58 5 260 270 2015 Behçet Behçet 58 4 Sjögren IgG4 5 Behçet Behçet Behçet 1937 Hulusi Behçet 4 1 25 19,147 HLA B51 A26 2 HLA B51 4 1 Behçet Behçet Behçet Behçet 2 3 Recurrent Aphthous Stomatitis RAS 26 260
Behçet 58 5 1 2010 1 1 2 a b c 3 a b cab ab 4 2 1 2 3 4 5 3 1 4 2 a 3 2 2 b 1 2 3 4 a b c 3 4 Behçet RAS 1 2 3 5 Behçet Behçet Behçet 2 Behçet 2 1 49 6 3 261 27
58 5 2 3 1 2 3 4 5 Koplik 6 Forschheimer 7 8 9 10 11 GVHD 1214 13 Behçet 14 Sweet 15 Crohn 16134 17 18 SLE 19 1 Prednisolone 15mg/day loxoprofen C B1 B6 B12 2 prednisolone betamethasone 1.5mg/day 4 25kg Behçet 173cm 63kg 36.2 97/68mmHg 96 / WBC 6,600/μl Hb 15.1g/dl Plt 29.0 /μl AST 39IU/l ALT 44IU/l LDH 189IU /l ALP 196IU/l γ GT 61IU/l T Bil 0.8mg/dl TP 7.4g/dl Alb 3.9g/dl UN 43mg/dl Cr 1.09mg /dl Fe 91μg/dl Zn 108μg/dl Cu 121μg/dl CRP 0.42mg/dl IgG 1,038mg/dl IgA 454mg/dl IgM 55mg/dl 40 β D 4.0 pg/ml HIV HZV IgM 0.18 HZV IgG 2.0 1 3.0U/ml 3 1,000.0U/ ml CT 25cm 28 262
Behçet 58 5 3 4 Behçet MAGIC Crohn HIV PFAPA Marshall B1 B2 B6 B12 HLA T CD4 CD8 β Behçet Crohn 1 Behçet Dsg Dsg1 Dsg3 Dsg3 Dsg1 Dsg3 Dsg3 5 263 29
58 5 1 1 2 34 3 2 1 39 Behçet 150cm 44kg 38.2 112/68mmHg 70 / 5mm 10mm WBC 3,700/μl Hb 11.1g/dl Plt 22.9 /μl AST 30IU/l ALT 22IU/l LDH 326IU/l ALP 362IU/l γ GT 48IU/l T Bil 0.3mg/dl TP 6.9 g/dl Alb 3.6dl UN 9mg/dl Cr 0.69mg/dl CRP 1.79mg/dl IgG 1291mg/dl IgA 185mg/dl IgM 158 mg/dl ds DNA 10U/ ml Sm 7.0U/ml SS A 7.0U/ml C ANCA 1.0EU P ANCA 1.0EU HSV IgM 0.44 HSV IgG 259EB VCA IgG40 EB VCA IgM 10 EB EBNA40 CMV IgM 1.07/ CMV IgG 9.7 1.050, PH 8.5 / CT Behçet 2 Behçet Tzanck 7 30 264
Behçet 58 5 CRP 0.15mg/dl self limiting 11 Behçet 6 7 1972 40 1 2 10 8 Behçet Behçet Behçet Behçet 1877 Hutchinson 9 1991 12 X CD4 T /CD8 T Th 1 ACE Ca ACE 10 25 24,487 1 3 39 2 1 Cefditoren Pivoxil 7 3 38 23 24 155cm 48kg 36.8 112/62mmHg 86 / 265 31
58 5 2 2 MRI arrow head 2 soft touch 8/10 pin prick 2/10 WBC 41,700/μl Hb 13.9g/dl Plt 28.4 /μl AST 24IU/l ALT 17IU/l LDH 240IU /l ALP 193IU/l γ GT 27IU/l T Bil 0.6mg/dl TP 7.7g/dl Alb 4.2g/dl Amy 169IU/l total S 82 total P 18UN 11mg/dl Cr 0.65mg/dl CRP 0.04 mg/dl IgG 1516mg/dl IgA 180mg/dl IgM 240 mg/dl IgG4 18.5mg/dl RF 2.0IU/ml 40 Homogeneous Speckled SS A 7.0 U/ml SS B 7.0U/ml ACE 28.7U/l 21.4 15.9μg/ml sil 2R 2,490 U/ml IgG 2.0 IgM 0.10 X CT MRI 2 3 2 100 13 arrow head Ga 3 ACEsIL 2R Heerfordt Holter Prednisolone 30mg/day 6 Heerfordt 11 12 2 13 Heer- 32 266
Behçet 58 5 4 McAdam 19 Oka 20 83 76 127 112 57 6 104 44 53 3 97 5.3 1 33 26 89 57 78 6.4 46 3.8 27 13 72 2.1 39 14 56 17 50 20 41 14 65 9.2 46 15 26 11 23 81 6.2 39 17 13 24 7.1 2.9 9.6 6.7 1.7 fordt Darlington 1,000 16 1.6 14 Sjögren Mikulicz McCaffrey 2,319 220 9 4026 13 6 6 4 4 1 15 1923 Jaksch von Wartenhorst 16 1960 Pearson 17 2015 1 1 400 500 18 2 4 19 20 267 33
58 5 5 McAdam 19 Damiani 20 3 1 2 Wegener 239 119 9.022 8 20 Behçet CRP McAdam 19 Damiani 21 56 4 TNF α 34 268
Behçet 58 5 4 4 CT 4 64 3 1 CT MRI prednisolone 40mg/day 5 55 60 63 170cm 70kg 36.8 114/64mmHg 82 / WBC 7,100/μl RBC 410 /μl Hb 11.4g/dl Plt 36.2 /μl AST 26IU/l ALT 18IU /l LDH 206IU/l ALP 215IU/l γ GT 41IU/l T Bil 1.1mg/dl TP 7.4g/dl Alb 3.3g/dl UN 18mg/ dl Cr 0.75mg/dl CRP 2.52mg/dl ESR 76mm/hr IgG 1,522mg/dl IgA 331mg/dl IgM 57mg/dl RF 3.9IU/ml MMP 3 470ng/ml 36.9 121 C ANCA 10EU P ANCA 10EU CT 4 CT air trapping prednisolone 40mg/day 20 CRP 0.50mg/dl 28 MRI prednisolone 35mg/ day 37 32 McAdam Damiani prednisolone MMP 3 3 prednisolone Behçet Behçet Heerfordt 269 35
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