MJR-35 34 1 1 a MRICT b 2Beecham r-afs 3 4 20 4 mg/ 20 40 5 6 2 1 2 3 44 mg/ 5 6 7 8 4 Gn-RH 742
9 10 11 12 1 20 60 1 1MJR-351 mg/ 0.25 2 Lot. No. 2MJR-352 mg/ 1 1 Lot. No. 3MJR-354 mg/ 1 2 Lot. No. 2 MJR-35 1 1 mg2 mg 4 mg 24 MJR-35 1 mg/ 1 2 mg/ 2 mg/ 4 1 mg/ 1 0.25 mg 2 1 2 2 mg/ 1 1 1 1 2 4 mg/ 1 1 2 1 2 25 1 1 a 16 24 5 b 16 24 5 743
2 a 8 24 6 b 8 24 6 c 8 24 6 d 8 24 5 e 6 2 1 16 24 4 2 a b 3 CA602CA125 LHFSH CA602 744
4 Beecham MJR-35 1 2 3 3 3 4 19 19 745
.7-1 74 1 2 52 60 71 1 72 74 1 mg/ 21 2 mg/ 27 4 mg/ 26 72 2 1 mg/ 21 1 mg/ 0 2 mg/ 25 2 mg/ 2 4 mg/ 26 4 mg/ 0 71 1 1 mg/ 21 1 mg/ 0 2 mg/ 25 2 mg/ 0 4 mg/ 25 4 mg/ 1 60 11 1 mg/ 16 1 mg/ 5 2 mg/ 25 2 mg/ 0 4 mg/ 19 4 mg/ 6 52 8 1 mg/ 16 1 mg/ 0 2 mg/ 20 2 mg/ 5 4 mg/ 16 4 mg/ 3 * 1 746
1 72 12 8 2 mg/ 5 10 4 mg/ 3 9 2 mg/ 3 1 4 mg/ 1 11 1 mg/ 5 4 mg/ 6 2/3 1 mg/ 1 4 mg/ 1 1527 1 mg/ 1 4 mg/ 1 112 1 mg/ 1 4 mg/ 1 1 mg/ 1 4 mg/ 1 Beecham 1 mg/ 1 4 mg/ 1 4 mg/ 1 60 8 2 mg/ 5 4 mg/ 3 112 2 mg/ 2 4 mg/ 1 112 4 mg/ 1 112 Beecham 2 mg/ 1 112 2 mg/ 2 112 4 mg/ 1 4224 mg/ 1 42 CTD MJR-35.7-1 4 4 8 8 12 12 16 16 20 20 24 24 27 1 mg/ 0 1 0 0 0 7 13 21 2 mg/ 0 1 2 2 0 12 8 25 4 mg/ 0 3 0 1 0 10 11 25 0 5 2 3 0 29 32 71 747
3.7-2 1 mg/2 mg/4 mg/ 16 20 16 52 30 6 8 5 19 30 40 8 12 11 31 40 2 0 0 2 kg 50 6 6 7 19 50 60 7 11 7 25 60 1 2 0 3 2 1 2 5 1 3 2 6 0 0 0 0 6 7 6 19 9 10 6 25 0 0 2 2 2 2 3 7 3 2 4 9 5 8 4 17 4 6 3 13 2 2 2 6 4 5 5 14 5 4 3 12 3 6 2 11 3 5 6 14 1 0 0 1 Beecham 0 0 0 0 6 9 7 22 10 7 7 24 0 4 2 6 748
.7-3 24 1 mg/ 2 mg/ 4 62.5%10/16 90.0%18/20 81.3%13/16 1 mg/ 2 mg/ 4 mg/ 2 5 8 1 0 0 16 1 mg/ 12.5 43.8 8 5 7 0 0 0 20 16 2 mg/ 40.0 65.0 4 8 2 0 1 1 16 4 mg/ 25.0 75.0 2 8 5 1 0 0 16 1 mg/ 12.5 62.5 8 10 2 0 0 0 20 24 2 mg/ 40.0 90.0 5 7 1 1 0 1 15 4 mg/ 33.3 80.0 2 7 4 2 0 0 15 1 mg/ 13.3 60.0 7 10 2 0 1 0 20 2 mg/ 35.0 85.0 4 7 4 0 1 0 16 4 mg/ 25.0 68.8 2 8 5 1 0 0 16 1 mg/ 12.5 62.5 8 10 2 0 0 0 20 2 mg/ 40.0 90.0 5 8 1 1 0 1 16 4 mg/ 31.3 81.3 % 24 1 mg/ 2 mg/ 4 mg/ 56.3%9/16 72.0%18/25 63.2%12/19.7-4 24 1 mg/ 2 4 mg/ 66.7%10/15 76.5%13/17 92.9%13/14 749
4 1 4 5 0 14 2 1 mg/ 28.6 35.7 3 1 4 4 3 15 5 8 2 mg/ 20.0 26.7 1 1 2 5 5 14 2 4 mg/ 7.1 14.3 5 2 5 2 0 14 2 1 mg/ 35.7 50.0 5 1 5 2 2 15 5 16 2 mg/ 33.3 40.0 4 4 1 0 1 10 6 4 mg/ 40.0 80.0 4 4 3 3 1 15 1 1 mg/ 26.7 53.3 7 2 3 1 1 14 6 24 2 mg/ 50.0 64.3 4 3 1 0 1 9 6 4 mg/ 44.4 77.8 3 3 3 3 1 13 2 1 mg/ 23.1 46.2 8 1 2 1 1 13 7 2 mg/ 61.5 69.2 2 2 3 2 1 10 6 4 mg/ 20.0 40.0 4 4 3 3 1 15 1 1 mg/ 26.7 53.3 7 2 3 1 1 14 6 2 mg/ 50.0 64.3 4 3 2 0 1 10 6 4 mg/ 40.0 70.0 0 0 3 3 3 9 7 1 mg/ 0.0 0.0 4 1 3 3 1 12 8 8 2 mg/ 33.3 41.7 1 2 4 2 2 11 5 4 mg/ 9.1 27.3 1 0 4 1 2 8 8 1 mg/ 12.5 12.5 6 1 3 1 1 12 8 16 2 mg/ 50.0 58.3 4 3 2 0 0 9 7 4 mg/ 44.4 77.8 0 2 2 2 0 6 10 1 mg/ 0.0 33.3 7 2 2 0 1 12 8 24 2 mg/ 58.3 75.0 4 3 0 1 0 8 7 4 mg/ 50.0 87.5 1 1 2 2 3 9 6 1 mg/ 11.1 22.2 7 2 1 1 1 12 8 2 mg/ 58.3 75.0 2 3 2 2 0 9 7 4 mg/ 22.2 55.6 0 2 2 2 0 6 10 1 mg/ 0.0 33.3 7 2 2 0 1 12 8 2 mg/ 58.3 75.0 4 3 1 1 0 9 7 4 mg/ 44.4 77.8 % 750
1 0 2 1 1 5 11 1 mg/ 20.0 20.0 3 1 1 4 2 11 9 8 2 mg/ 27.3 36.4 1 0 2 0 0 3 13 4 mg/ 33.3 33.3 2 0 1 0 1 4 12 1 mg/ 50.0 50.0 6 0 1 2 0 9 11 16 2 mg/ 66.7 66.7 2 0 1 0 0 3 13 4 mg/ 66.7 66.7 2 0 1 0 1 4 12 1 mg/ 50.0 50.0 7 2 0 0 1 10 10 24 2 mg/ 70.0 90.0 1 0 0 0 1 2 13 4 mg/ 50.0 50.0 2 0 1 0 1 4 11 1 mg/ 50.0 50.0 6 2 0 1 1 10 10 2 mg/ 60.0 80.0 2 0 0 0 1 3 13 4 mg/ 66.7 66.7 2 0 1 0 1 4 12 1 mg/ 50.0 50.0 7 2 0 0 1 10 10 2 mg/ 70.0 90.0 2 0 0 0 1 3 13 4 mg/ 66.7 66.7 2 1 4 1 1 9 7 1 mg/ 22.2 33.3 1 3 2 5 0 11 4 8 2 mg/ 9.1 36.4 1 2 0 2 0 5 8 4 mg/ 20.0 60.0 4 1 3 0 0 8 8 1 mg/ 50.0 62.5 4 3 2 1 0 10 4 16 2 mg/ 40.0 70.0 2 3 1 0 1 7 7 4 mg/ 28.6 71.4 5 1 2 0 0 8 8 1 mg/ 62.5 75.0 4 5 2 0 0 11 5 24 2 mg/ 36.4 81.8 3 2 0 0 0 5 8 4 mg/ 60.0 100.0 3 2 2 1 0 8 7 1 mg/ 37.5 62.5 4 5 4 0 0 13 5 2 mg/ 30.8 69.2 3 1 1 1 0 6 8 4 mg/ 50.0 66.7 5 1 2 0 0 8 8 1 mg/ 62.5 75.0 4 5 2 0 0 11 5 2 mg/ 36.4 81.8 3 2 1 0 0 6 8 4 mg/ 50.0 83.3 % 751
