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WHO

20 SARS (World Health Organization WHO) Strategic and technical meeting on intensified control of neglected tropical diseases: A renewed effort to combat entrenched communicable diseases of the poor A report of an international workshop 2006 2007 HIV/AIDS 1 Buruli ulcer Neglected Tropical Diseases Neglected Tropical Diseases, Hidden successes, Emerging opportunities World Health Organization 2006 2015 Millennium Development Goals 1 2003 5 150 5 2 300-1 -

2 2 2 C. = = 2005 p29-2 -

1970 3 4 5 24 6 3 Mahbub ul Haq, The Poverty Curtain: Choices for the Third World (New York: Columbia University Press, 1976) Albert Fishlow at. el. Rich and Poor Nations in the World Economy (New York: McGraw-Hill Book, 1978) 4 Trickle Down Theory 5 PHP 2001 pp.71-73 150-151 2001 pp.21-22 6 2006 pp.1-2 NGO NGO NGO 2004 p45-3 -

7 20 8 50 9 WHO 2001 pp.15-17 7 1 8 2006 2006 1 27 13 http://webnews.asahi.co.jp/you/special/2007/t20070919.html 2007 12 16 9 2006 1 27 13 2006 4 21 25-4 -

WHO HIV / HIV / 1960 1970 1983 Centers for Disease Control and Prevention WHO HIV / 1 WHO HIV / 2003 Neglected Tropical Diseases 10 Neglected Tropical Diseases Neglected Tropical Diseases, Hidden successes, Emerging opportunities 11 14 Buruli ulcer Leishmaniasis Chagas disease Leprosy Cholera/Epidemic diarrhoeal diseases Lymphatic filariasis Dengue/dengue haemorrhagic fever 10 World Health Organization Strategic and technical meeting on intensified control of neglected tropical diseases: A renewed effort to combat entrenched communicable diseases of the poor A report of an international workshop 2006 pp. - 11 World Health Organization Neglected Tropical Diseases, Hidden successes, Emerging opportunities 2006 p - 5 -

Onchocerciasis Dracunculiasis (guinea-worm disease) Schistosomiasis Endemic Treponematoses (yaws, pinta, endemic syphilis ) Soil-transmitted helminthiasis Trachoma Human African trypanosomiasis 14 12 WHO Neglected Tropical Diseases, Hidden successes, Emerging opportunities 13 10 50 5 1 70 5 1 ( 12 ) 1 1 14 47 1 1 1 12 Kingsley Asiedu and Samuel Etuaful, Socioeconomic Implications of Buruli Ulcer in Ghana: A Three-Year Review, The American Society of Tropical Medicine and Hygiene Vol. 59(6) (1998): 1015-1022 13 World Health Organization Neglected Tropical Diseases, Hidden successes, Emerging opportunities 2006 p p3 14 Millennium Development Goals MDGs 2005 p9-6 -

1 2 diseases 2 David H. Molyneux, Peter J. Hotez, Alan Fenwick Rapid-Impact Interventions:How a Policy of Integrated Control for Africa s Neglected Tropical Diseases Could Benefit the Poor Volume2 Isse11 2005 p1065(e336) 1 1 1 100 1990 1999 1990 1999 47.7 46.7 242 300 27.6 14.2 452 260 18.5 7.9 92 46 44.0 36.9 495 490 16.8 15.1 74 77 1.6 3.6 7 17 2.4 2.3 6 7 29.0 22.7 1276 1151 28.1 24.5 916 936 United Nations Development Programme Human Development Report 2002 Oxford University Press, 2002 p18-7 -

2000 15 1 3000 2000 16 17 HIV/ 15 Tzaraath Repra Mycobacterium leprae 2001 p117 16 2006 p44 17 pp.63-64 = 1988 pp.166-167 - 8 -

2000 IMS Health 3370 39 27 16 7 11 11 1.3 18 1995 95,417 182 19 1975 1999 1,393 1 20 2 1 0.40 1 Neglected tropical disease 2 Onchocerciasis 0.10 0.20 Lymphatic filariasis 0.03 1.50 Soil-transmitted helminthiasis 0.02 Trachoma 0.30 Schistosomiasis 0.20 0.30 Vitamin A deficiency 0.02 Total estimated range of chemotherapy package of annual treatments for all above diseases Unit cost per treatment (US$) Circa $0.40 World Health Organization Neglected Tropical Disease, Hidden successes, Emerging opportunities 2006 p10 18 NGO WTO TRIPS TRIPS No.51 2003 p102 Tileman-Dothias von Schoen-Angerer The Informed Prescriber 15 11 2000 pp.117-118 19 p102 20 World Health Organization Neglected Tropical Diseases, Hidden successes, Emerging opportunities 2006 p3-9 -

