本文/YAY116L
|
|
- ときな たなせ
- 5 years ago
- Views:
Transcription
1 pp. Organic solvent-tolerant enzymes Hiroyasu Ogino Osaka Prefecture University, Gakuencho, Naka-ku, Sakai, Osaka, Japan
2 Pseudomonas aeruginosa PST- Pseudomonas aeruginosa LST- P. aeruginosa PST- Pseudomonas P. aeruginosa LST- P. aeruginosa PST- P. aeruginosa LST- LST- DMSO
3 C P. putida; Pseudomonas putida, P. fluorescencs; Pseudomonas fluorescencs, P. chlororaphis; Pseudomonas chlororaphis, P. flagi; Pseudomonas flagi, E. coli; Escherichia coli, M. luteus; Micrococcus luteus, B. subtilis; Bacillus subtilis. PST- α DMSO - tert- - DMF - -
4 P. aeruginosa LST- DNA Lip Lip LST- P. aeruginosa PST- PST- PST- C α- CD PST- CD CD α- CD CD CD CD α CD β CD PST- α β PST- PST- PST- C Cys- Cys- PST- N Cys- Cys- PST- Cys- Cys- PST- PST- PST- PST- α- CD C CD
5 CD C CD LST- DMSO LST- PST- DMSO PST- DMSO Cbz -Arg Leu-NH Cbz-Arg-Leu-NH PST- Cbz-Arg-Leu-NH DMSO PST- PST- PST- PST-
6 1 1 1 4 生化学 第8 1巻 第1 2号 図5 PST-0 1プロテアーゼとサーモライ シンの立体構造 全体構造をリボンモデル 活性中心とジ スルフィド結合を形成するアミノ酸を ボールアンドスティックモデル 酵素に 配位している亜鉛イオン 小 とカルシ ウムイオン 大 を充填モデルで示す 図6 有機溶媒耐性が変化した変異 PST-0 1プロテアーゼの変異箇所 全体構造をワイヤーモデル 変異したアミノ酸残基を充填モデルで示す
7 LST- LST- DMSO LST--R LST--R SK TF SR SL GR GV SR SW DN LST--R SL LST--R LH PST- PST- Cbz-Arg-Leu-NH mm Cbz-Arg mm Leu-NH ph C PST- mm Cbz-Asp mm Phe-OMe ph C
8 PST- subsite PST- mm Cbz-Asp mm Phe-OMe ph C Ogino, H.in Protein Adaptation in Extremophiles Siddiqui, K.S. & Thomas, T. eds., pp., Nova Science Publishers, Inc., New York. Ogino, H. & Ishikawa, H.J. Biosci. Bioeng.,,. Zaks, A. & Klibanov, A.M.Proc. Natl. Acad. Sci. USA,,. pp. pp. Ogino, H., Miyamoto, K., & Ishikawa, H.Appl. Environ. Microbiol.,,. Ogino, H., Yasui, K., Shiotani, T., Ishihara, T., & Ishikawa, H. Appl. Environ. Microbiol.,,. Ogino, H., Yasui, K., Watanabe, F., & Ishikawa, H. Ann. NY. Acad. Sci.,,. Ogino, H., Miyamoto, K., Yasuda, M., Ishimi, K., & Ishikawa, H.Biochem. Eng. J.,,. Ito, T., Kikuta, H., Nagamori, E., Honda, H., Ogino, H., Ishikawa, H., & Kobayashi, T.J. Biosci. Bioeng.,,. Ogino, H., Nakagawa, S., Shinya, K., Muto, T., Fujimura, N., Yasuda, M., & Ishikawa, H.J. Biosci. Bioeng.,,.
9 Pseudomonas aeruginosa LST- Cryptococcus sp. S- Rhizopus oryzae Burkholderia cepacia AKU- Streptomyces rimosus R -W Kurtzmanomyces sp. I- Bacillus sphaericus y Pseudomonas sp. S Bacillus megaterium CCOC-P Bacillus thermoleovorans CCR Penicillium chrysogenum Pseudomonas aeruginosa MTCC Bacillus sp. Pseudomonas aeruginosa san-ai Pyrobaculum calidifontis VA Bacillus licheniformis S- Bacillus sp. Sulfolobus solfataricus P Pseudomonas aeruginosa PST- Lumbricus rubellus Bacillus cereus BG Pseudomonas aeruginosa strain K Pseudomonas aeruginosa san-ai Bacillus licheniformis RSP-- Bacillus sp. APR- Pseudomonas aeruginosa PD Pseudomonas aeruginosa PseA a gamma-proteobacterium DGII Pseudomonas aeruginosa B- Bacillus cereus Aquifex aeolicus L Fasciola hepatica α- Haloarcula sp. S- Brachybacterium sp. strain LB Rhodococcus ruber DSM α- Streptomyces thermocyaneoviolaceus IFO Burkholderia cepacia ST- Chromobacterium sp. DS- Elaies guineensis Streptomyces sp. REN- Staphylococcus warneri ISK- Pyrococcus furiosus Paenibacillus illinoisensis ST- K Bacillus sp. BC Ogino, H., Katou, Y., Akagi, R., Mimitsuka, T., Hiroshima, S., Gemba, Y., Doukyu, N., Yasuda, M., Ishimi, K., & Ishikawa, H.Extremophiles,,. Ogino, H., Inoue, S., Akagi, R., Yasuda, M., Doukyu, N., & Ishimi, K.Biochem. Eng. J.,,. Ogino, H., Hiroshima, S., Hirose, S., Yasuda, M., Ishimi, K., & Ishikawa, H.Mol. Genet. Genomics,,. Ogino, H., Mimitsuka, T., Muto, T., Matsumura, M., Yasuda, M., Ishimi, K., & Ishikawa, H.J. Mol. Microbiol. Biotechnol.,,. Ogino, H., Watanabe, F., Yamada, M., Nakagawa, S., Hirose, T., Noguchi, A., Yasuda, M., & Ishikawa, H.J. Biosci. Bioeng.,,. Ogino, H., Gemba, Y., Yutori, Y., Doukyu, N., Ishimi, K., & Ishikawa, H.Biotechnol. Prog.,,. Ogino, H., Yokoo, J., Watanabe, F., & Ishikawa, H. Biochem. Eng. J.,,. Ogino, H., Uchiho, T., Yokoo, J., Kobayashi, R., Ichise, R., & Ishikawa, H.Appl. Environ. Microbiol.,,. Ogino, H., Uchiho, T., Doukyu, N., Yasuda, M., Ishimi, K., & Ishikawa, H.Biochem. Biophys. Res. Commun.,,. Kawata, T. & Ogino, H.Biotechnol. Prog., in press. Ogino, H., Gemba, Y., Yamada, M., Shizuka, M., Yasuda, M., & Ishikawa, H.Biochem. Eng. J.,,. Ogino, H., Yamada, M., Watanabe, F., Ichinose, H., Yasuda,
