3 1 3 * ** Key Words : non valvular atrial fibrillation, novel oral anticoagulant, warfarin, CHADS2 score, HAS BLED score NVAF 9

Size: px
Start display at page:

Download "3 1 3 * ** Key Words : non valvular atrial fibrillation, novel oral anticoagulant, warfarin, CHADS2 score, HAS BLED score NVAF 9"

Transcription

1 3 3 * ** Key Words : non valvular atrial fibrillation, novel oral anticoagulant, warfarin, CHADS score, HAS BLED score NVAF 9 NVAF I NVAF. CHADS CHADS 5 Table warfarin Table 0 warfarin CHADS warfarin warfarin Fig Fig.. CHADS VASc CHADS VASc Table 4 CHADS CHADS warfarin warfarin Table 3 3 CHADS 3 CHADS Prevention of Stroke in Patients with Non valvular Atrial Fibrillation. Masahiro YASAKA : Department of Cerebrovascular Medicine, National Hospital Organization Kyushu Medical Center Vol. 3 No

2 Table CHADS and CHADS VASc scores CHADSCHADS VASc Congestive heart failure Congestive heart failure/left ventricular dysfunction / Hypertension Hypertension Age 75 yrs 75 Age 75 yrs 75 Diabetes mellitus Diabetes mellitus Stroke/transient ischemic attack / Stroke/transient ischemic attack/te // Vascular disease prior myocardial infarction, peripheral artery disease or aortic plaque Age yrs Sex category i.e. female gender Table CHADS and CHADS VASc scores CHADSCHADS VASc CHADS CHADS VASc Gage BF : JAMA 00 ; 85 : Lip GY : Chest 00 ; 37 : warfarin CHADS CHADS VAScESC European Society of Cardi ology II HAS BLED Pisters HAS BLED Table 300 ESC 6 8 HAS BLEDHypertension Abnormal renal and liver function Stroke Bleeding Labile INRs Elderly Drugs and alcohol Table 3 7 HAS BLED Abnormal renal and liver function Drugs and alcohol NSAIDs Vol. 3 No

3 心房細動に伴う脳梗塞の予防 Fig. Guideline for pharmacotherapy of atrial fibrillation from the Japanese Circulation Society. quoted from reference 3 * 血管疾患とは心筋梗塞の既往 大動脈プラーク および末梢動脈疾患などをさす * 人工弁とは機械弁 生体弁をともに含む *3 04 年 7 月の時点では保険適応未承認 もしくはアルコール依存症で 点ずつのため 全部で 9 点満点 Table 3 HAS-BLED score HAS-BLED スコア である 頭文字 臨床像 ポイント クは増加する 大出血リスクは 0 点で低リスク 年間大出血 H 高血圧 発症リスク 点で中等度リスク 4 3 点以 A 腎 肝機能障害 各 点 S 脳卒中 B 出血 3 L 不安定な国際標準比 INR 4 導が大切である 抗血栓療法の併用をできるだけ避けること E 高齢者 65 歳より高齢 も求められる HAS-BLED スコアが高い場合に 抗血栓療 D 薬剤 アルコール 各 点 5 HAS-BLED スコア 0 9 点 が上昇すると大出血リス 上で高リスク 4 6 である HAS-BLED スコアが 3 点以上で高い場合は 大出血のリ スク管理が極めて重要である 頭蓋内出血のリスクである血 圧や血糖管理 過度のアルコール摂取を避けることや禁煙指 法を弱く行うべきとの主張があるが この対応は慎重であら 9 ねばならない まず 抗血栓療法を弱く行って十分な効果が 収縮期血圧 60mmHg 腎機能障害 慢性透析や腎移植 血清クレアチニン 00μmol/ l.6mg/dl 以上 肝機能異常 慢性肝障害 肝硬変など または検査値異常 ビリ ルビン値 正常上限 倍 AST/ALT/ALP 正常上限 3 倍 3 過去の出血歴かつ / または出血傾向 出血素因 貧血など 4 不安定な / 高値 INR または TTR 治療時間域 60 未満 5 抗血小板薬や NSAIDs 併用 またはアルコール依存症 確保できるというエビデンスが乏しいこと HAS-BLED の 項目の多くは CHADS スコアや CADS-Vasc スコアと重複 しており HAS-BLED スコアが高い症例は CHADS スコア や CADS-VASc スコアも高く 脳梗塞や全身塞栓症のハイ リスク症例だからである したがって 抗血栓療法を弱めに 行うよりも まず 大出血や頭蓋内出血のリスク管理を徹底 神経治療 Vol. 3 No

4 Table 4 Features of each novel oral anticoagulant IIa Xa Xa Xa Tmax CYP3A4/J CYP3A4 CYP3A Yes No No No / & / III Warfarin. novel oral anticoagulants NOAC warfarin heparin 3 NOAC warfarin 9 NOAC warfarin Fig. CHADS 3 warfarin CHDS dabigatran apixaban warfa rin dabigatran apixaban warfarin dabigatran apixaban CHADS dabigatran apixaban 9, 4, 5 NOAC Rivaroxaban edoxaban III CHADS CHADS. Warfarin Warfarin NOAC warfarin NOAC PT INR IV NOAC dabigatran rivaroxaban apixaban Table 4 6. Dabigatran DabigatranCHADS APTT 9, 5, 7, 8. Rivaroxaban Rivaroxaban Vol. 3 No

