162 17 4.3 17 13 3.3 13 12 3.1 12 10 2.5 10 10 2.5 10 10 2.5 10 125 9 2.3 9 8 2.0 8 γ- 7 1.8 7 6 1.5 6-6 1.5 6 5 1.3 5 4 1.0 4 4 1.0 4 4 1.0 4 3 0.8 3 3 0.8 3 416

% 88 22.4 162 3 0.8 3 3 0.8 3 3 0.8 3 2 0.5 2 2 0.5 2 2 0.5 2 2 0.5 2 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 /1 0.3 1 8 2.0 9 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 417

(%) 393 289 73.5 785 19 (%) 3 0.8 4 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 4 1.0 4 4 1.0 4 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 4 1.0 4 2 0.5 2 1 0.3 1 1 0.3 1 17 4.3 20 5 1.3 5 4 1.0 4 4 1.0 4 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 67 17.0 73 47 12.0 49 13 3.3 13 7 1.8 7 2 0.5 2 1 0.3 1 1 0.3 1 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 7 1.8 7 5 1.3 5 1 0.3 1 1 0.3 1 418

(%) 74 18.8 74 74 18.8 74 7 1.8 8 4 1.0 4 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 67 17.0 79 22 5.6 23 12 3.1 13 11 2.8 11 9 2.3 9 7 1.8 7 7 1.8 8 3 0.8 3 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 40 10.2 41 11 2.8 11 6 1.5 6 3 0.8 3 3 0.8 3 3 0.8 3 2 0.5 2 2 0.5 2 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 21 5.3 21 12 3.1 12 4 1.0 4 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 419

(%) 234 59.5 283 223 56.7 237 17 4.3 17 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 24 6.1 30 12 3.1 12 4 1.0 4 3 0.8 3 3 0.8 3 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 2 70 17.8 130 16 4.1 16 12 3.1 12 12 3.1 12 10 2.5 10 8 2.0 8 125 8 2.0 8-6 1.5 6 γ- 5 1.3 5 4 1.0 4 4 1.0 4 4 1.0 4 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 3 0.8 3 420

(%) 70 17.8 130 3 0.8 3 2 0.5 2 2 0.5 2 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 1 0.3 1 /1 0.3 1 421

135 135 % 100.0 1055 11 % 115 85.2 236 103 76.3 156 9 6.7 9 8 5.9 8 8 5.9 8 7 5.2 7 6 4.4 6 4 3.0 7 3 2.2 3 3 2.2 3 3 2.2 3 3 2.2 3 2 1.5 2 2 1.5 2 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 2 1.5 2 1 0.7 1 1 0.7 1 3 2.2 3 3 2.2 3 4 3.0 4 4 3.0 4 1 0.7 1 1 0.7 1 7 5.2 7 6 4.4 6 1 0.7 1 14 10.4 18 6 4.4 6 3 2.2 3 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 422

% 57 42.2 87 41 30.4 53 13 9.6 14 5 3.7 5 4 3.0 4 4 3.0 4 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 2 1 0.7 1 1 0.7 1 12 8.9 13 3 2.2 3 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 9 6.7 13 6 4.4 7 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 10 7.4 10 9 6.7 9 1 0.7 1 15 11.1 16 13 9.6 14 2 1.5 2 14 10.4 16 7 5.2 7 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 78 57.8 190 26 19.3 31 23 17.0 28 17 12.6 19 17 12.6 18 12 8.9 16 10 7.4 11 10 7.4 10 8 5.9 9 6 4.4 7 6 4.4 7 5 3.7 5 5 3.7 5 3 2.2 3 3 2.2 3 423