10 M., & Ishikawa, H.J. Biosci. Bioeng.,,. Bobe, I.M., Abdelmoez, W., Ogino, H., Yasuda, M., Ishimi, K., & Ishikawa, H.Biotechnol. Bioeng.,,. Tsuchiyama, S., Doukyu, N., Yasuda, M., Ishimi, K., & Ogino, H.Biotechnol. Prog.,,. Kamini, N.R., Fujii, T., Kurosu, T., & Iefuji, H.Process Biochem.,,. Hiol, A., Jonzo, M.D., Rugani, N., Druet, D., Sarda, L., & Comeau, L.C.Enzyme Microb. Technol.,,. Ishimoto,R.,Sugimoto,M.,&Kawai,F.FEMS Microbiol. Lett.,,. Lescic, I., Vukelic, B.,Majeric -Elenkov, M., Saenger, W., & Abramic, M.Enzyme Microb. Technol.,,. Kakugawa, K., Shobayashi, M., Suzuki, O., & Miyakawa, T. Biosci. Biotechnol. Biochem.,,. Hun, C.J., Rahman, R.N.Z.A., Salleh, A.B., & Basri, M. Biochem. Eng. J.,,. Rahman, R.N.Z.A., Chin, J.H., Salleh, A.B., & Basri, M. Mol. Gen. Genomics,,. Baharum, S.N., Salleh, A.B., Razak, C.N.A., Basri, M., Rahman, M.B.A., & Rahman, R.N.Z.R.A.Ann. Microbiol.,,. Rahman, R.N.Z.R.A., Baharum, S.N., Basri, M., & Salleh, A.B. Anal. Biochem.,,. Lima, V.M.G., Krieger, N., Mitchell, D.A., Baratti, J.C., de Filippis, I., & Fontana, J.D.J. Mol. Catal B: Enzym.,,. Castro-Ochoa, L.D., Rodrl guez-gómez, C., Valerio-Alfaro, G., &Ros,R.O.Enzyme Microb. Technol.,,. Bancerz, R., Ginalska, G., Fiedurek, J., & Gromada, A. J. Ind. Microbiol. Biotechnol.,,. Singh, S. & Banerjee, U.C.J. Mol. Catal. B: Enzym.,,. Eltaweel, M.A., Rahman, R.N.Z.R.A., Salleh, A.B., & Basri, M.Ann. Microbiol.,,. Karadzic, I., Masui, A., Zivkovic, L.I., & Fujiwara, N. J. Biosci. Bioeng.,,. Hotta, Y., Ezaki, S., Atomi, H., & Imanaka, T.Appl. Environ. Microbiol.,,. Torres, S. & Castro, G.R.New horizons in biotechnology, pp., Kluwer Academic Publishers, Dordrecht. Torresa, S., Baigorl, M.D., & Castro, G.R.Process Biochem.,,. Karpushova, A., Brümmer, F., Barth, S., Lange, S., & Schmid, R.D.. Appl. Microbiol. Biotechnol.,,. Park, Y.-J., Choi, S.Y., & Lee, H.-B.Biochim. Biophys. Acta,,. Nakajima, N, Sugimoto, M, & Ishihara, K.J. Biosci. Bioeng.,,. Ghorbel, B., Sellami-Kamoun, A., & Nasri, M.Enzyme Microb. Technol.,,. Geok, L.P., Razak, C.N.A., Rahman, R.N.Z.A., Basri, M., & Salleh, A.B.Biochem. Eng. J.,,. Rahman, R.N.Z.R.A., Geok, L.P., Basri, M., & Salleh, A.B. Enzyme Microb. Technol.,,. Karadzic, I., Masui, A., & Fujiwara, N.J. Biosci. Bioeng.,,. Sareen, R., Bornscheuer, U.T., & Mishra, P.J. Mol. Catal. B: Enzym.,,. Sareen, R., Bornscheuer, U.T., & Mishra, P.Biotechnol. Lett.,,. Kumar, D. & Bhalla, T.C.Indian J. Exp. Biol.,,. Najafi, M.F., Deobagkar, D., & Deobagkar, D.Electr. J. Biotechnol.,,. Gupta, A., Roy, I., Khare, S.K., & Gupta, M.N.J. Chromatogr. A,,. Gupta, A. & Khare, S.K.Bioresource Technol.,,. Sana, B., Ghosh, D., Saha, M., & Mukherjee, J.Process Biochem.,,. Khan, S., Misra, A.K., Tripathi, C.K.M., Mishra, B.N., & Bihari, V.Indian J. Exp. Biol.,,. Shafee, N., Tan, C.-C., Mahamad, S., Rahman, R.N.Z.A., Basri, M., & Salleh, A.B.Ann. Microbiol.,,. Khan, A.R., Nirasawa, S., Kaneko, S., Shimonishi, T., & Hayashi, K.Enzyme Microb. Technol.,,. Dowd, A.J., Dooley, M., Fagain, C., & Dalton, J.P.Enzyme Microb. Technol.,,. Fukushima, T., Mizuki, T., Echigo, A., Inoue, A., & Usami, R. Extremophiles,,. Doukyu, N., Yamagishi, W., Kuwahara, H., Ogino, H., & Furuki, N.Extremophiles,,. Doukyu, N., Yamagishi, W., Kuwahara, H., & Ogino, H. Biosci. Biotechnol. Biochem.,,. Kosjek, B., Stampfer, W., Pogorevc, M., Goessler, W., Faber, K., & Kroutil, W.Biotechnol. Bioeng.,,. Ishihara, K., Yamaguchi, H., Hamada, H., Nakamura, K., & Nakajima, N.J. Mol. Catal. B-Enzym.,,. Doukyu, N. & Aono, R.Appl. Microbiol. Biotechnol.,,. Takeda, Y., Aono, R., & Doukyu, N.Extremophiles,,. Doukyu, N., Shibata, K., & Ogino, H.Appl. Microbiol. Biotechnol.,,. Doukyu, N., Shibata, K., Ogino, H., & Sagermann, M. Appl. Microbiol. Biotechnol.,,. Sakharov, I.Yu., Castillo, J., Areza, J.C., & Galaev, I.Yu. Bioseparation,,. Rodakiewicz-Nowak, J. & Ito, M.J. Chem. Technol. Biotechnol.,,. Mizuno, K., Fukuda, D., Kakihara, M., Kohno, M., Ha, T.L., Sonomoto, K., & Ishizaki, A.Food Sci. Technol. Res.,,. Cacciapuoti, G., Bertoldo, C., Brio, A., Zappia, V., & Porcelli, M.Extremophiles,,. Doukyu, N., Kuwahara, H., & Aono, R. Biosci. Biotechnol. Biochem.,,. Sardessai, Y. & Bhosle, S.Mar. Biotechnol.,,.
