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1 ABI PRISM 310 Genetic Analyzer A Benchmark in Laboratory Automation
2 ABI PRISM 310 Genetic Analyzer DNA ABI PRISM 310 DNA DNA ABI PRISM DNA ABI PRISM 310 DNA SSCP Long PCR RT-PCR ABI PRISM 310 ABI PRISM ABI PRISM 310
3 ABI PRISM X Y Z DNA DNA CCD
4 DNA ABI PRISM 310 ABI PRISM 310 POP-6 Performance Optimized Polymer POP ABI PRISM POP
5 ABI PRISM 310 ABI PRISM 12 ABI PRISM 310 CCD
6 ABI PRISM 310 GeneMapper Process Based Quality Values PQV PQV Pass Check Low Quality 3 GeneMapper Genotype PQV ADO = allele display overflow (check box) AEH = allele edit history (check box) SHP = sharp peak ANE = allele number error OBA = one base pair allele SPA = single peak artifact BIN = out of bin allele PHR = peak height ratio LPH = low peak height SPU = spectral pull-up BD = broad peak SP = split peak OS = offscale CC = control concordance OP = overlap NB = narrow bin DP = double peak GQ = genotype quality SNaPshot Multiplex GeneMapper SNaPshot Multiplex 36cm POP GeneScan -120 LIZ
7 SeqScape SeqScape SeqScape
8 ABI PRISM 1 ABI PRISM ABI PRISM ABI PRISM 310 ABI PRISM GeneMapper DNA Sequencing Analysis GeneMapper SNP API PRISM 310 DNA Sequencing Analysis SeqScape SNP Comparative Sequencing
9 ABI PRISM ABI PRISM DNA ABI PRISM 310 ABI PRISM DNA ABI PRISM 310 ABI PRISM GeneMapper SeqScape Windows ABI PRISM DNA DNA ABI PRISM PCR PCR ABI PRISM 310 Windows Macintosh ABI PRISM 310 ABI PRISM 310
10 525nm 650nm CCD ABI PRISM 488nm 514nm10mW , mm 558.8mm 863.6mm 94.5kg 127mm 100/120V, 50/60Hz, 15A, 1500W
11 ABI PRISM 10,000 ABI PRISM 310 ABI PRISM 310 ABI PRISM 310 ABI PRISM 310 ABI PRISM 310 Deuring R, Fanti L, Armstrong JA, et al. The ISW chromatinremodeling protein is required for gene-expression and the maintenance of higher order chromatin structure in vivo. Molecular Cell 2000;5: George KS, Zhao X, Gallahan D.Capillary electrophoresis methodol-ogy for identification of cancer related gene expression patterns of fluorescent differential display polymerase chain reaction. J Chromatogr B Biomed Sci Appl 1997;694(1): Herrmann BG, Koschorz B, Wertz K, McLaughlin KJ, Kispert A. A protein kinase encoded by the complex responder gene causes non-mendelian inheritance. Nature 1999;402: Inoue Y, Nishio H, Shirakawa T, et al. Detection of mutations in the COL4A5 gene in over 90% of male patients with X-linked Alport's syndrome by RT-PCR and direct sequencing. Am J Kidney Dis 1999; 34(5): Jackson RW, Athanassopoulos E, Tsiamis G, et al. Identification of a pathogenicity island, which contains genes for virulence and avirulence, on a large native plasmid in the bean pathogen Pseudomonas syringae path-ovar phaseolicola. PNAS USA 1999;96: Klungland A, Rosewell I, Hollenbach S, et al. Accumulation of premuta-genic DNA lesions in mice defective in removal of oxidative base damage. PNAS USA 1999;96(23): Kobayashi K, Sinasac DS, Iijima M, et al. The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein. Nat Genetics 1999;22: Lazaruk K, Walsh PS, Oaks F, et al. Genotyping of forensic short tandem repeat (STR) systems based on sizing precision in a capillary electrophoresis instrument. Electrophoresis 1998;19: Ogas J, Kaufmann S, Henderson J, Somerville C. PICKLE is a CHD3 chromatin-remodeling factor that regulates the transition from embryonic to vegetative development in Arabidopsis. PNAS 1999; 96(24): Sacchetti L, Calcagno G, Coto I, Tinto N, Vuttariello E, Salvatore F. Efficiency of two different nine-loci short tandem repeat systems for DNA typing purposes. Clin Chem 1999;45(2): Thomas MG, Parfitt T, Weiss DA, et al. Y chromosomes traveling south: the Cohen modal haplotype and the origins of the Lambathe "Black Jews of Africa." Am J Hum Genet 2000;66(2): Tomer Y, Barbesino G, Greenberg DA, Concepcion E, Davies TF.Linkage analysis of candidate genes in autoimmune thyroid disease, III:detailed analysis of chromosome 14 localizes Graves' disease-1 (GD-1) close to multinodular goiter-1 (MNG) ----International Consortium for the Genetics of Autoimmune Thyroid Disease. J Clin Endocrinol Metab 1998;83(12): Turenne, CY, Saanche, SE, Hoban DJ, Karlowsky JA, Kabani AM. Rapid identification of fungi by using the ITS2 genetic region and an automated fluorescent capillary electrophoresis system. J Clin Microbiol 1999;37(6):
12 The trademarks mentioned herein are the property of Life Technologies Corporation or their respective owners Life Technologies Japan Ltd,. All rights reserved. Printed in Japan. GA050-L1206OB TEL FAX TEL FAX
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