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1 Proceeding 1. Cushing Year note (2005) MEDIC MEDIA 2. Functional genomics (2005) (2005) 4. HT(Hypertension ) (2005) (2005) (2005) 7... MRI,MRS (2005) 8. (MEDC ) Vol (2005) SANKEISHA

2 1. Morita H., Hirota T., Mune T., Suwa T., Ishizuka T., Inuzuka T., Tanaka K., Ishimori M., Nakamura S., Yasuda K Paraneoplastic neurologic syndrome and autoimmune Addison disease in a patient with thymoma. Amer. J. Med. Sci. 329(1) : (2005) 2. Kawachi S., Takeda N., Sasaki A., Kokubo Y., Takami K., Sarui H., Hayashi M., Yamakita N., Yasuda K. Circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 are associated with early carotid atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 25(3): (2005) 3. Isaji M., Mune T., Takada N., Yamamoto Y., Suwa T., Morita H., Takeda J., White P.C. Correlation between left ventricular mass and urinary sodium excretion in specific genotypes of CYP11B2. J. Hypertens. 23(6): (2005) 4. WangH., Horikawa Y., Jin L., Narita T., Yamada S., Shiahara N.,Takemoto K., Muramatu M., Mune T., Takeda J Gene expression profile in rat pancreatic islet and RINm5F cells. J. Mol. Endocrinol. 35 : 1-12 (2005) 5. Tanahashi H., Mune T., Takahashi Y., Isaji M., Suwa T., Morita H., Yamakita N., Yasuda K.,Deguchi T., White P.C., Takeda J. Association of Lys173Arg polymorphism with CYP11B2 expression in normal adrenal glands and aldosterone-producing adenomas. J. Clin. Endocrinol. Metab. 90(11): (2005) 6. Yamada N., Horikawa Y., Oda N., Iizuka K., Shihara N., Kishi S, Takeda J. Genetic variation in the hypoxia-inducuble factor 1 gene is associated with type 2 diabetes in Japanese J. Clin. Endocrinol. Metab. 90(10) : (2005) 7. Ueno H., Yamada Y., Watanabe R., Mukai E., Hosokawa M., Takahashi A., Hamasaki A., Fujiwara H., Toyokuni S., Yamaguchi M., Takeda J., Seino Y. Nestin-positive cells in adult pancreass express amylase and endocrine precursor cells. Pancreas 31: (2005)

3 8. Iwasaki N., Horikawa Y., Tsuchiya T., Kitamura Y., Nakamura T., Tanizawa Y., Oka Y., Hara K., Kadowaki T., Awata T. Honda M., Yamashita K., Oda N., Yu L., Yamada N., Ogata M., Kamatani N., Iwamoto Y., Del Bosque-Plata L., Hayes MG., Cox NJ., Bel GI. Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population. J. Hum. Genet. 50:92-98 (2005) 9. Nakano Y., Furuta H., Doi A., Matsuno S., Nakagawa T., Shimomura H., Sakagashira S., Horikawa Y., Hishi M., Sasaki H., Sanke T., Nanjo K. A functional variant in the human betacellulin gene promoter is associated with type 2 diabetes. Diabetes 54: (2005) CT 19 : (2005) : (2005) : (2005) 13. CAMPUS HEALTH 42 : 148(2005) 14. CAMPUS HEALTH 42 : 183(2005)

4 15. CAMPUS HEALTH 42 : 193(2005) 16. CAMPUS HEALTH 42 : 204(2005) NGFIB (2005)

5 1. 6 (2005) ( 3): (2005) 3. Apparent Mineralocorticoid Excess (AME) 63( 3): (2005) 4. :15 (2005) (5): (2005) 6. 12(7): (2005) 7. 54(7) : (205) HSD2 AME 21(3): (2005) 9. Funder JW. Medical Tribune 38(42):60-61 (2005) 10. / Arterial Stiffness 7:54-55 (2005) 11. Arterial Stiffness 8:32-33 (2005)