5 0, 8, 9 CHADS 3. Apixaban Apixaban CHADS APTT 4. Edoxaban Edoxaban 3 PT INR NOAC warfarin NOAC warfarin COI Gage BF, Waterman AD, Shannon W et al : Validation of clini cal classification schemes for predicting stroke. Resulte from the National Regisry of Atrial Fibrillation. JAMA 85 : , 00 Ogawa S, Hori M : Urgent statement on antithrombotic thera py of atrial fibrillation. Circ J 75 : 79 7, 0 3 Olesen JB, Lip GY, Hansen ML et al : Validation of risk stratifi cation schemes for predicting stroke and thromboembolism in patients with atrial fibrillation : nationwide cohort study. BMJ 34 : d4. doi: 0.36/bmj.d4., 0 4 Lip GY, Nieuwlaat R, Pisters R et al : Refining clinical risk stratification for predicting stroke and thrombo embolism in atrial fibrillation using a novel risk factor based approach : the euro heart survey on atrial fibrillation. Chest 37 : 63 7, 00 5 Toyoda K, Yasaka M, Iwade K et al ; Bleeding with Antithrom botic Therapy BAT Study Group : Dual antithrombotic ther apy increases severe bleeding events in patients with stroke and cardiovascular disease : a prospective, multicenter, obser vational study. Stroke 39 : , Pisters R, Lane DA, Nieuwlaat R et al : A novel user friendly score HAS BLED to assess year risk of major bleeding in patients with atrial fibrillation : the Euro Heart Survey. Chest 38 : , 00 7 European Heart Rhythm Association, European Association for Cardio Thoracic Surgery : Guidelines for the management of atrial fibrillation : The Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology ESC. Europ Heart J 3 : , 00 8 Lip GY, Frison L, Halperin JL et al : Comparative validation of a novel risk score for predicting bleeding risk in anticoagulat ed patients with atrial fibrillation. J Am Coll Cardiol 57 : 73 80, 0 9 Connolly SJ, Ezekowitz MD, Yusuf S et al ; RE LY Steering Committee and Investigators : Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 36 : 39 5, 009 and Erratum in : N Engl J Med 363 : 877, 00 0 Patel MR, Mahaffey KW, Garg J et al : ROCKET AF Investiga tors : Rivaroxaban versus warfarin in nonvalvular atrial fibril lation. N Engl J Med 365 : , 0 Granger CB, Alexander JH, McMurray JJ et al : ARISTOTLE Committees and Investigators. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 365 : 98 99, 0 Giugliano RP, Ruff CT, Braunwald E et al : Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med 369 : , htp:// circ.or.jp/guideline/ pdf/jcs 03_inoue_h.pdf Hart RG, Diener HC, Yang S et al : Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfa rin or dabigatran : The RE LY trial. Stroke 43 : 5 57, 0 5 Oldgren J, Alings M, Darius H et al : Risks for stroke, bleeding, and death in patients with atrial fibrillation receiving dabiga tran or warfarin in relation to the CHADS score : a subgroup analysis of the RE LY trial. Ann Intern Med 55 : , 0 6 Ogawa S, Koretsune Y, Yasaka M et al : Antithrombotic thera py in atrial fibrillation : evaluation and positioning of new oral anticoagulant agents. Circ J 75 : , 0 7 dabigatran 7 : 3 8, 0 8 Yasaka M : Current strategy for anticoagulation therapy for pa tients with non valvular atrial fibrillation. J Arrhythmia 8 : 34 33, 0 9 Hori M, Matsumoto M, Tanahashi N et al : Rivaroxaban vs. warfarin in Japanese patients with atrial fibrillation. Circ J 76 : 04, 0 Vol. 3 No

6 Prevention of Stroke in Patients with Non valvular Atrial Fibrillation Masahiro YASAKA Department of Cerebrovascular Medicine, National Hospital Organization Kyushu Medical Center Non valvular atrial fibrillation NVAF is the most common cardiac source of emboli in cardioembolic stroke which occupies 0 to 35% of acute brain infarction in Japan. In order to prevent the cardioembolic stroke, nock out type brain infarction, in NVAF patients, warfarin treat ment has been spread since guideline of the anticoagula tion for prevention of stroke in NVAF was issued. However, it has many limitations that make its use difficult. About half of patients with NVAF, who were indicated to warfarin treatment, are treated with warfarin. Bleeding complica tions including devastating intracranial hemorrhage has become a big concern during warfarin treatment. Novel oral anticoagulants NOAC are superior to warfarin, be cause they are easy to use, their effect in preventing isch emic stroke is higher than or as high as warfarin, their inci dence of major hemorrhage is lower than or as low as warfarin, and their incidence of intracranial hemorrhage is much lower than warfarin. CHADS and CHADS Vasc scores are used for stratification of stroke and HAS BLED score are for major hemorrhage during warfarin treatment. In this review, current strategies of anticoagulation for pre vention of stroke in NVAF are discussed. Vol. 3 No

36:378 第 38 回日本脳卒中学会講演シンポジウム 原著 36: , 要旨 TIA 2 t-pa Key words: stroke registry, stroke subtype, onset-visi

36:378 第 38 回日本脳卒中学会講演シンポジウム 原著 36: , 要旨 TIA 2 t-pa Key words: stroke registry, stroke subtype, onset-visi 36:378 第 38 回日本脳卒中学会講演シンポジウム 原著 36: 378 384, 2014 1 2 要旨 1999 2012 10 31 29 26 80 30 TIA 2 t-pa Key words: stroke registry, stroke subtype, onset-visit time, chronological change はじめに 4 12 23 27 1 Japan

More information

老人性不整脈

老人性不整脈 資料 : QOL CHADS NOAC はじめに common disease 高齢者の不整脈の頻度, AF AVB RBBB LBBB Cardiovascular Health Study, 137 表 1 Outpatient Atarashi Cardiovascular Health Study Monolio No F M Ectopic beats Supraventricular.

More information

PowerPoint プレゼンテーション

PowerPoint プレゼンテーション Journal Club AF 患者における 消化管出血後の抗凝固療法の再開 聖マリアンナ医科大学西部病院後期研修医吉田稔指導医吉田徹 2016.04.05 本日の論文 背景 抗血栓療法を施行している心房細動の患者において 消化管出血は頻度の多い出血合併症であることが 知られている 消化管出血後に抗血栓療法を再開するべきかどうか 判断に迷うことが多いが そのデータは少ない 心房細動 (AF) の抗血栓療法に関して

More information

日経メディカルの和訳の図を見ても 以下の表を見ても CHA2DS2-VASc スコアが 2 点以上で 抗凝固療法が推奨され 1 点以上で抗凝固療法を考慮することになっている ( 参考文献 1 より引用 ) まあ 素直に CHA2DS2-VASc スコアに従ってもいいのだが 最も大事なのは脳梗塞リスク

日経メディカルの和訳の図を見ても 以下の表を見ても CHA2DS2-VASc スコアが 2 点以上で 抗凝固療法が推奨され 1 点以上で抗凝固療法を考慮することになっている ( 参考文献 1 より引用 ) まあ 素直に CHA2DS2-VASc スコアに従ってもいいのだが 最も大事なのは脳梗塞リスク CHA2DS2-VASc スコア / HAS-BLED スコア (101105) 欧州心臓学会 (ESC2010) で 新しい心房細動 (AF) ガイドラインが発表された CHADS2 スコアにやっと慣れつつあったところだが CHA2DS2-VASc スコアやら HAS-BLED スコアなんて言葉が並んでいて混乱 どうやら CHADS2 スコアが 0~1 点の場合でもリスクを評価して抗凝固療法に結びつけるという流れのようだ

More information

C/NC : committed/noncommitted

C/NC : committed/noncommitted C/NC : committed/noncommitted 110 time post-icd implant 1) The Cardiac Arrhythmia Suppression Trial (CAST) Investigators Preliminary report : Effect of encainaide and flecainide on mortality in a

More information

1) University Group Diabetes Program: A study of hypoglycemic agents on vascular complica- in patients with adult-onset tions diabetes. I. Design, methods and baseline results. Diabetes 19 (suppl. 2):

More information

天理よろづ相談所学術発表会 2015 天理医学紀要 2016;19(2):90-94 DOI: /tenrikiyo 血栓一次予防 - 循環器領域から - 近藤博和 天理よろづ相談所病院循環器内科 はじめに循環器疾患における主要な血栓一次予防として, 二つの病態があげら

天理よろづ相談所学術発表会 2015 天理医学紀要 2016;19(2):90-94 DOI: /tenrikiyo 血栓一次予防 - 循環器領域から - 近藤博和 天理よろづ相談所病院循環器内科 はじめに循環器疾患における主要な血栓一次予防として, 二つの病態があげら 天理よろづ相談所学術発表会 2015 天理医学紀要 2016;19(2):90-94 DOI: 10.12936/tenrikiyo.19-011 血栓一次予防 - 循環器領域から - 近藤博和 天理よろづ相談所病院循環器内科 はじめに循環器疾患における主要な血栓一次予防として, 二つの病態があげられる. 一つは虚血性心疾患の一次予防としての抗血小板薬の投与であり, もう一つは心房細動患者における主に脳血栓塞栓症予防としての抗血栓薬の投与である.

