Department of Clinical Immunology

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5 1. Shiokawa S, Mortari F, Lima J, Nunez C, Bertrand FE, Kirkham PM, Zhu S, Dasanayake AP, Schroeder Jr HW Bothgenetic and somatic mechanisms limit the expression of long immunoglobulin HCDR3 intervals during ontogeny. J. Immunol. 162, Shiokawa S, Nishimura J, Uike N, Saburi Y, Suehiro T, Yamamoto K Clonal identities and multiple isotype transcripts in hematological diseases revealed bya a single-strand conformation polymorphism analysis of the immunoglobulin heavy chain messenger signals. Am J Hematol 62: Ohe K, Ikuyama S, Takayanagi R, Kohn LD, Nawata H Nicotinamide potentiates TSHR and MHC class II promoter activity in FRTL- 5 cells. Mol Cell Endocrinol 149: Hamaguchi K, Cong ND, Yanase T, Ikuyama S, Goto K, Takayanagi R, Nawata H, Kusuda Y, Fukagawa K, Sakata T Novel germline mutations of the MEN1 gene in Japanese patients with multiple endocrine neoplasia type 1. J Hum Genet 44: Nawata H, Yanase T, Oba K, Ichino I, Saito M, Goto K, Ikuyama S, Sakai H, Takayanagi R Human Ad4BP/SF-1 and its related nuclear receptor. J Steroid Biochem Mol Biol 69: Sugimura T, Motomura S, Sakai H, Nawata H Increased serum soluble IL-2 receptor levels following interferon therapy in patients with chronic hepatitis C. Hepato-Gastroenterol 46: Shiratsuchi M, Muta K, Umemura T, Nishimura J, Nawata H, Kozuru M Telomerase activity in myeloma cells is closely related to cell cycle status, but not to apoptotic signals induced by interferon-. Leukemia and Lymphoma 34: Fujikawa M, Okamura K, Sato K, Mizokami T, Shiratsuchi M, Fujishima M.

6 1999. Increased sensitivity to thyroid hormone replacement therapy followed by hyponatremia and eosinophilia in a patient with long-standing young-onset primary hypothyroidism. J Endocrinol Invest 22: Yoshida T, Kimura N, Sawada H, Suematsu E, Nagano M, Akiyoshi T, Motomura S, Kikuchi M, Nishimura J, Tamura K CD56+ CD7+ stem cell leukemia/lymphoma with D2-J 1 rearrangement. Int Medicine 38: Suehiro Y, Muta K, Umemura T, Abe Y, Nishimura J, Nawata H Macrophage inflammatory protein 1 arfa enhances in a different manner adhesion of hematopoietic progenitor cells from bone marrow, cord blood, and mobilized peripheral blood. Exp Hematol 27: Shiokawa S. Miyazaki Y, Nakamura M, Nkayama T, Ohshima K, Suehiro Y, Yamamoto K, Nishimrura J Expansion of identical B cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjogren s syndrome. Mod Rheumatol 10: Abe Y, Takatsuki H, Odada Y, Saito a, Kimura T, Nishimura J Mucosa-associated lymphoid tissue type lymphoma of the gallbladder associated with acute myeloid leukemia. Internal Med 38: Abe Y, Hirase N, Muta K, Okada Y, Kimura T, Umemura T, Nishimura J, Nawata H Adult onset of cyclic hematopoiesis in a patient with myelodysplastic syndrome. Int J Hematol 71: Hirase N, Yufu Y, Abe Y, Muta K, Shiokawa S, Nawata H, Nishimura J Primary macroglobulinemia with t(11;18)(q21;q21). Cancer Genet Cytogenet 117:

9 Mu YM, Oba K, Ashida K, Ito T, Ohe K, Yanase T, Ikuyama S, Takayanagi R, Nawata H. (1999, 6/12-6/15). Moleular cloning and tissue expression of human pituitary tumor transforming gene (hpttg).

10 81th Annual Meeting of The Endocrine Society, San Diego, CA, USA. Oba K, Yanase T, Ichino I, Goto K, Takayanagi R, Ikuyama S, Nawata H. (1999, 6/12-6/15). Transcriptional regulation of human FTZ-F1 gene that encodes adrenal 4- binding protein/steroidogenic factor 1 (Ad4BP/SF-1). 81th Annual Meeting of The Endocrine Society, San Diego, CA, USA. Ichino I, Yanase T, Oba K, Takayanagi R, Ikuyama S, Nawata H. (1999, 6/12-6/15). cdna cloning and expression of two isoforms of rat fushitarazu-factor 1 beta (FTZ-F1b). 81th Annual Meeting of The Endocrine Society, San Diego, CA, USA. Ikuyama S, Mu YM, Takayanagi R, Nishimura J, Nawata H. (1999, 6/15-6/17). Cell type-specific expression of estrogen receptor (ER) subtypes in human pituitary adenomas. 6 th The International Pituitary Congress, Long Beach, CA, USA. Muta K, Choi I, Abe Y, Suematsu E, Nishimura J, Nawata H. (1999, 10/24-10/28). Interferon gamma enhances survival of mature erythroid progenitor cells by reducing apoptosis. IX Congress of the International Society of Hematology, Asian-Pacific division. Bangkok, Thailand. Choi I, Muta K, Abe Y, Nishimura J, Nawata H. (1999/12/4-12/8). Interferon gamma protects mature erythroid progenitor cells from apoptosis by mechanism different from erythropoietin. 41th Annual Meeting of American Society of Hematology, New Orliens, USA. Suehiro Y, Shiokawa S, Uike N, Muta K, Nishimura J. (2000, 3/16-3/18). Analysis of immunoglobulin and mrna transcripts in Waldenstrom s mcroglobulinema. Asian Hematology Session in th 62nd Meeting of the Japanese society of Hemalology, Fukuoka, Japan.

研究成果報告書

研究成果報告書系レニン 1. Ito D, Ito O, Mori N, Suda C, Hao K, Cao P, Muroya Y, Takashima K, Shimokawa H, Kohzuki M. Exercise training upregulates nitric oxide synthases in the kidney of rats with chronic heart failure.