2 4 4 3 1 14 2 1 mg/ 14.3 42.9 5 1 6 5 0 17 3 8 2 mg/ 29.4 35.3 2 3 2 6 0 13 3 4 mg/ 15.4 38.5 5 4 2 2 1 14 2 1 mg/ 35.7 64.3 7 6 3 1 0 17 3 16 2 mg/ 41.2 76.5 4 7 2 0 0 13 3 4 mg/ 30.8 84.6 9 2 1 1 0 13 3 1 mg/ 69.2 84.6 10 4 2 1 0 17 3 24 2 mg/ 58.8 82.4 6 5 1 0 0 12 3 4 mg/ 50.0 91.7 8 1 1 2 0 12 3 1 mg/ 66.7 75.0 9 4 2 1 0 16 3 2 mg/ 56.3 81.3 5 4 3 1 0 13 3 4 mg/ 38.5 69.2 9 2 1 1 0 13 3 1 mg/ 69.2 84.6 10 4 2 1 0 17 3 2 mg/ 58.8 82.4 6 6 1 0 0 13 3 4 mg/ 46.2 92.3 3 1 9 1 1 15 1 1 mg/ 20.0 26.7 4 3 4 6 0 17 3 8 2 mg/ 23.5 41.2 1 2 9 2 2 16 0 4 mg/ 6.3 18.8 3 5 6 1 0 15 1 1 mg/ 20.0 53.3 6 4 6 1 0 17 3 16 2 mg/ 35.3 58.8 5 9 0 0 1 15 1 4 mg/ 33.3 93.3 4 6 4 1 0 15 1 1 mg/ 26.7 66.7 7 6 4 0 0 17 3 24 2 mg/ 41.2 76.5 6 6 1 0 0 13 2 4 mg/ 46.2 92.3 4 4 2 4 0 14 1 1 mg/ 28.6 57.1 8 6 2 1 0 17 3 2 mg/ 47.1 82.4 5 5 3 1 1 15 1 4 mg/ 33.3 66.7 4 6 4 1 0 15 1 1 mg/ 26.7 66.7 7 6 4 0 0 17 3 2 mg/ 41.2 76.5 6 7 1 0 0 14 2 4 mg/ 42.9 92.9 % 752
.7-5 24 1 mg/ 2 mg/ 4 mg/ 42.9%6/14 72.2%13/18 46.2%6/13 3 2 5 4 0 14 2 1 mg/ 21.4 35.7 5 0 6 7 0 18 2 8 2 mg/ 27.8 27.8 1 1 4 7 0 13 3 4 mg/ 7.7 15.4 5 2 6 1 0 14 2 1 mg/ 35.7 50.0 5 4 6 3 0 18 2 16 2 mg/ 27.8 50.0 1 3 5 4 0 13 3 4 mg/ 7.7 30.8 4 2 7 1 0 14 2 1 mg/ 28.6 42.9 10 3 5 0 0 18 2 24 2 mg/ 55.6 72.2 4 2 4 2 0 12 3 4 mg/ 33.3 50.0 5 1 5 2 0 13 2 1 mg/ 38.5 46.2 8 4 5 0 0 17 2 2 mg/ 47.1 70.6 3 2 5 3 0 13 3 4 mg/ 23.1 38.5 4 2 7 1 0 14 2 1 mg/ 28.6 42.9 10 3 5 0 0 18 2 2 mg/ 55.6 72.2 4 2 5 2 0 13 3 4 mg/ 30.8 46.2 % 753
.7-6 24 1 mg/ 2 mg/ 4 mg/ 16.7%2/12 66.7%10/15 36.4%4/11 % 1 0 3 8 0 12 4 1 mg/ 8.3 8.3 2 0 1 12 0 15 5 8 2 mg/ 13.3 13.3 0 1 7 3 0 11 5 4 mg/ 0.0 9.1 1 1 5 5 0 12 4 1 mg/ 8.3 16.7 2 1 8 4 0 15 5 16 2 mg/ 13.3 20.0 0 2 6 3 0 11 5 4 mg/ 0.0 18.2 2 0 7 3 0 12 4 1 mg/ 16.7 16.7 3 7 4 1 0 15 5 24 2 mg/ 20.0 66.7 0 4 4 2 0 10 5 4 mg/ 0.0 40.0 3 0 4 4 0 11 4 1 mg/ 27.3 27.3 2 6 5 1 0 14 5 2 mg/ 14.3 57.1 0 4 4 3 0 11 5 4 mg/ 0.0 36.4 2 0 7 3 0 12 4 1 mg/ 16.7 16.7 3 7 4 1 0 15 5 2 mg/ 20.0 66.7 0 4 5 2 0 11 5 4 mg/ 0.0 36.4 754
8 24 24.7-7 2 6 5 2 0 15 0 1 mg/ 13.3 53.3 6 3 8 2 0 19 1 2 mg/ 31.6 47.4 4 3 4 5 0 16 0 4 mg/ 25.0 43.8 6 1 2 4 1 14 1 1 mg/ 42.9 50.0 5 5 4 2 1 17 3 2 mg/ 29.4 58.8 2 3 1 6 0 12 4 4 mg/ 16.7 41.7 4 0 0 1 1 6 9 1 mg/ 66.7 66.7 4 3 0 2 0 9 11 2 mg/ 44.4 77.8 4 0 1 1 1 7 9 4 mg/ 57.1 57.1 1 1 0 2 1 5 10 1 mg/ 20.0 40.0 7 1 0 1 1 10 10 2 mg/ 70.0 80.0 3 0 1 1 0 5 11 4 mg/ 60.0 60.0 2 1 0 2 3 8 7 1 mg/ 25.0 37.5 6 2 0 1 1 10 10 2 mg/ 60.0 80.0 1 1 0 0 1 3 13 4 mg/ 33.3 66.7 2 6 3 4 0 15 0 1 mg/ 13.3 53.3 7 4 7 1 1 20 0 2 mg/ 35.0 55.0 3 6 1 5 1 16 0 4 mg/ 18.8 56.3 % 755
.7-8 24 1 mg/ 2 mg/ 4 mg/ 33.3%2/6 57.1%4/7 75.0%6/8 1 mg/ 2 mg/ 4 mg/ 66.7%2/3 50.0%4/8 83.3%5/6 1 2 1 1 5 11 1 mg/ 20.0 3 2 0 2 7 13 8 2 mg/ 42.9 4 2 0 1 7 9 4 mg/ 57.1 2 1 1 2 6 10 1 mg/ 33.3 5 1 0 1 7 13 16 2 mg/ 71.4 4 2 0 1 7 8 4 mg/ 57.1 2 2 1 1 6 10 1 mg/ 33.3 4 1 0 2 7 13 24 2 mg/ 57.1 5 1 0 1 7 7 4 mg/ 71.4 2 2 1 1 6 10 1 mg/ 33.3 4 1 0 2 7 13 2 mg/ 57.1 6 1 0 1 8 7 4 mg/ 75.0 1 1 0 1 3 13 1 mg/ 33.3 2 3 2 2 9 11 8 2 mg/ 22.2 3 1 1 1 6 10 4 mg/ 50.0 2 0 0 2 4 12 1 mg/ 50.0 4 3 0 1 8 12 16 2 mg/ 50.0 3 1 0 1 5 10 4 mg/ 60.0 2 0 0 1 3 13 1 mg/ 66.7 4 3 0 1 8 12 24 2 mg/ 50.0 5 0 0 1 6 8 4 mg/ 83.3 2 0 0 1 3 13 1 mg/ 66.7 4 3 0 1 8 12 2 mg/ 50.0 5 0 0 1 6 9 4 mg/ 83.3 % 756
.7-9 24 1 mg/ 2 mg/ 4 mg/ 25.0%1/4 0.0%0/3 33.3%1/3 0 3 0 2 5 11 1 mg/ 0.0 0 0 0 4 4 16 8 2 mg/ 0.0 1 0 0 2 3 13 4 mg/ 33.3 0 3 0 2 5 11 1 mg/ 0.0 0 0 0 3 3 17 16 2 mg/ 0.0 0 0 0 3 3 12 4 mg/ 0.0 1 2 0 1 4 12 1 mg/ 25.0 0 0 0 3 3 17 24 2 mg/ 0.0 1 0 0 1 2 12 4 mg/ 50.0 1 2 0 1 4 12 1 mg/ 25.0 0 0 0 3 3 17 2 mg/ 0.0 1 0 0 2 3 12 4 mg/ 33.3 % 1 mg/ 2 mg/ 4 mg/ 28.6%2/7 50.0%2/4 0.0%0/3 757
1 mg/ 16 2 4 24 1 2 mg/ 4 mg/.7-10 4 1 mg/ 10 1 5 16 2 mg/ 17 0 3 20 4 mg/ 13 0 3 16 8 1 mg/ 14 0 2 16 2 mg/ 17 0 3 20 4 mg/ 15 0 1 16 12 1 mg/ 14 0 2 16 2 mg/ 18 0 2 20 4 mg/ 16 0 0 16 16 1 mg/ 14 0 2 16 2 mg/ 19 0 1 20 4 mg/ 16 0 0 16 20 1 mg/ 15 0 1 16 2 mg/ 18 0 2 20 4 mg/ 15 0 0 15 24 1 mg/ 14 1 1 16 2 mg/ 18 0 2 20 4 mg/ 15 0 0 15 2 mg/.7-11 1 mg/ 4 mg/ 2 758
7 2 9 2 0 20 4 8 6 4 2 0 20 8 8 5 7 0 0 20 12 10 6 3 1 0 20 16 10 9 1 0 0 20 20 14 5 1 0 0 20 24 13 6 1 0 0 20 15 3 1 1 0 20 24 13 6 1 0 0 20 8 3 7 2 0 20 4 11 4 4 1 0 20 8 12 5 1 2 0 20 12 13 5 2 0 0 20 16 14 4 1 1 0 20 20 14 4 1 1 0 20 24 15 4 1 0 0 20 15 3 2 0 0 20 15 4 24 1 0 0 20 11 3 3 3 0 20 4 10 6 3 1 0 20 8 12 5 2 1 0 20 12 15 3 2 0 0 20 16 17 3 0 0 0 20 20 17 3 0 0 0 20 24 19 1 0 0 0 20 18 1 1 0 0 20 19 1 24 0 0 0 20 5 4 4 4 1 18 4 4 5 3 3 0 15 8 6 5 4 0 0 15 12 8 4 2 0 0 14 16 10 4 0 0 0 14 20 13 3 0 0 0 16 24 13 2 1 0 0 16 13 4 1 0 0 18 13 2 24 1 0 0 16 3 1 5 10 1 20 4 4 3 8 4 1 20 8 8 3 7 1 1 20 12 9 5 5 0 1 20 16 12 6 1 0 1 20 20 13 3 3 1 0 20 24 14 3 3 0 0 20 13 3 3 0 0 19 14 3 24 3 0 0 20 3 0 7 10 0 20 4 3 5 7 5 0 20 8 7 3 8 2 0 20 12 9 4 7 0 0 20 16 9 7 4 0 0 20 20 11 4 5 0 0 20 24 10 8 2 0 0 20 11 6 3 0 0 20 10 8 24 2 0 0 20 759