10中西_他.indd
Streptomyces mobaraensis N N N Sm b Sm N N Sm Sm Sm ' ' Sm Sm ak K k K bk k K Sm Sm a b S. mobaraensis a b a b Sm b b bb b b Sm Sm S. lividans ab Sm ab Sm ab ab ab ab SmSm S. lividansab S. lividans ab
More informationThe function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Database Center for Life Science Online Service Key words Shigey
The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Key words Shigeyuki Kawai, Chikako Fukuda, Kousaku Murata E-mail : kawais@kais.kyoto-u.ac.jp, chikakko@kais.kyotou.ac.jp,
More informationTECN
WKO BIO WINDOW lyo in situ wako No.13 UG. 1998 TECN TECN l l l l l l l hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh lyo lyo l J.Clin. Biochem. Nutr., Mebio hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh
More information本文/YA3180D
pp. D- Frontier Science in Amino Acid and Protein Research D- D- N - D- D- D-DAP, EC D-DaaA Ser β- D D- Discovery of D-stereoselective amino acid amidases, and their use in kinetic resolution of amino
More informationVol.40 No.5△/△0 目次[三]10.23
! Department of Management, Miyagi University, 2 2 1 Hatatate Taihaku-ku Sendai, Miyagi 982 0215 Industrial Technology Institute, Miyagi Prefectural Government, 2 2 Akedoori Izumi-ku Sendai, Miyagi 981
More information本文/YAY116K
pp. GH GH GH β- - D- β- β- β- - EC J Alkalitolerant mechanism and improvement of alkalitolerancy of glycoside hydrolases Satoshi Nakamura Department of Bioengineering, Tokyo Institute of Technology, J
More informationDatabase Center for Life Science Online Service (http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*,
(http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*, E mail : takaabe@mail.cc.tohoku.ac.jp Taro Tokui, Molecular identification of organic anion transporter
More information2007 Vol.56 No.6 総説 丸山浩樹
Reprinted from RADIOISOTOPES, Vol.56,.6 June 2007 Japan Radioisotope Association http : //www.jrias.or.jp/ α β α β ε m z α µ µ α m z m z µ µ Curr. Opin. Biotechnol J. Proteome Res Rapid Commun. Mass
More informationGH_013_JP.indb
GH CONTENTS 2 3 4 5 6 7 8 9 1 14 15 18 19 2 21 22 24 25 26 27 33 34 34 35 36 37 38 39 1 GH 7 GH 17 GH 24 2 GH 4 3 4 5 1. 2. 3. 4. 5. 6. 7. 8. 6 7 8 GH7 GH17 GH24 GH4 GH1 11 461/41 4.25 1-5 21 21 69 5
More informationその科学と技術 No.48( )
45 CI +,,* a-, +0 a-, +0 a-, +., a-, + +, - +, CD CF - CTS CD a-cd b-cd g-cd a- +., 0 1 2 - +33-. CI CI CD CD a- +., CI a- +0, CD Bacillus circulans T--*.*. 13 a-, +0 CI-1 CI-2. CI-3 +* / CI 0 CI-1 CI-+1
More informationCorrelation between molecular evolution of P450s and evolution of plant secondary metabolism Masaharu Mizutani E-mail : mizutani@scl.kyoto-u.ac.jp URL : http://biofun.kuicr.kyoto-u.ac.jp/index-j.html 13)
More information- 1 -
- 1 - - 1 - ... 1... 2... 4... 5... 9... 11... 14... 16... 20... 21... 22... 23... 23 - 1 - - 2 - - 3 - - 4 - - 5 - - 6 - - 7 - - 8 - - 9 - ( ) - 10 - - 11 - Pseudomonas aeruginosa Escherichia coli Staphylococcus
More information2001 Mg-Zn-Y LPSO(Long Period Stacking Order) Mg,,,. LPSO ( ), Mg, Zn,Y. Mg Zn, Y fcc( ) L1 2. LPSO Mg,., Mg L1 2, Zn,Y,, Y.,, Zn, Y Mg. Zn,Y., 926, 1
Mg-LPSO 2566 2016 3 2001 Mg-Zn-Y LPSO(Long Period Stacking Order) Mg,,,. LPSO ( ), Mg, Zn,Y. Mg Zn, Y fcc( ) L1 2. LPSO Mg,., Mg L1 2, Zn,Y,, Y.,, Zn, Y Mg. Zn,Y., 926, 1 1,.,,., 1 C 8, 2 A 9.., Zn,Y,.
