I. はじめに ) Body Mass Index 2012 BMI stage 1 Isometric Knee 2) Extension Force; IKEF 6 6-Minute 3) Walk Distance; 6MWD Quality

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1 原著 Characteristics of Fatigue of Gastrointestinal Cancer Patients in the Perioperative Period 1,2) 1) 1,3) 2) EISUKE KOGURE, RPT 1,2), TSUYOSHI HARA, RPT, PhD 1), TAKAYA ISHII, RPT 1,3), MASAHARU MAEDA, MD 2) 1) Division of Rehabilitation, International University of Health and Welfare, Mita Hospital: Mita 1-4-3, Minato-ku, Tokyo , Japan. TEL eisuke0590@yahoo.co.jp 2) Department of Rehabilitation, International University of Health and Welfare Graduate School 3) Department of Physical Therapy, International University of Health and Welfare Graduate School Rigakuryoho Kagaku 30(6): , Submitted May 29, Accepted Jul. 27, ABSTRACT: [Purpose] This study investigated the characteristics of fatigue of gastrointestinal cancer patients in the perioperative period. [Subjects and Methods] Thirty-three gastrointestinal cancer patients were assessed using the cancer fatigue scale (CFS) and their characteristics of fatigue were investigated using factor analysis of CFS subscales. [Results] Three factors were identified and their loadings were respectively 24.5, 17.9, and 17.3%. They were different from the original CFS factors of physical, mental, and cognitive fatigue, and were interpreted as physical durability, mental, and initial action fatigue. [Conclusion] In gastrointestinal cancer patients, physical durability and initial action fatigue are commingled, and there is a possibility that unique characteristics of fatigue, including various factors, exist. Key words: gastrointestinal cancer patients, fatigue, perioperative period 要旨 : 33 Cancer Fatigue Scale CFS CFS 3 キーワード : 1) : TEL ) 3)

2 I. はじめに ) Body Mass Index 2012 BMI stage 1 Isometric Knee 2) Extension Force; IKEF 6 6-Minute 3) Walk Distance; 6MWD Quality of Life QOL IKEF HUR QOL 1 kgf Nm/ kg 4) 6MWD 50 m 30 5,6) ,8) SDM-1 m QOL Cancer Fatigue Scale 9,10) CFS 15) CFS 11) 3 12) 13) CFS ) 16) QOL Hospitality Anxiety and Depression scale HAD HAD QOL 17,18) Alb CRP II. 対象と方法 2 1 Wilcoxon CFS S 8

3 869 表 1 CFS IBM SPSS statistics ver 表 min ml stage Mean SD. III. 結 ml 31 2 果表 3 6MWD IKEF BMI 6MWD HAD Alb CRP IKEF CFS CFS HAD CFS kg * BMI kg/m * IKEF N/m/kg MWD m * CFS * HAD * Alb g/dl * CRP mg/dl * Mean SD *p<0.05

4 表表 * * * * * CFS * IV. 考察 * *:, : BMI 19) 20) 1 CRP Alb 6MWD IKEF 6MWD 21)

5 871 HAD 22) HAD 22) 22) 3 CFS 2 CFS CFS 1 2 CFS 3 CFS /3 23) ) ) CFS ) CFS 17.1 CFS 16,24 26) CFS stage 27) 6MWD 引用文献 1) http// seisakunitsuite/bunya/kenkou_iryou/kenkou/gan/index.html ) (12): ) 2010 pp ) NCCN http// ) Degner LF, Sloan J: Symptom distress in newly diagnosed ambulatory cancer patients and as a predictor of survival in lung cancer. J Pain Symptom Manage, 1995, 10(6): ) Bower JE, Ganz PA, Desmond KA, et al.: Fatigue in breast cancer survivors: occurrence, correlates, and impact on quality of life. J Clin Oncol, 2000, 18(4): ) Stone P, Hardy J, Broadley K, et al.: Fatigue in advanced cancer: A prospective controlled cross-sectional study. Br Cancer, 1999, 79(9 10): ) Kutner JS, Kassner CT, Nowels DE: Symptom burden at the end of life: hospice providers perceptions. J Pain Symptom Manage, 2001, 21(6): ) Courneya KS, Mackey JR, Bell GJ, et al.: Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: cardiopulmonary and quality of life outcomes. J Clin Oncol, 2003, 21(9): ) Cramp F, Daniel J: Exercise for the management of cancerrelated fatigue in adults. Cochrane databace Syst Rev, 2008, 16(2): ) Richardson A: Fatigue in cancer patients: a review of the literature. Eur J Cancer, 1995, 4(1): ) Escalante CP, Grover T, Johnson BA, et al.: A fatigue clinic in a comprehensive cancer center: design and experiences. Cancer, 2001, 92(6):

6 ) Winningham ML, Nail LM, Burke MB, et al.: Fatigue and the cancer experience: the state of the knowledge. Oncol Nurs Forum, 1994, 21(1): ) Matsuda T, Marugame T, Kamo K, et al.: The Japan cancer surveillance research group. Cancer incidence and incidencerates in Japan in 2005: based on data from 12 population based cancer registries in the monitoring of cancer incidence in Japan (MCIJ) project. J Clin Oncol, 2011, 41(1): ) Okuyama T, Akechi T, Kugaya A, et al.: Development and validation of the cancer fatigue scale: a brief, three dimensional, self-rating scale for assessment of fatigue in cancer patients. J Pain Symptom Manage, 2000, 19(1): ) Okuyama T, Akechi T, Kugaya A, et al.: Fatigue in ambulatory patients with advanced lung cancer: prevalence, correlated factors, and screening. J Pain Symptom Manage, 2001, 22(1): ) hospital anxiety and depression scale HAD (12): ) hospital anxiety and depression scale (5): ) Fairey AS, Courneya KS, Field CJ, et al.: Physical exercise and immune system function in cancer survivers. Cancer, 2002, 94(2): ) Lin E, Lowry SF, Calvano SE, et al.: Schwartz s principles ofsurgery. McGraw-Hill, New York, 2005 pp ) Quality of Life (3): ) (1): ) QOL (5): ) QOL (4): ) : ) (1): ) (6):

8 The Bulletin of Meiji University of Integrative Medicine API II 61 ASO X 11 7 X-4 6 X m 5 X-2 4 X 3 9 X 11 7 API 0.84 ASO X 1 1 MR-angio

8 The Bulletin of Meiji University of Integrative Medicine API II 61 ASO X 11 7 X-4 6 X m 5 X-2 4 X 3 9 X 11 7 API 0.84 ASO X 1 1 MR-angio 7-14 2010 1 1 1 2 1 1 1 2 Fontaine II ASO61 3 API ASO ASO ASO API API KKKKKKKKKK ASO Fontaine II API Received April 14, 2009; Accepted July 16, 2009 I arteriosclerosis obliterans: ASO ASO 50 70 1,2 Fontaine