090825_Sakate_for_dist.pptx
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1 21 子 比 Evola 用 手龍一 月 25 日 火 心
2 H-InvDBEvola
3 子 子 子 子 子
4 日 比 Evola 用 比 子 Evola 方
5 比 子
6 Evola 子 H-InvDB 6 子
7 比 子 生 子
8 生 生 片 方
9 比 長 大 子 生 長 生
10 22,496 子 13 生 長 魚
11 比
12 子 子 生 子 子 生 子 生 子
13 子 子 子 子
14 Neighbor-Joining, NJ 子 生 一 子 生 900/1000 長 - 歯 - 足 一 子 子
15 Evola 方
16 Evola 子 子
17 Evola 面
18 Keyword 子 (Definition) lung cancer Gene symbol HUGO 子 ID RHEB Accession number 生 H-Inv transcript ID (HIT) HIT H-Inv cluster ID (HIX) HIX DDBJ AB Ensembl ENSPTRT RefSeq NM_173392
19
20
21
22 示
23 比
24 子 比
25 HUGO
26 文 Evola: Ortholog database of all human genes in H-InvDB with manual curation of phylogenetic trees. Matsuya A, Sakate R, Kawahara Y, et al. Nucleic Acids Res. D (2008) A web tool for comparative genomics: G-compass. Fujii Y, Itoh T, Sakate R, et al. Gene 364, (2005) G-compass: A web-based comparative genome browser between human and other vertebrate genomes. Kawahara Y, Sakate R, Matsuya A, et al. Submitted
27
28 子 高 子 子
29 生 BMP4/CHRD 子 子 子 子
30 子 子
31 子 HBE1 HBG1 HBB HBM HBZ HBA1,2 HBQ1
32 子 CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis. Nishiyama M, Oshikawa K, Tsukada Y, Nakagawa T, Iemura S, Natsume T, Fan Y, Kikuchi A, Skoultchi AI, Nakayama KI. Nat Cell Biol Feb;11(2): Epub 2009 Jan 18. Identification of a BK channel auxiliary protein controlling molecular and behavioral tolerance to alcohol. Martin GE, Hendrickson LM, Penta KL, Friesen RM, Pietrzykowski AZ, Tapper AR, Treistman SN. Proc Natl Acad Sci U S A Nov 11;105(45): Epub 2008 Nov 3. The transcriptional repressor DEC2 regulates sleep length in mammals. He Y, Jones CR, Fujiki N, Xu Y, Guo B, Holder JL Jr, Rossner MJ, Nishino S, Fu YH. Science Aug 14;325(5942): DEC2 Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/ threonine phosphatase to activate ASK1. Takeda K, Komuro Y, Hayakawa T, Oguchi H, Ishida Y, Murakami S, Noguchi T, Kinoshita H, Sekine Y, Iemura S, Natsume T, Ichijo H. Proc Natl Acad Sci U S A Jul 28;106(30): Epub 2009 Jul 9. Mitochondrial phosphoglycerate mutase 5 = PGAM5 ASK1 MAP3K5MAP3K5
スライド 1
平成 23 年度第 2 回データベース講習会 創薬研究における統合データベースの活用 比較ゲノムデータベース Evola, G-compass の活用法 http://hinv.jp/evola/ http://hinv.jp/g-compass/ 産業技術総合研究所バイオメディシナル情報研究センター 原雄一郎 2012 年 1 月 20 日 ( 金 ) 於 : 産業技術総合研究所関西センター 本日の概要
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