More information

審査報告書(案)

審査報告書(案) 19 83 7 18 628 1 19 8 3 7 18 6 28 30 MI 31 360 21700BZY00247000 5mm CEA 59 mm 2 50% 80 1. 2. 3 19 8 3 [ ] 7 [ ] [ ] [ ] [ ] 18 6 28 [ ] CEA 49mm 50 80 2 4 carotid endarterectomy CEA 1,2 CEA ECST 3 NASCET

More information

_心臓49-6_HS.indd

_心臓49-6_HS.indd フレイル高齢者に対する心臓病治療の問題点 ₆₅ ₂₃% ₁ ₁ ₁ 心臓 Vol. 49 No.6(2017) ₃ ₁ ₂ ₃₇ DOACs TIA ₈ CHADS ₂ ₉ CHA ₂ DS ₂ VASc ₁₀ ₁₁ CHA ₂ DS ₂ VASc ₁₂ AF ₁₃ AF CHA ₂ DS ₂ VASc HAS BLED ₁₄ HAS BLED K Ⅹa Warfarin Dabigatran Rivaroxaban

More information

21-07_後藤論文.smd

21-07_後藤論文.smd 2015; 21: 5866 Yoichi Goto: Current status and future perspective of cardiac rehabilitation in Japan. J Jpn Coron Assoc 2015; 21: 5866 I 1 1 3 1 2 3 QOL 2 Fig. 1 1 196070 AMI AMI 1980 AMI CABG comprehensive

More information

心電図34-2

心電図34-2 高齢者が増え続ける今, 脳梗塞にいかに立ち向かうか 実臨床での心房細動管理における抗凝固薬の役割と今後の展開 Role and Future Development of Novel Oral Anticoagulants for Managing Atrial Fibrillation in Clinical Practice 池田隆徳 東邦大学医学部内科学講座循環器内科学分野 杏林大学医学部第二内科教授を経て,2011

More information

「心房細動における抗血栓療法に関する緊急ステートメント《

「心房細動における抗血栓療法に関する緊急ステートメント《 心房細動における抗血栓療法に関する緊急ステートメント 心房細動治療( 薬物 ) ガイドライン (2008 年改訂版 ) が公表されたのは 2009 年 11 月で 2001 年版の部分改訂とは言え大きく内容が変更され 心房細動に対する最適な治療指針として広く日常診療の場で利用されてきた 中でも 抗血栓療法を心房細動例への最も重要な治療法と位置づけ 我が国の臨床試験成績も勘案して独自の指針を示した 抗血小板薬を適応から除外し

More information

E Societe de Pathologie Infectieuse de Langue Francaise (, 1991) E Spanish Thoracic Society (1992) E American Thoracic Society (ATS : 1993. ü ù2001 ) E British Thoracic Society (1993, ü è2001 ) E Canadian

More information

clinical question

clinical question 9.2. Antithrombotic Therapy Class I 1. After AVR with bileaflet mechanical or Medtronic Hall prostheses, in patients with no risk factors,* warfarin is indicated to achieve an INR of 2.0 to 3.0. If the

More information

特殊病態下感染症における抗菌薬治験の手引き作成委員会報告書(案)

特殊病態下感染症における抗菌薬治験の手引き作成委員会報告書(案) VOL.51 NO.6 JUNE 2003 JUNE 2003 9) Niederman MS et al: Guidelines for the management of adults with community-acquired pneumonia. Diagnosis, assessment of severity, antimicrobial therapy and prevention.

More information

37:42 脳 卒 中 37 巻 1 号 (2015:1) Fig. 1 1 A: CT: B: MRI:T2 star weighted MR angiography microbleeds 4/5 14 2:76 : : 15 mg :20 : 174 cm 80.2 kg 209/96 mmh

37:42 脳 卒 中 37 巻 1 号 (2015:1) Fig. 1 1 A: CT: B: MRI:T2 star weighted MR angiography microbleeds 4/5 14 2:76 : : 15 mg :20 : 174 cm 80.2 kg 209/96 mmh 37:41 症 例 報 告 37: 41 46, 2015 3 1 2 2 1 1 1 1 1 1 2 要 旨 1 71 15 mg 2 76 15 mg 3 3 80 10 mg 2 Xa Key words: rivaroxaban, anticoagulation therapy, intracerebral hemorrhage はじめに 2012 4 Xa ROCKET AF 0.5 vs.

More information

JCAS 対象および方法 prospective registry CEA CAS JCAS RCT 2 JCAS TIA minor stroke major stroke mrs CEA CAS 1 3 SPECT case volume CEA CAS 結果

JCAS 対象および方法 prospective registry CEA CAS JCAS RCT 2 JCAS TIA minor stroke major stroke mrs CEA CAS 1 3 SPECT case volume CEA CAS 結果 Online publication January 14, 2011 原 著 第 50 回総会シンポジウム 5 日本脳神経血管内治療学会 : 頭頸部 頭蓋内血管に対する血行再建術 本邦における頸動脈治療の前向き登録 (JCAS 研究 ) 1 1 JCAS 要旨 :JCAS 5053 1164 69.8 87 45 CAE 34 CAS 2130 major adverse events CEA 3.2

More information

提供 ブリストル マイヤーズ株式会社 ファイザー株式会社 座談会 Round Table Discussion 非弁膜症性心房細動患者の 心原性脳塞栓症予防 司会 山下 武志 公益財団法人心臓血管研究所所長 付属病院長 出席者 里見 和浩 東京医科大学八王子医療センター循環器内科准教授 三明 淳一朗 鳥取大学医学部病態情報内科学分野講師 鈴木 信也 赤尾 昌治 公益財団法人心臓血管研究所付属病院循環器内科医長

More information

_02.indd

_02.indd 30, 11-16, 2010 Z Z score Computed tomography ROC analysis 3 CT 1,2 CT 1/3 3 5 CT CT 6 7,8 MCA ASPECTS Alberta Stroke Programme Early CT Score 4 10 CT ASPECTS 50% 9 Z 10 CT Z CT 10 Z Z Z receiver operating

More information

Fig. 1 Trends of TB incidence rates for all forms and smear-positive pulmonary TB in Kawasaki City and Japan. Incidence=newly notified cases of all fo

Fig. 1 Trends of TB incidence rates for all forms and smear-positive pulmonary TB in Kawasaki City and Japan. Incidence=newly notified cases of all fo Kekkaku Vol. 79, No. 1: 17-24, 2004 17 (Received 21 Aug. 2003/Accepted 18 Nov. 2003) Fig. 1 Trends of TB incidence rates for all forms and smear-positive pulmonary TB in Kawasaki City and Japan. Incidence=newly

