A ctino bacillus actinomycetemcomitans, Porphyromonas gingivalis, Fusobacterium nucleatum Influence of Complement and Antibody on Superoxide Productio
|
|
|
- こうしょ ひきぎ
- 5 years ago
- Views:
Transcription
1 A ctino bacillus actinomycetemcomitans, Porphyromonas gingivalis, Fusobacterium nucleatum Influence of Complement and Antibody on Superoxide Production, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Fusobacterium nucleatum Phagocytosis and Killing by Leukocytes Kazutaka Ogiwara*, Chihomi Kato and Kazuko Saito Department of Oral Microbiology, School of Dentistry at Niigata, The Nippon Dental University 1-8 Hamaura-cho, Niigata 951, Japan Director : Prof. Kazuko Saito) ( *Present address : Department of Periodontology, The Nippon Dental University Fujimi, Chiyoda-ku, Tokyo 102, Japan The purpose of this experiment was to clarify the influence of antibody and complement on the superoxide production [Chemiluminescence (CL) response] and periodontopathic bacteria phagocytosis and killing by polymorphonuclear leukocytes (PMNs). PMNs were obtained from the peritoneal cavity of ICR mice after caseinate injection. Three species of periodontopathic bacteria were used : Actinobacillus actinomycetemcomitans Aa), Porphyromonas gingivalis ( (Pg) and Fusobacterium nucleatum (Fn). Mice were immunized with live Aa, Pg or Fn vaccine. Serum was obtained from the blood by cutting the carotid artery. Normal serum was used as complement and inactivated immune serum was used as the antibody. The antibody titers were measured by ELISA using sonicated Aa, Pg and Fn antigen. Serum with a high antibody titer was obtained. IgG levels were high when mice were immunized with either Aa or Pg, whereas IgM levels were high when immunized with Fn. The reaction mixture for the CL response consisted of luminol solution, serum, gelatin Hanks' solution, PMNs and the bacteria. After the CL response was complete, a portion of the reaction mixture was smeared on a glass slide, dried and stained with May-Gruenwald- Giemsa stain. Phagocytic activity was assessed using a microscope. Surviving bacteria were counted on solid medium after treatment with serum, antibody and PMNs alone or in combination. An increase in the CL response to Aa occurred and was dependent on the addition of complement, and the response to Pg was dependent on both complement and antibody whereas the response to Fn dependent on neither complement nor antibody. The CL response to Fn was inhibited by D- galactose, N- acetyl-d-galactosamin and mannan. Phagocytic rate of PMN and the number of Aa and Fn bacteria in PMNs was enhanced in the presence of complement. The co-operation of both complement and antibody was needed to increase the phagocytic ratio. The bactericidal effect of complement, antibody and PMN were examined in single or combination mixtures. There was no
2 marked effect on killing the bacteria in any combination. In conclusion, complement plays the role of enhancing the CL response and phagocytic activity in response to Aa. Co-operation of complement was necesary for phagocytosis of Fn. High titer antibody, complement and PMN had no bactericidal effect under the experimental conditions. Key words : PMN, Antibody, Complement, CL response, Killing
3
4
5
6
7
8
9
10
11
12 Derangement of nonspecific immunity in Down syndrome subjects: Low leukocyte chemiluminescence activity after phagocytic activation. American Jounal of Medical Genetics Supple)., 7: , ( 12) Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. L. : Protein measurement with the 1) Attstrom, R.: Presence of leukocytes in crevices N.: Humoral immune response to oral microorganisms in periodontitis. Infect. Immun., 37: of healthy and flammed gingivae. J. Periodontal. Res., 5: , ) Holm, A. and Kalfus, S.: Polymorphonuclear leukocyte chemiluminescence induced by Actino- 3) Listgarten, M. A., Lai, C. H. and Evain, C. I.: Comparative antibody titers to Actinobacillus actinobacillus actinomycetemcomitans and Haemophilus aphrophilus in serum and saliva, Scand. J. Dent. mycetemcomitans in juvenile periodontitis, chronic Res., 101: , periodontitis, and periodontally healthy subjects. J. Clin. Periodontol., 8: 155, ) Mouton, C., Hammond, P. G., Slots, J. and Genco, R. J.: Serum antibodies to oral Bacteroides asaccharolyticus (Bacteroides gingivalis) : relationship 16) Whyte, G. J., Seymour, G. J., Cheung, K. and Robin- to age and periodontal disease. Infect. Immun., son, M. F. : Chemiluminescence of peripheral 31: , polymorphonuclear leukocytes from adults periodositis patients. J. Clin. Periodontol., 16: 67-74, 5) Tolo, K. and Brandtzaeg, P.: Relation between periodontal disease activity and serum antibody titers to oral bacteria, Genco, R. T. and Mergenhagen, S. E., Host-parasite interactions in perigan, D. F. : A non-lectin-like mechanism by which 17) Tuttle, R. S., Strubel, N. A., Mourad, J. and Manodontal disease, Amer. Soc. Microbiol., Washigton, D. C., , activates