tmrna tmrna RNA mrna turnover RNase class I peptide release factor RF ribosome rescue trna mrna transfer-messenger RNA tmrna RNA tmrna SmpB trna transtranslation C tmrna mrna ATP tmrna tmrna tmrna-independent ribosome rescue systems in bacteria and mitochondria Nobukazu Nameki Division of Molecular Science, Faculty of Science and Technology, Gunma University, Tenjincho, Kiryu-shi, Gunma, Japan tmrna tmrna SmpB tmrna ssra mrna tmrna tmrna YaeJ ArfA YaeJ RF trna PTH GGQ Gly-Gly-Gln YaeJ tmrna YaeJ ICT DNA mtdna tmrna SmpB ICT GGQ Corf tmrna GGQ pp.
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GGQ A GGQ GGQ GGQ αi α-helix BGGQ α β α-helix β-strand -helix C CorfPDB code RSM ICTJ mrna YaeJ mrna RNase mrna A-site cleavagetmrna SmpB YaeJ Steitz YaeJ Thermus thermophilus
YaeJ ICT Corf A SDS YaeJ PTH B RNAi ICT Corf si-nt non-targeting duplex sirnas C ICT Corf MitoTracker Red CMXRos MitoTracker Green FM Flow cytometry RF P trna trna YaeJ C α-helix mrna entry channels mrna α-helix flexible linker α-helix S SmpB YaeJ C tmrna SmpB A C α-helix mrna entry channel YaeJ SmpB YaeJ S RNA G syn anti mrna A YaeJ mrna entry channel mrna YaeJ C YaeJ T. thermophilus ICT ICTHT-D immature colon carcinoma cell transcript ICT Chrzanowska-Lightowlers ICT
ICT sirna ICT mtdna S ICT PTH nonstop mrna ICT ICT mtdna Corf tmrna SmpB ICT ICT GGQ Corf corf nonsense Corf corf nonsense Shoubridge ICT ICT c COX Corf ICT ICT S nonstop mrna PTH PTH PTH ICT Corf Flow cytometry ICTCorf RNAi ICT Corf B Corf ICT C ICT Corf ICT Corf GGQ YaeJ ArfA yhdl ArfA ArfA tmrna ArfA mrna C RNase III nonstop mrna tmrna SmpB ArfA C tmrna SmpB tmrna ArfA ArfA ArfA tmrna YaeJ ArfA GGQ PTH
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