Database Center for Life Science Online Service Enzyme Research, The University of Tokushima, Kuramoto-cho, Tokushima 770, Japan] Clathrin : Its Struc
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1 Enzyme Research, The University of Tokushima, Kuramoto-cho, Tokushima 770, Japan] Clathrin : Its Structure and Role in Intracellular Transport
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9 3) c ã T : Œ» 㻚w, J Š 10, (1987) 4 zpfeffer, R., Rothman, J. E.: Ann. Rev. Bio chem.,56, (1987) Drickamer, K., Parham, P.: Nature, 326, 154- Brosius, J.: Science, 236, (1987) 18 zbrodsky, F. M.: Science, 242, (1988) 19) Keen, J. H.: in Endocytosis (eds. Pastan, I., 2) Dautry-Varsat, A., Lodish, H. F.: Sci. Am., 250, (1984) 5) Orci, L., Ravazzola, M., Amherdt, M., Perre let,a., Powell, S. K., Quinn, D. L., Moore, H. -P. H.: Cell, 51, (1987) 6) Griffiths, G., Hoflack, B., Simons, K., Mell man,i., Kornfeld, S.: Cell, 52, (1988) 7) Pearse, B. M. F.: J. Mol. Biol., 97, (1975) 8) Roth, T. F., Porter, K R.: J. Cell Biol., 20, (1964) 9) Kanaseki, T., Kadota, K.: J. Cell Biol., 42, (1969) 10) Pearse, B. M. F.: EMBO J., 6, (1987) 11) Keen, J. H., Willingham, M. C., Pastan, I. H.: Cell, 16, (1979) 12) Patzer, E. J., Schlossman, D. M., Rothman, J. E.: J. Cell Biol., 93, (1982) 13) Pauloin, A., Bernier, I., Jolles, P.: Nature, 298, (1982) 14 zpfeffer, S. R., Drubin, D. G., Kelly, R. B.: J. Cell Biol., 97, (1983) 15) Kirchhausen, T., Harrison, S. C., Chow, E. P., Mattaliano, R. J., Ramachandran, K. L., Smart, J., Brosius, J.: Proc. Natl. Acad. Sci. USA, 84, (1987) 16) Jackson, A. P., Seow, H. -F., Holmes, N., 159 (1987) 17) Kirchhausen, T., Scarmato, P., Harrison, S. C., Monroe, J. J., Chow, E. P., Mattaliano, R. J., Ramachandran, K. L., Smart, J. E., Ahn, A. H., Willingham, M. C.), pp , Plenum Press, New York (1985) 20 zpearse, B. M. F., Crowther, R. A.: Ann. Rev. Biophys. Biophys. Chem., 16, (1987) 21) àšö œ{ : E Ì ª å Æ zžû ( c ã E àšö Ò), pp , u kžð, Œ ž (1983) 22) Ungewickell, E., Branton, D.: Nature, 289, (1981) 23) Kirchhausen, T., Harrison, S. C.: Cell, 23, 1823
10 (1981) 24) Crowther, R. A., Pearse, B. M. F.: J. Cell Biol., 91, (1981) 25) Kirchhausen, T., Harrison, S. C.: J. Cell Biol., 99, (1984) 26) Kirchhausen, T., Harrison, S. C., Heuser, J.: J. Ultrastruct. Mol. Struct. Res., 94, (1986) 27) Kirchhausen, T., Harrison, S. C., Parham, P., Brodsky, F. M.: Proc. Natl. Acad. Sci. USA, 80, (1983) 28) Ungewickell, E.: EMBO J., 2, (1983) 29) Winkler, F. K., Stanley, K. K.: EMBO J., 2, (1983) 30) Yoshimura, T., Kameyama, K., Maezawa, S., Takagi, T.: Š e 31) Pretorius, H. T., Nandi, P. K., Lippoldt, R. E., Johnson, M. L., Keen, J. H., Pastan, I., Edel hoch,h.: Biochemistry, 20, (1981) 32) Steer, C. J., Klauser, R. D., Blumenthal, R.: J. Biol. Chem., 257, (1982) 33) Pearse, B. M. F.: Proc. Natl. Acad. Sci. USA, 73, (1976) 34) Blank, G. S., Brodsky, F. M.: J. Cell Biol., 105, (1987) 35) Lisanti, M. P., Shapiro, L. S., Moskowitz, N., Hua, E. L., Puszkin, S., Schook, W.: Eur. J. Biochem., 125, (1982) 36) Brodsky, F. M., Parham, P.: J. Mol. Biol., 167, (1983) 37) Lemmon, S. K., Lemmon, V. P., Jones, E. W.: J. Cell. Biochem., 36, (1988) 38 zjackson, A. P., Parham, P.: J. Biol. Chem., 263, (1988) 39) Hill, B. L., Drickamer, K., Brodsky, F. M., Parham, P.: J. Biol. Chem., 263, (1988) 40) Parham, P., Brodsky, F M., Drickamer, K.: Biochem. J., 257, (1989) 41) Brodsky, F. M., Galloway, C. J., Blank, G. S., Jackson, A. P., Seow, H.