Juntendo Medical Journal

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1 Recent progress in nephrology Key words: rapid high elf icency dialysis, phosphate transport, plasma membrane Na+ transport, cytokine, extracellular matrix

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11 5) Nagasawa M, Koide H, Ohsawa K, Hoshi T : Purification of brush border membrane vesicles from rat renal cortex by size-exclusion chromatography. Anal Biochem., 201 : 301~305, ) Hirano K, Nagasawa M, Kubota M, Tomino Y, Koide H : Effects of acute and chronic parathyroidectomy on phosphate transport in brush border membrane vesicles. J Bone Mineral Metab., 7 : 161~167, ) Koide H, Nagasawa M : Phosphote transport by renal brush border membrane. Couple Transport in Nephron. Mechanisms and Pathophysiology. 3 0~3 8, Miura Medical Research Foundation, Tokyo, ) Saito K, Hirano K, Kubota M, Tomino Y,

12 Koide H : Effect of parathyroid-hormone-related protein on sodium-dependent phosphate transport in renal brush border membrane vesicles in rats. Nephron, 64: 600~604, ) Yokomatsu M, Fujito K, Numahata H, Koide H : Erythrocyte sodium ion transport system in DOC-salt, Goldblatt, and spontaneously hypertensive rats. Scand J Clin Lab Invest, 52 : 497~ 506, ) Fujito K, Yokomatsu M, Numahata H, Ishiguro N, Koide H : Acute effects of angiotensinconverting enzyme inhibitor on erythrocyte sodium ion transport in essential hypertension. Life Sci., 51: 2079~2087, ) Fujito K, Yokomatsu M, Ishiguro N, Numahata H, Tomino Y, Koide H : Effect of dietary Ca2+ on erythrocyte Na+ -transport systems in spontaneously hypertensive rats. Clin Sci., 81 : 107~112, ) Nakamura T, Ebihara I, Fukui M, Takahashi T, Tomino Y, Koide H : Altered glomerular mrna during nephrotic and sclerotic phases of puromycin aminonucleoside nephrosis in rats. Clin Sci., 84 : 349~356, ) Tomino Y, Funabiki K, Ohmuro H, Shimizu M, Yokoyama K, Shirato I, Takahashi M, Koide H : Urinary levels of interleukin- 6 and disease activity in patients with IgA nephropathy. Am J Nephrol., 11 : 459~464, ) Nakamura T, Ebihara I, Takahashi T, Yamamoto M, Tomino Y, Koide H.: Increased interleukin 6 mrna expression by peripheral blood T cells from patients with IgA nephropathy. Autoimmunity, 15 : 171~179, ) Iida H, Seifert R, Alpers CE, Gronwald RGK, Phillips PE, Pritzl P, Gordon K, Gown AM, Ross R, Bowen-Pope DF, Johnson RJ : Plateletderived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat. Proc Natl Acad Sci USA, 88 : 6560~6564, ) Johnson RJ, Raines EW, Floege J, Yoshimura A, Pritzl P, Alpers C, Ross R : Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor. J Exp Med., 175 : 1413~1416, ) Nakamura T, Ebihara I, Nagaoka I, Tomino Y, Koide H : Renal platelet-derived growth factor gene expression in NZB /WF 1 mice with lupus and ddy mice with IgA nephropathy. Clin Immunol Immunopathol, 63 : 173~ 181, ) Floege J, Burns MW, Allpers CE, Yoshimura A, Pritzl P, Gordon K, Seifert RA, Bowen-Pope DE, Couser WG, Johnson RJ : Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model. Kidney Int., 41: 297~309, ) Nakamura T, Ebihara I, Fukui M, Osada S, Nagaoka I, Horikoshi S, Tomino Y, Koide H : Messenger RNA expression for growth factors in glomeruli from. focal glomerular sclerosis. Clin Immunol Immunopathol, 66 : 33~42, ) Fukui M, Nakamura T, Ebihara I, Nagaoka I, Tomino Y, Koide H : Low-protein diet attenuates increased gene expression of platelet-derived growth factor and transforming growth factor- Clin Med., 121 : 224~234, ) Nakamura T, Ebihara I, Nagaoka I, Tomino Y, Koide H : Activated periperal blood mononuclear cells in IgA nephropathy express plateletderived growth factor B chain messenger RNA. J Lab Clin Med., 120 : 212~221, 1992 regulation of extracellular matrix. Kidney Int., 41: 557~559, ) Border WA, Okuda S, Languino LR, Ruoslahti production of proteoglycans by mesangial cells. Kidney Int., 37: 689~695, ) Suzuki S, Ebihara I, Tomino Y, Koide H : Transcriptional activation of matrix genes by

13 cells. Exp. Nephrol., 1 : 229~237, ) Okuda S, Languino LR, Ruoslahti E, Border WA : Elevated expression of transforming growth perimental glomerulonephritis. J Clin Invest, 86 : 453~462, ) Border WA, Okuda S, Languino LR, Sporn MB, Ruoslahti E : Suppression of experimental glomerulonephritis by antiserum against trans- 374, ) Okuda S, Nakamura T, Yamamoto T, Ruoslahti E, Border WA : Dietary protein restriction 1 expression in experimental glomerulonephritis. Proc Natl. Acad Sci USA, 88: 9765~9769, ) Nakamura T, Ebihara I, Nagaoka I, Osada S, Tomino Y, Koide H Effect of methylprednisolone on transforming growth factor-beta, insulin-like growth foctor- 1 and basic fibroblast growth factor gene expression in the kidneys of NZB /WF 1 mice. Renal Physiol Biochem., 16: 105~116, ) Nakamura T, Ebihara I, Shirato I, Tomino Y, Koide H : Modulation of basement membrane component gene expression in glomeruli of aminonucleoside nephrosis. Lab Invest., 64: ) Nakamura T, Ebihara I, Fukui M, Tomino Y, Koide H : Effect of methylpredonisolone on glomerular and medullary mrna levels for extracellular matrices in puromycin aminonucleoside nephrosis. Kidney Int., 40 : 874~881, ) Nakamura T, Ebihara I, Shirato I, Tomino Y, Koide H : Increased steady-state levels of mrna coding for extracellular matrix components in kidneys of NZB /W F 1 mice. Am J Pathol., 139: 437~450, ) Nakamura T, Ebihara I, Tomino Y, Koide H : Glucocorticoid ameliorates altered gene expression of extracellular matrix components in kidneys of New Zealand Black /White F 1 mice. Clin. Sci, 83 : 701~709, ) Ebihara I, Suzuki S, Nakamura T, Fukui M, Yaguchi Y, Tomino Y, Koide H : Extracellular matrix component mrna expression in glomerulus in experimental focal glomerulosclerosis. J Am Soc Nephrol., 3 : 1387~-1397, ) Nakamura T, Fukui M, Ebihara I, Tomino Y, Koide H : Low protein diet blunts the rise in glomerular gene expression in focal glomerulosclerosis. Kidney Int., 45 : 1593~1605, ) Poulsom R, Kurkinen M, Prockop DJ : Increased steady-state levels of laminin B 1 mrna in kidneys of long-term streptozotocindiabetic rats. J Biol Chem., 263: 10072~10076, ) Fukui M, Nakamura T, Ebihara I, Shirato I, Tomino Y, Koide H : ECM gene expression and its modulation by insulin in diabetic rats. Diabetes., 41: 1520~1527, 1992

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