本文/AY380M

Size: px
Start display at page:

Download "本文/AY380M"

Transcription

1 tmrna tmrna RNA mrna turnover RNase class I peptide release factor RF ribosome rescue trna mrna transfer-messenger RNA tmrna RNA tmrna SmpB trna transtranslation C tmrna mrna ATP tmrna tmrna tmrna-independent ribosome rescue systems in bacteria and mitochondria Nobukazu Nameki Division of Molecular Science, Faculty of Science and Technology, Gunma University, Tenjincho, Kiryu-shi, Gunma, Japan tmrna tmrna SmpB tmrna ssra mrna tmrna tmrna YaeJ ArfA YaeJ RF trna PTH GGQ Gly-Gly-Gln YaeJ tmrna YaeJ ICT DNA mtdna tmrna SmpB ICT GGQ Corf tmrna GGQ pp.

2 ICTYaeJ Corf ICT NMR RF β β RF π-hb turnict α-helix αi ICT RF ICTYaeJ PTH ICTYaeJ RF ICT ICT RF RF erf GGQ RF RF A ICT YaeJ N RF Corf ICT RF β βrf π-hb turn Corf ICT ICT GGQ GGQ YaeJ YaeJ GGQ YaeJ YaeJ PTH PUREsystem mrna crp nonstop mrna Lys SDS YaeJ trna YaeJ trna Crp Anonstop mrna YaeJ PTH Arg mrna YaeJ PTH tmrna mrna YaeJ YaeJ YaeJ S C YaeJ C in vitro YaeJ tmrna ArfA suppress yaej YaeJ tmrna YaeJ PTH codon-independent RF cirf tmrna YaeJ tmrna mrna A tmrna A mrna YaeJ A mrna tmrna

3 GGQ A GGQ GGQ GGQ αi α-helix BGGQ α β α-helix β-strand -helix C CorfPDB code RSM ICTJ mrna YaeJ mrna RNase mrna A-site cleavagetmrna SmpB YaeJ Steitz YaeJ Thermus thermophilus

4 YaeJ ICT Corf A SDS YaeJ PTH B RNAi ICT Corf si-nt non-targeting duplex sirnas C ICT Corf MitoTracker Red CMXRos MitoTracker Green FM Flow cytometry RF P trna trna YaeJ C α-helix mrna entry channels mrna α-helix flexible linker α-helix S SmpB YaeJ C tmrna SmpB A C α-helix mrna entry channel YaeJ SmpB YaeJ S RNA G syn anti mrna A YaeJ mrna entry channel mrna YaeJ C YaeJ T. thermophilus ICT ICTHT-D immature colon carcinoma cell transcript ICT Chrzanowska-Lightowlers ICT

5 ICT sirna ICT mtdna S ICT PTH nonstop mrna ICT ICT mtdna Corf tmrna SmpB ICT ICT GGQ Corf corf nonsense Corf corf nonsense Shoubridge ICT ICT c COX Corf ICT ICT S nonstop mrna PTH PTH PTH ICT Corf Flow cytometry ICTCorf RNAi ICT Corf B Corf ICT C ICT Corf ICT Corf GGQ YaeJ ArfA yhdl ArfA ArfA tmrna ArfA mrna C RNase III nonstop mrna tmrna SmpB ArfA C tmrna SmpB tmrna ArfA ArfA ArfA tmrna YaeJ ArfA GGQ PTH

6 RF ArfA trna ArfA RF tmrna SmpB ArfA NeisserialesEnterobacteriales YaeJ ICT Corf tmrna Moore, S.D. & Sauer, R.T.Annu. Rev. Biochem.,,. Hayes, C.S. & Keiler, K.C.FEBS Lett.,,. Janssen, B.D. & Hayes, C.S. Adv. Protein Chem. Struct. Biol.,,. Handa, Y., Inaho, N., & Nameki, N.Nucleic Acids Res.,,. Handa, Y., Hikawa, Y., Tochio, N., Kogure, H., Inoue, M., Koshiba, S., Güntert, P., Inoue, Y., Kigawa, T., Yokoyama, S., & Nameki, N.J. Mol. Biol.,,. Kogure, H., Hikawa, Y., Hagihara, M., Tochio, N., Koshiba, S., Inoue, Y., Güntert, P., Kigawa, T., Yokoyama, S., & Nameki, N.Proteins,,. Chadani, Y., Ono, K., Kutsukake, K., & Abo, T.Mol. Microbiol.,,. Asano, K., Kurita, D., Takada, K., Konno, T., Muto, A., & Himeno, H.Nucleic Acids Res.,,. Ivanova, N., Pavlov, M.Y., Felden, B., & Ehrenberg, M. J. Mol. Biol.,,. Shimizu, Y.J. Mol. Biol.,,. Sunohara, T., Jojima, K., Tagami, H., Inada, T., & Aiba, H. J. Biol. Chem.,,. Hayes, C.S. & Sauer, R.T.Mol. Cell,,. Gagnon, M.G., Seetharaman, S.V., Bulkley, D., & Steitz, T.A. Science,,. Kurita, D., Muto, A., & Himeno, H.J. Nucleic Acids,,. Neubauer, C., Gillet, R., Kelley, A.C., & Ramakrishnan, V. Science,,. van Belzen, N., Diesveld, M.P., van der Made, A.C., Nozawa, Y., Dinjens, W.N., Vlietstra, R., Trapman, J., & Bosman, F.T. Eur. J. Biochem.,,. Richter, R., Rorbach, J., Pajak, A., Smith, P.M., Wessels, H.J., Huynen, M.A., Smeitink, J.A., Lightowlers, R.N., & Chrzanowska-Lightowlers, Z.M.EMBO J.,,. Antonicka, H., Ostergaard, E., Sasarman, F., Weraarpachai, W., Wibrand, F., Pedersen, A.M., Rodenburg, R.J., van der Knaap, M.S., Smeitink, J.A., Chrzanowska-Lightowlers, Z.M., & Shoubridge, E.A.Am.J.Hum.Genet.,,. Shimazaki, H., Takiyama, Y., Ishiura, H., Sakai, C., Matsushima, Y., Hatakeyama, H., Honda, J., Sakoe, K., Naoi, T., Namekawa, M., Fukuda, Y., Takahashi, Y., Goto, J., Tsuji, S., Goto, Y., Nakano, I., & Japan Spastic Paraplegia Research, C. J. Med. Genet.,,. Chadani, Y., Ono, K., Ozawa, S., Takahashi, Y., Takai, K., Nanamiya, H., Tozawa, Y., Kutsukake, K., & Abo, T. Mol. Microbiol.,,. Garza-Sanchez, F., Schaub, R.E., Janssen, B.D., & Hayes, C.S. Mol. Microbiol.,,. Chadani, Y., Ito, K., Kutsukake, K., & Abo, T.Mol. Microbiol.,,.