human lymphocytes. Oral. Microbiol. Fusobacterium nucleatum adheres to and 6) Schenkein, H. A.: The role of complement in Immunol., 7: 78-83, periodontal disease. Oral. Biol. Medicine., 2: 65-18) Mangan, D. F., Novak, M. J., Vora, S. A., Mourad, 81, J. and Kriger, P. S.: Lectinlike interactions of 7) Nisengard, R. and Jarrett, C.: Coating of subgin- Fusobacterium nucleatum with human neutrophils. gival bacteria with immunogloblins and complement. J. Periodontol., 47: , ) Bissada, N. F., Mancou-chehrPour, M., Haddow, M. and Spagnuole, P. J. : Neutrophil functional activity in juvenile and adult onset diabetic patients with mild and severe periodontitis. J. Periodont. Res., 17: , ) Temple, T. R., Kimball, H. R., Kakehashi, S. and Amen, C. R.: Host factors in periodontal disease: Periodontal manifeststions of Chediak- Higashi syndrome. J. Periodont. Res., 7: 26-27, ) Genco, R. J. and Slots, J.: Host response: Host responses in periodontal disease. J. Oral. Pathol., 14: , ) Licastro, F., Melotti, C., Parente, R., Davis, L. J., Chiricolo, M., Zannotti, M. and Barboni, F.: folin phenol reagent. J. Biol. Chem., 193: , ) Doty, S. L., Lopatin, D. E., Syed, S. A. and Smith, F. Infect. Immun., 57: , ) Slots, J. and Genco, R. J.: Microbial oathogenicity. Black-pigmented Bacteroides species, Capnocytophaga species, and Actinobacillus actinomycetemcomitans in human periodontal disease: Virulence factors in colonization, survival, and tissue destruction. J. Dent. Res., 63: , ) Wilson, M. E. and Genco, R. J.: The role of antibody, complement and neutrophils in host defense against Actinobacillus actinomycetemcomitans. Immunol. Invest., 18: , ) Greiner, D., Mayrand, D. and McBride, B. C.: Further studies of the degradation of immunoglobulins by black-pigmented bacteroides. Oral. Immunol., 4: 12-18, ) Cutler, C. W., Kalmar, J. R. and Arnold, R. R.:
13 Phagocytosis of virulent Porphyromonas gingivalis by human polymorphonuclear leukocytes requires specific immunoglobulin G. Infect. Immun., 59: , ) Davis, S. D. and Wedgwood, W. J.: Kinetics of the bactericidal action of nomal serum on gram-negative bacteria. J. Immunol., 95: 75-79, ) Miyasaki, K.T., Wilson, M.E., Brunetti, A. T. and Genco, R.J.: Oxidative and nonoxidative killing of Actinobacillus actinomycetemcomitans by human neutrophils. Infect. Immun., 53: , ) Holm, A., Kalfas, S. and Holm, S. E.: Killing of Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus by human polymorphonuclear leukocytes in serum and saliva. Oral. Microbiol. Immunol., 8: , ) Sandqvist, G. and Johansson, E.: Bactericidal effect of pooled human serum on Bacteroides melaninogenicus, Bacteroides asaccharolyticus and Actinobacillus actinomycetemcomitans. Scand. J. Dent. Res., 90: 29-36, ) Okuda, K., Kato T., Naito, Y., Ono, M. and Takazoe, I.: Suscertibility of Bacteroides gingi- 30) Evans, R. T., Spaeth, S., Mergenhagen, S. E.: Bactericidal antibody in mammalin serum to obligatory anaerobic Gram-negative bacteria. J. Immunol., 97: , ) Clark, R. A., Leidal, K. G. and Taichman, N. S.: Oxidative inactivation of Actinobacillus actinornycetemenmitans and Haeynophilus aphrophilus to oxidative killing. Infect. Immun., 53: , valis to bactericidal activity of human serum. J. phils lack defensins. Infect. Immun., 60: Dent. Res., 65: , , ) Sandqvist, G. K., Carlsson, J., Herrmann, B.F. and 36) Amano, A., Tamagawa, M., Takagaki, M., Murakami, Y. and Tsunemitsu, A.: Relationship Tarnvik, A.: Degradation of human immunogloblins G and M and complement factors C 3 and C 5 between enzyme activities involved in oxygen by black-pigmented Bacteroides. J. Med. Microbiol., 19: 85-94, mented Bacteroides. J. Dent. Res., 67: , metabolism and oxygen tolerans ib black-pig ) Kalmar, J. R., Arnold, R. R. and van Dyke, T.E.: Direct interaction of Actinobacillus actinomycetemcomitans with nomal and defective (LJP) neutrophils. J. Periodont. Res., 22: , ) Slots, J.: Salient biochemical characters of Actinobacillus actinomycetemcomitans. Archs. Microbiol., 131: 60-67, ) Miyasaki, K. T., Wilson, M. E., Reynolds, H. S. and Genco, R. J.: Resistance Actinobacillus actinomycetemcomitans and differential susceptibility of the oral haemophili to the bactericidal effects of hydrogen peroxide. Infect. Immun., 46: , ) Eisenhauer, P. B. and Lehrer, R. I.: Mouse neutro-
To establish a local therapy of periodontitis by using minocycline HCl, a series of studies has been conducted. The present study was to re-confirm th
Local Administration of Minocycline for Periodontitis Double Blind Comparative Study of LS-007 Yoji MURAYAMA1), Yoshio NOMURA1), Akira YAMAOKA2), Masatoshi UEDA2), Toshio HORP), Masato MINABE3), Toshio
Key words : Adverse reactions, Egg allergy, IgG antibody, Mills allergy, FAST
Key words : Adverse reactions, Egg allergy, IgG antibody, Mills allergy, FAST 13) Danaeus, A., Johansson, S. G. O., Foucard, T. & Ohman, S.: Clinical and immunogical aspects of food allergy in childhood.