2 mg/.7-12 1 mg/ 4 mg/ 2 mg/ 2 2 8 6 2 20 4 4 4 7 4 1 20 8 7 1 8 4 0 20 12 7 4 5 3 0 19 16 7 6 6 1 0 20 20 7 9 2 1 0 19 24 10 9 1 0 0 20 8 10 1 0 0 19 24 10 9 1 0 0 20 5 4 6 5 0 20 4 6 4 6 4 0 20 8 7 3 6 4 0 20 12 8 4 4 3 0 19 16 8 6 5 1 0 20 20 8 9 1 1 0 19 24 11 8 1 0 0 20 9 9 1 0 0 19 24 11 8 1 0 0 20 760
CA602 MJR-35 LH2.2916.93 miu/mlfsh3.0114.72 miu/ml 1182 pg/ml 1.7 ng/ml 761
LH FSH.7-2 762
1 mg 2 mg 4 mg.7-3 763
CA602 1 mg 2 mg 63 U/mL 4 mg gdl.7-4 CA602 UmL gdl CA602 UmL gdl CA602 UmL 764
24 1 mg/ 2 mg/ 4 mg/ 100%21/21 76.0%19/25 76.0%19/25 4 1 mg/ 2 mg/ 4 mg/ 21 13 61.9% 24 25 17 68.0% 33 26 13 50.0% 32.7-13 3% 3 25.0% 11.1% 6.9% 5.6% 5.6% 4.2%.7-14.7-16 1 mg/ 10 16 6 8 0 0 2 mg/ 10 21 7 11 1 1 4 mg/ 9 19 6 12 1 1 2 mg/ 2254 mg/ 419 1 40 84 1 6 2 2 1 2122 mg/ 1 1 2252 mg/.7-20.7-22p.773774 765
1 mg/ 2 mg/ 4 mg/ 21 25 26 72 13 17 13 43 % 61.9 68.0 50.0 59.7 24 33 32 89 0 5 3 8 * SOC PT % % % 0 0.0 0 1 4.0 1 1 3.8 1 2 2.8 2 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 2 7.7 4 2 2.8 4 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 3 14.3 5 4 16.0 4 2 7.7 2 9 12.5 11 3 14.3 5 1 4.0 1 0 0.0 0 4 5.6 6 0 0.0 0 0 0.0 0 2 7.7 2 2 2.8 2 0 0.0 0 3 12.0 3 0 0.0 0 3 4.2 3 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 2 9.5 2 1 4.0 1 1 3.8 1 4 5.6 4 2 9.5 2 1 4.0 1 1 3.8 1 4 5.6 4 4 19.0 4 4 16.0 5 3 11.5 5 11 15.3 14 1 4.8 1 0 0.0 0 1 3.8 1 2 2.8 2 2 9.5 2 3 12.0 4 3 11.5 3 8 11.1 9 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 1 4.8 1 1 4.0 1 0 0.0 0 2 2.8 2 1 4.8 1 0 0.0 0 1 3.8 1 2 2.8 2 1 4.8 1 0 0.0 0 0 0.0 0 1 1.4 1 0 0.0 0 0 0.0 0 1 3.8 1 1 1.4 1 % 1 4.8 1 0 0.0 0 0 0.0 0 1 1.4 1 1 4.8 1 0 0.0 0 0 0.0 0 1 1.4 1 6 28.6 8 7 28.0 13 8 30.8 13 21 29.2 34 3 14.3 4 7 28.0 13 8 30.8 13 18 25.0 30 2 9.5 2 0 0.0 0 0 0.0 0 2 2.8 2 1 4.8 2 0 0.0 0 0 0.0 0 1 1.4 2 2 9.5 2 2 8.0 4 3 11.5 3 7 9.7 9 0 0.0 0 2 8.0 2 3 11.5 3 5 6.9 5 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 2 9.5 2 0 0.0 0 0 0.0 0 2 2.8 2 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 1 4.8 1 5 20.0 5 1 3.8 1 7 9.7 7 *MedDRA/J Ver.8.1 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 0 0.0 0 1 4.0 1 1 3.8 1 2 2.8 2 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 γ 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 1 4.8 1 0 0.0 0 0 0.0 0 1 1.4 1 0 0.0 0 1 4.0 1 0 0.0 0 1 1.4 1 766
- - - 21 10 6 0 13 % 47.6 28.6 0.0 61.9 16 8 0 24 % % % % 2 9.5 3 2 9.5 2 0 0.0 0 3 14.3 5 2 9.5 3 2 9.5 2 0 0.0 0 3 14.3 5 0 0.0 0 2 9.5 2 0 0.0 0 2 9.5 2 0 0.0 0 2 9.5 2 0 0.0 0 2 9.5 2 3 14.3 3 1 4.8 1 0 0.0 0 4 19.0 4 2 9.5 2 0 0.0 0 0 0.0 0 2 9.5 2 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 5 23.8 6 2 9.5 2 0 0.0 0 6 28.6 8 2 9.5 2 2 9.5 2 0 0.0 0 3 14.3 4 2 9.5 2 0 0.0 0 0 0.0 0 2 9.5 2 1 4.8 2 0 0.0 0 0 0.0 0 1 4.8 2 2 9.5 2 0 0.0 0 0 0.0 0 2 9.5 2 2 9.5 2 0 0.0 0 0 0.0 0 2 9.5 2 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 *MedDRA/J Ver.8.1 PT - - - 25 10 7 1 17 % 40.0 28.0 4.0 68.0 21 11 1 33 % % % % 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 3 12.0 3 1 4.0 1 0 0.0 0 4 16.0 4 2 8.0 2 1 4.0 1 0 0.0 0 3 12.0 3 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 3 12.0 4 1 4.0 1 0 0.0 0 4 16.0 5 2 8.0 3 1 4.0 1 0 0.0 0 3 12.0 4 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 3 12.0 5 4 16.0 7 1 4.0 1 7 28.0 13 3 12.0 5 4 16.0 7 1 4.0 1 7 28.0 13 2 8.0 4 0 0.0 0 0 0.0 0 2 8.0 4 2 8.0 2 0 0.0 0 0 0.0 0 2 8.0 2 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 3 12.0 3 2 8.0 2 0 0.0 0 5 20.0 5 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 γ 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 *MedDRA/J Ver.8.1 PT 767
- - - 26 9 6 1 13 % 34.6 23.1 3.8 50.0 19 12 1 32 % % % % 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 1 3.8 1 1 3.8 2 1 3.8 1 2 7.7 4 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 1 3.8 1 1 3.8 1 0 0.0 0 2 7.7 2 1 3.8 1 1 3.8 1 0 0.0 0 2 7.7 2 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 2 7.7 3 2 7.7 2 0 0.0 0 3 11.5 5 2 7.7 2 1 3.8 1 0 0.0 0 3 11.5 3 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 6 23.1 9 3 11.5 4 0 0.0 0 8 30.8 13 6 23.1 9 3 11.5 4 0 0.0 0 8 30.8 13 3 11.5 3 0 0.0 0 0 0.0 0 3 11.5 3 3 11.5 3 0 0.0 0 0 0.0 0 3 11.5 3 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 *MedDRA/J Ver.8.1 PT 72 1 1.4% 1 4 mg/ 405 72 8 11.1% 19 2 mg/ 25 5 20.0% 10 4 mg/ 26 3 11.5% 9 2 mg/ 225 1.7-17 768