10 NGO WHO (Millennium Development Goals) 21 HIV/AIDS HIV/AIDS (Global health security) Neglected Tropical Diseases HIV/AIDS 21 1990 2000 9 8 2015 WHO 8 7-10 -

WHO 22 14 3 3 WHO http://www.who.int/en/ 23 22 World Health Organization Strategic and technical meeting on intensified control of neglected tropical diseases: A renewed effort to combat entrenched communicable diseases of the poor A report of an international workshop 2006 p 23 CDC(Centers for Disease Control and Prevention) Progress Toward Global Eradication of Dracunculiasis, January 2004-July 2005 MMWR(Morbidity and Mortality Weekly Report) Volume54 Issie42 2004 pp.1075-1077 - 11 -

WHO WHO FACT SHEET BURULI ULCER DISEASE Mycobacterium ulcerans infecation Buruli ulcer, Mycobacterium ulcerans infection Buruli ulcer- Diagnosis of Mycobacterium ulcerans disease Buruli ulcer- Management of Mycobacterium ulcerans disease 24 1897 Kampala Mengo 1948 MacCallum 1960 Buruli Nakasongola Buruli Ulcer 1980 2 32 1978 2006 24,000 1989 2006 7,000 1993 11,000 24 World Health Organization FACT SHEET BURULI ULCER DISEASE(Mycobacterium ulcerans infecation) 2007 World Health Organization/Global Buruli Ulcer Initiative Buruli ulcer, Mycobacterium ulcerans infection 2000 World Health Organization Buruli ulcer - Diagnosis of Mycobacterium ulcerans disease 2001 World Health Organization Buruli ulcer - Management of Mycobacterium ulcerans disease 2001-12 -

2 World Health Organization http://www.who.int/buruli/en/ 2007 4 22 Mycobacterium Ulcerans 3 1 3 Papule 1cm 2 4 Nodule Plaque 1 2cm Papule 3 5 Oedematous form - 13 -

3 Papule 4 Nodule Plaque 5 Oedematous form World Health Organization http://www.who.int/buruli/photos/no nulcerative/en/index.html 2008 1 16 Dr J. Hayman, Australia 2006 3 11 World Health Organization http://www.who.int/buruli/photos/no nulcerative/en/index.html 2008 1 16 Dr A. Paintsil, Ghana 2008 1 2001 2003 76.20 16 428 89 8 3 7 15 25 25 http://www.nippon-foundation.or.jp/inter/topics_dtl/2001471/20014711.html 2007 10 23-14 -

1998 Neglected Tropical Diseases 2000 Millennium Development Goals WHO 14 Buruli ulcer 32-15 -

- 16 -

2006 NGO NGO NGO 2004 2001 2001 PHP 2001 2006 2001 C. = = 2005 = 1988 NGO WTO TRIPS TRIPS No.51 2003 Tileman-Dothias von Schoen-Angerer The Informed Prescriber 15 11 2000 Millennium Development Goals MDGs 2005 2006 1 27 13 2006 4 21 25 WHO World Health Organization/Global Buruli Ulcer Initiative Buruli ulcer, Mycobacteri- - 17 -

um ulcerans infection 2000 World Health Organization Buruli ulcer - Diagnosis of Mycobacterium ulcerans disease 2001 World Health Organization Buruli ulcer - Management of Mycobacterium ulcerans disease 2001 World Health Organization Strategic and technical meeting on intensified control of neglected tropical diseases: A renewed effort to combat entrenched communicable diseases of the poor A report of an international workshop 2006 World Health Organization Neglected Tropical Diseases, Hidden successes, Emerging opportunities 2006 World Health Organization FACT SHEET BURULI ULCER DISEASE(Mycobacterium ulcerans infecation) 2007 CDC(Centers for Disease Control and Prevention) Progress Toward Global Eradication of Dracunculiasis, January 2004-July 2005 MMWR(Morbidity and Mortality Weekly Report) Volume54 Issie42 2004 David H.Molyneux, Peter J.Hotez, Alan Fenwick Rapid-Impact Interventions :How a Policy of Integrated Control for Africa s Neglected Tropical Diseases Could Benefit the Poor Volume2 Issie11 2005 Kingsley Asiedu and Samuel Etuafl, Socioeconomic Implications of Buruli Ulcer in Ghana: A Three-Year Review, American Journal of Medicine and Hygiene, 56 (6) 1998 United Nations Development Programme Human Development Report 2002 Oxford University Press, 2002 Web http://webnews.asahi.co.jp/you/special/2007/t20070919.html http://www.nippon-foundation.or.jp/inter/topics_dtl/2001471/20014711.html World Health Organization http://www.who.int/en/ http://www.who.int/buruli/en/ http://www.who.int/buruli/yamoussoukro_declaration/en/index.html http://www.who.int/buruli/photos/nonulcerative/en/index.html - 18 -