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47 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /., No.++, /*3/+/ (,**1) 509 Current Situation on Tran Fatty Acid Issues Tadahiro Nagata Department of Human Nutrition, Seitoku University, //* Iwase, Matsudo, Chiba,1+2///,*,**. *1 2 +, -,1+2/// //* Corresponding author nagatatadahiro@yahoo.co.jp + ++, - 2 + Web Page. +, + /,**- 0,,+ hydrogenation hard-

510 /. ++,**1 ++ 48 + ening +333 1,/.+.1.* 2.,,/.0,/.-.0.+ -3.-.0.0,,.- -+.+ 2 *..+-./,* +.* +*.* +. +.,-+., +* *..-.2 2 *..1.-. *..,.+/. *.-+.0.,, C+2 : + ++-trans, C+2 : + 3-trans,,/,

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512 /. ++,**1 ++ 50,/ +, RS NO, +-+. NO, C,* :. +.-trans +/ +0 - -+ GC, C+2 AOCS Ce +h-*/ Ce +f-30,**, AOAC C+2 : + 3-trans AOCS +2 GC GC Ag-TLC TLC GC GC - -, LC +1. CAD : Charged Aerosol Detector GC C+2 : + GC. CAD-HPLC..+,**/ LDL +2,* +3,* 0/ LDL HDL,+,./ +*,, BfR ++*

51 : 513 + + + :g * *4,1 *422 *43+ *4+1 *4,/ *4+2 *4,1 *4*2 *4+- *41* +4-+ +4/0 *,-,,. 2. +.,/,, EFSA,0,.,,**- FAO WHO Joint WHO/FAO Expert Consultation on Diet, Nutrition and the Prevention of Chronic Diseases +,1, +,,2.-,**1,3 + *.1* g *.- +.- g *.0,, +333 +./0g *.1 0*,/ +/ /.2 g,.0.*,+ +1 2 / -* +33/+330 *.3,**, *./ +33/+330,,**, +./ +33/+330 +./ +333,**+ +, +.* g +, g 2.0,*,.. g +.* g M L + + +.. FDA - 0** +,**,/* /** /.+2 +.. 31./,.+ -+

514 /. ++,**1 ++ 52.* +,.+ LDL -+,**/*1 -, -- + : http ://www. ma#.go.jp/syohi_anzen/trans_fat/index.html, +3 0,+ : http : //www.fsc.go.jp/sonota//. kai-factsheets-trans.pdf - : http : //nfri.naro.a#rc.go.jp/yakudachi/transwg/index. html. : http : //nfri.naro. a#rc.go.jp/yakudachi/transwg/transhyo.html / Codex Alimentarius Commission, Repot of the -/th Session of the Codex Committee on Food Labeling (ALINORM *0/,3/,,). 0 CFSAN O$ce of Nutritional Products, Labeling and Dietary Supplements, Questions and Answers about Trans Fat Nutrition Labeling : http : //www.cfsan.fda. gov/~dms/qatrans,.html 1.2 +, +.+++.+. +333 2 +2 http : / / www. fsc. go. jp / senmon / kagakubusshitu / k-dai. / kagaku.-toujitusiryou.pdf 3 Codex Committee on Food Labeling -/th Session, Matters Referrers by FAO and WHO : Implementation of the Global Strategy on Diet, Physical Activity and Health (CX/FL *1/-//-). +* Liu, W., Inbaraj, B., Chen, B., Analysis and formation of trans fatty acids in hydrogenated soybean oil during heating, Food Chem., +*., +1.*+1.3 (,**1). ++,**0 : http : //nfri.naro.a#rc.go.jp/ research/seikatenji/,**0/pdf/p,**0*/,.pdf +, Sgoutas,B. and Kummerow,F., Cis-Tans isomerization of unsaturated fatty acid methyl esters without double bond migration, Lipid,. (.),,2-,21 (+303). +- Jiang,H., et al., Nitrogen dioxide induced cis-transisomerization of arachidonic acid within cellular phospholipids, J. Bio. Chem.,,1. (,-), +0,-/+0,.+ (+333). +. Zghibeh,C., et al., Determination of trans-arachidonic acid isomers in human blood plasma, Anal. Biochem., -,,, +-1 +.. (,**.). +/ Zamtonin, L., et al., Occurrence of trans fatty acids in rat fed a trans-free diet : A free radical-mediated formation? Free Rad. Biol. Med.,.*, +/.3+//0 (,**0). +0 Barui, M., et al., E#ect of irradiation on trans fatty acids formation in ground beef, Radiation Physics and Chemistry, 0-, --1-.* (,**,). +1 +2 HPLC : http : //nfri.naro.a#rc.go.jp/research/seika/seikah+2/pdf/p

53 : 515,2.pdf +2 http : //www. nap.edu/openbook.php?isbn*-*3*2/-1-&page.,- +3 Oh, K., et al., Dietary fat intake and risk of coronary heart disease in women :,* years of follow-up of the nurses health study, Am. J. Epidemiol., +0+ (1), 01,013 (,**/).,* ++* -,.*,.+,**1,+ Moza#arian, D., Katan, M.B., Ascherio, A., Stampfer, M. J. and Willett, WC., Trans fatty acids and cardiovascular disease, New Engl. J. Med. -/. (+/), +0*++0+- (,**0).,, Stender, S. and Dyerberg, J., Influence of trans fatty acids on health, Ann Nutr Metab.,.2 (,), 0+00 (,**.).,- No. 0,**0,**0. *-. +/ : http : //www.nihs.go.jp/hse/food-info/ foodinfonews/,**0/foodinfo-0_,**0.pdf,. Salmeron, J., et al., Dietary fat intake and risk of type, diabetes in women, Am. J. Clin. Nutr., 1- (0) :+*+3,0 (,**+).,/ Weiland, S., Mutius, E., Husing, A. and Asher, M., Intake of trans fatty acids and prevalence of child ashema and allergies in Europe, Lancet, -/-,,*.*,3.+ (+333).,0 EFSA NDA Panel,**. 1 2 : http : //www.efsa.europa.eu/en/science/nda/ nda_opinions/others//22.html,1 WHO technical report series3+0, Diet, nutrition and the prevention of chronic disease : http : //www.who.int/ hpr/nph/docs/who_fao_expert_report.pdf,2 : http : // www. nihs. go. jp / hse / food-info / foodinfonews / index. html,3 : http : //www.fsc.go.jp/senmon/ kagakubusshitu/k-dai./kagaku.-siryou+-+.pdf -* FDA Consumer magazine, September-October,**- Issue, Revealing Trans Fats : http : //www.fda.gov/fdac/ features/,**-//*-_fats.html -+ +3 -,- : http : //www.ma#.go.jp/ syohi_anzen/profiles/transfattyacid.pdf -, : http : //www.a#tis.or.jp/project/ hightech/h+1/pdf/+13-.pdf -- : http : //www.ma#.go.jp/syohi_anzen/risk/ totaldiet_gl.pdf +3 2 -*