* / MedDRA/J Ver.8.1 PT 202 46 2 mg 31 19 97 28 120 213 30 2 mg 85 50 43 54 1 73 1 50 43 26 61 216 42 2 mg 91 30 69 218 42 2 mg 59 54 8 223 37 4 mg 31 29 70 19 80 225 46 2 mg 84 40 406 27 4 mg 53 7 48 419 36 4 mg 50 29 28 29 28 29 28 29 28 29 28 29 28 * 1 PTAPTTTAT PT 4 mg/ 1 2 4 1 mg/ 2 mg/ 4 1 113 20 116 16 2 mg/ 208 8 16 227 8 APTT 4 mg/ 1 2 MJR-35 7 1 mg/ 2 mg/ 7 1 mg/ 113 20 116 16 222 4 2 mg/ 208 8 16 211 8 227 8 228 4 TAT 1 mg/ 2 mg/ 4 16 16 401 16 20 402 404 405 812 407 409 24 410 248 411 481624 412 769
24 413 1220 416 20 417 12 418 12 423 424 12 425 16.7-23.7-25P.775784 1 mg/ 1 2 mg/ γ- 1 1 2 mg/ 4 mg/ 1 2 mg/ 1 202 57.0 kg 28 58.5 kg 35 61.0 kg 5 4.0 kg 19 31 4 56.0 kg 4 mg/ 1 402 54.0 kg 111 57.2 kg 58.7 kg 4 61.6 kg 5 24 4 28 2 8 12 770
1 mg/ 1 20 20.7-18 6 6 5 2 2 21 1 mg/ 28.6 28.6 23.8 9.5 9.5 10 8 6 1 0 25 4 2 mg/ 40.0 32.0 24.0 4.0 0.0 7 7 9 1 1 25 4 mg/ 28.0 28.0 36.0 4.0 4.0 2 8 9 2 0 21 1 mg/ 9.5 38.1 42.9 9.5 0.0 2 12 9 1 0 24 8 2 mg/ 8.3 50.0 37.5 4.2 0.0 1 12 8 1 0 22 4 mg/ 4.5 54.5 36.4 4.5 0.0 2 12 4 2 0 20 1 mg/ 10.0 60.0 20.0 10.0 0.0 6 12 3 2 0 23 12 2 mg/ 26.1 52.2 13.0 8.7 0.0 1 15 5 0 1 22 4 mg/ 4.5 68.2 22.7 0.0 4.5 4 9 6 1 0 20 1 mg/ 20.0 45.0 30.0 5.0 0.0 6 9 3 2 0 20 16 2 mg/ 30.0 45.0 15.0 10.0 0.0 5 10 5 1 0 21 4 mg/ 23.8 47.6 23.8 4.8 0.0 11 4 4 1 0 20 1 mg/ 55.0 20.0 20.0 5.0 0.0 3 15 2 0 0 20 20 2 mg/ 15.0 75.0 10.0 0.0 0.0 7 9 4 0 0 20 4 mg/ 35.0 45.0 20.0 0.0 0.0 6 10 4 0 0 20 1 mg/ 30.0 50.0 20.0 0.0 0.0 6 9 5 0 0 20 24 2 mg/ 30.0 45.0 25.0 0.0 0.0 5 11 4 0 0 20 4 mg/ 25.0 55.0 20.0 0.0 0.0 % 8 12.7-19 771
90% 10% 1 mg/ 21 6.5 1.7 7 7 5 2 mg/ 25 5.5 1.2 7 5 4 4 mg/ 25 6.4 1.9 8 6 5 1 mg/ 21 5.8 6.2 10 6 0 4 2 mg/ 25 4.2 5.3 13 1 0 4 mg/ 25 10.6 9.3 23 10 0 1 mg/ 21 15.5 8.9 28 15 2 8 2 mg/ 24 15.6 9.3 28 13.5 3 4 mg/ 22 15.1 10.2 28 12.5 2 1 mg/ 20 9.9 7.3 21.5 8.5 1.5 12 2 mg/ 23 12.7 10.1 27 14 0 4 mg/ 21 16.1 11.7 28 19 2 1 mg/ 20 10.8 8.2 21 10 0 16 2 mg/ 20 10.9 10.9 27.5 10 0 4 mg/ 21 11.2 10.0 25 9 0 1 mg/ 20 6.9 9.1 18.5 0 0 20 2 mg/ 20 9.9 8.5 25 9 0 4 mg/ 20 11.7 11.3 27 12 0 1 mg/ 20 5.3 5.6 12 4.5 0 24 2 mg/ 20 9.0 9.3 23 6.5 0 4 mg/ 20 10.4 10.9 28 5.5 0 1 mg/ 20 6.1 1.8 8.5 6 4.5 2 mg/ 23 5.4 1.2 7 5 4 4 mg/ 24 6.0 2.1 8 6 3 MJR-35 1 mg/ 2 mg/ 4 mg/ 1 mg/ 2 mg/ 4 21 13 61.9%25 17 68.0%26 13 50.0% 772
- - - - 21 0 8 4 3 13 % 0.0 38.1 19.0 14.3 61.9 0 14 6 4 24 % % % % % 0 0.0 0 3 14.3 5 0 0.0 0 0 0.0 0 3 14.3 5 0 0.0 0 3 14.3 5 0 0.0 0 0 0.0 0 3 14.3 5 0 0.0 0 0 0.0 0 1 4.8 1 1 4.8 1 2 9.5 2 0 0.0 0 0 0.0 0 1 4.8 1 1 4.8 1 2 9.5 2 0 0.0 0 3 14.3 3 1 4.8 1 0 0.0 0 4 19.0 4 0 0.0 0 2 9.5 2 0 0.0 0 0 0.0 0 2 9.5 2 0 0.0 0 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 0 0.0 0 0 0.0 0 0 0.0 0 1 4.8 1 1 4.8 1 0 0.0 0 0 0.0 0 0 0.0 0 1 4.8 1 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 0 0.0 0 3 14.3 4 1 4.8 2 2 9.5 2 6 28.6 8 0 0.0 0 0 0.0 0 1 4.8 2 2 9.5 2 3 14.3 4 0 0.0 0 2 9.5 2 0 0.0 0 0 0.0 0 2 9.5 2 0 0.0 0 1 4.8 2 0 0.0 0 0 0.0 0 1 4.8 2 0 0.0 0 1 4.8 1 1 4.8 1 0 0.0 0 2 9.5 2 0 0.0 0 1 4.8 1 1 4.8 1 0 0.0 0 2 9.5 2 0 0.0 0 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 0 0.0 0 1 4.8 1 0 0.0 0 0 0.0 0 1 4.8 1 *MedDRA/J Ver.8.1 PT - - - - 25 1 6 7 6 17 % 4.0 24.0 28.0 24.0 68.0 1 8 18 6 33 * % % % % % 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 1 4.0 1 3 12.0 3 0 0.0 0 0 0.0 0 4 16.0 4 1 4.0 1 2 8.0 2 0 0.0 0 0 0.0 0 3 12.0 3 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 3 12.0 4 0 0.0 0 4 16.0 5 0 0.0 0 1 4.0 1 2 8.0 3 0 0.0 0 3 12.0 4 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 7 6 24.0 6 7 28.0 13 0 0.0 0 0 0.0 0 1 4.0 7 6 24.0 6 7 28.0 13 0 0.0 0 1 4.0 2 1 4.0 2 0 0.0 0 2 8.0 4 0 0.0 0 1 4.0 1 1 4.0 1 0 0.0 0 2 8.0 2 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 2 8.0 2 3 12.0 3 0 0.0 0 5 20.0 5 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 γ 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 1 4.0 1 0 0.0 0 0 0.0 0 1 4.0 1 *MedDRA/J Ver.8.1 PT 773