More informationα Asparagus officinalis BoCam 1
α Asparagus officinalis BoCam 1 α α Asparagus officinalis BoCam1 α α α Department of Applied Biology and Chemistry, Faculty of Applied Bioscience, Tokyo University of Agriculture, Sakuragaoka 1 1 1, Setagaya
More information3) Z. Nambu: in preparation (1971). 4) N. P. Wilkins & J. D. Iles: Comp. Biochem. Physiol., 17, 1141 (1966). 5) V. M. Ingram: Nature, 235, 338 (1972). Bacillus cereus var. mycoides, Bacillus thuringiensis
More information本文/YA4278I
pp. D- D-DAO DAO D- D- D- D- o- DAO-D- D-DAO DAO Hans Krebs FAD X DAO DAO DAO D- Structure and reaction mechanism of D-amino acid oxidase Yasuzo Nishina School of Health Sciences, Kumamoto University,
More information本文/YA9255C
pp. E- -SH X in vitro in vivo -SH Structure-based drug development and medical biological application of cathepsin specific inhibitors Nobuhiko Katunuma Institute for Health Sciences, Tokushima Bunri University,Nishihamabouji,
More information2007050781......_.L.O...z.W
a s d f g a s d f g h j k l 0 in vitro in vivo in vitro in vivo in vivo in vivo in vitro Metabolism Metabolism Endocr Endocr Endocrinol Ann NYA cad Sci J clin Endocr Metab
More information内科96巻3号★/NAI3‐1(第22回試験問題)
µ µ α µ µ µ µ µ µ β β α γ µ Enterococcus faecalis Escherichia coli Legionella pneumophila Pseudomonas aeruginosa Streptococcus viridans α β 正解表正解記号問題 No. 正解記号問題 No. e(4.5) 26 e 1 a(1.2) 27 a 2
More information1...z04/08/.e2
August 2004 29 α α 30 Functional Glycomics News Letter No.4 α α August, 2004 31 β ü β α β α 32 Functional Glycomics News Letter No.4 α β August, 2004 33 34 Functional Glycomics News Letter No.4 α β ü August,
More informationDatabase Center for Life Science Online Service Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sap
Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060, Japan] Molecular Basis of Triplet Repeat Diseases : Genetic Instabillity and Unusual DNA
More informationBio-No.57/3....
2004. MAR. 3No.57 http://www.wako-chem.co.jp C O N T E N T S 2 Wako Bio Window No.57 MAR.2004 l l l l wako wako l l mmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmm Wako Bio Window No.57 MAR.2004 3 4 Wako Bio Window
More informationCHEMOTHERAPY 52 MAY d a a. Normal S. aureus d Đg/ml, 2h; e b b Đg/ml, Abnormal e. division lh; Abnormal thickening division cross f c. 1
Levloxacin V.:1 Z iiiir fa L CHEMOTHERAPY 52 MAY d a a. Normal S. aureus d. 0.39 Đg/ml, 2h; e b b. 0.10 Đg/ml, Abnormal e. division lh; Abnormal thickening division cross f c. 1992 0.39 Đg/ml, and Fig.
More information第十四改正日本薬局方第二追補
461 3 3 3 5 5 6 6 10 18 19 79 81 101 113 127 133 139 145 147 152 153 156 158 165 3 19 20 21 22 22 23 24 25 26 26 27 28 29 29 30 31 dl 32 dl 33 34 34 36 36 37 38 38 38 39 40 42 42 42 43 44 45 46 46 47 48
More informationDatabase Center for Life Science Online Service
1) Epps, H. M., Gale, E. F.: Biochem. J., 36, 619-623 (1942) 2) Monod, J.: Recherches sur la croissance des cultures bacteriennes, Ph. D. thesis. Her mann,paris (1942) 3) Magasanik, B.: Cold Spring Harbor
More information[Nippon Nogeikagaku Kaishi
[ Nippon Nageikagaku Kaishi Vol. 72, No. 11, pp. 1333 `1344, 1998 l Key words: methylotrophic yeast; gene expres sion; C1-metabolism; peroxisome Cellular Functions of the Methylotrophic Yeast: Their Molecular
More information本文/YA6280C
H., Hoshino, K., Kaisho, T., Kuwata, H., Takeushi, O., Takeshige,K.,Saitoh,T.,Yamaoka,S.,Yamamoto,N.,Yamamoto, S., Muta, T., Takeda, K., & Akira, S.Nature,,. Yamazaki, S., Muta, T., Matsuo, S., & Takeshige,
More information.i...j...[.X8-2
Vol. 8 No.2 Nov. 2007 1 2 4 12 20 37 45 54 56 62 1 2 3 4 5 7 6 8 9 10 11 13 12 15 14 17 16 19 18 21 20 Hatena 23 22 Oidiodendron Oidiodendron 25 24 Monosiga ovata Monosiga 27 26 Toxoplasma gondii 29 28
More informationFlorigen in rice Key words Shojiro Tamaki, Ko Shimamoto E-mail : s-tamaki@bs.naist.jp, simamoto@bs.naist.jp URL : http://bsw3.naist.jp/simamoto/simaoto.html 1) Thomas, B., Vince-prue, D.: Photoperiodism
More informationVarious function and toxicity of iron Key words 1) Hentze, M. W. et al: Cell, 117, 285-297 (2004) 2) Ganz, T.: Blood, 102, 783-788 (2003) 3) Nemeth, E. et al.: Science, 306, 2090-2093 (2004) 4) Hentze,
More informationdrug development Toshimi Michigami, E-mail : michigami@mch.pref.osaka.jp Keiichi Ozono, E-mail : keioz@ped.med.osaka-u.ac.jp The progress in the research on vitamin D 1) McCollum, E. V. et al.:
More informationKazumitsu Ueda, E-mail : uedak@kais.kyoto-u.ac.jp http : //cseika-1, kais.kyoto-u.ac.j p Molecular mechanism of multidrug transporter MDR I : ABC in host-defense machinery 32P-ATP 1) Chen, C., Chin,
More information第十四改正日本薬局方第一追補
395 3 5 7 7 7 7 8 16 17 19 159 161 181 207 231 231 233 235 240 253 259 263 3 19 19 21 21 22 22 23 24 25 26 26 26 26 26 26 27 27 28 44 45 45 46 48 49 49 49 50 51 52 53 54 54 55 55 56 56 57 57 58 59 60 61
More information1) P. Nurse, P. Thuriaux & K. Nasmyth: Mol. Gen. Genet., 145, 167 (1976). 2) R. Ohi, C. McCollum, B. Hirani, G.J. Den Hasse, X. Zhang, J.D. Burke, K. Turner & K.L. Gould: EMBO J., 13, 471 (1994). 3) T.
