79 +.* + 1/* A +
80, E + + Bioaccessibility +,
81,. 0* nm bo, Caco-, +* - -
82 - Caco, + Pow +, b-carotene ;,, a-carotene ; -, b-cryptoxanthin ;., lutein ; /, zeaxanthin ; 0, canthaxanthin ; 1, astaxanthin ; 2, violaxanthin ; 3, neoxanthin ; +*, fucoxanthin B + SR- BI. Caco-,
83. Caco-, PC, ; LPC, Caco-, -. / HLB,
84 0 bo bo ao 1 /,** g ; 20. mg bo +-.. mg
85 / HPLC ; ; R-Nc, ( 2R)-Neochrome ; S-Nc, ( 2S)- Neochrome ; Nxn, Neoxanthin 0/. mg -*. mg bo / / in vitro 2 3 bo
86 - A A khachik 2 -oob eoo-o -o oe eoo-o e eoo- -o 0.. o obo
87 0 +* A - NAD 1 HepG, A A
88 1. A bo +/ +/ BCO+ ++, +,, 2 A A
89 2 +- A A A +. 3 +* BCO, bo A bo 2 in vivo 3 +* + 3 +*
90 3 bo boo Tween.* 3
91 3 +* -oobo 3 +* -oo+. o +. +- +. Cobo +. boo2o C 2 +, bo bo b b,*,* + +/ +*,* + /
92 +* + Yonekura, L., Nagao, A. (,**1) Intestinal absorption of dietary carotenoids, Mol. Nutr. Food Res. /+ : +*1 ++/., Ryan, L., O Connell, O., O Sullivan, L., Aherne, S.A., O Brien, N.M. (,**2) Micellarisation of carotenoids from raw and cooked vegetables, Plant Food Hum. Nutr. 0- : +,1 +--. - Sugawara, T., Kushiro, M., Zhang, H., Nara, E., Ono, H., Nagao, A. (,**+) Lysophosphatidylcholine enhances carotenoid uptake from mixed micelles by Caco-, human intestinal cells, J. Nutr. +-+ :,3,+,3,1.. van Bennekum, A., Werder, M., Thuahnai, S.T., Han, C.H., Duong, P., Williams, D.L., Wettstein, P., Schulthess, G., Phillips, M.C., Hauser, H. (,**/) Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol, Biochemistry.. :./+1./,/. / Yonekura, L., Tsuzuki, W., Nagao, A. (,**0) Acyl moieties modulate the e# ects of phospholipids on beta-carotene uptake by Caco-, cells, Lipids.+ : 0,30-0.
93 0 Kotake-Nara, E., Yonekura, L., Nagao, A. (,*+*) E# ects of glycerophospholipid classes on b-carotene uptake by human intestinal Caco-cells, Biosci. Biotechnol. Biochem. 1. :,*3,++. 1 Asai, A., Yonekura, L., Nagao, A. (,**2) Low bioavailability of dietary epoxyxanthophylls in humans, Br. J. Nutr. +** :,1-,11. 2 Asai, A., Terasaki, M., Nagao, A. (,**.) An epoxide-furanoid rearrangement of spinach neoxanthin occurs in the gastrointestinal tract of mice and in vitro : formation and cytostatic activity of neochrome stereoisomers, J. Nutr. +-. :,,-1,,.-. 3 Baskaran, V., Sugawara, T., Nagao, A. (,**-) Phospholipids a# ect the intestinal absorption of carotenoids in mice, Lipids -2 : 1*/ 1++. +* Asai, A., Sugawara, T., Ono, H., Nagao, A. (,**.) Biotransformation of fucoxanthinol into amarouciaxanthin A in mice and HepG, cells : formation and cytotoxicity of fucoxanthin metabolites, Drug Metab. Dispos. -, :,*/,++. ++ Nagao, A., Olson, J.A. ( +33. ) Enzymatic formation of 3 -cis, +--cis, and all-trans retinals from isomers of beta-carotene, Faseb J. 2 : 30231-. +, Nagao, A., During, A., Hoshino, C., Terao, J., Olson, J.A. ( +330) Stoichiometric conversion of all trans-beta-carotene to retinal by pig intestinal extract, Arch. Biochem. Biophys. -,2 : /10-. +- During, A., Nagao, A., Hoshino, C., Terao, J. ( +330) Assay of beta-carotene +/, +/ -dioxygenase activity by reverse-phase high-pressure liquid chromatography, Anal. Biochem.,.+ : +33,*/. +. Kiefer, C., Hessel, S., Lampert, J.M., Vogt, K., Lederer, M.O., Breithaupt, D. E., von Lintig, J. (,**+) Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A, J. Biol. Chem.,10 : +.++* +.++0. +/ Asai, A., Nakano, T., Takahashi, M., Nagao, A. (,**/) Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice, J. Agric. Food. Chem. /- : 1-*, 1-*0.