Table 1 Survival rates of infected mice given antibiotic doses producing peak serum a) S. aurcus Smith Challenge dose :7 ~10 (5% mucin) CFU/mouse. LD50: 1 ~103 (5% mucin) CFU/mouse. Table 2 Survival rates
Microflora in Patients Treated with Fixed Prosthetic Appliances Supragingival Plaque Formed on the Full Cast Crown - Fabricated with Platinum Gold Cas
Microflora in Patients Treated with Fixed Prosthetic Appliances Supragingival Plaque Formed on the Full Cast Crown - Fabricated with Platinum Gold Cast Alloy- Junichi Mega, Yosizumi Murata, Masatomo Hirasawa*
Fas and Ley antigen expression in polymorphonuclear leukocytes. Satoshi Nishizawa, Yukihiro Numabe and Kyuichi Kamoi Department of Periodontology, School of Dentistry at Tokyo, The Nippon Dental University
semen quality or those without WBC in semen. In the patients with azoospermia and normal FSH levels (normogonadotropic azzospermia), the antibody (IgG
CLINICAL STUDIES OF UROGENITAL INFECTIONS WITH CHLAMYDIA TRACHOMA TIS Report 2. The Epidemiology of Chlamydial Infections in Okayama District in Japan and Detection of Antibodies to Chlamydiae in the Sera
The positive correlation between bad breath and subgigival microflora OTakafumi Department of Periodontics, Tokyo Dental College MORIYAMA, Masatake TS
A study of ultrasonic scaling with regard to the changes of bacterial phase in the periodontal pocket Department of Periodontology, *Preventive Dentistry, **Bacteriology, Osaka Dental University Masatoshi
VOL.32 S-9 CHEMOTHERAPY Table 1 Minimum inhibitory concentrations of AC-1370, CPZ and CAZ Table 2 Efficacy of AC-1370 and CPZ against systemic infections in mice *Inoculum size: 106 cells/ml * 95% confidence
Modulation of T-cell Subsets by Bacteroides gingivalis Department of Periodontics & Endodontics, Faculty of Dentistry, Kyushu University Yuji KITAMURA
Lymphocyte Subsets in mice treated with the fimbriae from Porphyromonas gingivalis Division of Animal Experimentation, Sapporo Medical College,*Department of Preventive Dentistry, Higashi Nippon Gakuen
AUTONOMIC FUNCTIONAL STATE IN RENAL TUBERCULOSIS REPORT III. SERUM CHOLINESTERASE ACTIVITY IN RENAL TUBERCULOSIS Sanai Yamamura The Department of Urol
AUTONOMIC FUNCTIONAL STATE IN RENAL TUBERCULOSIS REPORT III. SERUM CHOLINESTERASE ACTIVITY IN RENAL TUBERCULOSIS Sanai Yamamura The Department of Urology, Kumamoto University College of Medicine (Director:
Clostridium difficile ciprofloxacin, ofloxacin, norfloxacin Bifidobacterium Lactobacillus Lactobacillus Bacteroides fragilis B. fragilis C. difficile
Clostridium difficile ciprofloxacin, ofloxacin, norfloxacin Bifidobacterium Lactobacillus Lactobacillus Bacteroides fragilis B. fragilis C. difficile Key words: temafloxacin, TA-167, Bacteroides fragilis,
日本消化器外科学会雑誌第29巻第9号
Table 1 Oligonucleotide primers used for RT-PCR and internal probes used for Southern blot hybridization Cytokine Primer Sequence (5'-3') 5' 3' Internal probe s' 3' Internal probe 5' 3' Internal probe
CHEMOTHERAPY APR Fig. 2 The inactivation of aminoglycoside antibiotics by PC-904 Fig. 3 Serum concentration of PC-904 (1) Fig. 4 Urinary recover
VOL.26 S-2 CHEMOTHERAPY Gentamicin (GM), Dibekacin (DKB), Tobramycin Fig. 1 Protein concentration and protein binding rate Table 2 Protein binding rate of PC-904 in serum of healthy adults, and patients
CHEMOTHERAPY JUNE 1993 Table 1. Background of patients in pharmacokinetic study
CHEMOTHERAPY JUNE 1993 Table 1. Background of patients in pharmacokinetic study VOL. 41 S 1 Table 2. Levels (Đg/ml or Đg/g) of S-1006 in serum, bile, and tissue (gallbladder) after oral administration
*...C
J Health Care Dent. 2004; 6: 23-41 Printed in Japan. All rights reserved * Reconsideration of Diagnosis, Treatment and Maintenance of Periodontal Disease Periodontitis is different from other infectious
Studies on the Antigens Expressed on Trophoblasts Related to MLR-blocking Antibodies Shigenori GOTO Department of Obstetrics and Gynecology, Niigata University School of Medicine (Director: Prof. Shoshichi
The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursi
The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursing Professionals for Diabetic Outpatients Not Using
Fig. 1 Chemical structure of DL-8280
Fig. 1 Chemical structure of DL-8280 Fig. 2 Susceptibility of cl in ical isolates to DL4280 Fig. 5 Susceptibility of clinical isolates to DL-8280 Fig. 3 Susceptibility of clinical isolates to DL-8280 Fig.