More information寄稿論文 高い発ガン活性を示す鉄キレートお構造特性 | 東京化成工業
NTBI = nontransferrin-bound iron NTBI DNA H DNA 2 NTBI NTBI NTBI NTBI NTBI NTBI (nta) (nta) (nta) NTBI (nta) (nta) NTBI (nta)ntbi Fe-(nta) (nta) N(CH 2 CH) 3 HCCH 2 NHCH 2 CH 2 NHCH 2 CH (HCCH 2 ) 2 NH
More informationKazumitsu Ueda, [Department of Applied Life Science, Kyoto University Graduate School of Agriculture, Kitashirakawa, Sakyo-ku, Kyoto 606-01, Japan] Molecular Mechanisms for Drug Transport by MDR1/P-glycoprotein
More information1) Murphy, T.H., Miyamoto, M., Sastre, A., Schnaar, R.L., Coyle, J.T.: Neuron, 2, 1547-1558 (1989) 2) Pellegrini-Giampietro, D.E., Cherici, G., Ale siani,m., Carla, V., Moroni, F.: J. Neuro science,10,
More information宿 主 特 異 性 を決 定 す る た め に非 常 に大 き な 役 割 を も った 割 を 演 じ る こ と に な る.ま 物 質 で あ る こ とは 間 違 い な い.ま た,Nod る菌 体 外 多 糖 の生 成 が菌 の 感 染 に 関与 して い る こ と も知 factorは マ メ科 植 物 根 細 胞 の 根 粒 形成 に 関 す る 遺 伝 子(nodulin gene)を
More information4) H. Takayama et al.: J. Med. Chem., 45, 1949 (2002). 5) H. Takayama et al.: J. Am. Chem. Soc., 112, 8635 (2000). 6) H. Takayama et al.: Tetrahedron Lett., 42, 2995 (2001). 9) M. Kitajima et al: Chem.
More informationさくらの個別指導 ( さくら教育研究所 ) A a 1 a 2 a 3 a n {a n } a 1 a n n n 1 n n 0 a n = 1 n 1 n n O n {a n } n a n α {a n } α {a
... A a a a 3 a n {a n } a a n n 3 n n n 0 a n = n n n O 3 4 5 6 n {a n } n a n α {a n } α {a n } α α {a n } a n n a n α a n = α n n 0 n = 0 3 4. ()..0.00 + (0.) n () 0. 0.0 0.00 ( 0.) n 0 0 c c c c c
More information本文/YA9255F
pp. ATP ε ATP ATP ATP ε Bacillus PS ATP ATP H H µ H ATP ATP ADP µ H ATP FoF -ATP FoF -ATP µ H H ADP ATP H Na On the regulatory role of the epsilon subunit in ATP synthase Yasuyuki Kato-Yamada Department
More information1) Y. Hatefi: Annu. Rev. Biochem., 54, 1015 (1985). 2) H. Weiss, T. Friedrich, G. Hofhaus & D. Preis: Eur. 4) M. Yamaguchi & Y. Hatefi: Biochemistry, 32, 1935 (1993). 5) K. Leonard, H. Haiker & H. Weiss:
More informationuntitled
(a) (b) (c) (d) (e) (f) (g) (f) (a), (b) 1 He Gleiter 1) 5-25 nm 1/2 Hall-Petch 10 nm Hall-Petch 2) 3) 4) 2 mm 5000% 5) 1(e) 20 µm Pd, Zr 1(f) Fe 6) 10 nm 2 8) Al-- 1,500 MPa 9) 2 Fe 73.5 Si 13.5 B 9 Nb
More informationNovel chemical mediators in the resolution of inflammation Charles N. Serhan Key words E-mail : marita@nih.go.jp Charles N. Serhan Brigham & Women's Hospital/Harvard Medical School 1) Serhan, C. N.,
More information[Department of Pediatrics, Gifu University School Clinical. Pathological and Biochemical Abnormality in peroxisomal Disorders 1) Goldfischer, S., Moore, C. L., Johnson, A. B., Spiro, A. J., Valsamis,
More information1) van Meer, G., Op den Kamp, J. A.: J. Cell. Biochem., 19, 193-2040982) 2) Gaffet, P., Bettache, N., Bienvenue, A.: Biochemistry, 34, 6762-6769(1995) 3) Sims, P. J., Wiedmer, T.: Thromb. Haemost., 86,
More information2
1999 No. 5 CHAPERONE NEWSLETTER CONTENTS 2 3 4 JEM JEM JEM, SEC, SCJ JEM JEM SCJ jem, scj 5 in vitro S. cerevisiae 6 K 7 in vitro Cell Mol. Cell in vitro 8 9 E. coli E. coli 10 in vitro ssc - b 11 in vivo
More informationMicrosoft Word - 支部会報とうきょう 平成21年度3号.doc
2009 12 24 1 (( ) 37 ) 22 3 6 9 00 6 15 8:30~ 9:00~12:14 13:00~16:27 16:40~17:40 17:45~18:15 18:30~ 1 1 2 1 3 19 20 1 (( ) 37 ) 20 21 22 * (http://idaten.c.u-tokyo.ac.jp/tokyo/). 2 9:00~10:30 14 24 7 TR
More informationCandida albicans In Vitro Diagnostics (13)--D-Glucan Determination Reagents
D 012 Candida albicans In Vitro Diagnostics (13)--D-Glucan Determination Reagents DATA : 1 DATA : 2 3 DATA : UNGITEC 1 1 DATA : 20pg/mL 1020pg/mL 10pg/mL (cut off 20pg/mL) 90.2%(37/41) 100%(85/85) 96.8%(122/126)
More information01NGRCnewsNo4.indd
NGRC No. 4 ... 4... 5... 67... 8... 9... 10 DNA... 11... 12... 13... 14 Mixia osmundae... 15... 16 24... 17... 1828... 2932 1 DDBJ 2012 5 2 1 SNP 2 Zhao et al., 2010 3 A B 4 1 1 1 2 1 DNA 1 2EMS Mutator
