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1 QOL 1950 Cardiac Arrhythmia Suppression Trial 10 WPW

2 Cardiac Arrhythmia Suppression Trial CAST CAST Scheinman Borggrefe 7 WPW Kent 4 mm large-tip Jackman 8

3 , khz WPW 1 WPW Kent Ë 2 WPW Ë WPW 90 WPW 1,000 2, 3 11,12 2 Wolf-Perkonson-White QRS RR RR 230 msec

4 48 3 ABL USER HRA Abl His RV

5 QRS slow potential /

6 50 6 ab1-2 SP slow potential 7 3 QRS 5

7 /

8 QRS QRS QRS 12 Purkinje CCU 17 QRS

9 53 11 QRS 12 2 ABL 37 msec

10 , Brugada 20

11 QRS 3

12 Brugada Burgada 20 1) Ijiri H, Komori S, Kohno I, Sano S, Yin DF, et al.: Improvement of exercise tolerance by single-lead VDD pacemaker: Evaluation using cardiopulmonary Exercise Test. PACE 23: , ) Coumel P, Leenhardt A: Mental activity, adrenergic modulation, and cardiac arrhythmias in patients with heart disease. Circulation. 83 (4 Suppl): II58 70, ) Mukharji J, Rude RE, Poole WK, Gustafson N, Thomas LJ Jr, et al.: Risk factors for sudden cardiac death after myocardial infarction: Two-year followup. Am J Cardiol 54: 31 36, ) Cardiac Arrhythmia Suppression Trial (CAST) Investigators: Increased mortality due to encainide or flecainide in a randamized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 321; , ) Beazell J, Tan K, Criley O, Schulman J: The electrosurgical production of heart block without thoracotomy. Western Society for Clinical Research: 137A, ) Scheinman MM, Evans-Bell T, Executive Committee of the Percutaneous Cardiac Mapping and Ablation Registry: Catheter ablation of the atrioventricular junction: A report of the percutaneous cardiac mapping and ablation registry. Circulation 70: , ) Borggrefe M, Budde T, Podczech A, Breithardt G: High frequency alternating current ablation of an accessory pathway in humans. J Am Coll Cordiol 10: , ) Jackman WN, Wang X, Friday KJ, Roman CA, Moulton KP, et al.: Catheter ablation of accessory pathway (Wolf-Perkinson-White syndrome) by radiofrequency current. N Engl J Med 324: , ) Haines DE, Verow AF: Observations on electrotissue interface temperature and effect on electrical impedance during radiofrequency ablation of ventricular myocardium. Circulation 82: , ) Haines DE: Determinants of lesion size during radiofrequency catheter ablation: the role of electrode-tissue contact pressure and duration of energy delivery. J Cardiovasc Electrophysiol 2: , ) Sano S, Komori S, Amano T, Kohno I, Ishihara T, et al.: Prevalence of ventricular preexcitation in

13 57 Japanese schoolchildren. Heart 79; , ) Sano S, Komori S, Amano T, Tamura K: Followup of ventricular preexcitation in Japanese schoolchildren. Lancet 351, 1789, ) Haissaguerre M, Gaita F, Fisher B: Elimination of atrioventricular nodal reentrant tachycardia using discrete slow potentials to guide application of radiofrequency energy. Circulation 85: , ) Kohno I, Ishihara T, Umetani K, Sawanobori T, Ijiri H, et al.: Pathological findings of isthmus between the inferior vena cava and tricuspid annuals ablated by radiofrequency application. PACE 23: , ) Komori S, Takeda S, Tachibana K, Yamamoto K, Sano S, et al.: Exercise-induced Monomorphic ventricular tachycardia from left ventricle outflow tract. Jpn Circ J 62; , ) Morady F, Harvey M, Kalbfleisch SJ: Radiofrequency catheter ablation of ventricular tachycardia in patients with coronary artery disease. Circulation 87: , ) Volpi A, Cavalli A, Franzosi MG, Maggioni A, Mauri F, et al.: One-year prognosis of primary ventricular fibrillation complicating acute myocardial infarction. Am J Cardiol 63: , ) Moss AJ, Hall WJ, Cannom DS, Daubert JP, Haggins SL, et al. for the Multicenter Autonomic Defibrillator Implantation Trial Investigators: Improved survival with an implanted defibrillator in patients with coronary artery disease at high risk for ventricular arrhythmia. N Engl J Med 335: , ) The Antiarrhythmics Versus Implantable Defibrillators (AVID) Investigators: A comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from nearfatal sustained ventricular arrhythmias. N Engl J Med 337: , 1997.

C/NC : committed/noncommitted

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