% 78 57.8 190 3 2.2 3 2 1.5 2 2 1.5 2 2 1.5 3 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 44 32.6 64 9 6.7 10 8 5.9 9 7 5.2 7 7 5.2 9 5 3.7 5 4 3.0 4 3 2.2 3 3 2.2 3 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 34 25.2 53 16 11.9 17 7 5.2 8 5 3.7 6 3 2.2 4 3 2.2 5 2 1.5 2 2 1.5 3 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 6 4.4 7 5 3.7 5 1 0.7 1 1 0.7 1 104 77.0 152 97 71.9 102 12 8.9 16 8 5.9 9 6 4.4 7 3 2.2 3 424

% 104 77.0 152 3 2.2 3 3 2.2 3 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 29 21.5 39 11 8.1 11 6 4.4 6 5 3.7 6 5 3.7 6 2 1.5 2 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 50 37.0 104 15 11.1 15 9 6.7 9 γ- 7 5.2 7 7 5.2 7 6 4.4 6 5 3.7 5 5 3.7 5 4 3.0 4 4 3.0 4 3 2.2 3 3 2.2 3 3 2.2 3 2 1.5 3 2 1.5 2 2 1.5 2 2 1.5 3 2 1.5 2 2 1.5 2 2 1.5 2 2 1.5 2 2 1.5 2 125 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 425

% 17 12.6 19 7 5.2 7 2 1.5 2 2 1.5 2 2 1.5 3 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 426

135 120 % 88.9 433 7 % 7 5.2 9 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 2 1.5 2 2 1.5 2 4 3.0 4 3 2.2 3 1 0.7 1 6 4.4 7 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 36 26.7 49 25 18.5 29 8 5.9 8 4 3.0 4 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 4 3.0 5 3 2.2 4 1 0.7 1 7 5.2 7 7 5.2 7 13 9.6 14 12 8.9 13 1 0.7 1 1 0.7 1 1 0.7 1 427

% 37 27.4 62 14 10.4 14 13 9.6 14 5 3.7 5 5 3.7 5 4 3.0 4 4 3.0 5 3 2.2 3 3 2.2 3 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 21 15.6 27 7 5.2 7 4 3.0 4 2 1.5 4 2 1.5 2 2 1.5 2 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 8 5.9 12 5 3.7 5 2 1.5 3 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 2 1 0.7 1 1 0.7 1 103 76.3 145 97 71.9 102 12 8.9 16 8 5.9 8 3 2.2 3 3 2.2 3 3 2.2 3 2 1.5 2 2 1.5 2 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 428

% 17 12.6 21 8 5.9 8 5 3.7 5 2 1.5 2 1 0.7 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 33 24.4 64 11 8.1 11 8 5.9 8 γ- 4 3.0 4 3 2.2 3 3 2.2 3 3 2.2 3 3 2.2 3 2 1.5 2 2 1.5 3 2 1.5 2 2 1.5 3 2 1.5 2 125 2 1.5 2 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 1 0.7 1 429