More information

PowerPoint プレゼンテーション

PowerPoint プレゼンテーション Journal Club 脳出血を起こした心房細動患者の抗凝固は行うべきか? 2017 年 11 月 17 日聖マリアンナ医科大学病院神経内科荒賀崇 本日の論文 JAMA Intern Med. 2017;177:563-70. 背景 用語整理 Intracranial hemorrhage (ICH) : 頭蓋内出血 1 epidural hematoma/subdural hematoma/sah

More information

BUN, CRP K mg/ cm, 49.6 kg, BMI /72 mmhg, 92/ Hb 6.7 g/dl PT-INR CT 1 MRI 2a, b T1 T2 T1 MRI

BUN, CRP K mg/ cm, 49.6 kg, BMI /72 mmhg, 92/ Hb 6.7 g/dl PT-INR CT 1 MRI 2a, b T1 T2 T1 MRI 20 2 2015 1 2 3 85 K CT Abstract A case of renal subcapsular hematoma resulting from trigger point injection under excessive effect of anticoagulant YAMANE Tateki, UMEDA Akira and SHIMAO Hitoshi An 85-year-old

More information

日本消化器外科学会雑誌第30巻第3号

日本消化器外科学会雑誌第30巻第3号 Key words : gastric cancer, progltostic factor. multivariate analysis Factors selected after Coffelation- after Stepwise rnitrally check check H o s t l A g e C O 2 S e x C O 3 Pre-op. compliation O Treatment

More information

2 はじめに 血栓症とは 140 2/3 4 DIC: disseminated intravascular coagulation 3 Virchow's triad : R. K. Virchow 表 1 各種静脈血栓症の発症要因 C S C Factor V Leiden*

2 はじめに 血栓症とは 140 2/3 4 DIC: disseminated intravascular coagulation 3 Virchow's triad : R. K. Virchow 表 1 各種静脈血栓症の発症要因 C S C Factor V Leiden* 1 総 説 血栓症治療薬の進歩 - 新しい経口抗凝固薬を中心に - 鈴木 宏治 キーワード :Xa DIC 要旨 NVAF DVT PE 3 Virchow's triad K Xa NVAF DVT PE 2 はじめに 血栓症とは 140 2/3 4 DIC: disseminated intravascular coagulation 3 Virchow's triad : R. K. Virchow

More information

Table 1 ICHs in young adults Table 2 Five cases of undetermined etiology

Table 1 ICHs in young adults Table 2 Five cases of undetermined etiology Table 1 ICHs in young adults Table 2 Five cases of undetermined etiology 神 1 1. left : in the right ted MRI, callosum. parietal. right : ICH in 保 洋 之 他 ICHs 4 Ti-weighthe 1. left: rrhagic corpus infarction

More information

Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution of female patients with blad

Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution of female patients with blad Key words: Female with bladder irritability, Subjective symptoms, Pyuria, Bacteriuria Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution

More information

九州大学学術情報リポジトリ Kyushu University Institutional Repository 高齢心疾患患者における運動機能と身体的フレイル評価の意義 内藤, 紘一九州大学大学院人間環境学府 京都橘大学健康科学部 熊谷, 秋三九州大学大学院人間環境学府 九州大学基幹教育院 九州大

九州大学学術情報リポジトリ Kyushu University Institutional Repository 高齢心疾患患者における運動機能と身体的フレイル評価の意義 内藤, 紘一九州大学大学院人間環境学府 京都橘大学健康科学部 熊谷, 秋三九州大学大学院人間環境学府 九州大学基幹教育院 九州大 九州大学学術情報リポジトリ Kyushu University Institutional Repository 高齢心疾患患者における運動機能と身体的フレイル評価の意義 内藤, 紘一九州大学大学院人間環境学府 京都橘大学健康科学部 熊谷, 秋三九州大学大学院人間環境学府 九州大学基幹教育院 九州大学キャンパスライフ 健康支援センター https://doi.org/10.15017/1800856

More information

SIZ0213責上.mcd

SIZ0213責上.mcd 日本人における新規抗凝固薬の使い分け 新規抗凝固薬使い分けのポリシー 三田村秀雄 国家公務員共済組合連合会 立川病院 なぜ使い分けが必要なのか心房細動に伴う血栓塞栓症を防ぐために抗凝固療法は欠かせない. ところが, 抗凝固薬としておよそ 50 年にわたって頻用されてきたワルファリンに代わる複数の新規抗凝固薬 NOAC が登場し, 選択肢が増えたことは好ましいとはいえ, 迷いも増えた. たとえ同じ抗凝固薬であってもどの症例にどのタイミングでどのくらいの量をどのくらいの間隔で投与するか,

More information

220 28;29) 30 35) 26;27) % 8.0% 9 36) 8) 14) 37) O O 13 2 E S % % 2 6 1fl 2fl 3fl 3 4

220 28;29) 30 35) 26;27) % 8.0% 9 36) 8) 14) 37) O O 13 2 E S % % 2 6 1fl 2fl 3fl 3 4 Vol. 12 No. 2 2002 219 239 Λ1 Λ1 729 1 2 29 4 3 4 5 1) 2) 3) 4 6) 7 27) Λ1 701-0193 288 219 220 28;29) 30 35) 26;27) 0 6 7 12 13 18 59.9% 8.0% 9 36) 8) 14) 37) 1 1 1 13 6 7 O O 13 2 E S 1 1 17 0 6 1 585

More information

2 The Bulletin of Meiji University of Integrative Medicine 3, Yamashita 10 11

2 The Bulletin of Meiji University of Integrative Medicine 3, Yamashita 10 11 1-122013 1 2 1 2 20 2,000 2009 12 1 2 1,362 68.1 2009 1 1 9.5 1 2.2 3.6 0.82.9 1.0 0.2 2 4 3 1 2 4 3 Key words acupuncture and moxibustion Treatment with acupuncture, moxibustion and Anma-Massage-Shiatsu

More information

Web Stamps 96 KJ Stamps Web Vol 8, No 1, 2004

Web Stamps 96 KJ Stamps Web Vol 8, No 1, 2004 The Journal of the Japan Academy of Nursing Administration and Policies Vol 8, No 1, pp 43 _ 57, 2004 The Literature Review of the Japanese Nurses Job Satisfaction Research Which the Stamps-Ozaki Scale

More information

ディスカッションの目的と背景 2

ディスカッションの目的と背景 2 第 5 回 DSRT 医薬品の臨床試験および製造販売後調査におけるベイズ統計学の活用について 議題 5:PIII 非劣性試験における ベイズ統計学の利用可能性 ( 予習資料 ) 1 ディスカッションの目的と背景 2 議論の背景と目的 背景 : 医薬品開発において非劣性試験を行う場合, 以下の状況が想定できると考える 実対照群の 有効性に対する情報 が十分に蓄積されている 実対照群の 有効性に対する情報

More information

HEART'S Original A case of Brugada syndrome with a high defibrillation threshold in which defibrillation was successful by Active Can off defibrillation Keisuke Kawachi, Yukei Higashi, Yuuki Honda, Kouhei

More information

Clinical Study of Effect of Intrathecal Use of Alpha-tocopherol on Chronic Vasospasm Hirotoshi Sano, Motoi Shoda, Youko Kato, Kazuhiro Katada, Youichi