本文/YA2007C

本文/YA2007C pp.! mrna trna RNA tmrna mrna RNA trna mrna tmrna tmrna tmrna Ray Molecular mechanism of trans-translation Hyouta Himeno, Daisuke Kurita, Kazuma Takada, Takayuki Konno, Kyoko Hanawa-Suetsugu, Chie Takemoto,

More information

会報35号表紙.pdf

会報35号表紙.pdf 35 No. (2017 1 ) RNA 2017 2017 TV 365 365 chunky 26 RNA 2017 Congratulations26 30-1 - RNA 2017-2 - - 3 - - 4 - - 5 - - 6 - 2016 8 31 9 2 RNA 2016 1 RNA RNA RNA RNA RNA 1-7 - RNA RNA 3 3 7 31 RNA ncrna

More information

表1.eps

表1.eps Vol.1 C ontents 1 2 cell-free EMBO J Proc. Natl. Acad. Sci. USA NatureEMBO J 3 RNA NatureEMBO J Nature EMBO J 4 5 HCV HCV HCV HCV RNA HCV in situ 6 7 8 Nat Struct Mol Biol J Biol Chem Nat Commun J Virol

More information

本文/YA4278I

本文/YA4278I pp. D- D-DAO DAO D- D- D- D- o- DAO-D- D-DAO DAO Hans Krebs FAD X DAO DAO DAO D- Structure and reaction mechanism of D-amino acid oxidase Yasuzo Nishina School of Health Sciences, Kumamoto University,

More information

Minamiooya, Machida, Tokyo 194, Japan] RNA World, A Key Step in the Origin of Life : Inspection from the View Point of Biological Evolution 1) Crick, F. H. C.: Sym. Soc. Exp. Biol., 12, 548-555

More information

本文/AY380L

本文/AY380L RNA- RNA RNA Nanotechnology & Therapeutics Lexington RNA Salt Lake City FNANO FNANO RNA RNA RNA- RNP RNA DNA DNA DNA RNA RNA ips CiRA RNA-Protein nanotechnology & synthetic biology Hirohide Saito The Hakubi

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service SMN (Survival

More information

その科学と技術 No.48( )

その科学と技術 No.48( ) 45 CI +,,* a-, +0 a-, +0 a-, +., a-, + +, - +, CD CF - CTS CD a-cd b-cd g-cd a- +., 0 1 2 - +33-. CI CI CD CD a- +., CI a- +0, CD Bacillus circulans T--*.*. 13 a-, +0 CI-1 CI-2. CI-3 +* / CI 0 CI-1 CI-+1

More information

The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Database Center for Life Science Online Service Key words Shigey

The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Database Center for Life Science Online Service Key words Shigey The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Key words Shigeyuki Kawai, Chikako Fukuda, Kousaku Murata E-mail : kawais@kais.kyoto-u.ac.jp, chikakko@kais.kyotou.ac.jp,

More information

会報36号表紙

会報36号表紙 36 No. ( 2017 9 ) RNA 2017 RNA 19 7 19 21 7 8 JR RNA RNA 20 RNA RNA RNA RNA 10 50 13 26% 40 RNA RNA-SEQRNAiCRISPRCLIP RNA RNA - 1 - 3 29 8-2 - ips - 3 - - 4 - - 5 - RNA 29 RNA RNA 5 microrna trna? RNA

More information

1 911 9001030 9:00 A B C D E F G H I J K L M 1A0900 1B0900 1C0900 1D0900 1E0900 1F0900 1G0900 1H0900 1I0900 1J0900 1K0900 1L0900 1M0900 9:15 1A0915 1B0915 1C0915 1D0915 1E0915 1F0915 1G0915 1H0915 1I0915

More information

tary adenylate cyclase activating polypeptide ; PA-

tary adenylate cyclase activating polypeptide ; PA- Conformation of a peptide ligand bound to its G-protein coupled receptor and its implication for ligand transportation tary adenylate cyclase activating polypeptide ; PA- molecular biology (ed. Rich,

More information

Database Center for Life Science Online Service Discovery, analysis and chemical mechanism of protein splicing

Database Center for Life Science Online Service Discovery, analysis and chemical mechanism of protein splicing Discovery, analysis and chemical mechanism of protein splicing VMA1 VMA1 2) Anraku, Y.: Genes to Cells, 2, 359-367 (1997) 3) Perler, F. B.: Cell, 92,1-4 (1998) 4) Perler, F. B.: Trends Biochem.