430 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg 21 25 26 72 61 60 62 183 13 17 13 43 46 46 45 137 % 61.9 68.0 50.0 59.7 75.4 76.7 72.6 74.9 24 33 32 89 116 123 116 355 0 5 3 8 0 1 5 6 % % % % % % % % 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 7 11.5 10 11 18.3 12 6 9.7 7 24 13.1 29 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 4 6.6 4 8 13.3 8 6 9.7 6 18 9.8 18 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 1.7 1 0 0.0 0 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 2 mg 2 mg 4 2 mg 5 1 mg2 mg4 mg 129 126 9 393 135 528 45 129 121 7 316 135 451 39 % 100.0 96.0 77.8 80.4 100.0 85.4 86.7 645 648 26 1115 1055 2170 207 6 5 0 20 11 31 4 % % % % % % % 73 56.6 91 72 57.1 102 4 44.4 5 101 25.7 125 115 85.2 236 216 40.9 361 23 51.1 26 61 47.3 65 62 49.2 68 3 33.3 4 82 20.9 87 103 76.3 156 185 35.0 243 21 46.7 21 2 1.6 2 1 0.8 1 0 0.0 0 3 0.8 3 9 6.7 9 12 2.3 12 0 0.0 0 3 2.3 3 3 2.4 3 0 0.0 0 3 0.8 3 8 5.9 8 11 2.1 11 0 0.0 0 4 3.1 4 3 2.4 3 0 0.0 0 4 1.0 4 6 4.4 6 10 1.9 10 1 2.2 1 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 8 5.9 8 9 1.7 9 1 2.2 1 1 0.8 1 3 2.4 3 0 0.0 0 1 0.3 1 7 5.2 7 8 1.5 8 0 0.0 0 2 1.6 2 1 0.8 1 0 0.0 0 3 0.8 3 4 3.0 7 7 1.3 10 0 0.0 0 1 0.8 1 3 2.4 3 0 0.0 0 2 0.5 2 3 2.2 3 5 0.9 5 0 0.0 0 0 0.0 0 2 1.6 2 0 0.0 0 2 0.5 2 3 2.2 3 5 0.9 5 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 3 2.2 3 4 0.8 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 3 2.2 3 4 0.8 4 0 0.0 0 2 1.6 2 1 0.8 1 0 0.0 0 3 0.8 3 1 0.7 1 4 0.8 4 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 1 0.3 1 2 1.5 2 3 0.6 3 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 2 0.5 2 1 0.7 1 3 0.6 3 1 2.2 1

431 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 7 11.5 10 11 18.3 12 6 9.7 7 24 13.1 29 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 73 56.6 91 72 57.1 102 4 44.4 5 101 25.7 125 115 85.2 236 216 40.9 361 23 51.1 26 2 1.6 2 1 0.8 1 0 0.0 0 2 0.5 2 0 0.0 0 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 1 11.1 1 1 0.3 1 1 0.7 1 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 1.5 2 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 1.5 2 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 1.5 2 2 0.4 2 0 0.0 0 1 0.8 1 3 2.4 3 0 0.0 0 1 0.3 1 1 0.7 1 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 2 1.6 3 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 1 2.2 1 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0

432 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 7 11.5 10 11 18.3 12 6 9.7 7 24 13.1 29 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 73 56.6 91 72 57.1 102 4 44.4 5 101 25.7 125 115 85.2 236 216 40.9 361 23 51.1 26 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 2.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 1.6 2 2 1.6 2 0 0.0 0 3 0.8 3 2 1.5 2 5 0.9 5 3 6.7 3 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 3 6.7 3 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0

1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.3 2 1 1.7 1 1 1.6 1 4 2.2 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 1.7 1 1 1.6 1 3 1.6 3 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 4.0 1 1 3.8 1 2 2.8 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 433 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 1 0.8 1 0 0.0 0 0 0.0 0 5 1.3 5 3 2.2 3 8 1.5 8 4 8.9 4 1 0.8 1 0 0.0 0 0 0.0 0 4 1.0 4 3 2.2 3 7 1.3 7 3 6.7 3 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 2.2 1 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 4 3.0 4 5 0.9 5 4 8.9 4 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 4 3.0 4 5 0.9 5 4 8.9 4 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 1 0.7 1 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 3 2.3 3 5 4.0 7 0 0.0 0 5 1.3 5 7 5.2 7 12 2.3 12 0 0.0 0 0 0.0 0 3 2.4 4 0 0.0 0 0 0.0 0 6 4.4 6 6 1.1 6 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 2 0.5 2 1 0.7 1 3 0.6 3 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0