-F., Drickamer, K., Parham, P.: Nature, 326, (1987) 42) Mooibroek, M. J., Michiel, D. F., Wang, J. H.: J. Biol. Chem., 262, (1987) 43) Schmid, S. L., Braell, W. A., Schlossman, D. M., Rothman, J. E.: Nature, 311, (1984) 44) Pauloin, A., Jolles, P.: Nature, 311, (1984) 45) Woodward, M. P., Roth, T. F.: Proc.. Natl. Acad. Sci. USA, 75, (1978) 46) Blitz, A. L., Fine, R. E., Toselli, P. A.: J. Cell Biol., 75, (1977) 47) van Jaarsveld, P. P., Nandi, P. K., Lippoldt, R. E., Saroff, H., Edelhoch, H.: Biochemistry, 20, (1981) 48) Nandi, P. K., van Jaarsveld, P. P., Lippoldt, R. E., Edelhoch, H.: Biochemistry, 20, (1981) 49) Vigers, G. P. A., Crowther, R. A., Pearse, B. M. F.: EMBO J., 5, (1986) 50) Nandi, P. K., Pretorius, H. T., Lippoldt, R. E., Johnson, M. L., Edelhoch, H.: Biochemistry, 19, (1980) 51) Zaremba, S., Keen, J. H.: J. Cell Biol., 97, (1983) 52) Schmid, S. L., Matsumoto, A. K., Rothman, J. K.: Proc. Natl. Acad. Sci. USA, 79, (1982) 53) Pearse, B. M. F., Robinson, M. S.: EMBO J., 3, (1984) 54 zpearse, B. M. F.: EMBO J., 7, (1988) 55) Keen, J. H,.: J. Cell Biol., 105, (1987) 56 zahle, S., Mann, A., Eichelsbacher, U., Unge wickell,e.: EMBO J., 7, (1988) 57) Robinson, M. S.: J. Cell Biol., 104, (1987) 58) Manfredi, J. J., Bazari, W. L.: J. Biol. Chem., 262, (1987) 59) Virshup, D. M., Bennett, V.: J. Cell Biol., 106, (1988) 60) Robinson, M. S.: J. Cell Biol., 108, (1989) 61) Campbell, C., Squicciarini, J., Shia, M., Pilch, P. F., Fine, R. E.: Biochemistry, 23, (1984) 62) Keen, J. H., Chestnut, M. H., Beck, K. A.: J. Biol. Chem., 262, (1987) 63) Vigers, G. P. A., Crowther, R. A., Pearse, B. M. F.: EMBO J., 5, (1986) 64) Ahle, S., Ungewickell, E.: EMBO J., 5, (1986) 65) Prasad, K., Lippoldt, R. E.: Biochemistry, 27, (1988) 66) Schlossman, D. M., Schmid, S. L., Braell, W. A., Rothman, J. E.: J. Cell Biol., 99, (1984) 67) Schmid, S. L., Rothman, J. E.: J. Biol. Chem., 260, (1985) 68 zrothman, J. E., Schmid, S. L.: Cell, 46, 5-9 (1986) 69) Ungewickell, E.: EMBO J., 4, (1985) 70) Chappell, T. G., Welch, W. J., Schlossman, D. M., Palter, K. B., Schlesinger, M. J., Rothman, J. E.: Cell, 45, 3-13 (1986) 71) Deshaies, R. J., Koch, B. D., Werner-Washburne,. M., Craig, E. A., Schekman, R.: Na ture,322, (1988) 72) Chirico, W. J., Waters, G., Blobel, G.: Nature, 332, (1988) 73) Pelham, H.: Nature, 322, (1988) 1824
