pp Helicobacter Pylori 1997 pp DIC/TTP. DIC ology 1997 pp Etoh T, Kato J, Washimine H, Imamura T, Kitamur
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1 1. Eto T, Kitamura K: Adrenomedullin: Hormone or Paracrine Factor?, in Fabrini A and Santiemma B (eds): Internal Medicine and Endocrinology: Pathophysiological and Clinical Interactions, Centro Stampa d'ateneo, Roma, 1997, pp pp pp pp (CGRP) 1997 pp PAMP 1997 pp pp KEY WORD pp pp
2 pp Helicobacter Pylori 1997 pp DIC/TTP. DIC ology 1997 pp Etoh T, Kato J, Washimine H, Imamura T, Kitamura K, Koiwaya Y, Kangawa K, Eto T: Plasma proadrenomedullin N-terminal 20 peptide (PAMP) in patients with congestive heart failure. Horm Metab Res 29: 46-47, Etoh T, Doi H, Hanada Y, Kato J, Imamura T, Kitamura K, Koiwaya Y, Eto T: Cardiac secretion of adrenomedullin by percutaneous transluminal coronary angioplasty. Horm Metab Res 29: , Fukuoka S, Hayashida K, Hirose Y, Shimotsu Y, Ishida Y, Kakuchi H, Eto T: Use of iodine-123 metaiodobenzylguanidine myocardial imaging to predict the effectiveness of β-blocker therapy in patients with dilated cardiomyopathy. Eur J Nucl Med 24: , Hara S, Asada Y, Hatakeyama K, Marutsuka K, Sato Y, Kisanuki A, Sumiyoshi A: Expression of tissue factor and tissue factor pathway inhibitor in rat lungs with lipopolysaccharide-induced disseminated intravascular coagulation. Lab Invest 77: , Higa A, Eto T, Nawa Y: Evaluation of the role of neutrophils in the pathogenesis of acetic acid-induced colitis in mice. Scand J Gastroenterol 32: , Ishikawa N, Wakelin D, Mahida YR: Role of T helper 2 cells in intestinal goblet cell hyperplasia in mice infected with Trichinella spiralis. Gastroenterology 113: ,
3 7. Ishihara T, Kato J, Kitamura K, Katoh F, Fujimoto S, Kangawa K, Eto T: Production of adrenomedullin in human vascular endothelial cells. Life Sci 60: , Ishiyama Y, Kitamura K, Kato J, Sakata J, Kangawa K, Eto T: Changes in cardiac adrenomedullin concentration in renovascular hypertensive rats. Hypertens Res 20: , Kannan H, Iki K, Ishizuka Y, Kato K, Shimokawa A, Saita M, Kunitake T, Hanamori T: Effects of systemic interleukin-1β administration on daily drinking and renal excretory function in conscious rats. Physiol Behav 61: , Khan AI, Kato J, Kitamura K, Kangawa K, Eto T: Hypotensive effect of chronically infused adrenomedullin in conscious Wistar-Kyoto and spontaneously hypertensive rats. Clin Exp Pharmcol Physiol 24: , Khan AI, Kato J, Ishiyama Y, Kitamura K, Kangawa K, Eto T: Effect of chronically infused adrenomedullin in two-kidney, one-clip hypertensive rats. Eur J Pharmacol 333: , Kinoshita H, Nakazato M, Yamaguchi H, Matsukura S, Fujimoto S, Eto T: Increased plasma guanylin levels in patients with impaired renal function. Clin Nephrol 47: 28-32, Kinoshita H, Fujimoto S, Nakazato M, Yokota N, Date Y, Yamaguchi H, Hisanaga S, Eto T: Urine and plasma levels of uroguanylin and its molecular forms in renal diseases. Kidney Int 52: , Kuwasako K, Kitamura K, Ishiyama Y, Washimine H, Kato J, Kangawa K, Eto T: Purification and characterization of PAMP-12 (PAMP [9-20]) in porcine adrenal medulla as a major endogenous biologically active peptide. FEBS Lett 414: , Kuwasako K, Kida O, Kitamura K, Kato J, Eto T: Plasma adrenomedullin in cerebrovascular disease. Int Angiol 16: ,