More informationT g T 0 T 0 fragile * ) 1 9) η T g T g /T *1. τ τ η = Gτ. G τ
615-851 ryoichi@chemekyoto-uacjp 66-852 onuki@scphyskyoto-uacjp 1 T g T T fragile *2 1 11) 1 9) η T g T g /T *1 τ 198 τ η = Gτ G τ T c η τ 12) strong fragile T c strong η η exp(e/k B T ) 1 2/3 E SiO 2
More information5 n P j j (P i,, P k, j 1) 1 n n ) φ(n) = n (1 1Pj [ ] φ φ P j j P j j = = = = = n = φ(p j j ) (P j j P j 1 j ) P j j ( 1 1 P j ) P j j ) (1 1Pj (1 1P
p P 1 n n n 1 φ(n) φ φ(1) = 1 1 n φ(n), n φ(n) = φ()φ(n) [ ] n 1 n 1 1 n 1 φ(n) φ() φ(n) 1 3 4 5 6 7 8 9 1 3 4 5 6 7 8 9 1 4 5 7 8 1 4 5 7 8 10 11 1 13 14 15 16 17 18 19 0 1 3 4 5 6 7 19 0 1 3 4 5 6 7
More informationAcecide_ProductsInformation2010PDF.indd
53-0115-00-4PDF 53-0115-00-4PDF INDEX 1 3 9 11 12 16 21 38 39 40 42 43 44 45 46 47 53-0115-00-4PDF 3 1 Critical Semicritical Noncritical Disinfection Sterilization 53-0115-00-4PDF 2 53-0115-00-4PDF O =
More informationDatabase Center for Life Science Online Service Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal
Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal transduction Needleman, R., Lanyi, J. K. : Science, 269,73-75 (1995) 3) Bogomolni, R. A., Stoeckenius,
More information45 セ ル ラ ー ゼ複 合 体 セ ル ロソ ー ム の構 造 と機 能 III.C.thermocellumの 1.セ セ ル ロ ソー ム ル ロソーム の概 念 セ ル ロソー ム は,は じめC.thermocellumの 細 胞 をセ ル ロ ー ス へ 結 合 させ る た め の セ ル ロ ー ス 結 合 因 子 と し て 見 い だ さ れ た が,こ れ が 多 数 の セ
More informationFragaria x ananassa Bioengineering College of Jimei University, Jimei, Xiamen 361021, Fujian Province, China Department of Food Science and Technology, Tokyo University of Marine Science and Technology,
More information秋田応用微生物研究会
13:00-13:30 13:30-13:50 Pseudomonas aeruginosa 13:50-14:10 14:10-14:30 Bacillus polymyxa KT551 * * 14:30-14:50 14:50-15:10 15:10-15:30 15:30-15:50 Streptomyces kasugaensis RNA rpoz * ** ** * ** 15:50-16:10
More informationC-1 210C f f f f f f f f f f f f f f f f f f f f r f f f f f f f f f f f f f R R
4 5 ff f f f f f f f f f f f f ff ff ff r f ff ff ff ff ff ff R R 7 b b ï φφ φφ φφ φ φ φφ φφφφφφφφ φφφφ φφφφ ù û û Æ φ ñ ó ò ô ö õ φφ! b ü ú ù û ü ß μ f f f f f f f f f f b b b z x c n 9 f φ φ φ φ φ φ
More information) a + b = i + 6 b c = 6i j ) a = 0 b = c = 0 ) â = i + j 0 ˆb = 4) a b = b c = j + ) cos α = cos β = 6) a ˆb = b ĉ = 0 7) a b = 6i j b c = i + 6j + 8)
4 4 ) a + b = i + 6 b c = 6i j ) a = 0 b = c = 0 ) â = i + j 0 ˆb = 4) a b = b c = j + ) cos α = cos β = 6) a ˆb = b ĉ = 0 7) a b = 6i j b c = i + 6j + 8) a b a b = 6i j 4 b c b c 9) a b = 4 a b) c = 7
More informationライフサイエンス関連 コラーゲン・ゼラチン製品案内 2015.12
3 mg/ml ph 3 4 8 1 Type I-A Type I-P Type I-A Type I-C Type III Type III Type IV Type IV TEL 072-820-3079 FAX 072-820-3095 4 8 4 Type I-A 20mL 1 F-12 MEM 5mL 1 4mL 5 10F-12MEM DFDME F-12 1 1199 5 DMERPMI-1640
More informationMinamiooya, Machida, Tokyo 194, Japan] RNA World, A Key Step in the Origin of Life : Inspection from the View Point of Biological Evolution 1) Crick, F. H. C.: Sym. Soc. Exp. Biol., 12, 548-555
More informationLactobacillus brevis γ
Lactobacillus brevis γ γ Lactobacillus brevis Pentaphylloides fruticosa National Institute of Fruit Tree Science, NARO, 2 1 Fujimoto, Tsukuba Ibaraki 305 8605 Key wordsethylene, fruit quality, shelf life,
More informationCRA3689A
AVIC-DRZ90 AVIC-DRZ80 2 3 4 5 66 7 88 9 10 10 10 11 12 13 14 15 1 1 0 OPEN ANGLE REMOTE WIDE SET UP AVIC-DRZ90 SOURCE OFF AV CONTROL MIC 2 16 17 1 2 0 0 1 AVIC-DRZ90 2 3 4 OPEN ANGLE REMOTE SOURCE OFF
More informationTomohiro Terada, Ken-ichi Inui, Peptide transporter family situ 1) Matthews, D.M. : Physiol. Rev., 55, 537-608(1975) 2) Ganapathy, V.. Leibach, F.H.: Am. J. Physiol. Gastro intest. Liver Physiol.,
More informationエコリシン点眼液/眼軟膏インタビューフォーム