6 12. A sign of atherosclerosis. ASO (MRA) Medical Tribune 38(34):39 (2005) 13. CRP Diabetes Frontier 16(6): (2005) 14. TOPICS VIEW WellVAS 13:8-11 (2005) : (2005) (2005) (2005) 18. 5: (2005) 19. Sophia Life Science Bulletin 24:3-8 (2005) MBA Japan Medicine

7 1. 2. Update Hai Yan Graeme Bell Calpain A-2T 6. Graeme Bell CAPN Kosaku Uyeda ChREBP ChREBP knockout mouse MR 10. / Dehydroepiandrosterone(DHEA)

8 12. BMI MR Moro H SatoH Ida I Oshima A Sakurai N Shihara N Horikawa Y MikuniM Effects of SKF-38393, a selective dopamine D1 receptor agonist on expression of d-amphetamine induced behavior and expression of the immediate early gene Arc in the prefrontal cortex of rats UPI GHQ Disabled-2

9 ASVS,CTA 2. Schwanoma QOL 7. PTSD

10 SHP Polyglandular autoimmune type MODY 21.

11 31 st International Aldosterone Conference San Diego June Muramatu M., Suwa T., Mune T., Takeda J. Specific expression of disabled-2 in zona glomerulosa and its upregulation by low sodium diet. The Endocrine Society s 87 th Annual Meeting San Diego June Mune T., Muramatu M., Suwa T., Takeda J. NR4A Family and steroidogenic enzymes in adrenocortical tumors. 3. Suwa T., Muramatu M., Mune T., Takeda J. In situ detection of genes regulated by ACTH in rat adrenal. 4. Muramatu M., Suwa T., Mune T., Takeda J. In situ detection of genes regulated by low-sodium diet in rat adrenal. 5. Yamamoto M., Kubota Y., Nagase E., Mochizuki A. Ohba S., Suzuki E., Takeda J Community-based diabetes prevention program for pre-diabetes patients in Gifu Japan. 65 th American Diabetes Association Annual Meeting and Scientific Sessions San Diego June Kajita K., Mune T., Matsumoto M., Sugiyama C., Uno Y., Morita H., Ishizuka T. Effect of the peroxisome proliferators-activated receptor (PPAR ) and activated kinase (AMPK) activity in adipocytes. 7. Ishizuka T., Matsumoto M., Kajita K., Suguyama C., Morita H., Uno Y., Ikeda T., Matsubara K., Mune T., Takeda N., Yasuda K. Dehydroepiandrosterone-induced improvement of insulin resistance in rat adipocytes ant its clinical significance in male adults 8. Suzuki E., Yoshimura T., Tsuchiya M., Egawa K., Nishio Y., Maegawa H., Kashiwagi A. Glycemic control is only an independent risk factor for progression of stiffness and impaired circulation in lower-leg arteries of patients with type 2 diabetes mellitus. 9. Yoshimura T., Suzuki E., Egawa K., Nishio Y., Maegawa H., Hisatomi A., Kashiwagi A. MR angiography of lower extremities predicts cardiovascular events in diabetic patients. 10. Yamamoto M.,Unemoto T., Suwa T., Sasaka A., Kinosada Y., Takeda J. The new e-smbg system in Gifu University Hospital uniting data for all typer of SMBG machines.

12 Fifth Annual Diabetes Technology Meeting, Diabetes Technology Society San Francisco Yamamoto M., Takeda J., Kinosada Y. System for standardizing and analyzinh SMBG (Self monitoring of blood glucose ) data from various machines in patient s electric medicalrecord system. Society for Neuroscience 35 th Annual Meeting Washington Nov Moro H Sato H Ida I Oshoma A Sakurai N Shihara N Horikawa Y Mikuni M Effects of SKF-38393, a selective dopamine D1receptor agonist on expression of d-amphetamine induced behavior an expression of the immediate early gene Arc in the prefrontal cortex of rats

13 1. NGFIB Final report of practical Thiazolidine 5. Dehydroepiandrosterone(DHEA) TNF,starvation Bio

14 Disabled-2

15 Final report of practical Thiazolidine 7. TQM 8. LRH

16 12. SU QOL

17 DMC DM

18

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