4 16. Nagata N, Kitamura K, Kato J, Naruo H, Eto T, Takasaki M: The effect of hypothermic cardiopulmonary bypass on plasma adrenomedullin in adult cardiac surgical patients. Anesth Analg 84: , Nishio K, Akai Y, Murao Y, Doi N, Ueda S, Tabuse H, Miyamoto S, Dohi K, Minamino N, Shoji H, Kitamura K, Kangawa K, Matsuo H: Increased plasma concentrations of adrenomedullin correlate with relaxation of vascular tone in patients with septic shock. Crit Care Med 25: , Ogawa T, Bruneau BG, Yokota N, de Bold MLK, de Bold AJ: Tissue-specific regulation of renal and cardiac atrial natriuretic factor gene expression in deoxycorticosterone acetate-salt rats. Hypertension 30: , Sato Y, Fujimoto S, Hamai K, Eto T: Metalloproteinase activity is present in rat urine and derived from the renal cortex. Nephrology 3: , Yoshibayashi M, Kamiya T, Kitamura K, Saito Y, Kangawa K, Nishikimi T, Matsuoka H, Eto T, Matsuo H: Plasma levels of adrenomedullin in primary and secondary pulmonary hypertension in patients <20 years of age. Am J Cardiol 79: , ( ) 74: , I. (AM) (SHR) Wistar-Kyoto (WKY) Ther Res 18: , PAMP. 74: , CK 4
5 71: , : , : , : , Etoh T, Matsuda J, Hanada Y, Takenaga M, Koiwaya Y, Eto T: Recurrent syncope induced by left ventricular outflow tract obstruction: Demonstration in a patient with hypertrophic obstructive cardiomyopathy. J Cardiol 30: , Clinician 44 : , : , : , : , (bleb) CAPD 30: ,
6 7. ganciclovir. 30: , Kitamura K, Eto T: Adrenomedullin- physiological regulator of the cardiovascular system or biochemical curiosity? Curr Opin Nephrol Hypertens 6: 80-87, : 88-92, : , : , : 37-40, (AM) 182: , : , : , PAMP 55:81-88, : , : ,
7 12. No.16 : , No.17 : , No.16 : , : , Henry R. Black HOT Study. Medical Tribune 30 (52): 27-30, No. 569: 26-27, : 5, ( ) 229, : 7-8, Medical Tribune 30 (51): 20-21, : , PAMP Medical Academy News 657: 9,
8 33: , Ca vs ACE 15: , Aoki T, Ruffin MT, Vaerten MA, Burney KD, Normolle DP, Krishnan K, Boland CR, Brenner DE: Low dose aspirin modulation of premalignant biomarkers in rectal epithelium of high-risk subjects for colorectal cancer. The 88th Annual Meeting of the American Association for Cancer Research, (San Diego, USA) 2. Ishihara T, Katoh F, Kato J, Fujimoto S, Eto T: Erythropoietin induces adrenomedullin release from human vascular endothelial cells. The 14th International Congress of Nephrology, (Sydney, Australia) 3. Kinoshita H, Fujimoto S, Yokota N, Nakazato M, Eto T: Uroguanylin and its receptor guanylate cyclase (GC-C) in the kidney. The 14th International Congress of Nephrology, (Sydney, Australia) 4. Sato Y, Fujimoto S, Hamai K, Eto T: Serial alterations of glomerular matrix-degrading metalloproteinase activity in antithymocyte- induced glomerulonephritis (Thy.1 GN) in rats. The 14th International Congress of Nephrology, (Sydney, Australia) 5. Fukudome K, Yokota N, Fujimoto S, Hisanaga S, Eto T: Sustained increase of lipoprotein(a) [Lp(a)] in early and late diabetic nephropathy. The 14th International Congress of Nephrology, (Sydney, Australia) 6. Yokota N, Fujimoto S, Fukudome K, Hisanaga S, Eto T: Time course alterations of lipoprotein(a) [Lp(a)] in patients with chronic renal failure (CRF) on hemodialysis (HD). The 14th International Congress of Nephrology, (Sydney, Australia) 8
