馬5-心房細動（7005）.indd
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1 解説 報告 日本における競走馬医療の現状 (Ⅴ) 競走馬における心房細動 大村一 ( 日本中央競馬会競走馬総合研究所運動科学研究室主任研究役 ) 1 はじめに 2 心房細動 P f R 3 馬の心房細動 Lewis f 波 1s AB P f QRS FAX hajime@equinst.go.jp
2 6 競走馬の心房細動の疫学調査 4 レース中の心房細動 Deem,. Reef,,...,.,., m, m, m 5 発作性心房細動と持続性心房細動..., 271
3 (%) ,200m 以下 1,201 ~ 1,600m 1,601 ~ 2,000m.. 7 馬の心房細動の治療 2,001 ~ 2,400m 2,401m 以上 Vaughan-Williams Ia Ic I Ia Ic.,. (1) キニジンによる治療 mg/kg mg/kg QRS QRS 272
4 (2) フレカイニドによる治療, mg/ kg mg/kg mg/kg QRS QRS 8 おわりに 参考文献 Allessie MA, Bonke FI, Schopman FJ : Circus movement in rabbit atrial muscle as a mechanism of tachycardia. III. The leading circle concept: a new model of circus movement in cardiac tissue without the involvement of an anatomical obstacle, Circ Res,, Ikeda T, Uchida T, Hough D, Lee JJ, Fishbein MC, Mandel WJ, Chen PS, Karagueuzian HS : Mechanism of spontaneous termination of functional reentry in isolated canine right atrium. Evidence for the presence of an excitable but nonexcited core, Circulation, Rensma PL, Allessie MA, Lammers WJ, Bonke FI, Schalij MJ : Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs, Circ Res,, Holmes JR : The equine heart, Problems and difficulties in assessing cardiac function on clinical examination, Equine Vet J,, Lewis T : Irregularity of the heart s action in horse and its relationship to fibrillation of the auricles in experiment and to complete irregularity of the human heart, Heart,, Kuwahara M, Hiraga A, Nishimura T, Tsubone H, Sugano S : Electrocardiogram from the Longest-Living Racehorse in Japan: Legendary Racehorse Shinzan, J Equine Sci,, Amada A, Senta T, Kubo K, Oh-ishi S, Kiryu K : Atrial fibrillation in the horse: Clinical and histopathological studies of two cases, : Clinical study, Exp Rep Equine Health Lab,, Amada A, Kurita H : Five cases of paroxysmal atrial fibrillation in the racehorse, Exp Rep Equine Health Lab,, Holmes JR, Henigan M, Williams RB, Witherington DH : Paroxysmal atrial fibrillation in racehorses, Equine Vet J,, Holmes JR : Arrhythmia on the racehorse. In: Equine Exerc. Physiol.. Eds: J.R. Gillespie and N.E. Robinson, ICEEP Publications, Davis, California, Deem DA, Fregin GE : Atrial fibrillation in horses: A review of clinical cases, with consideration of prevalence, clinical signs, and prognosis, J Am Vet Med Assoc,, Reef VB, Levitan CW, Spencer PA : Factors affecting prognosis and conversion in equine atrial fibrillation, J Vet Intern Med, 273
5 Reef VB, Reimer JM, Spencer PA : Treatment of atrial fibrillation in horses: New perspectives, J Vet Intern Med,, Ohmura H, Hiraga A, Takahashi T, Kai M, Jones JH : Risk factors for atrial fibrillation during racing in slow-finishing horses, J Am Vet Med Assoc,, Takahashi T, Hiraga A, Ohmura H, Kai M, Jones JH : Frequency of and risk factors for epistaxis associated with exercise-induced pulmonary hemorrhage in horses:, race starts ( ), J Am Vet Med Assoc,, Amada A Kurita H : Treatment of atrial fibrillation with quinidine sulfate in the racehorse, Exp Rep Equine Health Lab,, Bertone JJ, Traub Dargatz JL, Wingfield WE : Atrial fibrillation in a pregnant mare: treatment with quinidine sulfate, J Am Vet Med Assoc, Glendinning SA : The use of quinidine sulphate for the treatment of atrial fibrillation in twelve horses, Vet Rec, Gerber H, Chuit P, Schatzmann HJ : Treatment of atrial fibrillation in the horse with intravenous dihydroquinidine gluconate, Equine Vet J,, Lekeux P, Muylle E, Henroteaux M, Bienfet V : Comparison of different treatments of atrial fibrillation in the horse, Zentralbl Veterinarmed,, Morris DD, Fregin GF : Atrial fibrillation in horses: factors associated with response to quinidine sulfate in clinical cases, Cornell Vet,, Muir WW, McGuirk S : Cardiovascular drugs, Vet Clin Nor Am,, McGurrin MKJ, Physick-Sheard PW, Kenney DG : How to perform transvenous electrical cardioversion in horses with atrial fibrillation, J Vet Cardiol,, McGurrin M, Physick-Sheard P, Kenney D : Transvenous electrical cardioversion of equine atrial fibrilla- tion: patient factors and clinical results in treatment episodes, J Vet Intern Med,, Risberg ÅI, McGuirk SM : Successful conversion of equine atrial fibrillation using oral flecainide, J Vet Intern Med,, Takahashi Y, Ishikawa Y, Ohmura H : Treatment of recent-onset atrial fibrillation with quinidine and flecainide in Thoroughbred racehorses; cases ( ), J Am Vet Med Assoc (in Press) Ohmura H, Hiraga A, Aida H, Kuwahara M, Tsubone H : Effects of repeated atropine injection on heart rate variability in Thoroughbred horses, J Vet Med Sci,, McGuirk SM, Muir WW, Sams RA : Pharmacokinetic analysis of intravenously and orally administered quinidine in horses, Am J Vet Res,, Ohmura H, Nukada T, Mizuno Y, Yamaya Y, Nakayama T, Amada A : Safe and efficacious dosage of flecainide acetate for treating equine atrial fibrillation, J Vet Med Sci,, Ohmura H, Hiraga A, Aida H, Takahashi T, Nukada T : Determination of oral dosage and pharmacokinetic analysis of flecainide in horses, J Vet Med Sci,, Loon GV, Blissitt K, Keen J, Young LE : Use of intravenous flecainide in horses with naturally-occurring atrial fibrillation, Equine Vet J,, Birettoni F, Porciello F, Rishniw M, della Rocca G, Di Salvo A, Sgorbini M : Treatment of chronic atrial fibrillation in the horse with flecainide: personal observation, Vet Res Commun,, Dembek KA, Hurcombe SD, Schober KE, Toribio RE : Sudden death of a horse with supraventricular tachycardia following oral administration of flecainide acetate, J Vet Emerg Crit Care,, Kubo K, Senta T, Sugimoto O : Changes in cardiac output with experimantally induced atrial fibrillation the horse, Exp Rep Equine Health Lab, Jpn J Electrocardiology Suppl 274
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