More information

本文/YA4096E

本文/YA4096E Montiel, M.D., Krzewinski-Recchi, M.A., Delannoy, P., & Harduin-Lepers, A.Biochem. J.,,. Nagata, Y., Yamashiro, S., Yodoi, J., Lloyd, K.O., Shiku, H., & Furukawa, K.J. Biol. Chem.,,. Dohi, T., Nishikawa,

More information

Bio-No.57/3....

Bio-No.57/3.... 2004. MAR. 3No.57 http://www.wako-chem.co.jp C O N T E N T S 2 Wako Bio Window No.57 MAR.2004 l l l l wako wako l l mmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmm Wako Bio Window No.57 MAR.2004 3 4 Wako Bio Window

More information

46 12 3 1 ATP ( ) ATP ~P 1~P hyd Gº 1 1 1950 ~P hyd Gº Hansia et al. Biophys Chem 119: 127, 2006 ~P hyd Gº 1? ATP hyd Gº ATP ATP ATP ~P ε ~P George [BBA 223: 1, 1970] ~P 2) hyd Gº 1. ph Mg 2+ 2. 1 2 2

More information

たんぱく3000web.indd

たんぱく3000web.indd 1 2 4 5 3000 6 8 3000 10 10 11 11 12 12 13 13 14 18 19 20 21 Atg 22 23 24 21 X 143000 3000 19 3000 20 25 X 26 27 28 1 20 DNA mrna DNA RNA mrna 3000 DNAmRNARNA SPring-8X Artsimovitch, I. et al., Cell 117,

More information

本文/YA7261E

本文/YA7261E J. Cell Biol.,,. Segev, N.Curr. Opin. Cell Biol.,,. Lafont, F., Lecat, S., Verkade, P., & Simons, K.J. Cell Biol.,,. Mostov, K.E., Verges, M., & Altschuler, Y.Curr. Opin. Cell Biol.,,. Sato, T., Mushiake,

More information

:010_ :3/24/2005 3:27 PM :05/03/28 14:39

:010_ :3/24/2005 3:27 PM :05/03/28 14:39 :010_896300101703 :3/24/2005 3:27 PM :05/03/28 14:39 :010_896300101703 :3/24/2005 3:27 PM :05/03/28 14:39 :010_896300101703 :3/24/2005 3:27 PM :05/03/28 14:39 :010_896300101703 :3/24/2005 3:27 PM :05/03/28

More information

弘前大学農学生命科学部学術報告

弘前大学農学生命科学部学術報告 Dictyostelium FEMS Microbiol Dictyostelium Mechanisms of Development FEMS Microbiol. Lett Corvus corone orientalis. Jpn. J. Ornithol Asterina pectinifera. Zoological Science Asthenosoma ijimai Dictyostelium

More information

1...z04/08/.e2

1...z04/08/.e2 August 2004 29 α α 30 Functional Glycomics News Letter No.4 α α August, 2004 31 β ü β α β α 32 Functional Glycomics News Letter No.4 α β August, 2004 33 34 Functional Glycomics News Letter No.4 α β ü August,

More information

< > Introduction to Basic Physical Chemistry 1,2 2 [ advanced [ [ [ [ [ KULASIS

< > Introduction to Basic Physical Chemistry 1,2 2 [ advanced [ [ [ [ [ KULASIS < > Introduction to Basic Organic Chemistry 1,2 [ 2 [ 10 11 12 13 14 15 [ [ [ [ KULASIS < > Introduction to Basic Physical Chemistry 1,2 2 [ advanced [ 11 12 14 15 [ [ [ [ KULASIS < > Introduction to Basic

More information

1) Murphy, T.H., Miyamoto, M., Sastre, A., Schnaar, R.L., Coyle, J.T.: Neuron, 2, 1547-1558 (1989) 2) Pellegrini-Giampietro, D.E., Cherici, G., Ale siani,m., Carla, V., Moroni, F.: J. Neuro science,10,

More information

タンパク質を物性科学的に見た場合、単なるアミド結合の集合体であると片づけるにはもったいなさすぎる

タンパク質を物性科学的に見た場合、単なるアミド結合の集合体であると片づけるにはもったいなさすぎる Precise Functional Analysis of Biological Macromolecules Promoted by the Encounter of Crystallographic and Spectroscopic Molecular Structure Analyses Takamitsu Kohzuma*, Sachiko Yanagisawa, and Tomotake

More information

…h…L…–…†…fi…g1

…h…L…–…†…fi…g1 21 1326 1328 2002 22 4375 4377 2003 34 6 848 849 2005 9 10 15 1067 1070 1996 49 133 166 2003 1 2 2 3 4 4 1 3 23 311 313 2004 5 1 118 7604 7607 1996 15 1 33 6627 6629 2000 12 649 155 167 2003 76 23 7007