- - - - 26 0 1 7 7 13 % 0.0 3.8 26.9 26.9 50.0 0 2 22 8 32 * % % % % % 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 2 7.7 4 0 0.0 0 2 7.7 4 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 1 3.8 1 2 7.7 2 0 0.0 0 0 0.0 0 1 3.8 1 1 3.8 1 2 7.7 2 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 2 1 3.8 2 1 3.8 1 3 11.5 5 0 0.0 0 1 3.8 1 1 3.8 1 1 3.8 1 3 11.5 3 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 2 7.7 7 6 23.1 6 8 30.8 13 0 0.0 0 0 0.0 0 2 7.7 7 6 23.1 6 8 30.8 13 0 0.0 0 0 0.0 0 3 11.5 3 0 0.0 0 3 11.5 3 0 0.0 0 0 0.0 0 3 11.5 3 0 0.0 0 3 11.5 3 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 0 0.0 0 0 0.0 0 1 3.8 1 0 0.0 0 1 3.8 1 *MedDRA/J Ver.8.1 PT 774
8 16 24 0/21 0/20 0/19 0/19 0/19 /µl *1 /mm 3 *2 > *1 35009100 2/21 4/20 2/19 2/19 2/19 *2 < 40008000 % 9.5 20.0 10.5 10.5 10.5 0/21 1/20 0/19 2/19 0/19 % > % 0.0 5.0 0.0 10.5 0.0 *1 06 0/21 0/20 1/19 0/19 0/19 *2 < 15 % 0.0 0.0 5.3 0.0 0.0 5/21 2/20 2/19 0/19 3/19 % > % 23.8 10.0 10.5 0.0 15.8 *1 06 0/21 0/20 1/19 1/19 0/19 *2 < 36 % 0.0 0.0 5.3 5.3 0.0 0/21 1/20 1/19 1/19 1/19 % > % 0.0 5.0 5.3 5.3 5.3 *1 3273 1/21 2/20 0/19 0/19 1/19 < *2 4555 % 4.8 10.0 0.0 0.0 5.3 1/21 1/20 2/19 1/19 2/19 % > % 4.8 5.0 10.5 5.3 10.5 *1 02 0/21 0/20 0/19 0/19 0/19 *2 < 01 0/21 1/20 1/19 0/19 0/19 % > % 0.0 5.0 5.3 0.0 0.0 *1 08 1/21 0/20 0/19 0/19 1/19 < *2 47 % 4.8 0.0 0.0 0.0 5.3 1/21 1/20 0/19 0/19 0/19 % > % 4.8 5.0 0.0 0.0 0.0 *1 1859 0/21 1/20 1/19 0/19 0/19 *2 < 2545 % 0.0 5.0 5.3 0.0 0.0 0/21 0/20 0/19 0/19 0/19 10000/µL *1 10000/mm 3*2 > *1 13.036.9 1/21 0/20 0/19 1/19 0/19 *2 < 13.033.0 % 4.8 0.0 0.0 5.3 0.0 1/21 2/20 2/19 2/19 0/19 10000/µL *1 10000/mm 3*2 > % 4.8 10.0 10.5 10.5 0.0 *1 376500 0/21 1/20 2/19 1/19 1/19 *2 < 370490 % 0.0 5.0 10.5 5.3 5.3 0/21 1/20 1/19 0/19 0/19 g/dl > % 0.0 5.0 5.3 0.0 0.0 *1 11.315.2 1/21 3/20 3/19 1/19 3/19 *2 < 11.516.0 % 4.8 15.0 15.8 5.3 15.8 4/21 3/20 4/19 4/19 3/19 % > % 19.0 15.0 21.1 21.1 15.8 *1 33.444.9 1/21 0/20 0/19 0/19 1/19 *2 < 33.047.0 % 4.8 0.0 0.0 0.0 5.3 0/21 1/20 1/19 2/19 0/19 > g/dl % 0.0 5.0 5.3 10.5 0.0 *1 6.88.2 0/21 2/20 1/19 1/19 3/19 < *2 6.58.2 % 0.0 10.0 5.3 5.3 15.8 0/21 0/20 0/19 0/19 0/19 > g/dl *1 4.05.0 2/21 0/20 0/19 0/19 0/19 < *2 3.65.5 % 9.5 0.0 0.0 0.0 0.0 0/21 1/20 1/19 1/19 0/19 A/G > % 0.0 5.0 5.3 5.3 0.0 *1 1.32.0 3/21 1/20 1/19 2/19 1/19 *2 1.52.6 < % 14.3 5.0 5.3 10.5 5.3 GOT 0/21 0/20 0/19 0/19 0/19 > IU/L *1 1040 0/21 0/20 0/19 0/19 0/19 < *2 740 775
8 16 24 GPT 0/21 0/20 0/19 0/19 0/19 > IU/L *1 540 1/21 0/20 0/19 0/19 0/19 < *2 035 % 4.8 0.0 0.0 0.0 0.0 γ-gtp 0/21 0/20 0/19 0/19 0/19 > IU/L *1 50 0/21 0/20 0/19 0/19 0/19 *2 < 040 ALP 0/21 0/20 0/19 0/19 0/19 > IU/L *1 80260 0/21 2/20 4/19 2/19 0/19 *2 < 85300 % 0.0 10.0 21.1 10.5 0.0 LDH 1/21 0/20 0/19 1/19 0/19 > IU/L % 4.8 0.0 0.0 5.3 0.0 *1 230460 1/21 0/20 0/19 0/19 1/19 < *2 100225 % 4.8 0.0 0.0 0.0 5.3 1/21 1/20 0/19 0/19 0/19 mg/dl > % 4.8 5.0 0.0 0.0 0.0 *1 0.21.0 0/21 0/20 0/19 0/19 0/19 *2 < 0.21.2 2/21 0/20 0/19 1/19 1/19 mg/dl > % 9.5 0.0 0.0 5.3 5.3 *1 150219 4/21 4/20 6/19 2/19 1/19 *2 < 120220 % 19.0 20.0 31.6 10.5 5.3 HDL-C 1/21 1/20 0/19 2/19 1/19 > mg/dl % 4.8 5.0 0.0 10.5 5.3 *1 39.093.0 0/21 0/20 0/19 0/19 0/19 *2 < 3680 β- 0/21 0/20 0/19 0/19 0/19 > mg/dl *1 190500 2/21 3/20 2/19 2/19 1/19 < *2 290655 % 9.5 15.0 10.5 10.5 5.3 BUN 0/21 1/20 0/19 0/19 1/19 > mg/dl % 0.0 5.0 0.0 0.0 5.3 *1 620 1/21 0/20 1/19 0/19 1/19 *2 < 820 % 4.8 0.0 5.3 0.0 5.3 0/21 0/20 0/19 0/19 0/19 mg/dl > *1 0.61.3 0/21 0/20 0/19 0/19 0/19 *2 < 0.51.0 0/21 0/20 1/19 1/19 1/19 > mg/dl % 0.0 0.0 5.3 5.3 5.3 *1 2.55.4 0/21 1/20 1/19 2/19 0/19 *2 < 2.76.3 % 0.0 5.0 5.3 10.5 0.0 Ca 0/21 0/20 0/19 1/19 0/19 > mg/dl % 0.0 0.0 0.0 5.3 0.0 *1 8.710.1 1/21 4/20 0/19 2/19 1/19 *2 < 8.810.5 % 4.8 20.0 0.0 10.5 5.3 P 0/21 0/20 0/19 0/19 0/19 > mg/dl *1 2.44.3 0/21 1/20 0/19 1/19 1/19 *2 < 2.54.5 % 0.0 5.0 0.0 5.3 5.3 Na 0/21 0/20 0/19 0/19 0/19 > meq/l *1 137145 0/21 0/20 1/19 0/19 0/19 *2 < 135145 % 0.0 0.0 5.3 0.0 0.0 776
