慢性膵炎GL-01.qxd
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2 GERD 26
3 GERD a Spechler SJ, Jain SK, Tendler DA, et al. Racial differences in the frequency of symptoms and complications of gastro-oesophageal reflux disease. Aliment Pharmacol Ther ; 16 : - ; 6 : - Murray LJ, McCarron P, McCorry RB, et al. Prevalence of epigastric pain, heartburn and acid regurgitation in adolescents and their parents : evidence for intergenerational association. Eur J Gastroenterol Hepatol ; 19 : - Kern M, Hofmann C, Hyde J, et al. Characterization of the cerebral cortical representation of heartburn in GERD patients. Am J Physiol Gastrointest Liver Physiol ; 286 : G-G GERD GERD ; 98 : - a Manabe N, Haruma K, Hata J, et al. Difference in recognition of heartburn symptoms between Japanese patients with gastroesophageal reflux, physicians, nurses, and healthy subjects. Scand J Gastroenterol ; 43 : - 27
4 GERD GERD - GERD PPI 28
5 PPI, GERD GERD small study GERD Kiljander TO, Salomaa ER, Hietanen EK, et al. Gastroesophageal reflux in asthmatics : a double-blind, placebo-controlled crossover study with omeprazole. Chest ; 116 : - Larrain A, Carrasco E, Galleguillos F, et al. Medical and surgical treatment of nonallergic asthma associated with gastroesophageal reflux. Chest ; 99 : - Irwin RS, Curley FJ, French CL. Difficult-to-control asthma : contributing factors and outcome of a systematic management protocol. Chest ; 103 : - Irwin RS, French CL, Curley FJ, et al. Chronic cough due to gastroesophageal reflux : clinical, diagnostic, and pathogenetic aspects. Chest ; 104 : - Field SK, Sutherland LR. Does medical antireflux therapy improve asthma in asthmatics with gastroesophageal reflux? : a critical review of the literature. Chest ; 114 : - Littner MR, Leung FW, Ballard ED nd, et al. Effects of weeks of lansoprazole therapy on asthma symptoms, exacerbations, quality of life, and pulmonary function in adult asthmatic patients with acid reflux symptoms. Chest ; 128 : - Kiljander TO, Harding SM, Field SK, et al. Effects of esomeprazole mg twice daily on asthma : a randomized placebo-controlled trial. Am J Respir Crit Care Med ; 173 : - Shimizu Y, Dobashi K, Kobayashi S, et al. A proton pump inhibitor, lansoprazole, ameliorates asthma symptoms in asthmatic patients with gastroesophageal reflux disease. Tohoku J Exp Med ; 209 : - Cremonini F, Wise J, Moayyedi P, et al. Diagnostic and therapeutic use of proton pump inhibitors in non-cardiac chest pain : a metaanalysis. Am J Gastroenterol ; 100 : - Vaezi MF, Richter JE, Stasney CR, et al. Treatment of chronic posterior laryngitis with esomeprazole. Laryngoscope ; 116 : - Long MD, Shaheen NJ. Extra-esophageal GERD : clinical dilemma of epidemiology versus clinical practice. Curr Gastroenterol Rep ; 9 : - Flook N, Unge P, Agréus L, et al. Approach to managing undiagnosed chest pain : could gastroesophageal reflux disease be the cause? Can Fam Physician ; 53 : - 29
6 GERD - 30
7 GERD QUEST GERD GERD ph Carlsson R, Dent J, Bolling-Sternevald E, et al. The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease. Scand J Gastroenterol ; 33 : - Manterola C, Muñoz S, Grande L, et al. Initial validation of a questionnaire for detecting gastroesophageal reflux disease in epidemiological settings. J Clin Epidemiol ; 55 : - Wong WM, Lam KF, Lai KC, et al. A validated symptoms questionnaire (Chinese GERDQ) for the diagnosis of gastro-oesophageal reflux disease in the Chinese population. Aliment Pharmacol Ther ; 17 : - Zimmerman J. Validation of a brief inventory for diagnosis and monitoring of symptomatic gastro-oesophageal reflux. Scand J Gastroenterol ; 39 : - Kusano M, Shimoyama Y, Sugimoto S, et al. Development and evaluation of FSSG : frequency scale for the symptoms of GERD. J Gastroenterol ; 39 : - Shimoyama Y, Kusano M, Sugimoto S, et al. Diagnosis of gastroesophageal reflux disease using a new questionnaire. J Gastroenterol Hepatol ; 20 : - Kleinman L, Rothman M, Strauss R, et al. The infant gastroesophageal reflux questionnaire revised : development and validation as an evaluative instrument. Clin Gastroenterol Hepatol ; 4 : - GERD ; 62 : - 31
8 , GERD grade C D - NERD GERD grade CD 32