More information

Various function and toxicity of iron Key words 1) Hentze, M. W. et al: Cell, 117, 285-297 (2004) 2) Ganz, T.: Blood, 102, 783-788 (2003) 3) Nemeth, E. et al.: Science, 306, 2090-2093 (2004) 4) Hentze,

More information

本文/YA1174C

本文/YA1174C RecF DNA RecA DNA RecA RecF Steve Kowalczykowski Susan Lovett RecJ Mimitou, E.P. & Symington, L.S.Nature,,. Zhu, Z., Chung, W.H., Shim, E.Y., Lee, S.E., & Ira, G. Cell,,. Gravel, S., Chapman, J.R., Magill,

More information

Database Center for Life Science Online Service Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sap

Database Center for Life Science Online Service Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sap Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060, Japan] Molecular Basis of Triplet Repeat Diseases : Genetic Instabillity and Unusual DNA

More information

1) van Meer, G., Op den Kamp, J. A.: J. Cell. Biochem., 19, 193-2040982) 2) Gaffet, P., Bettache, N., Bienvenue, A.: Biochemistry, 34, 6762-6769(1995) 3) Sims, P. J., Wiedmer, T.: Thromb. Haemost., 86,

More information

2007 Vol.56 No.6 総説 丸山浩樹

2007 Vol.56 No.6 総説 丸山浩樹 Reprinted from RADIOISOTOPES, Vol.56,.6 June 2007 Japan Radioisotope Association http : //www.jrias.or.jp/ α β α β ε m z α µ µ α m z m z µ µ Curr. Opin. Biotechnol J. Proteome Res Rapid Commun. Mass

More information

) a + b = i + 6 b c = 6i j ) a = 0 b = c = 0 ) â = i + j 0 ˆb = 4) a b = b c = j + ) cos α = cos β = 6) a ˆb = b ĉ = 0 7) a b = 6i j b c = i + 6j + 8)

) a + b = i + 6 b c = 6i j ) a = 0 b = c = 0 ) â = i + j 0 ˆb = 4) a b = b c = j + ) cos α = cos β = 6) a ˆb = b ĉ = 0 7) a b = 6i j b c = i + 6j + 8) 4 4 ) a + b = i + 6 b c = 6i j ) a = 0 b = c = 0 ) â = i + j 0 ˆb = 4) a b = b c = j + ) cos α = cos β = 6) a ˆb = b ĉ = 0 7) a b = 6i j b c = i + 6j + 8) a b a b = 6i j 4 b c b c 9) a b = 4 a b) c = 7

More information

本文/YA9255C

本文/YA9255C pp. E- -SH X in vitro in vivo -SH Structure-based drug development and medical biological application of cathepsin specific inhibitors Nobuhiko Katunuma Institute for Health Sciences, Tokushima Bunri University,Nishihamabouji,

More information

Kazumitsu Ueda, [Department of Applied Life Science, Kyoto University Graduate School of Agriculture, Kitashirakawa, Sakyo-ku, Kyoto 606-01, Japan] Molecular Mechanisms for Drug Transport by MDR1/P-glycoprotein

More information

研究成果報告書(基金分)

研究成果報告書(基金分) GCP(Golgi cytoplasmic protein) coiled-coil golgin GCP golgin golgin golgin golgin p115 golgin-84 COG 1,6 G, SNAREs, ER- p115 BBRC 2005,6 golgin giantin, golgin-84, CASP, p115 COPI golgin G SNAREs golgin-84

More information

Vol.40 No.5△/△0 目次[三]10.23

Vol.40 No.5△/△0 目次[三]10.23 ! Department of Management, Miyagi University, 2 2 1 Hatatate Taihaku-ku Sendai, Miyagi 982 0215 Industrial Technology Institute, Miyagi Prefectural Government, 2 2 Akedoori Izumi-ku Sendai, Miyagi 981

More information

(2) (2) (3) (3) (4) ABI PRISM 7700 TaqMan (4) Roche LightCycler TM (5) BioFlux LineGene TaqMan (6) 1 RT-PCR (7) (9) (10) F. Hoffmann-La Roche Ltd. Roc

(2) (2) (3) (3) (4) ABI PRISM 7700 TaqMan (4) Roche LightCycler TM (5) BioFlux LineGene TaqMan (6) 1 RT-PCR (7) (9) (10) F. Hoffmann-La Roche Ltd. Roc 05-8 Realtime PCR Master Mix (Code No. QPK-101, QPK-101T) TOYOBO CO., LTD. Life Science Department OSAKA JAPAN A3313K (2) (2) (3) (3) (4) ABI PRISM 7700 TaqMan (4) Roche LightCycler TM (5) BioFlux LineGene

More information

研修コーナー

研修コーナー l l l l l l l l l l l α α β l µ l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l

More information

1_alignment.ppt

1_alignment.ppt " " " " n " n n " n " n n n " n n n n " n LGPSSKQTGKGW-SRIWDN! + +! LN-ITKSAGKGAIMRLGDA! " n -------TGKG--------!! -------AGKG--------! " n w w w " n w w " " " 11 12 " n w w w " n w w A! M! O! A!