8 16 24 K 2/21 0/20 0/19 0/19 1/19 > meq/l % 9.5 0.0 0.0 0.0 5.3 *1 3.34.8 0/21 0/20 0/19 0/19 0/19 < *2 3.44.9 Cl 1/21 0/20 0/19 0/19 0/19 > meq/l % 4.8 0.0 0.0 0.0 0.0 *1 99107 0/21 0/20 0/19 0/19 1/19 *2 < 98108 % 0.0 0.0 0.0 0.0 5.3 2/21 0/18 0/19 0/19 0/18 > % 9.5 0.0 0.0 0.0 0.0 *1, *2-0/21 0/18 0/19 0/19 0/18 < 0/21 0/18 0/19 0/19 0/18 > *1, *2-0/21 0/18 0/19 0/19 0/18 < 0/21 0/18 0/19 0/19 0/18 > *1 ± 0/21 0/18 0/19 0/19 0/18 *2 - < 1/21 0/19 0/19 1/19 0/19 > mg/dl % 4.8 0.0 0.0 5.3 0.0 *1 200400 3/21 7/19 4/19 6/19 6/19 *2 < 150340 % 14.3 36.8 21.1 31.6 31.6 0/21 0/19 0/19 0/19 1/19 > % % 0.0 0.0 0.0 0.0 5.3 *1 75125 1/21 0/19 1/19 1/19 1/19 *2 < 80120 % 4.8 0.0 5.3 5.3 5.3 PT 0/21 0/19 1/19 0/19 0/19 > sec. % 0.0 0.0 5.3 0.0 0.0 *1 1013 1/21 1/19 2/19 6/19 6/19 *2 < 10.514.0 % 4.8 5.3 10.5 31.6 31.6 APTT 5/21 1/19 2/19 2/19 0/19 > sec. % 23.8 5.3 10.5 10.5 0.0 *1 2540 0/21 0/19 0/19 0/19 0/19 *2 < 2840 AT- 0/21 0/19 0/19 0/19 0/19 > % *1 79121 0/21 0/19 1/19 0/19 0/19 *2 < 80125 % 0.0 0.0 5.3 0.0 0.0 1/21 0/18 0/19 0/19 0/18 > % 4.8 0.0 0.0 0.0 0.0 mol/molcre *1, 0/21 0/18 0/19 0/19 0/18 *2 1336 < 0/21 0/18 1/19 0/19 0/18 > % 0.0 0.0 5.3 0.0 0.0 mol/molcre *1, 0/21 0/18 0/19 0/19 0/18 *2 7 < 1/21 0/18 0/19 1/19 0/18 NTx > % 4.8 0.0 0.0 5.3 0.0 nmbce/mmcre 0/21 0/18 0/19 0/19 0/18 *1,*2 8.369.9 < *1 A *2 A 777
8 16 24 0/25 0/24 1/21 1/20 1/22 /µl *1 /mm 3 *2 > % 0.0 0.0 4.8 5.0 4.5 *1 35009100 1/25 2/24 0/21 0/20 3/22 *2 < 40008000 % 4.0 8.3 0.0 0.0 13.6 1/25 1/23 1/21 0/19 1/21 % > % 4.0 4.3 4.8 0.0 4.8 *1 06 0/25 0/23 0/21 1/19 1/21 *2 < 15 % 0.0 0.0 0.0 5.3 4.8 2/25 1/23 3/21 7/19 12/21 % > % 8.0 4.3 14.3 36.8 57.1 *1 06 0/25 0/23 1/21 0/19 0/21 *2 < 36 % 0.0 0.0 4.8 0.0 0.0 2/25 1/23 1/21 1/19 1/21 % > % 8.0 4.3 4.8 5.3 4.8 *1 3273 2/25 0/23 1/21 0/19 0/21 < *2 4555 % 8.0 0.0 4.8 0.0 0.0 1/25 1/23 0/21 1/19 1/21 % > % 4.0 4.3 0.0 5.3 4.8 *1 02 0/25 0/23 0/21 0/19 0/21 *2 < 01 2/25 0/23 2/21 3/19 7/21 % > % 8.0 0.0 9.5 15.8 33.3 *1 08 0/25 1/23 0/21 1/19 0/21 < *2 47 % 0.0 4.3 0.0 5.3 0.0 1/25 0/23 1/21 0/19 0/21 % > % 4.0 0.0 4.8 0.0 0.0 *1 1859 1/25 1/23 1/21 1/19 1/21 *2 < 2545 % 4.0 4.3 4.8 5.3 4.8 2/25 3/24 0/21 1/20 0/22 10000/µL *1 10000/mm 3*2 > % 8.0 12.5 0.0 5.0 0.0 *1 13.036.9 0/25 2/24 0/21 0/20 0/22 *2 < 13.033.0 % 0.0 8.3 0.0 0.0 0.0 0/25 1/24 1/21 2/20 0/22 10000/µL *1 10000/mm 3*2 > % 0.0 4.2 4.8 10.0 0.0 *1 376500 1/25 2/24 0/21 0/20 0/22 *2 < 370490 % 4.0 8.3 0.0 0.0 0.0 0/25 0/24 0/21 0/20 0/22 g/dl > *1 11.315.2 1/25 4/24 1/21 2/20 2/22 *2 < 11.516.0 % 4.0 16.7 4.8 10.0 9.1 1/25 4/24 3/21 4/20 1/22 % > % 4.0 16.7 14.3 20.0 4.5 *1 33.444.9 1/25 2/24 0/21 0/20 0/22 *2 < 33.047.0 % 4.0 8.3 0.0 0.0 0.0 0/25 1/24 0/21 0/20 0/22 > g/dl % 0.0 4.2 0.0 0.0 0.0 *1 6.88.2 2/25 1/24 3/21 1/20 5/22 *2 < 6.58.2 % 8.0 4.2 14.3 5.0 22.7 0/25 0/24 0/21 0/20 0/22 > g/dl *1 4.05.0 0/25 0/24 0/21 0/20 3/22 *2 < 3.65.5 % 0.0 0.0 0.0 0.0 13.6 1/25 1/24 1/21 1/20 1/22 A/G > % 4.0 4.2 4.8 5.0 4.5 *1 1.32.0 0/25 2/24 1/21 1/20 1/22 *2 1.52.6 < % 0.0 8.3 4.8 5.0 4.5 GOT 0/25 0/24 0/21 0/20 0/22 > IU/L *1 1040 0/25 0/24 0/21 0/20 0/22 *2 < 740 778
8 16 24 GPT 0/25 0/24 0/21 0/20 0/22 > IU/L *1 540 1/25 0/24 0/21 0/20 0/22 *2 < 035 % 4.0 0.0 0.0 0.0 0.0 γ-gtp 1/25 1/24 1/21 1/20 1/22 > IU/L % 4.0 4.2 4.8 5.0 4.5 *1 50 0/25 0/24 0/21 0/20 0/22 *2 < 040 ALP 0/25 0/24 0/21 0/20 0/22 > IU/L *1 80260 1/25 1/24 0/21 1/20 0/22 *2 < 85300 % 4.0 4.2 0.0 5.0 0.0 LDH 0/25 1/24 2/21 1/20 0/22 > IU/L % 0.0 4.2 9.5 5.0 0.0 *1 230460 1/25 0/24 0/21 0/20 0/22 *2 < 100225 % 4.0 0.0 0.0 0.0 0.0 1/25 1/24 1/21 1/20 1/22 mg/dl > % 4.0 4.2 4.8 5.0 4.5 *1 0.21.0 0/25 0/24 0/21 1/20 0/22 *2 < 0.21.2 % 0.0 0.0 0.0 5.0 0.0 6/25 4/24 2/21 1/20 2/22 mg/dl > % 24.0 16.7 9.5 5.0 9.1 *1 150219 2/25 4/24 2/21 3/20 2/22 *2 < 120220 % 8.0 16.7 9.5 15.0 9.1 HDL-C 0/25 0/24 0/21 0/20 0/22 > mg/dl *1 39.093.0 2/25 2/24 1/21 2/20 3/22 *2 < 3680 % 8.0 8.3 4.8 10.0 13.6 β- 1/25 0/24 1/21 0/20 1/22 > mg/dl % 4.0 0.0 4.8 0.0 4.5 *1 190500 0/25 2/24 2/21 0/20 1/22 < *2 290655 % 0.0 8.3 9.5 0.0 4.5 BUN 0/25 0/24 0/21 0/20 0/22 > mg/dl *1 620 0/25 0/24 0/21 1/20 0/22 *2 < 820 % 0.0 0.0 0.0 5.0 0.0 0/25 0/24 1/21 0/20 0/22 > mg/dl % 0.0 0.0 4.8 0.0 0.0 *1 0.61.3 0/25 0/24 0/21 0/20 1/22 *2 < 0.51.0 % 0.0 0.0 0.0 0.0 4.5 1/25 0/24 0/21 1/20 0/22 > mg/dl % 4.0 0.0 0.0 5.0 0.0 *1 2.55.4 4/25 4/24 3/21 1/20 1/22 *2 < 2.76.3 % 16.0 16.7 14.3 5.0 4.5 Ca 0/25 0/24 0/21 0/20 0/22 > mg/dl *1 8.710.1 1/25 3/24 2/21 2/20 2/22 *2 < 8.810.5 % 4.0 12.5 9.5 10.0 9.1 P 0/25 0/24 1/21 0/20 0/22 > mg/dl % 0.0 0.0 4.8 0.0 0.0 *1 2.44.3 2/25 1/24 2/21 0/20 0/22 *2 < 2.54.5 % 8.0 4.2 9.5 0.0 0.0 Na 0/25 0/24 0/21 0/20 0/22 > meq/l *1 137145 1/25 0/24 0/21 0/20 1/22 *2 < 135145 % 4.0 0.0 0.0 0.0 4.5 779