1) Topley & Wilsons: Principles of Bacterio- 583-591.-5) Huddleson, I.F.: Brucellosis in man and animals, 1943. -6) Wilson, G. S. & encountered in certain Br. abortus agglutinating sera, J. Path. & Bact.,
ESTIMATION OF THE SALIVARY ANTIBACTERIAL ACTIVITY IN TRYPTICASE SOY AGAR BY CUP PLATE METHOD BY Hajime TAKAHATA, Toshio MORIOKA and Toshiharu MATSUMURA The peroxidase antibacterial action in human saliva
untitled
11-19 2012 1 2 3 30 2 Key words acupuncture insulated needle cervical sympathetick trunk thermography blood flow of the nasal skin Received September 12, 2011; Accepted November 1, 2011 I 1 2 1954 3 564-0034
VOL.30 NO.10 CHEMOTHERAPY 1123 Fig,1 Group B case 6 hepatolithiasis,e.k.66 y.0.,f.45kg Postoperative wound infection Fig.2 Group B case 15 gastric cancer,k.k.60 y.o.,m. Postoperative peritonitis Fig.3
CHEMOTHERAPY Fig. 1 Chemical structure of TE-031
CHEMOTHERAPY Fig. 1 Chemical structure of TE-031 CHEMOTHERAPY Table 1 Experimental groups for active systemic anaphylaxis in guinea pigs : Single dosage Fig. 2 Schedule for active systemic anaphylaxis
988 CHEMOTHERAPY NOV. 1971
988 CHEMOTHERAPY NOV. 1971 VOL. 19 NO. 8 CHEMOTHERAPY 989 Effect of medium-ph and inoculum size on activity of SB-PC heart infusion agar, mcg/ml Sensitivity distribution of Staphylococci to SB-PC in surgical
CHEMOTHERAPY AUG. 1982 VOL. 30 NO. 8 CHEMOTHERAPY Fig.1 Relation between various-closis of cefazolin and detection rate of organisms in heart blood of dying mice with E. coli and P. aeruginosa infection
1) Roth, J., Glick, S. M., Yalow, R. S. and Berson, S. A.: Hypoglycemia: A potent stimulus to secretion of growth hormone. Science, 140, 987-988, 1963. 2) Ogawa, N.: Routine Ultramicro-Measurement of Human
CHEMOTHERAPY aureus 0.10, Enterococcus faecalis 3.13, Escherichia coli 0.20, Klebsiella pneumoniae, Enterobacter spp., Serratia marcescens 0.78, Prote
aureus 0.10, Enterococcus faecalis 3.13, Escherichia coli 0.20, Klebsiella pneumoniae, Enterobacter spp., Serratia marcescens 0.78, Proteus mirabilis 3.13, Proteus vulgaris 1.56, Citrobacter freundii 0.39,
Key words: Antibodies to Leptospira, Tokyo, Uveitis
Key words: Antibodies to Leptospira, Tokyo, Uveitis Fig. 1 Distribution of Antibody Titers in Age Decade Fig. 3 Distribution of Antibody Titers in each Strain Fig. 2 Correlation between Antibody Titers
CHEMOTHERAPY APRIL 1992 Table 2. Concentration of meropenem in human prostatic fluid Table 1. Background of 21 chronic complicated UTI cases * NB + BPH, NB + Kidney tumor, NB + Kidney tuberculosis Table
DISTRIBUTION OF NEUROPEPTIDES IN THE INFERIOR NASAL TURBINATE MUCOSA OF PATIENTS WITH ALLERGIC RHINITIS KAZUHIRO YAMAMOTO. M.D. Department of Otolaryngology, School of Medicine, Kitasato University, Sagamihara
Table 1. Influence of urine ph on MBCs of new quinolones against Escherichia coli NIHJ JC-2 and Pseudomonas aeruginosa 18S; MBCs in urine were compared with those in Miieller-Hinton broth. Table 2. Influence
VOL.42 S-1
CHEMOTHERAPY APR. 1994 VOL.42 S-1 CHEMOTHERAPY APR. 1994 Table 1. Criteria for evaluation of clinical efficacy by the Japanese Society of Oral and Maxillo-Facial Surgeons Grades of symptoms and numerical
Key words: Neonate, Intestinal flora, Infection, Bifidobacterium
Key words: Neonate, Intestinal flora, Infection, Bifidobacterium Table 1 Media of aerobic culture (37 Ž 24 hrs) Table 2 Media of anaerobic culture (37 Ž 48 hrs ) Table 3 Methods for analysis of fecal flora
Fig. 1 A: Effects of intramuscular injection of glucagon on the blood glucose levels (changes from basal, ƒ BG) as compared with effects of scopolamin
Fig. 1 A: Effects of intramuscular injection of glucagon on the blood glucose levels (changes from basal, ƒ BG) as compared with effects of scopolamine butylbromide during upper gastrointestinal endoscopy.