434 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 0 0.0 0 0 0.0 0 2 7.7 4 2 2.8 4 1 1.6 1 2 3.3 3 2 3.2 2 5 2.7 6 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 1 1.7 1 2 3.2 2 3 1.6 3 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 3 14.3 5 4 16.0 4 2 7.7 2 9 12.5 11 8 13.1 8 12 20.0 17 10 16.1 11 30 16.4 36 3 14.3 5 1 4.0 1 0 0.0 0 4 5.6 6 5 8.2 5 9 15.0 9 5 8.1 5 19 10.4 19 0 0.0 0 0 0.0 0 2 7.7 2 2 2.8 2 1 1.6 1 3 5.0 3 3 4.8 3 7 3.8 7 0 0.0 0 3 12.0 3 0 0.0 0 3 4.2 3 0 0.0 0 4 6.7 4 1 1.6 1 5 2.7 5 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.3 2 0 0.0 0 0 0.0 0 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.2 2 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 11 8.5 11 8 6.3 8 1 11.1 1 19 4.8 22 14 10.4 18 33 6.3 40 3 6.7 3 4 3.1 4 3 2.4 3 0 0.0 0 5 1.3 5 6 4.4 6 11 2.1 11 2 4.4 2 3 2.3 3 1 0.8 1 0 0.0 0 4 1.0 4 3 2.2 3 7 1.3 7 0 0.0 0 0 0.0 0 0 0.0 0 1 11.1 1 5 1.3 5 0 0.0 0 5 0.9 5 1 2.2 1 1 0.8 1 1 0.8 1 0 0.0 0 2 0.5 2 2 1.5 2 4 0.8 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 2 1.5 2 3 0.6 3 0 0.0 0 1 0.8 1 3 2.4 3 0 0.0 0 1 0.3 1 1 0.7 1 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 1 0.7 1 2 0.4 2 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 1 0.7 1 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 50 38.8 52 58 46.0 72 1 11.1 1 90 22.9 100 57 42.2 87 147 27.8 187 7 15.6 7 43 33.3 44 51 40.5 53 0 0.0 0 66 16.8 69 41 30.4 53 107 20.3 122 4 8.9 4 5 3.9 5 10 7.9 10 0 0.0 0 14 3.6 14 13 9.6 14 27 5.1 28 1 2.2 1 0 0.0 0 2 1.6 2 0 0.0 0 8 2.0 8 5 3.7 5 13 2.5 13 2 4.4 2 0 0.0 0 1 0.8 1 1 11.1 1 3 0.8 3 4 3.0 4 7 1.3 7 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 2 0.5 2 4 3.0 4 6 1.1 6 0 0.0 0 2 1.6 2 3 2.4 3 0 0.0 0 3 0.8 3 1 0.7 2 4 0.8 5 0 0.0 0

435 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 3 14.3 5 4 16.0 4 2 7.7 2 9 12.5 11 8 13.1 8 12 20.0 17 10 16.1 11 30 16.4 36 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.3 2 2 3.3 2 0 0.0 0 4 2.2 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 50 38.8 52 58 46.0 72 1 11.1 1 90 22.9 100 57 42.2 87 147 27.8 187 7 15.6 7 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 2 1.6 2 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 3 2.4 4 0 0.0 0 5 1.3 5 12 8.9 13 17 3.2 18 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 2 0.5 2 2 1.5 2 4 0.8 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 3 2.2 3 3 0.6 3 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 1.5 2 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0

1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.3 2 2 3.3 2 0 0.0 0 4 2.2 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 2 3.2 2 3 1.6 3 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 1 1.6 1 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 436 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 1 0.8 1 3 2.4 4 0 0.0 0 5 1.3 5 12 8.9 13 17 3.2 18 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 3 0.8 3 9 6.7 13 12 2.3 16 1 2.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 6 4.4 7 6 1.1 7 1 2.2 1 0 0.0 0 0 0.0 0 0 0.0 0 2 0.5 2 1 0.7 1 3 0.6 3 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 5 3.9 5 10 7.9 10 0 0.0 0 7 1.8 7 10 7.4 10 17 3.2 17 1 2.2 1 3 2.3 3 10 7.9 10 0 0.0 0 5 1.3 5 9 6.7 9 14 2.7 14 1 2.2 1 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0