9 ph - Fennerty MB, Johnson DA. Heartburn severity does not predict disease severity in patients with erosive esophagitis. Med Gen Med ; 8 : Johnson DA, Fennerty MB. Heartburn severity underestimates erosive esophagitis severity in elderly patients with gastroesophageal reflux disease. Gastroenterology ; 126 : - Pilotto A, Franceschi M, Leandro G, et. al. Clinical features of reflux esophagitis in older people : a study of consecutive patients. J Am Geriatr Soc ; 54 : - El-Serag HB, Johanson JF. Risk factors for the severity of erosive esophagitis in Helicobacter pylori-negative patients with gastroesophageal reflux disease. Scand J Gastroenterol ; 37 : - Okamoto K, Iwakiri R, Mori M, et al. Clinical symptoms in endoscopic reflux esophagitis : evaluation in adult subjects. Dig Dis Sci ; 48 : - Locke GR, Zinsmeister AR, Talley NJ. Can symptoms predict endoscopic findings in GERD? Gastrointest Endosc. ; 58 : - Xiong LS, Chen MH, Lin JK, et al. Stratification and symptom characteristics of non-erosive reflux disease based on acid and duodenogastroesophageal reflux. J Gastroenterol Hepatol. ; 23 : - Tack J, Caenepeel P, Arts J, et al. Prevalence of acid reflux in functional dyspepsia and its association with symptom profile. Gut ; 54 : - Lin M, Gerson LB, Lascar R, et al. Features of gastroesophageal reflux disease in women. Am J Gastroenterol ; 99 : - Taghavi SA, Ghasedi M, Saberi-Firoozi M, et al. Symptom association probability and symptom sensitivity index : preferable but still suboptimal predictors of response to high dose omeprazole. Gut ; 54 : - Portale G, Peters J, Hsieh CC, et al. When are reflux episodes symptomatic? Dis Esophagus ; 20 : - Tefera L, Fein M, Ritter MP, et al. Can the combination of symptoms and endoscopy confirm the presence of gastroesophageal reflux disease? Am Surg ; 63 : - Noordzij JP, Khidr A, Desper E, et al. Correlation of ph probe-measured laryngopharyngeal reflux with symptoms and signs of reflux laryngitis. Laryngoscope ; 112 : - 33
10 PPI GERD ph GERD mg/ NERD GERD mg/ GERD non-cardiac chest painnccp, 34
11 Johnsson F, Weywadt L, Solhaug JH, et al. One-week omeprazole treatment in the diagnosis of gastro-oeophageal reflux disease. Scand J Gastroenterol ; 33 : - Schenk BE, Kuipers EJ, Klinkenberg-Knol EC, et al. Omeprazole as a diagnostic tool in gastroesophageal reflux disease. Am J Gastroenterol ; 92 : - Fass R, Fennerty MB, Ofman JJ, et al. The clinical and economic value of a short course of omeprazole in patients with noncardiac chest pain. Gastroenterology ; 115 : - Field SK, Sutherland LR. Does medical antireflux therapy improve asthma in asthmatics with gastroesophageal reflux? : a critical review of the literature. Chest ; 114 : - Kamel PL, Hanson D, Kahrilas PJ. Omeprazole for the treatment of posterior laryngitis. Am J Med ; 96 : - Wo JM, Grist WJ, Gussack G, et al. Empiric trial of high-dose omeprazole in patients with posterior laryngitis. Am J Gastroenterol ; 92 : - 35
12 mucosal break mm grade A mm grade B grade C grade D grade ph grading 36
13 Savary-Miller Hetzel-Dent grade Nminimal change grade M grade N A, mucosal break minimal change minimal change Armstrong D, Bennett JR, Blum AL, et al. The endscopic assessment of esophagitis : a progress report on observer agreement. Gastroenterology ; 111 : - Savary M, Miller G. The Esophagus Handbook and Atlas of Endoscopy. By Sassmann AG, Solothurn, Swizterland, Lundell LR, Dent J, Bennett JR, et al. Endoscopic assessment of oesophagitis : clinical and functional correlates and further validation of the Los Angeles classification. Gut ; 45 : - Kusano M, Sugimoto S, Kawamura O, et al. Numerical modification of the Los Angeles classification of gastroesophageal reflux disease fails to decrease observer variation. Dig Endosc ; 16 : - Kusano M, Ino K, Yamada T, et al. Interobserver and intraobserver variation in endoscopic assessment of GERD using the Los Angeles classification. Gastrointest Endosco ; 49 : - Rath HC, Timmer A, Kunkel C, et al. Comparison of interobserver agreement for different scoring systems for reflux esophagitis : impact of level of experience. Gastrointest Endosc ; 60 : - Pandolfino JE, Vakil NB, Kahrilas PJ. Comparison of inter- and intraobserver consistency for grading of esophagitis by expert and trainee endoscopists. Gastrointest Endosc ; 56 : - Hoshihara Y. Endoscopic findings of GERD. Nippon Rinsho ; 62 : 37