More information

 生体内に存在する蛋白質の中には、20種類の基本アミノ酸だけでは機能の発現ができない蛋白質が存在する

 生体内に存在する蛋白質の中には、20種類の基本アミノ酸だけでは機能の発現ができない蛋白質が存在する 21 Vol.11 No.1 Linda Rasubala Centre National de la Recherche Scientifique Dominique Fourmy Molecular Basis for the selenocysteine incorporation Toyoyuki Ose 1, Linda Rasubala 1, Satoko Yoshizawa 2, Dominique

More information

36 th IChO : - 3 ( ) , G O O D L U C K final 1

36 th IChO : - 3 ( ) , G O O D L U C K final 1 36 th ICh - - 5 - - : - 3 ( ) - 169 - -, - - - - - - - G D L U C K final 1 1 1.01 2 e 4.00 3 Li 6.94 4 Be 9.01 5 B 10.81 6 C 12.01 7 N 14.01 8 16.00 9 F 19.00 10 Ne 20.18 11 Na 22.99 12 Mg 24.31 Periodic

More information

Florigen in rice Key words Shojiro Tamaki, Ko Shimamoto E-mail : s-tamaki@bs.naist.jp, simamoto@bs.naist.jp URL : http://bsw3.naist.jp/simamoto/simaoto.html 1) Thomas, B., Vince-prue, D.: Photoperiodism

More information

10中西_他.indd

10中西_他.indd Streptomyces mobaraensis N N N Sm b Sm N N Sm Sm Sm ' ' Sm Sm ak K k K bk k K Sm Sm a b S. mobaraensis a b a b Sm b b bb b b Sm Sm S. lividans ab Sm ab Sm ab ab ab ab SmSm S. lividansab S. lividans ab

More information

(2009) 1... / 1 ( ) / 1 ( ) / 1 ( ), 2 ( )

(2009) 1... / 1 ( ) / 1 ( ) / 1 ( ), 2 ( ) 212009................................................ 2............................................ 115 (2009) 1... / 1 ( )........................................... 4 2... / 1 ( )......................................

More information

(2) (2) (3) (3) (5) ABI PRISM 7700 (5) Roche LightCycler TM (7) BioFlux LineGene (9) 1 RT-PCR (10) (12) (13) F. Hoffmann-La Roche Ltd. Roche Molecular

(2) (2) (3) (3) (5) ABI PRISM 7700 (5) Roche LightCycler TM (7) BioFlux LineGene (9) 1 RT-PCR (10) (12) (13) F. Hoffmann-La Roche Ltd. Roche Molecular 05-8 SYBR Green Realtime PCR Master Mix (Code No. QPK-201, QPK-201T) TOYOBO CO., LTD. Life Science Department OSAKA JAPAN A3314K (2) (2) (3) (3) (5) ABI PRISM 7700 (5) Roche LightCycler TM (7) BioFlux

More information

2

2 1999 No. 5 CHAPERONE NEWSLETTER CONTENTS 2 3 4 JEM JEM JEM, SEC, SCJ JEM JEM SCJ jem, scj 5 in vitro S. cerevisiae 6 K 7 in vitro Cell Mol. Cell in vitro 8 9 E. coli E. coli 10 in vitro ssc - b 11 in vivo

More information

9 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /,, No.0,,/+,/0 (,**/) 251 * * E#ects of Microbial Transglutaminase on Melting Point and Gel property of G

9 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /,, No.0,,/+,/0 (,**/) 251 * * E#ects of Microbial Transglutaminase on Melting Point and Gel property of G 9 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /,, No.0,,/+,/0 (,**/) 251 * * E#ects of Microbial Transglutaminase on Melting Point and Gel property of Gelatins Takahiko Soeda, Tomoko Kaneko*, Akiko Hokazono,

More information

< > Introduction to Basic Physical Chemistry 1,2 2 [ advanced [ [ [ [ [ KULASIS

< > Introduction to Basic Physical Chemistry 1,2 2 [ advanced [ [ [ [ [ KULASIS < > Introduction to Basic Organic Chemistry 1,2 [ 2 [ 10 11 12 13 14 15 [ [ [ [ KULASIS < > Introduction to Basic Physical Chemistry 1,2 2 [ advanced [ 11 12 14 15 [ [ [ [ KULASIS < > Introduction to Basic

More information

本文/YA3180D

本文/YA3180D pp. D- Frontier Science in Amino Acid and Protein Research D- D- N - D- D- D-DAP, EC D-DaaA Ser β- D D- Discovery of D-stereoselective amino acid amidases, and their use in kinetic resolution of amino

More information

(Quality of Life; QL) QL (Nerve Growth Factor; NGF) NGF PC12 6- (6-HITC) NGF NGF NGF PTP1B 6-HITC PTP1B NGF PTP1B 6-HITC PTP1B 6-HITC NGF 6-HITC 6-HITC in vivo 464-8601 Tel: 052-789-4126 20-Hydroxyecdysone

More information

d (i) (ii) 1 Georges[2] Maier [3] [1] ω = 0 1

d (i) (ii) 1 Georges[2] Maier [3] [1] ω = 0 1 16 5 19 10 d (i) (ii) 1 Georges[2] Maier [3] 2 10 1 [1] ω = 0 1 [4, 5] Dynamical Mean-Field Theory (DMFT) [2] DMFT I CPA [10] CPA CPA Σ(z) z CPA Σ(z) Σ(z) Σ(z) z - CPA Σ(z) DMFT Σ(z) CPA [6] 3 1960 [7]

