BRC 61

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かずきわくや
4 years ago
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1 BRC 61

2 JF1 F1 LDH 62

3 (Macaca fascicularis) DBA/2 ddy BDF1 C57BL/6 B6 TG BDF1 C57BL/6 Publications 1.Itoh M., Matsuda J., Suzuki O., Ogura A., Oshima A., Tai T., Suzuki Y. and Takashima S.: "Development of lysosomal storage in mice with targeted disruption of the betagalactosidase gene: a model of human GM1-gangliosidosis", Brain Dev. 23, (2001).* 63

4 2.Nakada K., Inoue K., Chen C. S., Nonaka I., Goto Y., Ogura A. and Hayashi J. I.: "Correlation of functional and ultrastructural abnormalities of mitochondria in mouse heart carrying a pathogenic mutant mtdna with a 4696-bp deletion", Biochem. Biophys. Res. Commun. 288, (2001).* 3.Nakada K., Inoue K., Ono T., Isobe K., Ogura A., Goto Y., Nonaka I. and Hayashi J. I.: "Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtdna", Nat. Med. 7, (2001).* 4.Ogonuki N., Sankai T., Yagami K., Shikano T., Oda S., Miyazaki S. and Ogura A.: "Activity of a sperm-borne oocyte-activating factor in spermatozoa and spermatogenic cells from cynomolgus monkeys and its localization after oocyte activation", Biol. Reprod. 65, (2001).* 5.Ogura A., Ogonuki N., Takano K. and Inoue K.: "Microinsemination, nuclear transfer and cytoplasmic transfer: the application of new reproductive engineering techniques to mouse genetics", Mammalian Genome 12, (2001)* 6.Ohba Y., Ikuta K., Ogura A., Matsuda J., Mochizuki N., Nagashima K., Kurokawa K., Mayer B.J., Maki K., Miyazaki J. and Matsuda M.: "Requirement of C3G-dependent Rap1 activation for cell adhesion and embryogenesis", EMBO J. 20, (2001).* 7.Yamaguchi M., Manabe N., Uchio-Yamada K., Akashi N., Yamamoto Y., Ogura A. and Miyamoto H.: "Localization of proliferative and apoptotic cells in the kidneys of ICRderived glomerulonephritis (ICGN) mice ", J. Vet. Med. Sci. 63, (2001).* 8.Kobayashi S., Kohda T., Ichikawa H., Ogura A., Ohki M., Kaneko-Ishino T. and Ishino F.: "Paternal Expression of a Novel Imprinted Gene, Peg12/Frat3, in the mouse 7C Region Homologous to the Prader-Willi Syndrome Region", Biochem. Biophys. Res. Commun. 290, (2002).* 9.Kanatsu-Shinohara M., Ogura A., Ikegawa M., Inoue K., Ogonuki N., Tashiro K., Toyokuni S., Honjo T. and Shinohara T.: "Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice", Proc. Natl. Acad. Sci. USA 99, (2002).* 10.Inoue K., Kohda T., Lee J., Ogonuki N., Mochida K., Noguchi Y., Tanemura K., 64

5 Kaneko-Ishino T., Ishino F. and Ogura A.: "Faithful expression of imprinted genes in cloned mice", Science 295, 297 (2002).* 11.Ogonuki N., Inoue K., Yamamoto Y., Noguchi Y., Tanemura K., Suzuki O., Nakayama H., Doi K., Ohtomo K., Satoh M., Nshida A. and Ogura A.: "Early death of mice cloned from somatic cells", Nat. Genet. 30, (2002).* 1.Mochida K., Matsuda J., Suzuki O., Nakahira M., Noguchi A., Nakayama K., Kurosawa S., Takano K., Noguchi Y., Yamamoto Y. and Ogura A.: Development of reproductive biotechniques in mastomys. In: Reproductive Biotechnology, edited by Miyamoto H. and Manabe N. Hokuto Shobo, Kyoto, (2001). 2.Ogura A., Inoue K., Mochida K., Ogonuki N. and Yanagimachi R.: "Fertilization without spermatozoa", Ital. J. Anat. Embryol. 106, 3-10 (2001). Oral Presentations 1.Inoue K., Ogonuki N., Ishino F., and Ogura A.: Cloning mice with fetal and adult fibroblast cells and analysis of Igf2 and Igf2r expression in their term placentae, 34 th Ann. Meet. of Society for the Study of Reproduction, Ottawa, Canada, Aug. (2002). 2.Ogura A.: Phenotypes and epigenetic status of mice cloned from somatic cells, Int. Sympo. Development and Epigenetics of Mammalian Germ cells and Pluripotent Stem cells, Kyoto, Japan, Nov. (2001). 3.Ogonuki N., Tsuchiya H., Hirose Y., Okada H., Ogura A., and Sankai T.: Pregnancy 65

6 following round spermatid injection in the cynomolgus monkey, Int. Sympo. Development and Epigenetics of Mammalian Germ cells and Pluripotent Stem cells, Kyoto, Japan, Nov. (2001). 4.Inoue K., Ogouniki N., Mochida K., Yamamoto Y., Kohda T., Ishino F. and Ogura A.: Effects of donor cell type and genotype on the efficiency of somatic cloning in the mouse, Int. Sympo. Development and Epigenetics of Mammalian Germ cells and Pluripotent Stem cells, Kyoto, Japan, Nov. (2001). 66

7 Olygonucleotide array 67

8 図1 図2 68

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表1.eps

表1.eps Vol.1 C ontents 1 2 cell-free EMBO J Proc. Natl. Acad. Sci. USA NatureEMBO J 3 RNA NatureEMBO J Nature EMBO J 4 5 HCV HCV HCV HCV RNA HCV in situ 6 7 8 Nat Struct Mol Biol J Biol Chem Nat Commun J Virol