Clinical Study of Effect of Intrathecal Use of Alpha-tocopherol on Chronic Vasospasm Hirotoshi Sano, Motoi Shoda, Youko Kato, Kazuhiro Katada, Youichi Clinical Study of Effect of Intrathecal Use of Alpha-tocopherol on Chronic Vasospasm Hirotoshi Sano, Motoi Shoda, Youko Kato, Kazuhiro Katada, Youichi Shinomiya and Tetsuo Kanno Department of Neurosurgery,

More information

52-2.indb

52-2.indb Jpn. J. Health Phys., 52 (2) 55 60 (2017) DOI: 10.5453/jhps.52.55 * 1 * 2 * 2 * 3 * 3 2016 10 28 2017 3 8 Enhancement of Knowledge on Radiation Risk Yukihiko KASAI,* 1 Hiromi KUDO,* 2 Masahiro HOSODA,*

More information

The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursi

The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursi The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursing Professionals for Diabetic Outpatients Not Using

More information

A Nutritional Study of Anemia in Pregnancy Hematologic Characteristics in Pregnancy (Part 1) Keizo Shiraki, Fumiko Hisaoka Department of Nutrition, Sc

A Nutritional Study of Anemia in Pregnancy Hematologic Characteristics in Pregnancy (Part 1) Keizo Shiraki, Fumiko Hisaoka Department of Nutrition, Sc A Nutritional Study of Anemia in Pregnancy Hematologic Characteristics in Pregnancy (Part 1) Keizo Shiraki, Fumiko Hisaoka Department of Nutrition, School of Medicine, Tokushima University, Tokushima Fetal

More information

indd

indd 12 61 1 2011 原著 1)2)5) 1) 1)2) 1)2)5) 1)3)5) 1)2) 1)2)5) 1)2) 1)2) 2) 2) 4) 1) 1) 2) 3) 4) 5) 2010 10 6 2010 12 6 A Comparative Study of the Effect and Discomfort Produced by Pharyngeal Anesthesia with

More information

udc-2.dvi

udc-2.dvi 13 0.5 2 0.5 2 1 15 2001 16 2009 12 18 14 No.39, 2010 8 2009b 2009a Web Web Q&A 2006 2007a20082009 2007b200720082009 20072008 2009 2009 15 1 2 2 2.1 18 21 1 4 2 3 1(a) 1(b) 1(c) 1(d) 1) 18 16 17 21 10

More information

1) i) Barber, M. et al.: Brit. Med J, 2, 565, 19'49. ii) Barber, M.F.G. J. Hayhoe and J. E. M. Whithead: Lancet, 1120 `1125, 1949.-2) Bergey: Bergey's Manual of Determinative Bacteriology 7 th Ed: (1958).-3)

More information

2012 Vol. 23 No pseudothrombophlebitis pseudothrombophlebitis

2012 Vol. 23 No pseudothrombophlebitis pseudothrombophlebitis pseudothrombophlebitis 5 424 163 38.1 26 6.1 5 1.2 230 2 3 66.4 51 80 2 3 2 2 1 2012 23 3 261-265 pseudothrombophlebitis 1 2011 7 11 30 2010 2 5 47 Fig. 1 Ultrasonography showed a low echoic cyst in the

More information

3) Narula OS, Samet P, Javier RP: Significance of the Sinus-Node Recovery Time. Circulation 45: 140-158, 1972. 4) Dreifus LS, Michelson EL, Kaplinsky E: Bradyarrhythmias: Clinical Significance and Management.

More information

大学論集第42号本文.indb

大学論集第42号本文.indb 42 2010 2011 3 279 295 COSO 281 COSO 1990 1 internal control 1 19962007, Internal Control Integrated Framework COSO COSO 282 42 2 2) the Committee of Sponsoring Organizations of the Treadway committee

More information

THE JAPANESE JOURNAL OF PERSONALITY 2007, Vol. 15 No. 2, 217–227

THE JAPANESE JOURNAL OF PERSONALITY 2007, Vol. 15 No. 2, 217–227 2007 15 2 217 227 2007 1 2 445 238 207 1 7 7 (2005) (2005) (2006a) 2006a (2004) (assumed-competence) 218 15 2 1 2005 2004 (2004) (2004) (2004) 16PF (2006) 4 Hayamizu, 2002 2006a (2006a) 1 Hayamizu, Kino,

More information

JC38608

JC38608 J Cardiol 2001 Dec; 38 6 : 327 335 % 1 1 1 2 2 3 4 Relationship Between Prothrombin Time International Normalized Ratio and Thrombo Test % Yuichi Yasuhiro Kenshiro Yutaka Tomio Hiroshi Hiroshi Takeshi

More information

Noninvasive estimation of pulmonary capillary wedge pressure and cardiac output by the analysis of pulmonary venous flow velocity patterns in patients

Noninvasive estimation of pulmonary capillary wedge pressure and cardiac output by the analysis of pulmonary venous flow velocity patterns in patients Noninvasive estimation of pulmonary capillary wedge pressure and cardiac output by the analysis of pulmonary venous flow velocity patterns in patients with acute congestive heart failure Jung-Myung Lee,

More information

本文.indd

本文.indd CQ ACC/AHA PECO PatientExposure Comparison OutcomePECO low-density lipoprotein cholesterol LDL C cholesterol cholesterol intensive OR agressive CQ target LDL C PubMed Systematic Reviews Clinical Study

More information

PowerPoint プレゼンテーション

PowerPoint プレゼンテーション Clinical Question 2014.8.25 JHOSPITALIST Network 冠動脈ステント留置後の患者に心房細動が起きたら抗血小板薬に抗凝固薬を併用した方がよいのか? 亀田総合病院総合内科小菅理紗 監修佐田竜一 佐藤暁幸 分野 : 循環器テーマ : 治療 引き継ぎ初診外来 ~78 歳男性 ~ いやぁ 新しい先生だからドキドキしちゃうねぇ 血圧 117/68mmHg 脈拍 78

More information

研究紀要52号(よこ)人間科学☆/1.垂沢

研究紀要52号(よこ)人間科学☆/1.垂沢 Comparative study of images related to plump and fat in Japan TARESAWA Yumiko, TAKEUCHI Misaki and TSUJIMOTO Yui Abstract : Ever since a fashion magazine for plump women was first published in March 2013,

More information

The Nutrient Intake of Young Women With Special Attention on the Trace Nutrients Including Folate SUZUKI Kazu', HIGASHINE Yuuko", ITOU Ryoko YAMADA Yukiko', KOSEKI Sakiyo*, OKUDA Toyoko"" Seibo Jogakuin

More information

Studies of Foot Form for Footwear Design (Part 9) : Characteristics of the Foot Form of Young and Elder Women Based on their Sizes of Ball Joint Girth

Studies of Foot Form for Footwear Design (Part 9) : Characteristics of the Foot Form of Young and Elder Women Based on their Sizes of Ball Joint Girth Studies of Foot Form for Footwear Design (Part 9) : Characteristics of the Foot Form of Young and Elder Women Based on their Sizes of Ball Joint Girth and Foot Breadth Akiko Yamamoto Fukuoka Women's University,