2011 11 4 871319 1mL 5mg 5mg15 1g 5mg 5mg15 JAN JAN Erythromycin LactobionateJAN Colistin Sodium MethanesulfonateJAN 1970 3 31 1970 8 1 1970 7 20 TEL0120-921-839 06-6321-7056 9 17 https://www.santen.co.jp/medical/admin/a300.jsp
More information5200) [Department of Biochemistry, Miyazaki Medical College, Kihara, Kiyotake-cho, Miyazaki 889-16, Japan] Natriuretic Peptide Family: ANP and BNP 1) de Bold, A. J.: Science, 230, 767-770 (1985)
More information本組よこ/根間:文11-029_P377‐408
377 378 a b c d 379 p M NH p 380 p 381 a pp b T 382 c S pp p 383 p M M 384 a M b M 385 c M d M e M 386 a M b M a M 387 b M 388 p 389 a b c 390 391 a S H p p b S p 392 a T 393 b S p c S 394 A a b c d 395
More information…h…L…–…†…fi…g1
21 1326 1328 2002 22 4375 4377 2003 34 6 848 849 2005 9 10 15 1067 1070 1996 49 133 166 2003 1 2 2 3 4 4 1 3 23 311 313 2004 5 1 118 7604 7607 1996 15 1 33 6627 6629 2000 12 649 155 167 2003 76 23 7007
More information2017 NEW MODEL NISSIN V3 NISSIN ZEROSUM X NEW MODEL NEW MODEL NEW MODEL 2017 NEW MODEL NISSIN NISSIN V3 BG M
V ZEROSUM X4 20 7 20 7 V BG M 68 7894 6. 827 000749 BG L 67 8298 7. 828 00076 BG LL 7080 862 9. 829 00076 BG L 78 906 6. 80 000770 BR M 68 7894 6. 8 000787 BR L 67 8298 7. 82 000794 BR LL 7080 862 9. 8
More informationDatabase Center for Life Science Online Service archlaboratories, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki-shi, Kanagawa 213, Japan] Developmental Genetics of Caenorhabditis elegans Database Center for
More informationc 2009 i
I 2009 c 2009 i 0 1 0.0................................... 1 0.1.............................. 3 0.2.............................. 5 1 7 1.1................................. 7 1.2..............................
More informationタンパク質を物性科学的に見た場合、単なるアミド結合の集合体であると片づけるにはもったいなさすぎる
Precise Functional Analysis of Biological Macromolecules Promoted by the Encounter of Crystallographic and Spectroscopic Molecular Structure Analyses Takamitsu Kohzuma*, Sachiko Yanagisawa, and Tomotake
More informationJ. Jpn. Soc. Colour Mater., 79 [3], (2006) Anthocyanins : Structural Diversity, Color, and in Vivo Behavior Yuko NAKAGAWA, Takashi ICHIYANAGI,
J. Jpn. Soc. Colour Mater., 79 [3], 113-119 (2006) Anthocyanins : Structural Diversity, Color, and in Vivo Behavior Yuko NAKAGAWA, Takashi ICHIYANAGI, Tetsuya KONISHI and Seiichi MATSUGO J. Jpn. Soc. Colour
More information第十五改正日本薬局方第一追補
316 3 5 7 9 9 9 12 13 14 14 14 23 23 23 24 24 29 29 29 35 37 131 161 173 193 194 198 200 205 3 37 37 37 38 38 38 39 39 40 40 41 42 43 43 45 46 47 48 49 50 51 52 52 53 54 54 54 55 56 58 58 59 60 60 61 61
More information色覚(初組4).pm
733 3 1 520 1 8 4 0.2500 1 30012 1 AB 3 22 3 1 2 http://www.nig.ac.jp/labs/devgen/mou.html 734 1.1 360nm 830nm 380nm 780nm 540nm 580nm 660nm 540nm 660nm Log relative corneal sensitivity 0 1 2 400 500 600
More information& IT/ IT
C O R P O R A T E O U T L I N E 2 8 &-3 25 9 1 1 IT/7 1 2 3 4 6 8 1 11 12 13 14 16 2 21 22 IT 24 25 28 32 34 36 37 38 39 4 41 42 43 44 45 46 &HLDGS. &HLDGS. &HLDGS.1 35, 13, 2,8 1,4 76 97 69-6 7 3 2 2
More information1 911 9001030 9:00 A B C D E F G H I J K L M 1A0900 1B0900 1C0900 1D0900 1E0900 1F0900 1G0900 1H0900 1I0900 1J0900 1K0900 1L0900 1M0900 9:15 1A0915 1B0915 1C0915 1D0915 1E0915 1F0915 1G0915 1H0915 1I0915
More information微粒子合成化学・講義
http://www.tagen.tohoku.ac.jp/labo/muramatsu/mura/main.html E-mail: mura@tagen.tohoku.ac.jp 1 2 3 1m 10cm 1cm 1mm 100 m 10 m 1 m 100nm 10nm 1nm 1 100 m 10 m 1 m 1nm 100nm 10nm 4 5 6 7 1m 10cm 1cm 1mm 100
More informationDatabase Center for Life Science Online Service Vol.48 No.16 (2003)
Database Center for Life Science Online Service Key words Kikuya Kato, E-mail : kkato@bs.aist-nara. ac.jp http://love2.aist-nara.ac.jp Shin Ishii, E-mail : ishii@is.aist-nara.ac.jp http://hawaii.aist-nara.