8 16 24 K 1/25 0/24 1/21 0/20 1/22 > meq/l % 4.0 0.0 4.8 0.0 4.5 *1 3.34.8 0/25 0/24 0/21 0/20 0/22 < *2 3.44.9 Cl 0/25 1/24 1/21 0/20 0/22 > meq/l % 0.0 4.2 4.8 0.0 0.0 *1 99107 0/25 0/24 1/21 0/20 2/22 *2 < 98108 % 0.0 0.0 4.8 0.0 9.1 1/25 0/22 0/21 3/20 1/22 > % 4.0 0.0 0.0 15.0 4.5 *1, *2-0/25 0/22 0/21 0/20 0/22 < 0/25 0/22 0/21 0/20 0/22 > *1, *2-0/25 0/22 0/21 0/20 0/22 < 0/25 0/22 0/21 0/20 0/22 > *1 ± 0/25 0/22 0/21 0/20 0/22 *2 - < 1/25 1/24 0/21 0/20 0/22 > mg/dl % 4.0 4.2 0.0 0.0 0.0 *1 200400 4/25 7/24 9/21 5/20 11/22 *2 < 150340 % 16.0 29.2 42.9 25.0 50.0 0/25 0/24 0/21 0/20 0/21 > % *1 75125 1/25 1/24 0/21 0/20 0/21 *2 < 80120 % 4.0 4.2 0.0 0.0 0.0 PT 0/25 2/24 1/21 0/20 0/22 > sec. % 0.0 8.3 4.8 0.0 0.0 *1 1013 9/25 5/24 5/21 4/20 8/22 *2 < 10.514.0 % 36.0 20.8 23.8 20.0 36.4 APTT 2/25 3/24 2/21 1/20 2/22 > sec. % 8.0 12.5 9.5 5.0 9.1 *1 2540 0/25 0/24 0/21 0/20 0/22 *2 < 2840 AT- 0/25 0/24 1/21 1/20 0/21 > % % 0.0 0.0 4.8 5.0 0.0 *1 79121 1/25 0/24 0/21 0/20 0/21 *2 < 80125 % 4.0 0.0 0.0 0.0 0.0 2/25 0/22 1/21 4/20 4/22 > % 8.0 0.0 4.8 20.0 18.2 mol/molcre *1, 0/25 0/22 0/21 0/20 0/22 *2 1336 < 1/25 0/22 1/21 2/20 1/22 > % 4.0 0.0 4.8 10.0 4.5 mol/molcre *1, 0/25 0/22 0/21 0/20 0/22 *2 7 < 0/25 0/22 0/21 0/20 1/22 NTx > % 0.0 0.0 0.0 0.0 4.5 nmbce/mmcre *1, 1/25 0/22 0/21 0/20 0/22 *2 8.369.9 < % 4.0 0.0 0.0 0.0 0.0 *1 A *2 A 780
8 16 24 3/26 0/22 0/21 0/20 0/23 /µl *1 /mm 3 *2 > % 11.5 0.0 0.0 0.0 0.0 *1 35009100 0/26 0/22 0/21 1/20 0/23 *2 < 40008000 % 0.0 0.0 0.0 5.0 0.0 4/25 0/22 3/21 3/20 2/23 % > % 16.0 0.0 14.3 15.0 8.7 *1 06 0/25 0/22 0/21 0/20 0/23 *2 < 15 10/25 1/22 0/21 0/20 0/23 % > % 40.0 4.5 0.0 0.0 0.0 *1 06 0/25 0/22 0/21 0/20 0/23 *2 < 36 0/25 0/22 0/21 0/20 0/23 % > *1 3273 0/25 2/22 1/21 1/20 0/23 < *2 4555 % 0.0 9.1 4.8 5.0 0.0 3/25 3/22 2/21 1/20 3/23 % > % 12.0 13.6 9.5 5.0 13.0 *1 02 0/25 0/22 0/21 0/20 0/23 *2 < 01 4/25 2/22 0/21 0/20 0/23 % > % 16.0 9.1 0.0 0.0 0.0 *1 08 0/25 0/22 0/21 0/20 0/23 < *2 47 0/25 2/22 2/21 0/20 0/23 % > % 0.0 9.1 9.5 0.0 0.0 *1 1859 0/25 0/22 0/21 0/20 0/23 *2 < 2545 0/26 1/22 0/21 0/20 0/23 10000/µL *1 10000/mm 3*2 > % 0.0 4.5 0.0 0.0 0.0 *1 13.036.9 0/26 0/22 0/21 1/20 0/23 *2 < 13.033.0 % 0.0 0.0 0.0 5.0 0.0 0/26 0/22 1/21 2/20 1/23 10000/µL *1 10000/mm 3*2 > % 0.0 0.0 4.8 10.0 4.3 *1 376500 1/26 1/22 0/21 0/20 2/23 *2 < 370490 % 3.8 4.5 0.0 0.0 8.7 0/26 0/22 1/21 0/20 1/23 g/dl > % 0.0 0.0 4.8 0.0 4.3 *1 11.315.2 3/26 1/22 1/21 1/20 2/23 *2 < 11.516.0 % 11.5 4.5 4.8 5.0 8.7 0/26 0/22 2/21 1/20 1/23 % > % 0.0 0.0 9.5 5.0 4.3 *1 33.444.9 1/26 1/22 1/21 0/20 0/23 *2 < 33.047.0 % 3.8 4.5 4.8 0.0 0.0 1/26 0/23 3/21 0/20 1/23 > g/dl % 3.8 0.0 14.3 0.0 4.3 *1 6.88.2 3/26 1/23 0/21 0/20 1/23 *2 < 6.58.2 % 11.5 4.3 0.0 0.0 4.3 0/26 1/23 1/21 0/20 1/23 > g/dl % 0.0 4.3 4.8 0.0 4.3 *1 4.05.0 0/26 0/23 0/21 1/20 0/23 *2 < 3.65.5 % 0.0 0.0 0.0 5.0 0.0 1/25 1/23 2/21 1/20 1/23 A/G > % 4.0 4.3 9.5 5.0 4.3 *1 1.32.0 2/25 0/23 1/21 1/20 1/23 *2 1.52.6 < % 8.0 0.0 4.8 5.0 4.3 GOT 1/26 0/23 0/21 0/20 0/23 > IU/L % 3.8 0.0 0.0 0.0 0.0 *1 1040 0/26 0/23 0/21 0/20 0/23 *2 < 740 781
8 16 24 GPT 0/26 0/23 0/21 0/20 0/23 IU/L > *1 540 0/26 0/23 0/21 0/20 0/23 *2 < 035 γ-gtp 2/26 1/23 1/21 1/20 1/23 > IU/L % 7.7 4.3 4.8 5.0 4.3 *1 50 0/26 0/23 0/21 0/20 0/23 *2 < 040 ALP 0/26 0/23 0/21 0/20 0/23 > IU/L *1 80260 2/26 2/23 2/21 2/20 1/23 *2 < 85300 % 7.7 8.7 9.5 10.0 4.3 LDH 1/26 0/23 0/21 1/20 0/23 > IU/L % 3.8 0.0 0.0 5.0 0.0 *1 230460 1/26 0/23 0/21 0/20 0/23 *2 < 100225 % 3.8 0.0 0.0 0.0 0.0 1/26 0/23 0/21 0/20 0/23 mg/dl > % 3.8 0.0 0.0 0.0 0.0 *1 0.21.0 0/26 0/23 0/21 0/20 0/23 *2 < 0.21.2 1/26 0/23 1/21 0/20 1/23 mg/dl > % 3.8 0.0 4.8 0.0 4.3 *1 150219 7/26 4/23 7/21 6/20 4/23 *2 < 120220 % 26.9 17.4 33.3 30.0 17.4 HDL-C 0/26 0/23 0/21 0/20 0/23 > mg/dl *1 39.093.0 0/26 1/23 1/21 0/20 0/23 *2 < 3680 % 0.0 4.3 4.8 0.0 0.0 β- 0/25 0/23 0/21 0/20 0/23 > mg/dl *1 190500 2/25 4/23 4/21 5/20 4/23 < *2 290655 % 8.0 17.4 19.0 25.0 17.4 BUN 0/26 0/23 2/21 0/20 0/23 > mg/dl % 0.0 0.0 9.5 0.0 0.0 *1 620 1/26 1/23 1/21 1/20 2/23 *2 < 820 % 3.8 4.3 4.8 5.0 8.7 0/26 0/23 0/21 0/20 0/23 mg/dl > *1 0.61.3 0/26 0/23 0/21 0/20 0/23 *2 < 0.51.0 0/26 0/23 0/21 0/20 0/23 > mg/dl *1 2.55.4 4/26 1/23 1/21 2/20 1/23 *2 < 2.76.3 % 15.4 4.3 4.8 10.0 4.3 Ca 0/26 0/23 0/21 0/20 0/23 > mg/dl *1 8.710.1 1/26 0/23 0/21 2/20 1/23 *2 < 8.810.5 % 3.8 0.0 0.0 10.0 4.3 P 2/26 0/23 0/21 0/20 1/23 > mg/dl % 7.7 0.0 0.0 0.0 4.3 *1 2.44.3 0/26 0/23 0/21 1/20 0/23 *2 < 2.54.5 % 0.0 0.0 0.0 5.0 0.0 Na 0/26 0/23 0/21 0/20 0/23 > meq/l *1 137145 0/26 1/23 2/21 1/20 0/23 *2 < 135145 % 0.0 4.3 9.5 5.0 0.0 782