437 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 2 9.5 2 1 4.0 1 1 3.8 1 4 5.6 4 3 4.9 3 2 3.3 2 2 3.2 2 7 3.8 7 2 9.5 2 1 4.0 1 1 3.8 1 4 5.6 4 3 4.9 3 2 3.3 2 2 3.2 2 7 3.8 7 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.3 2 4 6.7 4 0 0.0 0 6 3.3 6 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 3 5.0 3 0 0.0 0 4 2.2 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 1.7 1 0 0.0 0 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 4 19.0 4 4 16.0 5 3 11.5 5 11 15.3 14 14 23.0 15 12 20.0 14 15 24.2 17 41 22.4 46 2 9.5 2 3 12.0 4 3 11.5 3 8 11.1 9 2 3.3 2 3 5.0 3 5 8.1 5 10 5.5 10 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 2 3.3 2 0 0.0 0 1 1.6 1 3 1.6 3 1 4.8 1 0 0.0 0 1 3.8 1 2 2.8 2 4 6.6 4 4 6.7 4 3 4.8 3 11 6.0 11 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 2 3.3 2 3 4.8 3 6 3.3 6 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 64 49.6 64 89 70.6 90 0 0.0 0 75 19.1 75 15 11.1 16 90 17.0 91 5 11.1 6 64 49.6 64 88 69.8 89 0 0.0 0 75 19.1 75 13 9.6 14 88 16.7 89 5 11.1 5 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 2 1.5 2 2 0.4 2 1 2.2 1 11 8.5 12 5 4.0 5 0 0.0 0 17 4.3 18 14 10.4 16 31 5.9 34 2 4.4 2 2 1.6 2 1 0.8 1 0 0.0 0 2 0.5 2 7 5.2 7 9 1.7 9 2 4.4 2 2 1.6 2 2 1.6 2 0 0.0 0 6 1.5 6 2 1.5 2 8 1.5 8 0 0.0 0 4 3.1 4 1 0.8 1 0 0.0 0 4 1.0 4 1 0.7 1 5 0.9 5 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 3 0.8 3 2 1.5 2 5 0.9 5 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 52 40.3 73 51 40.5 84 3 33.3 5 107 27.2 138 78 57.8 190 185 35.0 328 14 31.1 17 6 4.7 6 11 8.7 13 1 11.1 1 25 6.4 26 23 17.0 28 48 9.1 54 1 2.2 1 12 9.3 13 5 4.0 5 1 11.1 1 17 4.3 18 26 19.3 31 43 8.1 49 3 6.7 3 11 8.5 12 13 10.3 13 1 11.1 1 25 6.4 26 17 12.6 19 42 8.0 45 2 4.4 2 6 4.7 6 7 5.6 7 0 0.0 0 12 3.1 12 17 12.6 18 29 5.5 30 1 2.2 1

438 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 4 19.0 4 4 16.0 5 3 11.5 5 11 15.3 14 14 23.0 15 12 20.0 14 15 24.2 17 41 22.4 46 1 4.8 1 1 4.0 1 0 0.0 0 2 2.8 2 3 4.9 3 1 1.7 1 2 3.2 2 6 3.3 6 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 1.7 1 0 0.0 0 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 1 1.6 1 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 52 40.3 73 51 40.5 84 3 33.3 5 107 27.2 138 78 57.8 190 185 35.0 328 14 31.1 17 8 6.2 8 5 4.0 5 1 11.1 1 17 4.3 17 12 8.9 16 29 5.5 33 2 4.4 2 11 8.5 11 9 7.1 10 0 0.0 0 12 3.1 12 8 5.9 9 20 3.8 21 1 2.2 1 2 1.6 2 5 4.0 6 0 0.0 0 3 0.8 3 10 7.4 10 13 2.5 13 1 2.2 1 1 0.8 1 1 0.8 1 0 0.0 0 2 0.5 2 10 7.4 11 12 2.3 13 1 2.2 1 3 2.3 3 0 0.0 0 1 11.1 1 5 1.3 5 5 3.7 5 10 1.9 10 1 2.2 1 0 0.0 0 2 1.6 2 0 0.0 0 2 0.5 2 6 4.4 7 8 1.5 9 1 2.2 1 1 0.8 1 3 2.4 3 0 0.0 0 1 0.3 1 5 3.7 5 6 1.1 6 0 0.0 0 0 0.0 0 3 2.4 3 0 0.0 0 0 0.0 0 6 4.4 7 6 1.1 7 0 0.0 0 2 1.6 2 1 0.8 1 0 0.0 0 3 0.8 3 2 1.5 2 5 0.9 5 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 2 0.5 2 3 2.2 3 5 0.9 5 0 0.0 0 2 1.6 2 6 4.8 6 0 0.0 0 2 0.5 2 3 2.2 3 5 0.9 5 2 4.4 2 1 0.8 1 2 1.6 2 0 0.0 0 1 0.3 1 3 2.2 3 4 0.8 4 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 2 1.5 3 3 0.6 4 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 2 1.5 2 2 0.4 2 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0