More information

a L = Ψ éiγ c pa qaa mc ù êë ( - )- úû Ψ 1 Ψ 4 γ a a 0, 1,, 3 {γ a, γ b } η ab æi O ö æo ö β, σ = ço I α = è - ø çèσ O ø γ 0 x iβ γ i x iβα i

a L = Ψ éiγ c pa qaa mc ù êë ( - )- úû Ψ 1 Ψ 4 γ a a 0, 1,, 3 {γ a, γ b } η ab æi O ö æo ö β, σ = ço I α = è - ø çèσ O ø γ 0 x iβ γ i x iβα i 解説 4 matsuo.mamoru jaea.go.jp 4 eizi imr.tohoku.ac.jp 4 maekawa.sadamichi jaea.go.jp i ii iii i Gd Tb Dy g khz Pt ii iii Keywords vierbein 3 dreibein 4 vielbein torsion JST-ERATO 1 017 1. 1..1 a L = Ψ

More information

A b a B AaBb Ab ab 1 1 AB ab A-b a-b 2.Meiosis recombination Meiosis mitosis crossover recombination bivalent DNA 2

A b a B AaBb Ab ab 1 1 AB ab A-b a-b 2.Meiosis recombination Meiosis mitosis crossover recombination bivalent DNA 2 遺 伝 と 遺 伝 子 2007 年 度 参 考 問 題 リストの 解 答 例 xxax2002@yahoo.co.jp 2007 50 50 1. Mendel s second law of inheritance 2006 2006 A B A B Mendel s second law of inheritance principle of independent segregation P

More information

Note.tex 2008/09/19( )

Note.tex 2008/09/19( ) 1 20 9 19 2 1 5 1.1........................ 5 1.2............................. 8 2 9 2.1............................. 9 2.2.............................. 10 3 13 3.1.............................. 13 3.2..................................

More information

研究成果報告書

研究成果報告書 22 3 31 mrna mrna RNA β-casp family β-casp family RNA RNA Degradation of mrna plays an essential role in regulation of gene expression in all organisms. Defects in this process lead to potentially fatal

More information

本文/YAY116K

本文/YAY116K pp. GH GH GH β- - D- β- β- β- - EC J Alkalitolerant mechanism and improvement of alkalitolerancy of glycoside hydrolases Satoshi Nakamura Department of Bioengineering, Tokyo Institute of Technology, J

More information

untitled

untitled 2006 Chlamydomonas reinhardtii RNA 1070010 2007 3 20 p.3 p.3 p.4 p.7 p.8 p.8 p.9 p.9 2 [ ] RNA RNA RNA aada RNA RNAi-37 aph DNA Tag RNA Tag RESDA-PCR Tag Chlamydomonas reinhardtii Tag RNAi 176-10G Tag

More information

1) The Ribosome : Structure, Function and Evolu tion (ed. Hill, W. E., Dahlberg, A., Gerret, R. A. Moore, P. B., Schlessinger, D., Warner, J. R. American Society for Microbiology, Washington D.C. (1990)

More information

肺癌第50巻第4号

肺癌第50巻第4号 1 Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan; 2 Department of Thoracic Surgery, Aichi Cancer Center, Japan;

More information

Juntendo Medical Journal

Juntendo Medical Journal The hair growth effect of minoxidil Susumu OTOMO, Ph. D. Key words : minoxidil, minoxidil sulfate, hair growth, K+-channel opener, male pattern baldness Dept. of Pharmacology, Research Center Taisho Pharmaceutical

More information

Kazumitsu Ueda, E-mail : uedak@kais.kyoto-u.ac.jp http : //cseika-1, kais.kyoto-u.ac.j p Molecular mechanism of multidrug transporter MDR I : ABC in host-defense machinery 32P-ATP 1) Chen, C., Chin,

More information

RF_1

RF_1 RF_1 10/04/16 10:32 http://rftechno.web.infoseek.co.jp/rf_1.html 1/12 RF_1 10/04/16 10:32 http://rftechno.web.infoseek.co.jp/rf_1.html 2/12 RF_1 10/04/16 10:32 http://rftechno.web.infoseek.co.jp/rf_1.html

More information

T g T 0 T 0 fragile * ) 1 9) η T g T g /T *1. τ τ η = Gτ. G τ

T g T 0 T 0 fragile * ) 1 9) η T g T g /T *1. τ τ η = Gτ. G τ 615-851 ryoichi@chemekyoto-uacjp 66-852 onuki@scphyskyoto-uacjp 1 T g T T fragile *2 1 11) 1 9) η T g T g /T *1 τ 198 τ η = Gτ G τ T c η τ 12) strong fragile T c strong η η exp(e/k B T ) 1 2/3 E SiO 2

More information

研究成果報告書

研究成果報告書 20 6 UAA UGA UAG 20 Pyl. Pyl (AlocLys) N(epsilon)-benzyloxycarbonyl-lysine (ZLys) N(epsilon)-(o-azidobenzyloxycarbonyl) -lysine oazzlys (Yanagisawa et al., 2008b) N(epsilon)-(p-trifluoromethyldiazirinylbenzyloxy

More information

本文/YA9255F

本文/YA9255F pp. ATP ε ATP ATP ATP ε Bacillus PS ATP ATP H H µ H ATP ATP ADP µ H ATP FoF -ATP FoF -ATP µ H H ADP ATP H Na On the regulatory role of the epsilon subunit in ATP synthase Yasuyuki Kato-Yamada Department