More information

1272 CHEMOTHERAPY MAR. 1975

1272 CHEMOTHERAPY MAR. 1975 1272 CHEMOTHERAPY MAR. 1975 VOL. 23 NO. 3 CHEMOTHERAPY 1273 Fig. 2 Minimal inhibitory concentration of aminoglycosides against 50 strains of Klebsiella Fig. 1 Minimal inhibitory concentration of aminoglycosides

More information

H29_第40集_大和証券_研究業績_C本文_p indd

H29_第40集_大和証券_研究業績_C本文_p indd 慢性腎臓病 (CKD) における危険因子としての食後高血糖の検討 独立行政法人国立病院機構千葉東病院臨床研究部 糖尿病研究室長関直人 はじめに 1. 研究の背景慢性腎臓病 (CKD) は 動脈硬化 腎機能低下 末期腎不全 心血管イベントなどの危険因子であることが報告されている (1) 一方で食後高血糖もまた 動脈硬化 心血管イベントの危険因子であることが報告されている (2) 食後高血糖の検出には持続血糖モニタリング

More information

静 脈 学 Table 1 Patient characteristics Symptom Case Age Sex Site PE Cause Treatment 1 44 M RSCV swelling (+) unknown UK, anticoaglant patent Result 2 5

静 脈 学 Table 1 Patient characteristics Symptom Case Age Sex Site PE Cause Treatment 1 44 M RSCV swelling (+) unknown UK, anticoaglant patent Result 2 5 Paget-Schroetter 3 Paget-Schroetter 3 1 1 1 3 86 42 Paget-Schroetter 2013 24 1 71- Paget-Schroetter 3 Table 1 1 44 1 CT 1 2012 4 19 CT CT Fig. 1 2 54 CT Fig. 2 71 静 脈 学 Table 1 Patient characteristics

More information

840 Geographical Review of Japan 73A-12 835-854 2000 The Mechanism of Household Reproduction in the Fishing Community on Oro Island Masakazu YAMAUCHI (Graduate Student, Tokyo University) This

More information

食道がん化学放射線療法後のsalvage手術

食道がん化学放射線療法後のsalvage手術 2006 2 17 52 Daly JM, et al. J Am Coll Surg 2000;190:562-573 Esophageal Cancer: Results of an American College of Surgeons Patient Care Evaluation Study Daly JM, et al. J Am Coll Surg 2000;190:562-573

More information

Title 泌尿器科領域に於ける17-Ketosteroidの研究 17-Ketosteroidの臨床的研究 第 III 篇 : 尿 Author(s) 卜部, 敏入 Citation 泌尿器科紀要 (1958), 4(1): 3-31 Issue Date URL

Title 泌尿器科領域に於ける17-Ketosteroidの研究 17-Ketosteroidの臨床的研究 第 III 篇 : 尿 Author(s) 卜部, 敏入 Citation 泌尿器科紀要 (1958), 4(1): 3-31 Issue Date URL Title 泌尿器科領域に於ける17-Ketosteroidの研究 17-Ketosteroidの臨床的研究 第 III 篇 : 尿 Author(s) 卜部, 敏入 Citation 泌尿器科紀要 (1958), 4(1): 3-31 Issue Date 1958-01 URL http://hdl.handle.net/2433/111559 Right Type Departmental Bulletin

More information

untitled

untitled JAIS 1 2 1 2 In this paper, we focus on the pauses that partly characterize the utterances of simultaneous interpreters, and attempt to analyze the results of experiments conducted using human subjects

More information

J. Jpn. Acad. Nurs. Sci., Vol.25, No.1, pp.13-22, 2005 Decision Making under the Uncertainty; Process of Decision from Diagnosis to Preventive- Operat

J. Jpn. Acad. Nurs. Sci., Vol.25, No.1, pp.13-22, 2005 Decision Making under the Uncertainty; Process of Decision from Diagnosis to Preventive- Operat J. Jpn. Acad. Nurs. Sci., Vol.25, No.1, pp.13-22, 2005 Decision Making under the Uncertainty; Process of Decision from Diagnosis to Preventive- Operation in Patient with Asymptomatic Cerebrovascular Diseases

More information

脈管学55巻11号 pp

脈管学55巻11号 pp Online publication December 10, 2015 191 原 著 55 21 1 2 2 1 2 2 2 2 1 要旨 : 8 21 19 2 4 1 20 SMA short segment J Jpn Coll Angiol 2015; 55: 191 196 Key words: superior mesenteric artery, dissection, conservative

More information

Table 1 Patients with various renal function * Ccr, Creatinine clearance ml/min per 1. 48 m2 ** C.V.D., Cerebral vascular disease ; C.R F., Chronic renal failure ; H.D., Hemoclialysis ; D., Dialyzer ;

More information

ROCKY NOTE 脳梗塞に対するアスピリンとクロピドグレルの併用 :CHANCE MATCH SPS3 (130812) 脳外志望の研修医と一緒に抄読会 脳梗塞に対する抗血小板剤併用の効果を検討した論文を

ROCKY NOTE   脳梗塞に対するアスピリンとクロピドグレルの併用 :CHANCE MATCH SPS3 (130812) 脳外志望の研修医と一緒に抄読会 脳梗塞に対する抗血小板剤併用の効果を検討した論文を 脳梗塞に対するアスピリンとクロピドグレルの併用 :CHANCE MATCH SPS3 (130812) 脳外志望の研修医と一緒に抄読会 脳梗塞に対する抗血小板剤併用の効果を検討した論文を 読んだ PECO P:5170 patients within 24 hours after the onset of minor ischemic stroke or high-risk TIA E:combination

More information

Title

Title Clinical question 2014 年 7 月 28 日 JHOSPITALIST Network 左室収縮障害を伴う広範な前壁中隔梗塞では 左室内血栓が無くても抗凝固療法を行うべきか 東京ベイ 浦安市川医療センター福井悠 監修山田徹 分野 : 循環器テーマ : 治療 高血圧 高脂血症 喫煙歴のある 62 歳男性 胸痛で受診 心電図で前壁中隔誘導のST 上昇 アスピリン200mg クロピドグレル300mgが投与され

More information

JHN Journal Club 手稲渓仁会病院

JHN Journal Club 手稲渓仁会病院 JHOSPITALIST network GUIDE-IT trial; The Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure multicentre randomised clinical trial 20171010 1 70 (EF 30%), (PCI), (HbA1c

More information

2 10 The Bulletin of Meiji University of Integrative Medicine 1,2 II 1 Web PubMed elbow pain baseball elbow little leaguer s elbow acupun

2 10 The Bulletin of Meiji University of Integrative Medicine 1,2 II 1 Web PubMed elbow pain baseball elbow little leaguer s elbow acupun 10 1-14 2014 1 2 3 4 2 1 2 3 4 Web PubMed elbow pain baseball elbow little leaguer s elbow acupuncture electric acupuncture 2003 2012 10 39 32 Web PubMed Key words growth stage elbow pain baseball elbow