439 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 4 19.0 4 4 16.0 5 3 11.5 5 11 15.3 14 14 23.0 15 12 20.0 14 15 24.2 17 41 22.4 46 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 1 3.8 1 2 2.8 2 8 13.1 9 6 10.0 6 6 9.7 6 20 10.9 21 1 4.8 1 0 0.0 0 0 0.0 0 1 1.4 1 1 1.6 1 1 1.7 1 1 1.6 1 3 1.6 3 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 1 1.6 1 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 3 4.9 3 1 1.7 1 0 0.0 0 4 2.2 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 52 40.3 73 51 40.5 84 3 33.3 5 107 27.2 138 78 57.8 190 185 35.0 328 14 31.1 17 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 1 2.2 1 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 28 21.7 30 21 16.7 23 2 22.2 2 52 13.2 55 44 32.6 64 96 18.2 119 6 13.3 7 7 5.4 7 4 3.2 4 0 0.0 0 11 2.8 11 7 5.2 7 18 3.4 18 1 2.2 1 4 3.1 4 2 1.6 2 0 0.0 0 6 1.5 6 8 5.9 9 14 2.7 15 0 0.0 0 2 1.6 2 6 4.8 6 1 11.1 1 7 1.8 7 7 5.2 9 14 2.7 16 2 4.4 2 2 1.6 2 0 0.0 0 0 0.0 0 3 0.8 3 9 6.7 10 12 2.3 13 0 0.0 0

440 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 1 4.8 1 0 0.0 0 1 3.8 1 2 2.8 2 8 13.1 9 6 10.0 6 6 9.7 6 20 10.9 21 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 1 1.6 1 0 0.0 0 1 1.6 1 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 1 1.6 1 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 1 1.6 1 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.7 1 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 28 21.7 30 21 16.7 23 2 22.2 2 52 13.2 55 44 32.6 64 96 18.2 119 6 13.3 7 3 2.3 3 2 1.6 2 0 0.0 0 3 0.8 3 5 3.7 5 8 1.5 8 1 2.2 1 0 0.0 0 0 0.0 0 0 0.0 0 3 0.8 3 4 3.0 4 7 1.3 7 1 2.2 1 2 1.6 2 2 1.6 2 0 0.0 0 3 0.8 3 3 2.2 3 6 1.1 6 0 0.0 0 2 1.6 2 1 0.8 1 1 11.1 1 5 1.3 5 1 0.7 1 6 1.1 6 1 2.2 1 1 0.8 1 2 1.6 2 0 0.0 0 3 0.8 3 1 0.7 1 4 0.8 4 0 0.0 0 3 2.3 3 0 0.0 0 0 0.0 0 3 0.8 3 0 0.0 0 3 0.6 3 0 0.0 0 2 1.6 2 0 0.0 0 0 0.0 0 2 0.5 2 1 0.7 1 3 0.6 3 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 3 2.2 3 3 0.6 3 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 1 0.7 1 2 0.4 2 1 2.2 1 1 0.8 1 0 0.0 0 0 0.0 0 2 0.5 2 0 0.0 0 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 1.5 2 2 0.4 2 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0