More information

DiovNT

DiovNT Peptide Antisera and Monoclonal Antibodies (2) Antisera of Yanaihara Institute Inc. Monoclonal Antibodies Peptide Antisera and Antisera of Yanaihara Institute Inc. 274 Manufacturer: YANAIHARA INSTITUTE

More information

1 1 3 ABCD ABD AC BD E E BD 1 : 2 (1) AB = AD =, AB AD = (2) AE = AB + (3) A F AD AE 2 = AF = AB + AD AF AE = t AC = t AE AC FC = t = (4) ABD ABCD 1 1

1 1 3 ABCD ABD AC BD E E BD 1 : 2 (1) AB = AD =, AB AD = (2) AE = AB + (3) A F AD AE 2 = AF = AB + AD AF AE = t AC = t AE AC FC = t = (4) ABD ABCD 1 1 ABCD ABD AC BD E E BD : () AB = AD =, AB AD = () AE = AB + () A F AD AE = AF = AB + AD AF AE = t AC = t AE AC FC = t = (4) ABD ABCD AB + AD AB + 7 9 AD AB + AD AB + 9 7 4 9 AD () AB sin π = AB = ABD AD

More information

2

2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 10 6 15 7 13 7 14 13 31 13 13 9 30 13 10 14 13 10 25 13 11 29 13 11 30 14 111 14 223 14 2 23 3 17 14 3 17 14 3 21 14 3 26 13 11 29 5 2 2 14 1 11 1 3 28 1 3 14 2 28 1 28

More information

(nod/nol/noe) Nod 1B Nod 1B Nod Nod 2) Nod Nod Ca 2+ 3,4) 7,000 5) Myc Nem nod, exo nif, fix 2000 Mesorhizobium loti 2002 Bradyrhizobium japonicum DNA

(nod/nol/noe) Nod 1B Nod 1B Nod Nod 2) Nod Nod Ca 2+ 3,4) 7,000 5) Myc Nem nod, exo nif, fix 2000 Mesorhizobium loti 2002 Bradyrhizobium japonicum DNA 63 110 1) 1A 1980 1BC (nod/nol/noe) Nod 1B Nod 1B Nod Nod 2) Nod Nod Ca 2+ 3,4) 7,000 5) Myc Nem nod, exo nif, fix 2000 Mesorhizobium loti 2002 Bradyrhizobium japonicum DNA 6, 7) (Symbiosis island) t-rna

More information

37-4.indd

37-4.indd ISSN 0916-3328 東京大学アイソトープ総合センター VOL. 37 NO. 4 2007. 3. 26 アイソトープ総合センターの将来展望 40 18 18 20 3 800 1/3 1300 14 18 20 3 19 2 生きた細胞内の分子過程を 時間 空間計測する蛍光プローブの開発 1. はじめに Fura-2 Fura-2 198 1, 2 3, 4 2. 生体脂質分子の機能とその分析

More information

(2) (3) (3) (4) (5) ABI PRISM 7700 (5) Roche LightCycler TM (7) BioFlux LineGene (9) (10) (12) F. Hoffmann-La Roche Ltd. Roche Molecular Systems Inc.

(2) (3) (3) (4) (5) ABI PRISM 7700 (5) Roche LightCycler TM (7) BioFlux LineGene (9) (10) (12) F. Hoffmann-La Roche Ltd. Roche Molecular Systems Inc. 06-08 SYBR Green Realtime PCR Master Mix -Plus- (Code No. QPK-211, 211T) TOYOBO CO., LTD. Life Science Department OSAKA JAPAN (2) (3) (3) (4) (5) ABI PRISM 7700 (5) Roche LightCycler TM (7) BioFlux LineGene

More information

drug development Toshimi Michigami, E-mail : michigami@mch.pref.osaka.jp Keiichi Ozono, E-mail : keioz@ped.med.osaka-u.ac.jp The progress in the research on vitamin D 1) McCollum, E. V. et al.:

More information

研究成果報告書

研究成果報告書 21 5 28 2007 2008 CARElk CARPXR CAR CAR EST cdna CAR CAR 10FCS 96 SW480 HepG2 anti-lamin A/C anti-phospho-histone H3 anti-cyclin D1 G1 anti-cyclin A S CAR lamin A/C CAR Fig. 1 Lamin A/C /G1 lamin A/C G1

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 1) Bittner, J. J.: Science, 84, 162 (1936) 13) Michalides, R., van Ooyen, A., Nusse, R.: Curr. Top. Microbiol. Immunol., 106, 57-74 (1983) 2 z Yamamoto, K. R.: Ann. Rev. Genn., 19, 209-252 (1985) 3) Evans,

More information

x, y x 3 y xy 3 x 2 y + xy 2 x 3 + y 3 = x 3 y xy 3 x 2 y + xy 2 x 3 + y 3 = 15 xy (x y) (x + y) xy (x y) (x y) ( x 2 + xy + y 2) = 15 (x y)

x, y x 3 y xy 3 x 2 y + xy 2 x 3 + y 3 = x 3 y xy 3 x 2 y + xy 2 x 3 + y 3 = 15 xy (x y) (x + y) xy (x y) (x y) ( x 2 + xy + y 2) = 15 (x y) x, y x 3 y xy 3 x 2 y + xy 2 x 3 + y 3 = 15 1 1977 x 3 y xy 3 x 2 y + xy 2 x 3 + y 3 = 15 xy (x y) (x + y) xy (x y) (x y) ( x 2 + xy + y 2) = 15 (x y) ( x 2 y + xy 2 x 2 2xy y 2) = 15 (x y) (x + y) (xy