More information

Microsoft Word - 「黄砂とその健康影響について」小冊子180323版

Microsoft Word - 「黄砂とその健康影響について」小冊子180323版 ...1...1...1...2...4...4...4...6...7...7...7...7...8...8...9...9...10... 11... 11... 11... 11...12...12...13...16...18...20 1 1-1 1-2 1 1 km 24.5 m/s 10 50 m 1 1-3 μm 1-4 1-5 2 8 http://www.jma-net.go.jp/sat/himawari/obsimg/image_dust.html

More information

29 表4. 図1. 左 室 流 入 血 流 速 パ タ ー ン(パ エ コ ー 図)の 異 常 例 長期 透析 患者 の 高血圧群 と透析 時低血 圧群 に お け る心 エ コー図検 査成 績 ル ス ドプ ラ ー心 よ び低 血 圧 を伴 い,HCM様 症 例 は10例(31%)で が 高 血 圧 で あ った 両 群 で のDCMお よびHCM様 例 の 出 現 頻 度 に 差 は な か

More information

04_学術.indd

04_学術.indd Arts and Sciences About a Human Error prevention countermeasure based on Human Factors and Cognitive Psychology. 30178 Key words: Human Factors, Ergonomics, Cognitive Psychology, Risk management, Human

More information

...v.q.....r .C

...v.q.....r          .C March Cooper Medical College Sacrament Webster March March March March Kuakini Medical Center Young Men s Buddhist Association YMCA March March March March Eriko Yamamoto, THE EVOLUTION OF AN ETHNIC

More information

7,, i

7,, i 23 Research of the authentication method on the two dimensional code 1145111 2012 2 13 7,, i Abstract Research of the authentication method on the two dimensional code Karita Koichiro Recently, the two

More information

IR0036_62-3.indb

IR0036_62-3.indb 62 3 2016 253 272 1921 25 : 27 8 19 : 28 6 3 1921 25 1921 25 1952 27 1954 291960 35 1921 25 Ⅰ 0 5 1 5 10 14 21 25 34 36 59 61 6 8 9 11 12 16 1921 25 4 8 1 5 254 62 3 2016 1 1938.8 1926 30 1938.6.23 1939.9

More information

8 The Bulletin of Meiji University of Integrative Medicine API II 61 ASO X 11 7 X-4 6 X m 5 X-2 4 X 3 9 X 11 7 API 0.84 ASO X 1 1 MR-angio

8 The Bulletin of Meiji University of Integrative Medicine API II 61 ASO X 11 7 X-4 6 X m 5 X-2 4 X 3 9 X 11 7 API 0.84 ASO X 1 1 MR-angio 7-14 2010 1 1 1 2 1 1 1 2 Fontaine II ASO61 3 API ASO ASO ASO API API KKKKKKKKKK ASO Fontaine II API Received April 14, 2009; Accepted July 16, 2009 I arteriosclerosis obliterans: ASO ASO 50 70 1,2 Fontaine

More information

I

I 九州大学学術情報リポジトリ Kyushu University Institutional Repository 熊本県水俣市の限界集落における耕作放棄地の拡大とその要因 寺床, 幸雄九州大学大学院人文科学府 : 博士後期課程 : 農村 農業地理学 Teratoko, Yukio http://hdl.handle.net/2324/20036 出版情報 : 地理学評論. 82 (6), pp.588-603,

More information

1) Tatelman M: The angiographic evaluation of cerebral arteriosclerosis. Radiology 70: 801-810, 1958. 2) Elkeles A: A comparative study of calcified 8) Limpert JD, Vogelzang RL, Yao JST: Computed tomography

More information

Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic c

Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic c Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic clinic, Department of Ophthalmology, (Director: Prof

More information

東洋医学雑誌

東洋医学雑誌 Vol.67 No.2 123-130, 2016 Akiyo GUSHI a Chihaya KORIYAMA b Ryo YOSHINAGA c Hiromi YANO c Junichi TSUMAGARI d Eiichi TAHARA c a Gushi Dermatological Clinic, 45-3 Higashiohsyoji, Satsumasendai city, Kagoshima

More information

IPSJ SIG Technical Report Vol.2016-CE-137 No /12/ e β /α α β β / α A judgment method of difficulty of task for a learner using simple

IPSJ SIG Technical Report Vol.2016-CE-137 No /12/ e β /α α β β / α A judgment method of difficulty of task for a learner using simple 1 2 3 4 5 e β /α α β β / α A judgment method of difficulty of task for a learner using simple electroencephalograph Katsuyuki Umezawa 1 Takashi Ishida 2 Tomohiko Saito 3 Makoto Nakazawa 4 Shigeichi Hirasawa

More information

Journal Club 2017/05/30 Tomohiro Matsumoto PGY-2

Journal Club 2017/05/30 Tomohiro Matsumoto PGY-2 Journal Club 2017/05/30 Tomohiro Matsumoto PGY-2 本 の論 March 21, 2017 2 Introduc)on 3 : (CIN) 3 25% 44µmol/L(0.5mg/dL) CIN 4 European Society of Urogenital Radiology. ESUR guidelines on contrast media,

More information

Financing through Stadium Securitization \ Case Study of Professional Football Clubs in England \ õ Yoshiaki IIDA * Abstract The purpose of this study was to clarify the way in which the stadium securitization

More information

スライド 1

スライド 1 1 2006 msv 2 2011 3 CT 2011 10mSv 10 40mSv 4 2012 217mSv 5 (CT) 2012 50 60mSv 6 2012 510mSv BRCA25 310 10mSv3% BRCA60-280% 3 5m Sv 1m Sv 12% . http://www.rea.or.jp/ire/pdf/report4.pdf 1.10 20 SMR 1.00

More information

PDFfl[ŁiŠp_Œ{Ł¶…g…fi…{Łt‡«.pdf

PDFfl[ŁiŠp_Œ{Ł¶…g…fi…{Łt‡«.pdf 診断 治療 技術講座 2018; 29 4 : 413-420 APTT 波形解析 APTT waveform Hideo WADA Key words: APTT, waveform, hemophilia, anticoagulant therapy 1978 1982 1982 1983 1985 NIH 1985 2000 / 2008 1 activated partial thromboplastin

More information

MV X 5 6 Common Terminology Criteria for Adverse Events Grade 1 Grade Gy 16 QOL QOL 5 6 7, 8 9, VOL.3 NO

MV X 5 6 Common Terminology Criteria for Adverse Events Grade 1 Grade Gy 16 QOL QOL 5 6 7, 8 9, VOL.3 NO 乳がん患者の放射線皮膚炎に対するスキンケアの指導の実際 がん放射線療法看護認定看護師とがん放射線治療に携わる看護師との比較 Educating practice of skin care for radiodermatitis of breast cancer patients: Comparison of the nurses with certified nurse in radiation therapy

More information

2001 2003 2005 2006 2007 2008

2001 2003 2005 2006 2007 2008 2001 2003 2005 2006 2007 2008 60 etc. http://nosmoke.hp.infoseek.co.jp/yuugaibussitu.htm http://nosmoke.hp.infoseek.co.jp/yuugaibussitu.htm 23.5% 2.8% 2.8% 3.4% 30.3% 9.9% 11.5% 15.8% AAN 65