441 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 1 4.8 1 0 0.0 0 1 3.8 1 2 2.8 2 8 13.1 9 6 10.0 6 6 9.7 6 20 10.9 21 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 0 0.0 0 1 1.4 1 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 0 0.0 0 1 1.4 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 28 21.7 30 21 16.7 23 2 22.2 2 52 13.2 55 44 32.6 64 96 18.2 119 6 13.3 7 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 36 27.9 39 22 17.5 28 0 0.0 0 38 9.7 41 34 25.2 53 72 13.6 94 10 22.2 10 17 13.2 17 11 8.7 13 0 0.0 0 18 4.6 18 16 11.9 17 34 6.4 35 5 11.1 5 7 5.4 7 11 8.7 11 0 0.0 0 7 1.8 7 7 5.2 8 14 2.7 15 2 4.4 2 4 3.1 4 2 1.6 2 0 0.0 0 5 1.3 5 5 3.7 6 10 1.9 11 1 2.2 1 3 2.3 3 1 0.8 1 0 0.0 0 3 0.8 3 3 2.2 5 6 1.1 8 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 3 2.2 4 4 0.8 5 0 0.0 0 2 1.6 2 0 0.0 0 0 0.0 0 2 0.5 2 1 0.7 1 3 0.6 3 1 2.2 1 1 0.8 1 1 0.8 1 0 0.0 0 1 0.3 1 2 1.5 3 3 0.6 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 1.5 2 2 0.4 2 0 0.0 0 2 1.6 2 0 0.0 0 0 0.0 0 2 0.5 2 0 0.0 0 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 1 2.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0

442 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 1 4.8 1 0 0.0 0 0 0.0 0 1 1.4 1 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 1 1.6 1 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 6 28.6 8 7 28.0 13 8 30.8 13 21 29.2 34 31 50.8 34 28 46.7 31 31 50.0 38 90 49.2 103 3 14.3 4 7 28.0 13 8 30.8 13 18 25.0 30 25 41.0 25 27 45.0 27 27 43.5 27 79 43.2 79 2 9.5 2 0 0.0 0 0 0.0 0 2 2.8 2 6 9.8 6 2 3.3 2 1 1.6 1 9 4.9 9 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.3 2 1 1.6 1 3 1.6 3 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.3 2 0 0.0 0 2 3.2 2 4 2.2 4 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 36 27.9 39 22 17.5 28 0 0.0 0 38 9.7 41 34 25.2 53 72 13.6 94 10 22.2 10 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 0.5 2 6 4.4 7 8 1.5 9 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 5 3.7 5 6 1.1 6 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 123 95.3 153 90 71.4 108 4 44.4 5 238 60.6 295 104 77.0 152 342 64.8 447 29 64.4 36 123 95.3 125 85 67.5 85 4 44.4 4 224 57.0 238 97 71.9 102 321 60.8 340 25 55.6 25 7 5.4 7 3 2.4 3 1 11.1 1 19 4.8 19 8 5.9 9 27 5.1 28 3 6.7 3 3 2.3 3 3 2.4 5 0 0.0 0 3 0.8 3 12 8.9 16 15 2.8 19 0 0.0 0 2 1.6 2 1 0.8 1 0 0.0 0 5 1.3 5 6 4.4 7 11 2.1 12 1 2.2 1 0 0.0 0 1 0.8 1 0 0.0 0 4 1.0 4 3 2.2 3 7 1.3 7 3 6.7 3 2 1.6 2 2 1.6 2 0 0.0 0 2 0.5 2 3 2.2 3 5 0.9 5 0 0.0 0 2 1.6 2 2 1.6 2 0 0.0 0 2 0.5 2 3 2.2 3 5 0.9 5 3 6.7 3 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 2 1.5 2 3 0.6 3 0 0.0 0