14 ph GERD ph symptom indexsi symptom sensitivity indexssi symptom association probabilitysap GERD ph GERD ph 38
15 ph - Pace F, Santalucia F, Bianchi Porro G. Natural history of gastro-oesophageal reflux disease without oesophagitis. Gut ; 32 : - Trimble KC, Douglas S, Pryde A, et al. Clinical characteristics and natural history of symptomatic but not excess gastroesophageal reflux. Dig Dis Sci ; 40 : - Wiener GJ, Richter JE, Copper JB, et al. The symptom index : a clinically important parameter of ambulatory -hour esophageal ph monitoring. Am J Gastroenterol ; 83 : - Breumelhof R, Smout AJ. The symptom sensitivity index : a valuable additional parameter in -hour esophagal ph recording. Am J Gastroenterol ; 86 : - Weusten BL, Roelofs JM, Akkermans LM, et al. The symptom-association probability : an improved method for symptom analysis of -hour esophageal ph data. Gastroenterology ; 107 : - Wiener GJ, Morgan TM, Copper JB, et al. Ambulatory -hour esophageal ph monitoring. Reproducibility and variability of ph parameters. Dig Dis Sci ; 33 : - Klinkenberg-Knol EC, Meuwissen SG. Combined gastric and oesophageal -hour ph monitoring and oesophageal manometry in patients with reflux disease, resistant to treatment with omeprazole. Aliment Pharmacol Ther ; 4 : - Wong WM, Bautista J, Dekel R, et al. Feasibility and tolerability of transnasal/per-oral placement of the wireless ph capsule vs. traditional -h oesophageal ph monitoring--a randomized trial. Aliment Pharmacol Ther ; 21 : - des Varannes SB, Mion F, Ducrotté P, et al. Simultaneous recordings of oesophageal acid exposure with conventional ph monitoring and a wireless system (Bravo). Gut ; 54 : - Prakash C, Clouse RE. Value of extended recording time with wireless ph monitoring in evaluating gastroesophageal reflux disease. Clin Gastroenterol Hepatol ; 3 : - 39
16 Barrett Barrett Neaf Savary columnar-lined lower esophagus American College of Gastroenterology Barrett Barrett Interna- 40
17 tional Working Group for the Classification of the OesophagitisIWGCO Barrett CM, Barrett Barrett Barrett, Barrett squamocolumnar junctionscjesophago-gastric junctionegj SCJ specialized columnar epitheliumsce - Barrett Naef AP, Savary M, Ozzello L, et al. Collumnar-lined lower esophagus : an acquired lesion with malignant predisposition. J Thorac Cardiovasc Surg ; 70 : - Sampliner. Practice guidelines on the diagnosis, surveillance, and therapy of Barrett s esophagus. Am J Gastroenterol ; 93 : - Armstrong D. Review article : towards consistency in the endoscopic diagnosis of Barrett s oesophagus and columnar metaplasia. Aliment Pharmacol Ther ; 20 (Suppl ) : - Sharma P, Dent J, Armstrong D, et al. The development and validation of an endoscopic grading system for Barrett s esophagus : The prague C & M criteria. Gastroenterology ; 131 : - p- Hameeteman W, Tytgat GN, Houthoff HJ, et al. Barrett s esophagus : development of dysplasia and adenocarcinoma. Gastroenterology ; 96 : - Cameron AJ, Lomboy CT, Pera M, et al. Adenocarcinoma of the esophagogastric junction and Barrett s esophagus. Gastroenterology ; 109 : - Jass JR. Role of intestinal metaplasia in the histogenesis of gastric carcinoma. J Clin Pathol ; 33 : - Spechler SJ, Zeroogian JM, Antonioli DA, et al. Prevalence of metaplasia at the gastroesophageal junction. Lancet ; 344 : - Montgomery E, Bronner MP, Goldblum JR, et al. Reproducibility of the diagnosis of dyspla- 41
18 sia in Barrett esophagus : a reaffirmation. Hum Pathol ; 32 : - Meining A, Ott R, Becker I, et al. The Munich Barrett follow up study : suspicion of Barrett s oesophagus based on either endoscopy or histology only-what is the clinical significance? Gut ; 53 : - Kim SL, Waring JP, Spechler SJ, et al. Diagnostic inconsistencies in Barrett s esophagus. Gastroenterology ; 107 : - Alikhan M, Rex D, Khan A, et al. Variable pathologic interpretation of columnar lined esophagus by general pathologists in community practice. Gastrointest Endosc ; 50 : - 42
慢性膵炎GL-01.qxd
12 GERD GERD RCT CQ Delphi Fass R, Shapiro M, Dekel R, et al. Systematic review : proton-pump inhibitor failure in gastrooesophageal reflux disease--where next? Aliment Parmacol Ther ; 22 : - Lundell LR,
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