8 16 24 K 2/26 3/23 2/21 2/20 2/23 > meq/l % 7.7 13.0 9.5 10.0 8.7 *1 3.34.8 0/26 0/23 0/21 0/20 0/23 *2 < 3.44.9 Cl 0/26 0/23 1/21 0/20 0/23 > meq/l % 0.0 0.0 4.8 0.0 0.0 *1 99107 0/26 0/23 0/21 0/20 0/23 *2 < 98108 5/25 1/22 0/20 1/20 1/22 > % 20.0 4.5 0.0 5.0 4.5 *1, *2-0/25 0/22 0/20 0/20 0/22 < 1/25 1/22 0/20 0/20 0/22 > % 4.0 4.5 0.0 0.0 0.0 *1, *2-0/25 0/22 0/20 0/20 0/22 < 0/25 0/22 0/20 0/20 0/22 > *1 ± 0/25 0/22 0/20 0/20 0/22 *2 - < 2/26 0/23 0/21 0/20 0/23 mg/dl > % 7.7 0.0 0.0 0.0 0.0 *1 200400 6/26 6/23 7/21 5/20 9/23 *2 < 150340 % 23.1 26.1 33.3 25.0 39.1 1/26 0/23 0/21 0/20 0/23 > % % 3.8 0.0 0.0 0.0 0.0 *1 75125 1/26 1/23 0/21 1/20 2/23 *2 < 80120 % 3.8 4.3 0.0 5.0 8.7 PT 0/26 0/23 0/21 0/20 0/23 > sec. *1 1013 6/26 1/23 1/21 1/20 3/23 *2 < 10.514.0 % 23.1 4.3 4.8 5.0 13.0 APTT 1/26 1/23 0/21 0/20 0/23 > sec. % 3.8 4.3 0.0 0.0 0.0 *1 2540 0/26 0/23 0/21 0/20 0/23 < *2 2840 AT- 0/26 3/23 1/21 2/20 0/23 > % % 0.0 13.0 4.8 10.0 0.0 *1 79121 0/26 0/23 0/21 1/20 0/23 < *2 80125 % 0.0 0.0 0.0 5.0 0.0 C % *1, *2 55140 C % *1, *2 70150 S % *1, *2 60150 S % *1, *2 65135 1/24 1/23 1/21 1/20 0/23 > % 4.2 4.3 4.8 5.0 0.0 0/24 0/23 0/21 0/20 0/23 < 0/24 0/23 1/21 0/20 0/23 > % 0.0 0.0 4.8 0.0 0.0 0/24 0/23 1/21 2/20 1/23 < % 0.0 0.0 4.8 10.0 4.3 0/24 0/23 0/21 0/20 0/23 > 1/24 0/23 0/21 1/20 1/23 < % 4.2 0.0 0.0 5.0 4.3 0/24 0/23 0/21 0/20 0/23 > 1/24 0/23 1/21 0/20 3/23 < % 4.2 0.0 4.8 0.0 13.0 783
TAT ng/ml *1 03.0 *2 03.0 PIC µg/ml *1 00.8 00.8 *2 NTx nmbce/mmcre *1, *2 8.369.9 8 16 24 16/24 3/23 3/21 3/20 5/23 > % 6.7 13.0 14.3 15.0 21.7 0/24 0/23 0/21 0/20 0/23 < 2/24 2/23 1/21 0/20 1/23 > % 8.3 8.7 4.8 0.0 4.3 0/24 0/23 0/21 0/20 0/23 < 1/25 1/22 1/20 0/20 1/22 > % 4.0 4.5 5.0 0.0 4.5 0/25 0/22 0/20 0/20 0/22 < 0/25 0/22 1/20 1/20 0/22 > % 0.0 0.0 5.0 5.0 0.0 0/25 0/22 0/20 0/20 0/22 < 0/25 0/22 0/20 0/20 0/22 > 0/25 0/22 0/20 1/20 0/22 < % 0.0 0.0 0.0 5.0 0.0 mol/molcre *1, *2 1336 mol/molcre *1, *2 7 *1 A *2 A 784
BBT 4 4 1 BBT BBT BBT 4 24 6 BBT 4 28 BBT BBT 1 2 3BBT BBT BBT 52 1 mg/ 2 mg/ 4 mg/ 16 20 16 BBT 49 15 18 16 BBT 3 1 2 0 2 1 mg/ 2 mg/ 1 BBT. -1 785
49 1 37 11. -1 1 1 mg/ 222 4. -1 4 BBT BBT 4 16 26 1.7 ng/ml 14 33 0.2 ng/ml 0.3 ng/ml 37 1 mg/ 2 mg/ 4 10 14 13 30 BBT. -2 7 BBT. -3 17 BBT. -4 1.5 ng/ml 11 4 4 3 BBT 1.0 ng/ml 3 BBT 2 1 mg/ 1 1042 mg/ 1 209 BBT 1 2 mg/ 224 16 BBT 104 16 20 24 2 1.7 ng/ml 24 28 5 0.4 ng/ml 786
209 0.5 ng/ml BBT 1 2 mg 224 0.7 ng/ml BBT BBT 1 MJR-35 2 4 BBT MJR-35 BBT BBT BBT 8 2 4 MJR-35 16 1 2 mg21 MJR-35 BBT 2.7.2.231a BBT. -5 BBT BBT 0.7 ng/ml BBT MJR-35 2 mg/ BBT 2, 3 787
MJR-35 1 mg 16 2 MJR-35 2 mg 4 mg BBT. -2 BBT 1.7 ng/ml B.T. 37.40 37.30 37.20 37.10 37.00 36.90 36.80 36.70 36.60 36.50 36.40 10 9 8 7 6 5 4 3 ng/ml B.T. P 36.30 2 36.20 36.10 1 36.00-26 -19-12 -5 2 9 16 23 30 37 44 51 58 0 788
B.T. 37.40 37.30 37.20 37.10 37.00 36.90 36.80 36.70 36.60 36.50 36.40 ng/ml B.T. P 36.30 36.20 36.10 36.00-28 -21-14 -7 0 7 14 21 28 35 42 49 56 B.T. 37.50 37.40 37.30 37.20 37.10 37.00 36.90 36.80 36.70 36.60 36.50 36.40 ng/ml B.T. P 36.30 36.20 36.10 36.00 82 89 96 103 789
B.T. 37.50 37.40 37.30 37.20 37.10 37.00 36.90 36.80 36.70 36.60 36.50 36.40 10 9 8 7 6 5 4 3 ng/ml B.T. P 36.30 2 36.20 36.10 1 36.00 28 35 42 49 0 B.T. 37.00 36.90 36.80 36.70 36.60 36.50 36.40 36.30 36.20 36.10 30 25 20 15 10 ng/ml B.T. P 36.00 5 35.90 35.80-29 -22-15 -8-1 6 13 20 27 34 41 0 790
1 mg/ BBT BBT 4812162024 102 24A 104 24C 105 24A 106 24A 107 24A 108 24A 109 24A 110 24A 111 24A 112 24A 113 24A 115 24A 117 24A 118 24B 120 24A 222 24B 2 mg/ BBT BBT 4812162024 121 24A 201 24B 203 24A 204 24A 205 24A 206 24B 207 24B 208 24B 209 24C 210 24A 211 24A 212 24A 214 24B 215 24A 217 24A 221 24A 224 16 2024 B 226 24A 227 24B 228 24A 4 mg/ BBT BBT 4812162024 402 24A 403 24A 404 24A 407 24A 408 24B 409 24A 410 24A 412 24A 414 24A 415 24A 416 24A 417 16 B 418 24A 420 24A 421 24A 424 24B BBT A B C BBT 791