Candida albicans In Vitro Diagnostics (13)--D-Glucan Determination Reagents

D 012

Candida albicans In Vitro Diagnostics (13)--D-Glucan Determination Reagents

DATA : 1 DATA : 2 3 DATA : UNGITEC 1

1 DATA : 20pg/mL 1020pg/mL 10pg/mL (cut off 20pg/mL) 90.2%(37/41) 100%(85/85) 96.8%(122/126) 2 1000 100 20 10 1 (13)--D(pg/mL)

FUNGITEC 3

DATA : 2 1. Candida albicans 2. Candida glabrata 3. Candida parapsilosis 4. Candida tropicalis 5. Candida guilliermondii 6. Aspergillus fumigatus 7. Aspergillus flavus 8. Aspergillus niger 9. Cryptococcus neoformans 10. Mucor sp. 11. Trichosporon beigelii 100 100 90 80 73.8 70 64.3 60 50 45.7 40 30 30.2 20 10 0 10.0 5.2 3.7 1.7 01145111219202930394054556465 4

FUNGITEC 5

DATA : 3 525.6 pg/ml Cryptococcus neoformans C. neoformans 19871112 (C) 39 38 37 1 5 10 15 20 25 30 5 10 15 20 25 30 100 50 0 525.6 459.2 (mg dl 1 ) 3.8 7.9 4.4 10.4 10.1 10.7 2.2 0.2 0.9 0.7 Pseudomonas aeruginosa 76.5 pg/ml 1987345 10 15 20 25 30 1 5 10 15 20 25 30 1 5 (C) 39 38 37 (pg ml 1 ) 100 80 60 40 20 0 76.5 (mg dl 1 ) (mm h 1 ) 0.0 0.9 12.1 8.2 5.1 3.1 0.4 0.3 0.2 0.1 0.2 0.0 6 99 107 102 94 50 32 31 17 10 6

FUNGITEC L2, Ph1, HL-4Extremely high risk group minor-bcr HL-4 VP-16Ara-C 34.2 pg /ml20 pg /ml 56 1 5 10 15 20 25 30 1 5 10 15 20 25 30 B 3g/ 200mg 300mg 140mg/kg 100mg 140mg/kg 100mg/kg 140mg/kg 6mg/kg 2T 30mg/kg 200mg/kg 25mg/kg 30mg () 40 39 38 37 36 60 52.2 30 34.2 25.8 18.6 0 100 100 100 100 200 500 1400 1800 3500 14,300 18,400 1500 1800 1500 (mg dl 1 ) 2.0 15.8 22.6 16.2 23.4 19.4 18.2 20.0 18.6 17.2 2.5 0.3 0.0 0.1 0 0 0 0 2 6.0 7.0 20.0 45.0 75.0 85.0 16.0 19.0 14.0 200mg 400mg 200mg 56 14 20 25 31 5 10 17 12 20 31 10 20 30 200mg/ B 15 20 25 30 4g/ 2g/ 400mg/ 2g/ 400mg/ 400mg/ 6g/ 400mg/ 4g/ 200mg/ 2g/ 400mg/ 4g/ 400mg / 400mg/ 400mg/ 160mg/ 20mg/ 400mg/ 2mg/ G-CSF 300g/300g/150g /75g / 2mg/ 300mg/ 10mg/ G-CSF 300g / 180mg/ 4g/ 0.3g/ () 40 39 38 37 36 (mg dl 1 ) 9.1 9.6 18.0 18.1 14.9 11.4 9.2 6.0 5.0 10.7 10.5 16.5 14.1 4 5.6 11.5 7.9 3.0 0.4 35.5pg/mL 91.9pg/mL 42.35pg/mL 30.43pg/mL 7

FUNGITEC (pg ml 1 ) 300 G test/es 200 100 0 CT 6/1 6 30 7/14 15 16 21 26 8/2 3 9 17 20 26 9/16 24 29 C. tropicalis C. tropicalis C. tropicalis C. tropicalis G test Es Candida tropicalis C. tropicalis C. tropicaliscandida Candida Candida albicans Aspergillus flavus Aspergillus fumigatus Cryptococcus neoformans Microsporum canis Trichophyton mentagrophytes Trichophyton rubrum Saccharomyces cerevisiae Staphylococcus epidermidis Staphylococcus aureus -Streptococcus hemolyticus 8

R R 9

10 R R R R R

D01228 28 1921 2325 0227001 D01228 250 R D01219 160 D01221 180 D01223 200 D01225 220 11

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100-0005 6-1 Telephone:03-5220-8953 Facsimile :03-5220-8956 E-mail : lal@seikagaku.co.jp URL : http://www.seikagaku.co.jp 2005. 6. 2T(U)