443 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 6 28.6 8 7 28.0 13 8 30.8 13 21 29.2 34 31 50.8 34 28 46.7 31 31 50.0 38 90 49.2 103 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 1 4.8 2 0 0.0 0 0 0.0 0 1 1.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 123 95.3 153 90 71.4 108 4 44.4 5 238 60.6 295 104 77.0 152 342 64.8 447 29 64.4 36 2 1.6 2 0 0.0 0 0 0.0 0 3 0.8 3 0 0.0 0 3 0.6 3 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 1 0.3 1 2 1.5 2 3 0.6 3 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 1 0.7 1 2 0.4 2 0 0.0 0 2 1.6 2 0 0.0 0 0 0.0 0 2 0.5 2 0 0.0 0 2 0.4 2 0 0.0 0 2 1.6 2 1 0.8 1 0 0.0 0 2 0.5 2 0 0.0 0 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 2 0 0.0 0 1 0.2 2 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0

444 1 mg 2 mg 4 mg 1 mg 2 mg 4 mg % % % % % % % % 6 28.6 8 7 28.0 13 8 30.8 13 21 29.2 34 31 50.8 34 28 46.7 31 31 50.0 38 90 49.2 103 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 9.5 2 2 8.0 4 3 11.5 3 7 9.7 9 5 8.2 7 6 10.0 6 3 4.8 3 14 7.7 16 0 0.0 0 2 8.0 2 3 11.5 3 5 6.9 5 1 1.6 1 4 6.7 4 0 0.0 0 5 2.7 5 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 1 1.6 1 0 0.0 0 1 1.6 1 2 1.1 2 2 9.5 2 0 0.0 0 0 0.0 0 2 2.8 2 2 3.3 2 0 0.0 0 0 0.0 0 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 1.6 1 0 0.0 0 0 0.0 0 1 0.5 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 3.3 2 0 0.0 0 2 1.1 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 mg 2 mg 4 2 mg 51 mg2 mg4 mg % % % % % % % 123 95.3 153 90 71.4 108 4 44.4 5 238 60.6 295 104 77.0 152 342 64.8 447 29 64.4 36 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 0 0.0 0 2 1.6 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 2.2 1 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 1 0.7 1 2 0.4 2 0 0.0 0 1 0.8 1 0 0.0 0 0 0.0 0 1 0.3 1 0 0.0 0 1 0.2 1 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 1 0.7 1 1 0.2 1 0 0.0 0 12 9.3 17 9 7.1 11 0 0.0 0 33 8.4 42 29 21.5 39 62 11.7 81 8 17.8 10 4 3.1 4 3 2.4 3 0 0.0 0 14 3.6 14 11 8.1 11 25 4.7 25 2 4.4 2 6 4.7 6 1 0.8 1 0 0.0 0 7 1.8 7 5 3.7 6 12 2.3 13 0 0.0 0 0 0.0 0 1 0.8 1 0 0.0 0 2 0.5 2 6 4.4 6 8 1.5 8 1 2.2 1 2 1.6 2 3 2.4 3 0 0.0 0 5 1.3 5 2 1.5 2 7 1.3 7 2 4.4 2 0 0.0 0 1 0.8 1 0 0.0 0 4 1.0 4 2 1.5 2 6 1.1 6 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 5 3.7 6 5 0.9 6 0 0.0 0 1 0.8 1 1 0.8 1 0 0.0 0 2 0.5 2 0 0.0 0 2 0.4 2 0 0.0 0 0 0.0 0 0 0.0 0 0 0.0 0 2 0.5 2 0 0.0 0 2 0.4 2 1 2.2 1 1 0.8 2 0 0.0 0 0 0.0 0 1 0.3 2 1 0.7 1 2 0.4 3 1 2.2 1