11 74) Unanue, E. R., Ungewickell, E., Branton, D.: Cell, 26, (1981) 75) Prasad, D., Lippoldt, R. E., Edelhoch, H.: Bio chemistry,24, (1985) 76) Nandi, P. K., Prasad, K., Lippoldt, R. E., Alf sen,a., Edelhoch, H.: Biochemistry, 21, (1982) 77) Hanspal, M., Luna, E., Branton, D.: J. Biol. Chem., 259, (1984) 78) Moore, M. S., Mahaffey, D. T., Brodsky, F. M., Anderson, R. G. W.: Science, 236, (1987) 79) Blumenthal, R., Henkart, M., Steer, C. J.: J. Biol. Chem., 258, (1983) 80) Hong, K., Yoshimura, T., Papahadjopoulos, D.: FEBS Lett., 191, (1985) 81 zmaezawa, S., Yoshimura, T., Hong, K., Duzgu nes,n., Papahadjopoulos, D.: Biochemistry, 28, (1989) 82) Yoshimura, T., Maezawa, S., Hong, K.: J. Biochem. (Tokyo), 101, (1987) 83) Maezawa, S., Yoshimura, T.: Biochemistry, ˆó ü (1989) 84) Alstiel, L., Branton, D.: Cell, 32, (1983) 85) Heuser, J.: J. Cell Biol., 108, (1989) 8 6) Privat, J.-P., Egret-Charlier, M., Labbe, H., Ptak, M.: Biochim. Biophys. Acta, 979, (1989) 87) Griffiths, G., Simons, K.: Science, 234, (1986) 8 8) Anderson, R G W., Goldstein, J. L., Brown, M. S.: Nature, 270, (1977) 89) Lehrman, M. A., Goldstein, J. L., Brown, M. S., Russell, D. W., Schneider, W. J.: Cell, 41, (1985) 90) Davis, C. G., van Driel, I. R., Russell, D. W., Brown, M. S., Goldstein, J. L.: J. Biol. Chem., 262, (1987) 91) Lazarovits, J., Roth, M.: Cell, 53, (1988) 92) Glickman, J. N., Conibear, E., Pearse, B. M. F.: EMBO J., 8, (1989) 93) Kinnon, C., Owen, M. J.: J. Biol. Chem., 258, (1983) 94) Strous, G. J. A. M., Willemsen, R., van Kerk hof,p., Slot, J. W., Geuze, H. J., Lodish, H. F.: J. Cell Biol., 97, (1983) 95) Griffiths, G., Pfeiffer, S., Simons, K., Matlin, K.: J. Cell Biol., 101, (1985) 96) Orci, L., Glick, B. S., Rothman, J. E.: Cell, 46, (1986) 97) Payne, G. S., Schekman, R.: Science, 230, (1985) 98 zpayne, G. S., Baker, D., van Tuinen, E., Schek man,r.: J. Cell Biol., 106, (1988) 99) Lemmon, S. K., Jones, E. W.: Science, 238, (1987) 100) Takahashi, A., Usami, M., Kadota, T. Kadota, K.: J. Biochem. (Tokyo), 98, (1985) 101) Bar-Zvi, D., Branton, D.: J. Biol. Chem., 261, (1986) 102) Usami, M., Takahashi, A., Kadota, T., Kado ta,k.: J. Biochem. (Tokyo), 97, (1985) 103) Schook, W. J., Puszkin, S.: Proc. Natl. Acad. Sci. USA,. 82, (1985) 104) Keen, J. H., Black, M. M.: J. Cell Biol., 102, (1986) 105) Goud, B., Huet, C., Louvard, D.: J. Cell Biol., 100, (1985) 106 zbar-zvi, D., Mosley, S. T., Branton, D.: J. Biol. Chem., 263, (1988) 107) Pauloin, A., Jolles, P.: J. Biol. Chem., 261, (1986) 108) Pauloin, A., Thurieau, C., Jolles, P.: Biochim. Biophys. Acta, 968, (1988) 109) Arai, H., Terres, G., Pink, S., Forgac, M.: J. Biol. Chem., 263, (1988) 110) å ¼ rˆê :»Šw, 60, (1988) 1825
Minamiooya, Machida, Tokyo 194, Japan] RNA World, A Key Step in the Origin of Life : Inspection from the View Point of Biological Evolution 1) Crick, F. H. C.: Sym. Soc. Exp. Biol., 12, 548-555
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Spatio-temporal regulation of ERK1/2 MAP kinase 20) Murphy, L. 0., MacKeigan, J. P., Blenis, J.: Mol. Cell. Biol., 24, 144-153 (2004) 21) Harada, T., Morooka, T., Ogawa, S., Nishida, E.: Nature Cell
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Database Center for Life Science Online Service
1) Epps, H. M., Gale, E. F.: Biochem. J., 36, 619-623 (1942) 2) Monod, J.: Recherches sur la croissance des cultures bacteriennes, Ph. D. thesis. Her mann,paris (1942) 3) Magasanik, B.: Cold Spring Harbor
