AUTONOMIC FUNCTIONAL STATE IN RENAL TUBERCULOSIS REPORT III. SERUM CHOLINESTERASE ACTIVITY IN RENAL TUBERCULOSIS Sanai Yamamura The Department of Urology, Kumamoto University College of Medicine (Director: Prof. K. Narahara) Activity of serum cholinesterase (abbreviated to ChE) was estimated on 14 unilateral renal tuberculosis patients (male: 10, female: 4, ages: 17-58), 5 tuberculous epididymitis (ages: 15-40) and 20 healthy persons (male: 9, female: 11, ages: 20-37) as the controle group by means of modified Michel's method. The results were as follows: 1) Serum ChE activity in healthy persons varied from 0.7 to 1.1 and had an average value of 0.860.06. 2) Serum ChE activity in renal tuberculosis patients varied from 0 to 1.1 and had an average value of 0.550.22. It was normal only in 21.4% of the patients and was extremely low (less than 0.3) in 42.9% of the patients. It seemed to decrease as a result of the influence of the destruction of tuberculous kidney, disturbance of the renal function, increase of the blood sedimentation rate and secondary disturbance of the liver function. 3) Three weeks after removal of the affected kidney, 64.3% of renal tuberculosis patients had normal activity of serum ChE and no case showed less than 0.3 of ChE activity. Parallel relation was observed between restoration of renal function and that of serum ChE activity. 4) Serum ChE activity of renal tuberculosis patients was not influenced by the injection of epinephrin, but apparently decreased by the injection of pilocarpin. 5) 40% of tuberculous epididymitis patients had normal activity of serum ChE and the remaining 60% of them showed a slight decrease of it. The average value was 0.760.17.
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