Key words: E. coli O 157: H7, fosfomycin, verotoxin, mouse infection
Key words: E. coli O 157: H7, fosfomycin, verotoxin, mouse infection Table 1. Bacterial cell counts in feces of mice infected with Esclwrichia coli O 157: H7 NK2 before and during oral dosing with fosfomycin
Osamu NEMOTO, M.D. Clinical and Bacteriological Research of Sucrose/ Povidone-Iodine Ointment (U-PASTA kowa) for Pressure Sores and Skin Ulcers Osamu Nemoto Department of Dermatology,Tonan Hosptal
VOL.30 NO.12 CHEMOTHERAPY Fig. 1 Effect of temperature on the growth curve of A. calcoaceticus A. calcoaceticits Ac 54 A. calcoacetictts Ac 164 Fig. 2 Effect of medium ph on the growth curve of A. calcoaceticus
Key words: syphilis, anti- Treponema pallidum-igm, purified antigen, serodiagnosis, TPHA Table 1 Influence of purification of Tp antigen by Hypaque and MgC12 on TPHA titer and on M/G ratio in primary
Key words: Phagocytosis, Pseudomonas aeruginosa, OEP, LPS, Anti-Pseudomonas globulin
Key words: Phagocytosis, Pseudomonas aeruginosa, OEP, LPS, Anti-Pseudomonas globulin Table 1 Effect of heated serum on phagocytosis of Pseudomonas aeruginosa (serotype G) by PMNs Difference between heated-and
VOL. 40 S- 1 Table 1. Susceptibility of methicillin-resistant Staphylococcus aureus to meropenem Table 2. Coagulase typing of methicillin-resistant St
CHEMOTHERAPY VOL. 40 S- 1 Table 1. Susceptibility of methicillin-resistant Staphylococcus aureus to meropenem Table 2. Coagulase typing of methicillin-resistant Staphylococcus aureus CHEMOTHERAPY Table
b) Gram-negative bacteria Fig. 2 Sensitivity distribution of clinical isolates : E. coli Fig. 3 Sensitivity distribution of clinical isolates : Pseudomonas Fig. 1 Sensitivity distribution of clinical isolates
;~ (Summary) The Study on the Effects of Foot Bathing on Urination Kumiko Toyoda School of Human Nursing, University of Shiga Prefecture Background Foot bathing is one of the important nursing care for
Key words: Disinfectants, Gram negative rods, Bactericidal effect P. aeruginosa 1, P. fluorescens 20 P. putida 179, P. cepacia 216 P. maltophilia 227,
Key words: Disinfectants, Gram negative rods, Bactericidal effect P. aeruginosa 1, P. fluorescens 20 P. putida 179, P. cepacia 216 P. maltophilia 227, P. putrefaciens 279 A. faecalis 120, A. ordrans 114
Title 歯性病巣の関連する皮膚疾患におけるビオチンの効用 Author(s) 高橋, 愼一 ; 川島, 淳子 ; 森本, 光明 ; 山根, 源之 Journal, (): - URL Right Posted at the Inst
Title 歯性病巣の関連する皮膚疾患におけるビオチンの効用 Author(s) 高橋, 愼一 ; 川島, 淳子 ; 森本, 光明 ; 山根, 源之 Journal, (): - URL http://hdl.handle.net/10130/526 Right Posted at the Institutional Resources for Unique Colle Available from
coccus aureus Corynebacterium sp, Haemophilus parainfluenzae Klebsiella pneumoniae Pseudornonas aeruginosa Pseudomonas sp., Xanthomonas maltophilia, F
VOL.43 S-1 coccus aureus Corynebacterium sp, Haemophilus parainfluenzae Klebsiella pneumoniae Pseudornonas aeruginosa Pseudomonas sp., Xanthomonas maltophilia, Flavobacter- Table 1. Concentration of grepafloxacin
1) Michaelis L. Biochem Z., 59, 78, 1914. 2) Ferris H. C. Dent. Cosmos Phila., 63, 10, 93, 1921. 3) Bloomfield A. L. Bull Johns Hopk. Hosp. Bait., 31, 118, 1920. 4) Starr H. C. J. Biol. Chem. Bait., 54,
Effect of Trimoprostil on Gastric Secretion Takeshi KAWAMURA * Hiroko EBINA * Fumiaki KOIZUMI * and Akira ISHIMORI * *Department of Clinical and Labor
Effect of Trimoprostil on Gastric Secretion Takeshi KAWAMURA * Hiroko EBINA * Fumiaki KOIZUMI * and Akira ISHIMORI * *Department of Clinical and Laboratory Medicine University School of Medicine, Tohoku
名称未設定-1
Study on Clinical Factors Affecting the Fungal Culture Test - Relevance of Dry Mouth - Yoshiko YAMAMURA, Yukihiro MOMOTA, Hideyuki TAKANO, Koichi KANI, Katsumi MOTEGI, Fumihiro MATSUMOTO, Masayuki AZUMA
Table 1 Characteristics of the study participants in Imari municipal hospital
Key words: tuberculosis, booster phenomenon, two-step tuberculin test Table 1 Characteristics of the study participants in Imari municipal hospital Fig. 1 Frequency distributions of size of the first tuberculin
