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1 pp. D- Frontier Science in Amino Acid and Protein Research D- D- D- D- D-Asp D-Asp D-Asp D- HPLC D- Asp PC D-Asp D- D- D- D-Asp D- D-Asp D- D- D- Asp D-Asp D- D-Asp D-Asp D-Asp D-Asp D- D- Biochemical behavior and function of free D-aspartate in the mammalian body Hiroshi Homma Kitasato University, School of Pharmaceutical Sciences, Laboratory of Biomolecular Science, Shirokane, Minato-ku, Tokyo, Japan D- D L- D- D-amino acid oxidase, DAO, EC D- D-aspartate oxidase, DDO, EC DAO FAD D- - a DDO D- D-Asp D- D- D- D- b
2 D- a D- DAO D- DDO b - - amperometry D- D L- D- D-Asp D L- o- ophthalaldehyde OPA BTCC a ODS OPA N - -L- Boc-L- ODS BTCC b OPA BTCC HPLC Pirkle a -nitrobenzofurazan -nitro- benzoxadiazole NBD b benzofurazan D L- D- C HPLC D L- c D L- d
3 BTCC a BTCC OPA D L- b ODS D L- NBD-F a Pirkle b NBD-F c C Asp d Pirkle a D L-Asp
4 NBD D- naphthalene- -dicarboxaldehyde NDA SDS β- D L- D-Asp D- D-Asp D-Asp D- Asp N - -D- NMDA D-Asp D-Asp HPLC a D- Asp Asp D L D- b D-Asp D-Asp D-Asp BSA D- Asp D-Asp D-Asp L-Asp D-Asp D-Asp L- Asp D-Asp D-Asp D-Asp D-Asp a D-Asp D D-Asp Asp b D- D-Ala D- D-Leu D- D-Ser
5 D-Asp D- Asp D-Asp ahcg D-Asp D-Asp - - b D-Asp L- D-Asp - - D-Asp D-Asp D-Asp hcg D-Asp a D-Asp L-Asp L-Glu D-Glu D-Asp a D-Asp L- Glu L-Glu
6 D-Asp Steroidogenic acute regulatory protein StAR hcg StAR mrna D-Asp L-Asp D-Asp D- Asp D-Asp b D-Asp steroidogenic acute regulatory protein StAR StAR D-Asp StAR mrna D-Asp StAR D- Asp D-Asp - D-Asp oligoasthenoteratospermic donor D-Asp D-Asp D- D-Asp PC HPLC PC Asp D D-Asp D- PC D-Asp D-Asp PC
7 PC D-Asp a PC DMEM TIP DF D-Asp b TIP DF D-Asp D-Asp GH PC MPT T NB- D-Asp D-Asp D L- D- D-Asp Asp D- D-Asp D-Asp D-Asp D-Asp PC D-Asp D-Asp PC MPT D-Asp exocytosis D-Asp volume-sensitive organic anion channel: VSOC PC D-Asp D-Asp PC large densecore vesicle: LDCV K D-Asp SNARE SNAP- RNA D-Asp D-Asp PC D-Asp LDCV D-Asp D-Asp D-Asp D-Asp L-Glu MPT- L-Glu L-Asp D-Asp L-Glu D-Asp
8 PC D-Asp L-Glu D-Asp MPT L-Glu L-Glu D-Asp D-Asp D-Asp L-Glu D-Asp L-Glu PC D-Asp PC L-Glu D-Asp Ca KCl D-Asp PC PC D-Asp LDCV KCl PC PC flat D-Asp PC PC D-Asp mosm D-Asp NPPB DDF PC vesicular transporter D-Asp PC D-Asp PC D-Asp
9 NPPB DDF D-Asp D-Asp D-Asp D-Asp D-Asp D-Asp astrocyte D-Asp ATP D-Asp D-Asp D-Asp PC α TNFα D-Asp NPPB DIDS D-Asp D-Asp D-Asp D-Asp D-Asp D- D-Asp D-Asp D- DDO D-Asp proopiomelanocortin α- α-msh α- MSH D-Asp D-Asp Konno, R., Brückner, H., D Aniello, A., Fisher, G., Fujii, N., & Homma, H. D-Amino Acids: A New Frontier in Amino Acids and Protein Research, Practical Methods and Protocols, Nova Science Publishers, Inc., New York. Hamase, K. J. Chromatogr. B.,,. Imai, K., Fukushima, T., Santa, T., Homma, H., Hamase, K., Sakai, K., & Kato, M. Biomed. Chromatogr.,,. Nimura, N., Fujiwara, T., Watanabe, A., Sekine, M., Furuchi, T., Yohda, M., Yamagishi, A., Oshima, T., & Homma, H. Anal. Biochem.,,. Long, Z., Nimura, N., Adachi, M., Sekine, M., Hanai, T., Kubo, H., & Homma, H. J. Chromatogr. B.,,. Song, Y., Feng, Y., LeBlanc, M.H., Zhao, S., & Liu, Y.-M. Anal. Chem.,,. Miao, H., Rubakhin, S.S., & Sweedler, J.V. Anal. Chem.,,.
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pp. D- D-DAO DAO D- D- D- D- o- DAO-D- D-DAO DAO Hans Krebs FAD X DAO DAO DAO D- Structure and reaction mechanism of D-amino acid oxidase Yasuzo Nishina School of Health Sciences, Kumamoto University,
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pp. D- Frontier Science in Amino Acid and Protein Research L L D D-D-Asp Asp D Asp D L D L D L D L D L D L-D- Racemization of aspartyl residues of proteins in age-related disease Noriko FujiiResearch Reactor
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(http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*, E mail : takaabe@mail.cc.tohoku.ac.jp Taro Tokui, Molecular identification of organic anion transporter
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pp. ATP ε ATP ATP ATP ε Bacillus PS ATP ATP H H µ H ATP ATP ADP µ H ATP FoF -ATP FoF -ATP µ H H ADP ATP H Na On the regulatory role of the epsilon subunit in ATP synthase Yasuyuki Kato-Yamada Department
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pp. E- -SH X in vitro in vivo -SH Structure-based drug development and medical biological application of cathepsin specific inhibitors Nobuhiko Katunuma Institute for Health Sciences, Tokushima Bunri University,Nishihamabouji,
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pp. D- Frontier Science in Amino Acid and Protein Research D- D- N - D- D- D-DAP, EC D-DaaA Ser β- D D- Discovery of D-stereoselective amino acid amidases, and their use in kinetic resolution of amino
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YK250 Human GIP (Active) ELISA FOR RESEARCH LABORATORY USE ONLY FAX: TEL: Website: E-mai
YK250 Human GIP (Active) ELISA FOR RESEARCH LABORATORY USE ONLY 418-0011 2480-1 FAX: 0544-22-2770 TEL: 0544-22-2771 Website: www.yanaihara.co.jp E-mail: ask@yanaihara.co.jp . 2. 3. 4. 56. 7. 812. 12. 1213
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Sulfonylurea Receptors Pancreatic Type: SUR1 Cardiac Type: SUR2A Smooth Muscle Type: SUR2B Kir Channels uka-rp-1/kir6.1 BIR/Kir6.2 1) Ho K, et al : Cloning and expression of an inwardly rectifying ATP-regulated
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