More information○広島大学職員任免規則\(案\)
1 (14 2 1 (58 2 (9 3 (1012 4 (13 5 (1415 6 (1622 3 1 (23 2 (2425 3 (2627 4 (2829 4 (3033 5 (34 36 6 (37 1641 81 1 ( 1 ( 1641 78 ( 1641 79 ( 1641 80 ( 2 ( 22 49 ( 2 ( 3 101 Hiroshima University (1 ( ( (2
More information○広島大学船員就業規則
1 (14 2 1 (58 2 (9 3 (10 4 (1112 5 (1316 6 (1720 7 (2123 8 (2425 3 (26 4 (27 37 5 (38 6 (3959 7 (60 8 (6166 9 (67 78 10 (79 11 (80 12(81 13 (82 14 (83 15 (84 1641 79 1 ( 1 ( 1641 121 2 ( ( ( 2 ( 22 100
More informationKishu saba-narezushi narezushi Spinacia oleracea
Kishu saba-narezushi narezushi Spinacia oleracea Department of Applied Biology and Chemistry, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1 1 1 Sakuragaoka, Setagaya-ku, Tokyo 156 8502
More information1) Dalton, A. J. et al. : J. Nat. Cancer Inst., 11 : 439, 1950. 2) Fawcett, D. W.: J. Nat. Cancer Inst., 15 :1475, 1955. 3) Oberling, C. et Rouiller, C.: Ann. d'anat. path., 1: 401, 1956. 4) Palade, G.
More information1_alignment.ppt
" " " " n " n n " n " n n n " n n n n " n LGPSSKQTGKGW-SRIWDN! + +! LN-ITKSAGKGAIMRLGDA! " n -------TGKG--------!! -------AGKG--------! " n w w w " n w w " " " 11 12 " n w w w " n w w A! M! O! A!
More information本文/YA1174C
RecF DNA RecA DNA RecA RecF Steve Kowalczykowski Susan Lovett RecJ Mimitou, E.P. & Symington, L.S.Nature,,. Zhu, Z., Chung, W.H., Shim, E.Y., Lee, S.E., & Ira, G. Cell,,. Gravel, S., Chapman, J.R., Magill,
More information寄稿論文 規則性無機ナノ空間が創り出す新しい触媒能 | 東京化成工業
MCM-41 M41 MCM-41 M41 2 3 m 2 /g nm nm Mn Ti Ti H N 2 S Ti-MCM-41, H H N H H 2 2 -Urea, CH 2 Cl 2, H 2 S + S 1b 2b 3b 54%, 58% ee Ti M41 H 2 As 4 ZP 4 ZP ZS ZS 5 Me Me Me Me M41 / 15 mg MeH 1.0 mmol 89%
More informationVol.42 No.1/◇0 目次[三]3.2
Department of Applied Biology and Chemistry, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1 1 1, Sakuragaoka, Setagaya-ku, Tokyo 156 8502 Hitachi Health Management Center, 4 3 16, Osecho,
More informationuntitled
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Int J Radiat Oncol Biol Phys 49 Cancer 101 Int J Radiat Oncol Biol Phys 60 Chest 124 Int J Radiat Oncol Biol Phys 56 Int J Radiat Oncol Biol Phys 49 Chest 124 Int J
More informationDatabase Center for Life Science Online Service [Department of Molecular Physiology, The Tokyo Metropolitan Institute of Medical Science, Honkomagome,
[Department of Molecular Physiology, The Tokyo Metropolitan Institute of Medical Science, Honkomagome, Bunkyo-ku, Tokyo 113, Japan] [Graduate School of Agricultral Bioscien- ces, The University of Tokyo,
More informationDatabase Center for Life Science Online Service Signal transduction of growth factor mediated by heparin heparan sulfate
Signal transduction of growth factor mediated by heparin heparan sulfate 1) Zhu. X.. Komiya, H., Chirino, A.. Faham. S.. Fox, G. M., Arakawa, T., Hsu, B.T., Rees, D. C.: Science. 251, 90-93 (1991)
More information福岡大学人文論叢47-3
679 pp. 1 680 2 681 pp. 3 682 4 683 5 684 pp. 6 685 7 686 8 687 9 688 pp. b 10 689 11 690 12 691 13 692 pp. 14 693 15 694 a b 16 695 a b 17 696 a 18 697 B 19 698 A B B B A B B A A 20 699 pp. 21 700 pp.
More information64) M.L. Gefter, R.L. Russell: J. Mol. Biol., 39, 145 (1969) 65) F. Harada, F. Kimura and S. Nishimura: Biochim. Biophys. Acta., 182, 590 (1969) 65a) F.H.C. Crick: J. Mol, Biol., 19, 548 (1966); M. Nirenberg
More informationDatabase Center for Life Science Online Service School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferati
School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferation and Activation Mechanism of GTP Binding Proteins by the Enzyme 3) Nishizuka, Y.: Nature,
More information肺癌第50巻第4号
1 Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan; 2 Department of Thoracic Surgery, Aichi Cancer Center, Japan;
More information140 120 100 80 60 40 20 0 115 107 102 99 95 97 95 97 98 100 64 72 37 60 50 53 50 36 32 18 H18 H19 H20 H21 H22 H23 H24 H25 H26 H27 1 100 () 80 60 40 20 0 1 19 16 10 11 6 8 9 5 10 35 76 83 73 68 46 44 H11
More information取扱説明書 [F-12C]
F-12C 11.7 1 2 3 4 5 6 7 8 9 10 11 12 13 14 a bc b c d d a 15 a b cd e a b c d e 16 17 18 de a b 19 c d 20 a b a b c a d e k l m e b c d f g h i j p q r c d e f g h i j n o s 21 k l m n o p q r s a X
More informationJuntendo Medical Journal
The hair growth effect of minoxidil Susumu OTOMO, Ph. D. Key words : minoxidil, minoxidil sulfate, hair growth, K+-channel opener, male pattern baldness Dept. of Pharmacology, Research Center Taisho Pharmaceutical
More informationヒビスコール液A カタログ
1 2 3 2002 10 Centers for Disease Control and Prevention CDC A 1. 2. 0.2% 3. 1 A 2 3 4 5 6 7 1 1 1. 2. 3. 2 1. 1 0.2% 10 Pseudomonas aeruginosa ATCC 27853 20 20 Proteus vulgaris ATCC 13315 30 20 Escherichia
More information19) Pearson, J., Southam, G. G. and Holley, R. A.: Survival and transport of bacteria in egg washwater. Appl. Environ. Microbiol., 53, 2060-2065 (1987). 20) Poovaiah, B. W.: Role of calcium in prolonging
More information