More information

IPSJ SIG Technical Report Secret Tap Secret Tap Secret Flick 1 An Examination of Icon-based User Authentication Method Using Flick Input for

IPSJ SIG Technical Report Secret Tap Secret Tap Secret Flick 1 An Examination of Icon-based User Authentication Method Using Flick Input for 1 2 3 3 1 Secret Tap Secret Tap Secret Flick 1 An Examination of Icon-based User Authentication Method Using Flick Input for Mobile Terminals Kaoru Wasai 1 Fumio Sugai 2 Yosihiro Kita 3 Mi RangPark 3 Naonobu

More information

ABSTRACT The Social Function of Boys' Secondary Schools in Modern Japan: From the Perspectives of Repeating and Withdrawal TERASAKI, Satomi (Graduate School, Ochanomizu University) 1-4-29-13-212, Miyamaedaira,

More information

Endocrinological and statistical analysis of ovarian function in hysterectomized patients Masaya HAYAFUJI, Kazuaki KATAYAMA and Matsuto MOCHIZUKI Depa

Endocrinological and statistical analysis of ovarian function in hysterectomized patients Masaya HAYAFUJI, Kazuaki KATAYAMA and Matsuto MOCHIZUKI Depa Endocrinological and statistical analysis of ovarian function in hysterectomized patients Masaya HAYAFUJI, Kazuaki KATAYAMA and Matsuto MOCHIZUKI Department of Obstetrics and Gynecology, Kobe University

More information

yasi10.dvi

yasi10.dvi 2002 50 2 259 278 c 2002 1 2 2002 2 14 2002 6 17 73 PML 1. 1997 1998 Swiss Re 2001 Canabarro et al. 1998 2001 1 : 651 0073 1 5 1 IHD 3 2 110 0015 3 3 3 260 50 2 2002, 2. 1 1 2 10 1 1. 261 1. 3. 3.1 2 1

More information

11_渡辺_紀要_2007

11_渡辺_紀要_2007 56 1 19 Bull. Nara Univ. Educ., Vol. 56, No.1 (Cult. & Soc.), 2007 115 19 Why is Kidney Dysfunction Caused by Cadmium (Cadmium Nephropathy) not Officially Recognized as a Pollution-related Disease by the

More information

9 1, , , 2002, 1998, 1988,

9 1, , , 2002, 1998, 1988, J. Japan Soc. Hydrol. & Water Resour. Vol. 20, No.1, Jan. 2007 pp. 34-46 Dushmanta, Srikantha, 2004 "basin wide integrated flood management strategy" IV.2.50 9 1,893 333 3 528 109 54, 1987 50 9, 2002,

More information

,,.,,.,..,.,,,.,, Aldous,.,,.,,.,,, NPO,,.,,,,,,.,,,,.,,,,..,,,,.,

,,.,,.,..,.,,,.,, Aldous,.,,.,,.,,, NPO,,.,,,,,,.,,,,.,,,,..,,,,., J. of Population Problems. pp.,.,,,.,,..,,..,,,,.,.,,...,.,,..,.,,,. ,,.,,.,..,.,,,.,, Aldous,.,,.,,.,,, NPO,,.,,,,,,.,,,,.,,,,..,,,,., ,,.,,..,,.,.,.,,,,,.,.,.,,,. European Labour Force Survey,,.,,,,,,,

More information

A Study on Life-Table based on the Death Rate from a Specific Disease by Fumio Nakamura, M. D. Department of Hygiene Okayama University Medical School (Director: Professor Masahiko O. D., M. P. H.) In

More information

‹Àfi¡‚¾”O/…_…C…W…F…X…g/01-01

‹Àfi¡‚¾”O/…_…C…W…F…X…g/01-01 2002 2003 Guidelines for the Diagnosis,Treatment and Prevention of Pulmonary Thromboembolism and Deep Vein Thrombosis (JCS 2004) h 1 2 3 1 1 2 2-1 2-2 2-3 2-4 2-5 2-6 2 1 2 2-1 2-2 3 1 2 4 Circulation

More information

22 1,936, ,115, , , , , , ,

22 1,936, ,115, , , , , , , 21 * 2 3 1 1991 1945 200 60 1944 No. 41 2016 22 1,936,843 1945 1,115,594 1946 647,006 1947 598,507 1 60 2014 501,230 354,503 5 2009 405,571 5 1 2 2009 2014 5 37,285 1 2 1965 10 1975 66 1985 43 10 3 1990

More information

indd

indd 24 61 1 2011 調査 研究 1 2 1 1 2 4 1 3 4 1 2 1 2 1 2 1 2 2 1 1 2 3 4 2010 11 11 2011 1 7 Infection Control in an Endoscopy Room Multi - society Guideline and Current Status at Fukushima Medical University

More information

SUMMARY There might be no other business that has high uncertainty like Live Entertainment Business. This is because the success and failure of this business depend a great deal on the unscientific element

More information

CHEMOTHERAPY AUG. 1982 VOL. 30 NO. 8 CHEMOTHERAPY Fig.1 Relation between various-closis of cefazolin and detection rate of organisms in heart blood of dying mice with E. coli and P. aeruginosa infection

More information

Special IssueDiagnoses and therapeutic agents for age-related diseases Reviews Original Case reports β Medicinal drugs affecting on clinical laboratory blood test results and adverse effects of them

More information

JSACHD_Vol4_No2_Dec2015.book

JSACHD_Vol4_No2_Dec2015.book 4 2 30 35 (2015 ) cyanotic congenital heart disease, compensated erythrocytosis, iron replacement therapy ( 1) Hb = 57.5 (0.444 x ) 1) 1 2 30 (2015 12 ) SpO2 < 75% 2 (Ht) 2) Ht 3) QOL 4) MCV MCH TIBC Ht

More information

Table 1 Isolated venous thrombi in soleal muscle by ultrasonography US finding Acute Chronic Total No. Early stage non-retracted slightl

Table 1 Isolated venous thrombi in soleal muscle by ultrasonography US finding Acute Chronic Total No. Early stage non-retracted slightl Online publication October 8, 2010 原 著 第 50 回総会座長推薦論文 孤立性ひらめ筋内静脈血栓と抗核抗体との関連 1 2 要旨 : 89 116 D 3 30 70 63 26 100 J Jpn Coll Angiol, 2010, 50: 417 422 Key words: isolated soleal venous thrombi, recurrent

More information

20 Japanese Journal of Educational Psychology, 1989, 37, 20 \28 THE WILLINGNESS OF SELF-DISCLOSURE AND THE DEVIATION FROM NORMATIVE SELF-DISCLOSURE IN

20 Japanese Journal of Educational Psychology, 1989, 37, 20 \28 THE WILLINGNESS OF SELF-DISCLOSURE AND THE DEVIATION FROM NORMATIVE SELF-DISCLOSURE IN 20 Japanese Journal of Educational Psychology, 1989, 37, 20 \28 THE WILLINGNESS OF SELF-DISCLOSURE AND THE DEVIATION FROM NORMATIVE SELF-DISCLOSURE IN DISCLOSURE SITUATIONS Kimihisa ENDO This report proposed

More information