東洋医学雑誌
Vol.67 No.2 123-130, 2016 Akiyo GUSHI a Chihaya KORIYAMA b Ryo YOSHINAGA c Hiromi YANO c Junichi TSUMAGARI d Eiichi TAHARA c a Gushi Dermatological Clinic, 45-3 Higashiohsyoji, Satsumasendai city, Kagoshima
The Eevaluation One Bottle Type Silane Coupling Agents Masahiro Aida, Hideo Kanaya, Taira Kobayashi, Keiji Utsugizaki, Yoshizumi Murata, Tohru Hayakaw
The Eevaluation One Bottle Type Silane Coupling Agents Masahiro Aida, Hideo Kanaya, Taira Kobayashi, Keiji Utsugizaki, Yoshizumi Murata, Tohru Hayakawa* and Kozo Horie* Abstract: Here is investigated the
Effects of Light and Soil Moisture Condition on the Growth of Seedlings for Quercus serrata and Quercus variabilis NISHIMURA, Naoyuki*, OTA, Takeshi**
Effects of Light and Soil Moisture Condition on the Growth of Seedlings for Quercus serrata and Quercus variabilis NISHIMURA, Naoyuki*, OTA, Takeshi**, SAKAMOTO, Keiji*** and CHIBA, Kyozo*** Key words:
"G um exp." in the table means before the gum chewing experiment, and "Cont exp." in the table means Table 1. Rest values of heart rate (HR), coefficient of variation in RR (CVRR), wave height of plethysmogram
Key wards: cyclophosphamide, neutropenic mice, Pseudomonas aeruginosa, experimental pyelonephritis, G-CSF
Key wards: cyclophosphamide, neutropenic mice, Pseudomonas aeruginosa, experimental pyelonephritis, G-CSF Pseudomonas aeruginosa Fig. 1 Method of administration of cyclophosphamide and G-CSF CPM group
Changes in Electrodermal Activity Associated with Candies and Chewing Gum Chewing Satoshi Beppu, Takeshi Morita*, Susumu Igarashi **, Kanichi Seto* an
Changes in Electrodermal Activity Associated with Candies and Chewing Gum Chewing Satoshi Beppu, Takeshi Morita*, Susumu Igarashi **, Kanichi Seto* and Yosihiro Amemiya Abstract: This study was designed
5) Kawada T, Hagihara K, Iwai K (1986) Effects of capsaicin on lipid metabolism in rats fed a high fat diet. J Nutr 116 : 1272-8. 6) Kawada T, Watanabe T, Takaishi T, Tanaka T, Iwai K (1986) Capsaicin-induced
Chlamydia trachomatis monomer/polymer Key words : chlamydial urogenital infection monomeric IgA, polymeric IgA, serum IgA specific for C. trachomatis,
Chlamydia trachomatis monomer/polymer Key words : chlamydial urogenital infection monomeric IgA, polymeric IgA, serum IgA specific for C. trachomatis, Fig. 1 Assay Procedures of C. trachomatis Specific
日本化学療法学会雑誌第53巻第S-3号
moxifloxacin in vitro moxifloxacin in vitro 17 9 6 17 11 21 moxifloxacinmflx in vitro cefdinir CFDNclavulanic acidamoxicillincvaampcclarithromycincamclindamycincldm levofloxacinlvfx 1MFLX Clostridium clostridiiformeclostridium
untitled
1988 2000 2002 2004 2006 2008 IFN Lamivudine Adefovir Entecavir 1 Total number 560 Sex (male/female) 424/136 Age (years)* 38 (15-68) Duration of treatment (weeks)* 26 (1-592) Follow-up time (years) 75(05-21
Key words : 7432-S, Oral cephem, Urinary tract infection Fig. 1. Chemical structure of 7432-S.
Key words : 7432-S, Oral cephem, Urinary tract infection Fig. 1. Chemical structure of 7432-S. Table 1. Clinical summary of acute uncomplicated cystitis patients treated with 7432-S UTI : Criteria by the
Fig.1 MICs of penicillins against 24 strains of B. pertussis Fig.2 MICs of cepherns against 24 strains of B. pertussis Fig.3 MICs of macrolides against 24 strains of B. pertussis Fig.4 MICs of nalidixic
EVALUATION OF NOCTURNAL PENILE TUMESCENCE (NPT) IN THE DIFFERENTIAL DIAGNOSIS OF IMPOTENCE Masaharu Aoki, Yoshiaki Kumamoto, Kazutomi Mohri and Kazunori Ohno Department of Urology, Sapporo Medical College
Key words: Surfactant, Tween, Legionella
Key words: Surfactant, Tween, Legionella Fig. 1 Inhibitory Activity of Various Tween Against Legionella pneumophila Fig. 2 Inhibitory Activity of Various Tween Against Legionella bozemanii Fig. 3 Inhibitory
Key words : R-plasmid, Urinary tract infection, E. coli Fig. 1. MIC distribution against E. coli isolated from urinary tract (366 strains) and isolation - frequencies of drug-resistant strains Table 1.