9 7. Eto T: Adrenomedullin and PAMP in cardiovascular diseases. NCI Adrenomedullin Symposium, (Washington DC, USA) 8. Kitamura K: Structure and function of adrenomedullin and PAMP. NCI Adrenomedullin Symposium, (Washington DC, USA) 9. Tsuruda T, Kato J, Kitamura K, Imamura T, Koiwaya Y, Eto T: Adrenomedullin: A possible autocrine or paracrine inhibitor of hypertrophy of rat cardiac myocytes. The Council for High Blood Pressure Research, 51st Annual Fall Conference and Scientific Sessions, (Washington DC, USA) 10. Kunitake T, Jin QH, Nose K, Shimokawa A, Ishizuka Y, Kato K, Saita M, Hamamori T, Kannan H: Comparison of cardiac-related activity between the single unit in the hypothalamic paraventricular nucleus region and renal sympathetic nerve activity in conscious rats. The 1st International Society for Autonomic Neuroscience, (Cairns, Australia) 11. Saita M, Shimokawa A, Kunitake T, Kato K, Hamamori T, Kitamura K, Eto T, Kannan H: Central effects of adrenomedullin on renal sympathetic nerve activity in conscious rats. The 1st International Society for Autonomic Neuroscience, (Cairns, Australia) 12. Shimokawa A, Jin QH, Ishizuka Y, Saita M, Kunitake T, Kannan H: Effects of intravenous anesthetics on central and peripheral catecholaminergic systems in conscious rats. The 1st International Society for Autonomic Neuroscience, (Cairns, Australia) 13. Kinoshita H, Fujimoto S, Yokota N, Date Y, Nakazato M, Eto T: Uroguanylin acts as a natriuretic factor via guanylate cyclase C in the kidney. The 30th Annual Meeting of American Society of Nephrology, (San Antonio, USA) 9
10 14. Fukudome K, Fujimoto S, Satoh Y, Hisanaga S, Eto T: Peritonitis increases matrix metalloproteinases (MMP)-9, but hyperosmolality decreases tissue inhibitor of MP (TIMP) in peritoneal dialysates in CAPD patients. The 30th Annual Meeting of American Society of Nephrology, (San Antonio, USA) 15. Yokota N, Fujimoto S, Fukudome K, Hisanaga S, Eto T: Urinary interleukin-6 (IL-6) as a useful therapeutic marker of lupus nephritis. The 30th Annual Meeting of American Society of Nephrology, (San Antonio, USA) 16. Kuwasako K, Kitamura K, Ishiyama Y, Kato J, Kangawa K, Eto T: Purification and characterization of PAMP-12 (PAMP [9-20]) in porcine adrenal medulla as the major endogenous biologically active peptide. The 70th Scientific Sessions of American Heart Associations, (Orland, USA) 17. Hirayama N, Kitamura K, Matsuda J, Imamura T, Koiwaya Y, Eto T: Mature form of circulating adrenomedullin: An evaluation in patients with congestive heart failure and its pathophysiological roles. The 70th Scientific Sessions of American Heart Associations, (Orland, USA) MyD 10
11 SD (AM) pro-adrenomedullin N-terminal 20 peptide (EHT) (MHT) I Two-kidney, one-clip (2KIC) (AM) (SHRSP/Izm) (AM) T-Helper 11
12 Na Uroguanylin proadrenomedullin N-terminal 20 peptide (PAMP) (FGS) (AM) PAMP ( ) 12
13 HD Vit D (OH) 2D3 low PTH CAPD matrix metalloproteinase (MMP) tissue-inhibitor of MP (TIMP) N
14 Tc-tetrofosmin PAMP-12 (PAMP [9-20]) IBD (SHRSP/Izm) (AM) (AC) (AM) (ANP) McDermott PJ Adrenomedullin 14
15 LDL (LDL-A) LP(a)
16 Crohn Thymoma stent Paget ARDS Still (RP ) (CAG)
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19 32. PAMP Double ileocecal valve LDH
20 15-deoxyspergualin (DSG) (MCTD) LDL-apheresis Thy IgA β 123 I-MIBG
21 CT T ASO atheroma embolism ASO atheroma embolism 14 MMC (EHT) (MHT) PAMP-12 (PAMP [9-20]) 1 Molecular Cardiovascular Conference
22 18. / Blood, Brain & Heart Council ' VSD TAE
23 6. MRC ( ) JLIT PAMP
24 PAMP
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