More information

function2.pdf

function2.pdf 2... 1 2009, http://c-faculty.chuo-u.ac.jp/ nishioka/ 2 11 38 : 5) i) [], : 84 85 86 87 88 89 1000 ) 13 22 33 56 92 147 140 120 100 80 60 40 20 1 2 3 4 5 7.1 7 7.1 1. *1 e = 2.7182 ) fx) e x, x R : 7.1)

More information

- 2 -

- 2 - - 1 - RI Martin D. Kamen P450 MD Kamen Vanderbilt Howard Gest Indiana 32 P J. Biol. Chem., 1948 15N - 2 - - 3 - ATP ATP-DnaA/oriC DnaB DnaC DnaG DNA III B (pol III* + β ) G B G pol III* β - 4 - β Hda A

More information

研究会プログラム.doc

研究会プログラム.doc 10 6 0:30-0:40 Session 0:40-1:10 Rac Michelle Lennartz 1:10-1:40 nnos 1:40-2:10 2:10-2:20 Session 2:20-2:50 2:50-3:20 NMDA NR1 3:20-3:50 GABA 3:50-4:00 Session 4:00-4:30 4:30-5:00 Vacuolar-type H + -ATPase

More information

Perl + α. : DNA, mrna,,

Perl + α. : DNA, mrna,, 2009 Perl + α. : DNA, mrna,, DNA .. DNA A C G T DNA 2 A-T, C-G DNA NH 2 NH 2 O - O O N P O - O CH 2 O N N O - O P O CH 2 O N O - O O P O NH 2 O - O - N CH 2 O N O OH OH OH DNA or RNA (U) (A) (G) (C)

More information

untitled

untitled -1- -2- -3- AED -4- 2-5- -6- -7- -8-6-1-28 048-833-1231 2-1-1 048-261-3119 4389-1 048-556-3005 1-13-11 04-2924-1311 2097-1 048-738-3111 1172 04-2953-7111 990-1 048-565-1919 537 048-775-1311 2-2-2 048-924-2111

More information

clover-375.pdf

clover-375.pdf 8:4511:00 9:0012:30 9:0016:3003-5986-3188 AM PM AM PM AM PM AM PM AM PM AM PM - - - - - - 1 2 3 5 6 7 8:4515:00 9:0016:30 AM PM AM PM AM PM AM PM AM PM AM PM - - - - - - - - - () - - - - - - - 8 10 12

More information

.i...j...[.X8-2

.i...j...[.X8-2 Vol. 8 No.2 Nov. 2007 1 2 4 12 20 37 45 54 56 62 1 2 3 4 5 7 6 8 9 10 11 13 12 15 14 17 16 19 18 21 20 Hatena 23 22 Oidiodendron Oidiodendron 25 24 Monosiga ovata Monosiga 27 26 Toxoplasma gondii 29 28

More information

untitled

untitled ICT ICT 1 ICT 2 ICT 3 ICT 4 ICT 5 ICT 6 ICT 7 ICT 8 ICT 9 ICT 10 ICT 11 ICT 12 ICT 13 ICT 14 ICT 15 ICT 16 ICT 17 ICT 18 ICT 19 ICT 20 ICT 21 ICT 22 ICT 23 ICT 24 ICT 25 ICT 26 ICT 27 ICT 28 ICT 29 ICT

More information

Correlation between molecular evolution of P450s and evolution of plant secondary metabolism Masaharu Mizutani E-mail : mizutani@scl.kyoto-u.ac.jp URL : http://biofun.kuicr.kyoto-u.ac.jp/index-j.html 13)

More information

Teru Ogura, Tomoko Yamada-Inagawa, E-mail : ogura@gpo.kumamotou.ac.jp AAA family ATPases : ring-shaped chaperones which catalyze energy-dependent conformational changes of proteins 29) Braun, S.,

More information

Vol.42 No.1/◇0 目次[三]3.2

Vol.42 No.1/◇0 目次[三]3.2 Department of Applied Biology and Chemistry, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1 1 1, Sakuragaoka, Setagaya-ku, Tokyo 156 8502 Hitachi Health Management Center, 4 3 16, Osecho,

More information

現代物理化学 2-1(9)16.ppt

現代物理化学 2-1(9)16.ppt --- S A, G U S S ds = d 'Q r / ΔS = S S = ds =,r,r d 'Q r r S -- ds = d 'Q r / ΔS = S S = ds =,r,r d 'Q r r d Q r e = P e = P ΔS d 'Q / e (d'q / e ) --3,e Q W Q (> 0),e e ΔU = Q + W = (Q + Q ) + W = 0

More information

448 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /,, No.+*,..2./- (,**/) 14 * * The E#ect of Peptides on the Physical Properties of Soy Protein Gel Takah

448 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /,, No.+*,..2./- (,**/) 14 * * The E#ect of Peptides on the Physical Properties of Soy Protein Gel Takah 448 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /,, No.+*,..2./- (,**/) 14 * * The E#ect of Peptides on the Physical Properties of Soy Protein Gel Takahiko Soeda, Akiko Hokazono and Katutoshi Yamazaki* Department

More information