Effect of Sympathetic and parasympathetic agents on cholesterol metabolism in mice salivary glands. Eriko, NEZU and Haruo, NAKAMURA (Department of Ora
Effect of Sympathetic and parasympathetic agents on cholesterol metabolism in mice salivary glands. Eriko, NEZU and Haruo, NAKAMURA (Department of Oral Physiology, Hokkaido University School of Dentistry,
Table 1. Case Distribution of Pulmonary Tuberculosis
267 Kekkaku Vol. 56, No. 5 IMMUNOLOGICAL STUDY ON THE BACKGROUND FACTORS OF INTRACTABLE PULMONARY TUBERCULOSIS PATIENTS 6 Shinobu TAKENAKA* (Received for publication December 3, 1980) Immunological studies
VOL. 17 NO. 7 CHEMOTHERAPY 1305 1) W. BRumFirr et al. : Clinical and laboratory studies with carbenicillin. Lancet 1: 1289~ 1293, 1967 2) E. T. KNUDSEN et al. : A new semisynthetic penicillin active against
Experimental and Clinical Studies of Pregnant Hypertension Takashi SHIMAZU Department of Obstetrics and Gynecology, Osaka City University Medical Scho
Experimental and Clinical Studies of Pregnant Hypertension Takashi SHIMAZU Department of Obstetrics and Gynecology, Osaka City University Medical School While the problem of late pregnant hypertension
1) University Group Diabetes Program: A study of hypoglycemic agents on vascular complica- in patients with adult-onset tions diabetes. I. Design, methods and baseline results. Diabetes 19 (suppl. 2):
Table 1. Antibacterial activitiy of grepafloxacin and other antibiotics against clinical isolates
Table 1. Antibacterial activitiy of grepafloxacin and other antibiotics against clinical isolates Table 2-1. Summary of patients treated with grepafloxacin for respiratory infection 1) Out: outpatient,
Table 2 Cases of Nail Deformity Associated with upward Distortion of Distal Soft Tissue No. Age Sex Affected RegionsDuration Results M Both grea
Table 2 Cases of Nail Deformity Associated with upward Distortion of Distal Soft Tissue No. Age Sex Affected RegionsDuration Results 1. 49 M Both great toes 2 years Cured after 4 months 2. 11 F Both great
STUDIES ON THE RELATION BETWEEN LATE DUMPING SYNDROME AND GLUCAGON RESPONCES TO GLUCOSE Taisuke MATSUI The First Department of Surgery, Nara Medical U
STUDIES ON THE RELATION BETWEEN LATE DUMPING SYNDROME AND GLUCAGON RESPONCES TO GLUCOSE Taisuke MATSUI The First Department of Surgery, Nara Medical University, Kashihara (Director: Prof. H. Nakano) This
CHEMOTHERAPY APRIL 1992 VOL. 40 S- 1 Table 1-1. Comparative in vitro activity of meropenem against clinical isolates CNS: coagulase-negative staphylococci CHEMOTHERAPY APRIL 1992 Table 1-2. Comparative
Fig. 1 Chemical structure of TE-031 Code number: TE-031 Chemical name: (-) (3R, 4S, 5S, 6R, 7R, 9R, 11R, 12R, 13S, 14R)-4-[(2, 6-dideoxy-3-C-methyl-3-
Fig. 1 Chemical structure of TE-031 Code number: TE-031 Chemical name: (-) (3R, 4S, 5S, 6R, 7R, 9R, 11R, 12R, 13S, 14R)-4-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl) oxy]-14-ethyl-12,
Studies on Mild School Myopia Part II. The Amplitude of Accmmodation in Mild School Myopia By Ling Nai Kay Department of Ophthalmology Okayama University Medical School (Director: Prof. Goro Akagi) By
Table 1.Distribution and number of cases with acute upper respiratory tract infections classified according to antimicrobial agents administered Table 2. Distribution of cases which were enrolled to set
Mikio Yamamoto: Dynamical Measurement of the E-effect in Iron-Cobalt Alloys. The AE-effect (change in Young's modulus of elasticity with magnetization
Mikio Yamamoto: Dynamical Measurement of the E-effect in Iron-Cobalt Alloys. The AE-effect (change in Young's modulus of elasticity with magnetization) in the annealed state of iron-cobalt alloys has been
1) Barat, I. u. Wagner, R.: Brauer, Beitrage Zur Klinik der Tub., Bd. 71 (1929) 2) Warnecke, F.: Zeitschr. f. Tbk. Bd. 54 (1929) 3) Leoni, Alfonso: Zbl. f. g. Tbk. Forsch. Bd. 33 (1930) 4) Jalavisto, Eva
CHEMOTHERAPY FEB Table 1. Activity of cefpirome and others against clinical isolates
VOL.39 S-1 CHEMOTHERAPY FEB. 1981 Table 1. Activity of cefpirome and others against clinical isolates VOL.39 S-1 CHEMOTHERAPY FEB. 1991 72 M, 55.5 kg 66 F, 53 kg Chronic bronchitis Bronchopneumonia Peak
Key words: bacterial meningitis, Haemophilus influenzae type b, Streptococcus pneumoniae, rapid diagnosis, childhood
Key words: bacterial meningitis, Haemophilus influenzae type b, Streptococcus pneumoniae, rapid diagnosis, childhood Fig.1 Distribution of the cases with bacterial meningitis by age and pathogens Chiba
_’£”R‡Ù‡©