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1) van Meer, G., Op den Kamp, J. A.: J. Cell. Biochem., 19, 193-2040982) 2) Gaffet, P., Bettache, N., Bienvenue, A.: Biochemistry, 34, 6762-6769(1995) 3) Sims, P. J., Wiedmer, T.: Thromb. Haemost., 86,
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1) Dalton, A. J. et al. : J. Nat. Cancer Inst., 11 : 439, 1950. 2) Fawcett, D. W.: J. Nat. Cancer Inst., 15 :1475, 1955. 3) Oberling, C. et Rouiller, C.: Ann. d'anat. path., 1: 401, 1956. 4) Palade, G.
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2) Shin, S. I., Fredman, V. H., Risser, P., Pol lack,r.: Proc. Natl. Acad. Sci. USA, 72, 4435-4439 (1975) 3) Marquardt, H., Todaro, G. J.: J. Biol. Chem., 256, 6859-6865 (1981) 4) Dicker, P., Pohjanpelto,
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Database Center for Life Science Online Service
1) Bittner, J. J.: Science, 84, 162 (1936) 13) Michalides, R., van Ooyen, A., Nusse, R.: Curr. Top. Microbiol. Immunol., 106, 57-74 (1983) 2 z Yamamoto, K. R.: Ann. Rev. Genn., 19, 209-252 (1985) 3) Evans,
1) Ogawa, H., Lazarus, G. S., Hopsu-Havu, K.: The Biological Role of Proteinases and their Inhibitors in Skin, Univ. Tokyo Press (1985) 2) Sottrup-Jensen, L., Stepanik, T. M., Kristen sen,t., Wierzbicki,
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Database Center for Life Science Online Service Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie
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Teru Ogura, Tomoko Yamada-Inagawa, E-mail : ogura@gpo.kumamotou.ac.jp AAA family ATPases : ring-shaped chaperones which catalyze energy-dependent conformational changes of proteins 29) Braun, S.,
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Review Fumio Imamoto1, Takefumi Sone1, Kazuhide Yahata1, Yukari Sasaki1, Masatoshi Takagi2, Kazuhiro Maeshima2, Naoko 25) Dong, W. K. et al.: Gene, 91, 217-223 (1990) 26) Masatsugu, T. et al.:
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drug development Toshimi Michigami, E-mail : michigami@mch.pref.osaka.jp Keiichi Ozono, E-mail : keioz@ped.med.osaka-u.ac.jp The progress in the research on vitamin D 1) McCollum, E. V. et al.:
Review Database Center for Life Science Online Service Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge
Review Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge E-mail : m.mishima @gurdon.cam.ac.uk http://www.gurdon.cam.ac.uk/groups/mishima.html Cytokinesis :
64) M.L. Gefter, R.L. Russell: J. Mol. Biol., 39, 145 (1969) 65) F. Harada, F. Kimura and S. Nishimura: Biochim. Biophys. Acta., 182, 590 (1969) 65a) F.H.C. Crick: J. Mol, Biol., 19, 548 (1966); M. Nirenberg
2007 Vol.56 No.6 総説 丸山浩樹
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Stress-responsive MAP kinases 15) Lu, H. T., Yang, D. D., Wysk, M., Gatti, E., Mellman, I., Davis, R. J., Flavell, R. A. : EMBO J., 18,1845-1857 (1999) 16) Lu, B., Yu, H., Chow, C., Li, B., Zheng,
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Short Review Hidenori Takagi, Fumio Takaiwa, E-mail : takaiwa@nias.affrc.go.jp 13) Hirahara, K. et al. : J. Allergy Clin. Immunol., 102, 961-967 (1998) 14) Takagi, H. et al.: Proc. Natl. Acad. Sci.