29 31 38 2008 31 1) 2) 2) 3) 2) 1) 2008 302008 12 Activities of Daily Living ADL ADL 42 ADL ADL 1990 QOL Quality of Life QOL 1 QOL // 2 Activity of Daily Living ADL Performance Status PS ADL 3 1) 2) 3)
VOL. 23 NO. 3 CHEMOTHERAPY 1067 Table 2 Sensitivity of gram positive cocci isolated from various diagnostic materials Table 3 Sensitivity of gram nega
1066 CHEMOTHERAPY MAR. 1975 Table 1 Sensitivity of standard strains VOL. 23 NO. 3 CHEMOTHERAPY 1067 Table 2 Sensitivity of gram positive cocci isolated from various diagnostic materials Table 3 Sensitivity
Jpn. J. Clin. Immun., 13 (4) : 320 `327, 1990. The protective effects of Sho-saiko-to in an experimental, immunologically-induced allergic hepatic cell injury Yasuhiro Mizoguchi, Tohkan Shin, Norifumi
Fig.2. Sensitivity distribution of clinical isolates of S. epidermidis (24 strains, 106 CFU/ml) Staphylococcus aureus Staphylococcus epider- midis Ent
Fig.2. Sensitivity distribution of clinical isolates of S. epidermidis (24 strains, 106 CFU/ml) Staphylococcus aureus Staphylococcus epider- midis Enterococcus faecalis Klebsiella pneumoniae, Morganella
Title 個人 集団レベルの心理社会的学校環境が生体的ストレス反応に及ぼす影響 Author(s) 高倉, 実 ; 小林, 稔 ; 和氣, 則江 ; 安仁屋, 洋子 Citation Issue Date 2007-03 URL http://hdl.handle.net/20.500.12000/ Rights Abstracts of Research Project, Grant-in-Aid
Table 1.Resistance criteria Fig.1.The resistance rates of piperacillin,ceftazidime, cefsulodin,imipenem,aztreonam,gentamicin,tobramycin,amikacin,isepamicin,fosfomycin and ofloxacin against 2,793 strains
Vol. No. Honda, et al.,
A Study of Effects of Foot Bath before Exercise on Fall Prevention Yoko Honda Yoko Aso Aki Ibe Megumi Katayama Tomoko Tamaru Key Words fall prevention, foot bath, elderly, fall prevention programs Honda,
Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic c
Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic clinic, Department of Ophthalmology, (Director: Prof
1) Bradley EThe Relation of Cellular Element of the Saliva to Caries, Oral Surg., Oral Med., & Oral Path., 1, 423, 1948. 4) Iusem: A Cytology study of Cornification of the Oral Mucosa in wumen, Oral Surg.,
CHEMOTHERAPY JUNE 1987 Table1 Media used *BHIB, brain heart infusion broth (Difco); /3 -NAD, S -nicotinamidoadeninedinucleotide (Sigma Chemical Co.);
VOL.35 S-2 CHEMOTHERAPY Fig.1 Chemical structure of carumonam CHEMOTHERAPY JUNE 1987 Table1 Media used *BHIB, brain heart infusion broth (Difco); /3 -NAD, S -nicotinamidoadeninedinucleotide (Sigma Chemical
March Social Decision Scheme Davis a theory of social decision scheme n AA An pp pn pppn r AA An PP Pn d d dn d d dn PPPn πππm dm dmdmn r πi rrrn pr p r pn rn r AA An rr rn rr rnr nr r m nr m r nr m pp
日本消化器外科学会雑誌第25巻第11号
Key words: intestinal nerve plexus, hypoxic perfusion, immunohistochemistry, 5-100 protein Table I (A) Sroo staining reactivity of nerve tissue normal partly mildly declined all mildly declined partly
19 OUR EXPERIENCE IN COMBINED BALNEO AND CHRYSOTHERAPY FOR RHEUMATOID ARTHRITIS by Hidemitsu EZAWA (Director: Prof. Hiroshi MORI NAG A), Department ofinternal Medicine, Institute for Thermal Spring Research,
The Japanese Journal of Experimental Social Psychology. 2002, Vol. 41, No. 2, 155-164 V. 1986 An introduction to human memory. Routledge & Kegan Paul.) Hay, D. C., & Young, A. W. 1982 The human
The Japanese Journal of Psychology 1989, Vol. 60, No. 4, Changes of body sensation through muscular relaxation: Using the method of measuring
The Japanese Journal of Psychology 1989, Vol. 60, No. 4, 209-215 Changes of body sensation through muscular relaxation: Using the method of measuring tactile two-point lien Yoshitaka Konno (Faculty of
J. Smooth Muscle Res. (Jap. Section) 5: J-59--J-67, 2001 URODYNAMIC STUDY IN DIAGNOSIS OF DIABETIC DYSURIA Minoru SATO First Department of Urology, To
J. Smooth Muscle Res. (Jap. Section) 5: J-59--J-67, 2001 URODYNAMIC STUDY IN DIAGNOSIS OF DIABETIC DYSURIA Minoru SATO First Department of Urology, Toho University School of Medicine, 6-11-1 Omori-nishi,
Web Stamps 96 KJ Stamps Web Vol 8, No 1, 2004
The Journal of the Japan Academy of Nursing Administration and Policies Vol 8, No 1, pp 43 _ 57, 2004 The Literature Review of the Japanese Nurses Job Satisfaction Research Which the Stamps-Ozaki Scale
Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution of female patients with blad
Key words: Female with bladder irritability, Subjective symptoms, Pyuria, Bacteriuria Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution
ANTI-BACTERIAL DEFENSE MECHANISMS OF THE URINARY TRACT CONSTRUCTED FROM INTESTINAL SEGMENTS Studies on Cell Population and Phagocytotic Activity of Urinary Leucocytes, and Bacterial Growth in Urine Shinnosuke